Limonoids and carbazole alkaloids from the twigs of Chalcas siamensis Tanaka.

abstract：:The world's rainforests hold untold potential for drug discovery. Rainforest plants are thought to contain evolved defensive active metabolites of greater diversity compared to plants from temperate regions. In recent years, the interest and overall output from pharmaceutical companies on novel antibacterial agents ha...

journal_title：Natural product research

authors： Othman M,Genapathy S,Liew PS,Ch'ng QT,Loh HS,Khoo TJ,Wiart C,Ting KN

更新日期：2011-11-01 00:00:00

abstract：:Four fractions were prepared from the crude extract of Caesalpinia minax Hance and the inhibitory activity of nitric oxide (NO) production release of RAW 264.7 cells stimulated by lipopolysaccharide (LPS) was evaluated. The ethyl acetate (EtOAc) fraction showed obvious inhibitory effect. Bioassay-guided fractionation ...

journal_title：Natural product research

authors： Liu Q,Bai B,Yang DP,Peng SY,Zhu LP,Luo MH,Zhao ZM

更新日期：2018-04-01 00:00:00

abstract：:Alkaloids and phenolic compounds are among the most biologically active natural products from the Jacobaea/Senecio genera (Asteraceae). To isolate original natural products directly from Jacobaea gigantea crude polar extracts, centrifugal partition chromatography (CPC) was used. Previously, we reported the phytochemic...

journal_title：Natural product research

authors： Mezache N,Derbré S,Laouer H,Richomme P,Séraphin D,Akkal S

更新日期：2019-08-01 00:00:00

abstract：:Acetylcholinesterase (AChE) inhibitors have been used for the symptomatic treatment of Alzheimer's disease. Eleven whole plants from Panama belonging to the Lycopodiaceae family have been screened for their anticholinesterase inhibitory and antioxidant activities by a thin-layer chromatography (TLC) bioautography meth...

journal_title：Natural product research

authors： Calderón AI,Simithy-Williams J,Sanchez R,Espinosa A,Valdespino I,Gupta MP

更新日期：2013-03-01 00:00:00

abstract：:Artemisia herba-alba is widely used in traditional medicines for the treatment of several diseases. From the aerial parts organic extract of A. herba-alba, two new compounds, 1,3,8-trihydroxyeudesm-4-en-7α,11βH-12,6α-olide (1) and 5-β-​D-​glucopyranosyloxy​-​7-methoxy-​6H-​benzopyran-​2-​one (2), respectively, togethe...

journal_title：Natural product research

authors： Mohamed TA,Abd El Aty AA,Shahat AA,Abdel-Azim NS,Shams KA,Elshamy AA,Ahmed MM,Youns SHH,El-Wassimy TM,El-Toumy SA,Hegazy MF

更新日期：2019-07-31 00:00:00

abstract：:Sahandinone (1), 12-deoxysalvipisone (2), miltirone (3), 7α-acetoxyroyleanone (4), and labda-7,14-dien-13-ol (5) were isolated from the roots of Salvia rhytidea Benth. (Lamiaceae). Their structures were elucidated by a combination of spectroscopic analyses including EIMS and NMR. The 13C NMR spectroscopic data were re...

journal_title：Natural product research

authors： Jassbi AR,Eghtesadi F,Hazeri N,Ma'sumi H,Valizadeh J,Chandran JN,Schneider B,Baldwin IT

更新日期：2017-02-01 00:00:00

abstract：:The volatile components of Tuber liyuanum were determined by HS-SPME with GC-MS for the first time. The effects of different fibre coating, extraction time, extraction temperature and sample amount were studied to get optimal extraction conditions. The optimal conditions were SPME fibre of Carboxen/PDMS, extraction ti...

journal_title：Natural product research

authors： Liu C,Li Y

更新日期：2017-04-01 00:00:00

abstract：:The Stewartia koreana Nakai (SK) had been used in oriental traditional medicine as a remedy for acute gastroenteritis, liver diseases, quadriplegia and pain. The antioxidant activity guided isolation 80% methyl extract from stems of SK yielded eight phenolic compounds. We evaluated the anti-oxidative and anti-inflamma...

journal_title：Natural product research

authors： Kim MH,Jang JH,Oh MH,Heo JH,Lee MW

更新日期：2014-01-01 00:00:00

abstract：:From analysis by gas chromatography/mass spectrometry (GC/MS), the presence of either 2,4,5-tribromo-1H-imidazole (1) or 3,4,5-tribromo-1H-pyrazole (2) was tentatively identified in lipophilic extracts from the egg masses of three muricid molluscs. Synthesis of these compounds, followed by comparison of the GC retenti...

