A transgenic mouse model for the detailed morphological study of astrocytes.

abstract：:Aging is a natural biological process associated with several neurological disorders along with the biochemical changes in brain. Aim of the present investigation is to study the effect of carnosine (0.5-2.5μg/kg/day, i.t. for 21 consecutive days) on aging-induced changes in brain regional (cerebral cortex, hippocampu...

journal_title：Neuroscience research

authors： Banerjee S,Poddar MK

更新日期：2015-03-01 00:00:00

abstract：:ATP-sensitive K(+) (K(ATP)) channel subunits SUR2A and SUR2B in the rat brain were investigated by RT-PCR assay, western blot analysis, in situ hybridization histochemistry, and immunohistochemical staining. The results show that the mRNA and protein of SUR2A and SUR2B are expressed in whole rat brain extracts and sel...

journal_title：Neuroscience research

authors： Zhou M,He HJ,Tanaka O,Sekiguchi M,Kawahara K,Abe H

更新日期：2012-10-01 00:00:00

abstract：:Given the amygdala's role in survival mechanisms, and its pivotal contributions to psychological processes, it is no surprise that it is one of the most well-studied brain regions. One of the common methods for understanding the functional role of the amygdala is the use of functional magnetic resonance imaging (fMRI)...

journal_title：Neuroscience research

authors： Murphy JE,Yanes JA,Kirby LAJ,Reid MA,Robinson JL

更新日期：2020-01-01 00:00:00

abstract：:We carried out voltage-sensitive dye imaging of the guinea pig auditory cortex to determine whether the ongoing and spontaneous activities of the cortex exhibit spatial coherence reflecting the tonotopic organization of the cortex. We used independent component analysis and a signal-plus-noise model to extract ongoing...

journal_title：Neuroscience research

authors： Yoshida T,Sakagami M,Katura T,Yamazaki K,Tanaka S,Iwamoto M,Tanaka N

更新日期：2008-05-01 00:00:00

abstract：:Trauma to the spinal cord initiates a series of cellular and biochemical processes that damage both neurons and glia. TGF-beta and its receptors are expressed around the injury site following a spinal cord injury. Here, we report that the intrathecal administration of a neutralizing antibody to TGF-beta1 in rats with ...

journal_title：Neuroscience research

authors： Kohta M,Kohmura E,Yamashita T

更新日期：2009-12-01 00:00:00

abstract：:The effects of substance P (SP) on cholinergic transmission were studied at the neuromuscular junction of frogs by intracellular and voltage-clamp recording methods. Bath application of SP increased the amplitude of end-plate potential (e.p.p.) evoked in either low-Ca2+ -high Mg2+ or curare-containing solution. SP at ...

journal_title：Neuroscience research

authors： Akasu T

更新日期：1986-05-01 00:00:00

abstract：:The subthalamic nucleus occupies a position in the indirect pathway of basal ganglia circuit, which plays an important role in the movement regulation. Zolpidem is an imidazopyridine agonist with a high affinity on the benzodiazepine site of GABA(A) receptors containing alpha 1 subunit. Recently, zolpidem has been rep...

journal_title：Neuroscience research

authors： Chen L,Xie JX,Fung KS,Yung WH

更新日期：2007-05-01 00:00:00

abstract：:Dopaminergic neurons of the substantia nigra pars compacta play a major role in goal-directed behavior and reinforcement learning. The study of their local interactions has revealed that they are connected by electrical synapses. Connexins, the molecular substrate of electrical synapses, constitute a multigenic family...

journal_title：Neuroscience research

authors： Vandecasteele M,Glowinski J,Venance L

更新日期：2006-12-01 00:00:00

abstract：:Mutations in the dynamin family GTPase OPA1 are reportedly the cause of autosomal dominant optic atrophy, the most frequently occurring form of hereditary optic neuropathy. But although the involvement of structural abnormalities of the enzyme in this neurodegenerative disease is clear, little is known about the cell ...

journal_title：Neuroscience research

authors： Misaka T,Murate M,Fujimoto K,Kubo Y

更新日期：2006-06-01 00:00:00

abstract：:We studied developmental changes in respiratory-like C4 activity and respiratory-related neurons in the ventrolateral medulla (VLM) of brainstem-spinal cord preparations from rat fetuses after embryonic day 16 (E16). In addition to respiratory nerve activity, non-respiratory activity was recorded from the C4 ventral r...

journal_title：Neuroscience research

authors： Onimaru H,Homma I

更新日期：2002-03-01 00:00:00

abstract：:Intracellular pH (pH(i)) plays an important role in the regulation of central nervous system function. In the present study, we examined whether hydrogen sulfide (H(2)S), a recently recognized neuromodulator, regulates pH(i) in rat primary cultured glia cells. pH(i) was measured with a fluorescent sensitive dye, BCECF...

journal_title：Neuroscience research

authors： Lu M,Choo CH,Hu LF,Tan BH,Hu G,Bian JS

更新日期：2010-01-01 00:00:00

abstract：:NMDA receptors play an important functional role in the neuron excitability and plasticity. The conditions and consequences of their activation are of interest for many neuroscientists. This investigation was designed to explore an activation of the NMDA receptors of frog tectal neurons in vivo by a burst of spikes of...

journal_title：Neuroscience research

authors： Kuras A,Baginskas A,Batuleviciene V

更新日期：2006-04-01 00:00:00

abstract：:Whole-cell recordings were performed to examine the morphological properties of electrophysiologically classified area postrema (AP) neurons in rat brain slices. Using electrophysiological criteria, AP neurons were subdivided into three groups: (1) cells displaying both the hyperpolarization-activated cation current (...

journal_title：Neuroscience research

authors： Funahashi M,Mitoh Y,Akaike T,Matsuo R

更新日期：2006-01-01 00:00:00

abstract：:Multiple sclerosis (MS) and its animal model, experimental autoimmune encephalomyelitis (EAE), are inflammatory diseases of the central nervous system (CNS) characterized by localized areas of demyelination. MS is believed to be an autoimmune disorder mediated by activated immune cells such as T- and B-lymphocytes and...

journal_title：Neuroscience research

authors： Hisahara S,Okano H,Miura M

更新日期：2003-08-01 00:00:00

abstract：:The neural pathways underlying the respiratory responses elicited by electrical or chemical stimulation of the lateral part of the periaqueductal gray (lPAG) remain unsettled. In the present study, we examined the lPAG projection to neurokinin-1 receptor (NK1R)-immunoreactive (ir) neurons in the ventrolateral medulla ...

journal_title：Neuroscience research

authors： Oka T,Yokota S,Tsumori T,Niu JG,Yasui Y

更新日期：2012-10-01 00:00:00

abstract：:We examined the effects of the odors from mother's milk, other mother's milk and formula milk on pain responses in newborns undergoing routine heelsticks. Forty-eight healthy infants were assigned to four groups, an own mother's breast milk odor group (Own MM), another mother's breast milk odor group (Other MM), a for...

journal_title：Neuroscience research

authors： Nishitani S,Miyamura T,Tagawa M,Sumi M,Takase R,Doi H,Moriuchi H,Shinohara K

更新日期：2009-01-01 00:00:00

abstract：:In previous studies we provided evidence for changes in prolactin (PRL) receptor levels in the male rat brain after continuously infusing morphine using subcutaneously implanted miniosmotic pumps. In this work we have studied the binding of PRL in the male rat brain following morphine administration by both subcutaneo...

journal_title：Neuroscience research

authors： Lai Z,Zhai Q,Liu Z,Roos P,Nyberg F

更新日期：1995-10-01 00:00:00

abstract：:Stem cell-based therapy has recently offered a promising alternative for the remedy of neurodegenerative disorders like Huntington's disease (HD). Herein, we investigated the potential ameliorative effects of implantation of dental pulp stem cells (DPSCs) in 3-nitropropionic acid (3-NP) rat models of HD. In this regar...

journal_title：Neuroscience research

authors： Eskandari N,Boroujeni ME,Abdollahifar MA,Piryaei A,Khodagholi F,Mirbehbahani SH,Siroosi S,Moghaddam MH,Aliaghaei A,Sadeghi Y

更新日期：2020-12-22 00:00:00

abstract：:This study evaluates the efficacy of mifepristone on weight restoration in rats subjected to dietary restriction and methylphenidate administration. 25 female rats aged between 9 and 12 months were divided into 2 groups: 5 controls (exposed only to dietary restriction) and 20 rats that were administered 5 mg/kg/d of m...

journal_title：Neuroscience research

authors： Bou Khalil R,Smayra V,Saliba Y,Hajal J,Bakhos JJ,Souaiby L,Richa S,Tamraz J,Farès N

更新日期：2018-10-01 00:00:00

abstract：:Parkinson's disease (PD) is a multifactorial neurological disorder caused by selective dopaminergic neuronal loss. Quercetin (QC) in combination with piperine (bioenhancer) acts as potential antioxidant, anti-inflammatory and neuroprotective against 6-OHDA rat model of PD. Rats were injected 6-OHDA (8μg/2μl, saline) u...

journal_title：Neuroscience research

authors： Singh S,Kumar P

更新日期：2018-08-01 00:00:00

abstract：:It is well established that cholinergic modulation of functioning of neuronal networks is common in the central nervous system at all scales from neuronal columns to large nuclei. It is involved in various attentional, cognitive and behavioral performances. We have recently demonstrated that a frog retinotectal transm...

journal_title：Neuroscience research

authors： Baginskas A,Kuraite V,Kuras A

更新日期：2012-09-01 00:00:00

abstract：:Type B neurons of the bullfrog sympathetic ganglia were examined to confirm the existence of axon collaterals and the distribution of synaptic contacts using the intracellular horseradish peroxidase (HRP) labeling method. The mean diameter of the perikarya was 60.8 (+/- 11.5 standard deviation; n = 36) X 43.8 (+/- 11....

journal_title：Neuroscience research

authors： Murata Y,Chiba T,Kumamoto E,Kuba K

更新日期：1989-10-01 00:00:00

abstract：:Neural activity on cellular, regional, and behavioral levels shows context-dependence. Here we suggest the processing of input-output relationships in terms divisive normalization (DN), including (i) summing/averaging inputs and (ii) normalizing output against input stages, as a computational mechanism to underlie con...

journal_title：Neuroscience research

authors： Northoff G,Mushiake H

更新日期：2020-07-01 00:00:00

abstract：:Projection fields in the striatum and claustrum from eye movement-evoking cerebral cortices (EMECs) in the cat were investigated using the WGA-HRP tracing method under electrophysiological guidance to place WGA-HRP in the appropriate sites. The EMECs in the frontal cortex, which are located in the medial wall under th...

journal_title：Neuroscience research

authors： Miyashita E,Tamai Y

更新日期：1990-08-01 00:00:00

abstract：:Effect of serotonin on nitric oxide (NO) production in the ventral nerve cord (VNC) of the earthworm Eisenia fetida was investigated by a bio-imaging and an electrochemical technique. In the bio-imaging, the spatial pattern of NO production in VNC was visualized using an NO-specific fluorescent dye, diaminofluorescein...

journal_title：Neuroscience research

authors： Kitamura Y,Naganoma Y,Horita H,Ogawa H,Oka K

更新日期：2001-10-01 00:00:00

abstract：:Huntington's disease (HD) is an autosomal dominant inheritable neurodegenerative disorder currently without effective treatment. It is caused by an expanded polyglutamine (poly Q) tract in the corresponding protein, huntingtin (htt), and therefore suppressing the huntingtin expression in brain neurons is expected to d...

journal_title：Neuroscience research

authors： Wang YL,Liu W,Wada E,Murata M,Wada K,Kanazawa I

更新日期：2005-11-01 00:00:00

abstract：:In the mammalian central nervous system (CNS), transcription factor activator protein 2 (AP-2) is one of the critical regulatory factors for neural gene expression and neural development. As AP-2 has diverged into several subtypes, i.e. AP-2alpha, -2beta, and 2.2, we investigated the distribution of the AP-2 subtypes ...

journal_title：Neuroscience research

authors： Shimada M,Konishi Y,Ohkawa N,Ohtaka-Maruyama C,Hanaoka F,Makino Y,Tamura T

更新日期：1999-04-01 00:00:00

abstract：:Hypnosis often leads people to obey a suggestion of movement and to lose perceived voluntariness. This inexplicable phenomenon suggests that the state of the motor system may be altered by hypnosis; however, objective evidence for this is still lacking. Thus, we used transcranial magnetic stimulation of the primary mo...

journal_title：Neuroscience research

authors： Takarada Y,Nozaki D

更新日期：2014-08-01 00:00:00

abstract：:Exercise appears to improve hippocampal plasticity and cognitive function, leading us to postulate that exercise may activate hippocampal neurons, which in turn increase hippocampal cerebral blood flow (Hip-CBF). Recent studies using laser-Doppler flowmetry (LDF) have shown that Hip-CBF increases with behavior and loc...

journal_title：Neuroscience research

authors： Nishijima T,Soya H

更新日期：2006-03-01 00:00:00

abstract：:The coexistence of varying combinations of substance P (SP), somatostatin (SOM), thyrotropin-releasing hormone (TRH) and met-enkephalin-Arg-Gly-Leu (ENK) with 5-hydroxytryptamine (5-HT) as semiquantitatively revealed by immunocytochemistry in neuronal perikarya of the raphe pallidus et obscurus in the guinea-pig was a...

journal_title：Neuroscience research

authors： Chiba T,Masuko S

更新日期：1989-10-01 00:00:00