journal_title：Natural product research

authors： Benkendorff K,Pillai R,Bremner JB

更新日期：2004-10-01 00:00:00

abstract：:Pigeon Pea is a well-received traditional nutritious and medicinal plant in India since ancient times. The plant is identified for its impressive pharmacological activities like antimicrobial, anti-inflammatory, antitubercular, antioxidant, neuroprotective, antihypertensive, antihyperglycemic and anticancer properties...

journal_title：Natural product research

authors： Dinore JM,Farooqui M

更新日期：2020-11-23 00:00:00

abstract：:Two new oleanane triterpenoid saponins, bodiniosides Q (1) and R (2), along with five known saponins, niga-ichigoside F1 (3), 3-O-[β-D-glucopyranosyl]-28-O-[α-L-rhamnopyranosyl -(1→2)-β-D-glucopyranosyl] arjunolic acid (4), asiaticoside E (5), sericoside (6), and bodinioside E (7), were isolated from the aerial parts ...

journal_title：Natural product research

authors： Yang L,Zhang L,Du J,Shao L,Yu F,Li R,Zhong J

更新日期：2020-02-06 00:00:00

abstract：:A new citromycetin analogue, ascomycotin A (1), together with eight known compounds, wortmannilactone E (2), orcinol (3), orsellinic acid (4), isosclerone (5), (3R,4S)-( - )-4-hydroxymellein (6), diorcinol (7), chaetocyclinone B (8) and 2,5-dimethoxy-3,6-di(p-methoxypheny1)-1,4-benzoquinone (9), was isolated from the ...

journal_title：Natural product research

authors： Tian YQ,Lin XP,Liu J,Kaliyaperumal K,Ai W,Ju ZR,Yang B,Wang J,Yang XW,Liu Y

更新日期：2015-01-01 00:00:00

abstract：:The anticancer activity of ethanol extract isolated from Goji berry (EEGB) on T47D human breast cancer cell line has been reported. Cell viability and cell proliferation were examined with the use of BrdU, MTT and NR methods. Induction of apoptosis was assessed by propidium iodide and Hoechst 33342 staining. Expressio...

journal_title：Natural product research

authors： Wawruszak A,Czerwonka A,Okła K,Rzeski W

更新日期：2016-09-01 00:00:00

abstract：:Five new α-pyrones, xylariaopyrones E-I (1-5), along with three known analogues (6-8) were isolated from the cultivation broth of the endophytic fungus Xylariales sp. (HM-1). The structures of the new compounds including their absolute configurations were elucidated by comprehensive spectroscopic methods and quantum E...

journal_title：Natural product research

authors： Yang WW,Lu LW,Zhang XQ,Bao SS,Cao F,Guo ZY,Deng ZS,Proksch P

更新日期：2020-09-30 00:00:00

abstract：:Three compounds, toosendanin (1), kulactone (2) and scopoletin (3), were isolated from either the root bark and/or the stem bark of Melia volkensii. Their structures were determined on the basis of spectroscopic data generated and by comparison with data from the literature. 1 and 2, isolated for the first time from M...

journal_title：Natural product research

authors： Kamau RW,Juma BF,Baraza LD

更新日期：2016-09-01 00:00:00

abstract：:Two new, aramatosides A and B (1 and 2), together with seven known oleanane-type triterpene saponins (3-9) were isolated from the leaves of Aralia armata. Their structures were determined by combination of HR-ESI-MS, 1 D and 2 D NMR spectral data as well as comparison with the previous literature. Compounds 6-9 exhibi...

journal_title：Natural product research

authors： Yen PH,Chuong NTH,Lien GTK,Cuc NT,Nhiem NX,Thanh NTV,Tai BH,Seo Y,Namkung W,Park S,Kim SH,Minh CV,Kiem PV

更新日期：2020-05-22 00:00:00

abstract：:The aim of this work was to provide information about kinetin effects on chemical volatile profile of Curcuma zedoaria (Christm.) Roscoe after several days of plant dormancy release. Rhizomes of C. zedoaria were immersed in four kinetin concentrations (0, 50, 100, 150 mg ml-1, n = 12 by each concentration) for 30 min....

journal_title：Natural product research

authors： Portella RO,Marques MOM,Ono EO,Silva PSSD,Fernandes AM,de Almeida LFR

更新日期：2020-02-21 00:00:00

abstract：:The aerial parts of Baccharis dracunculifolia (BdE) is used in the Brazilian folk medicine to treat inflammatory conditions. Here we examined the ability of free and liposomal BdE to modulate reactive oxygen species generation in human neutrophils in vitro and zymosan-induced acute joint inflammation in Wistar rats. W...

journal_title：Natural product research

authors： de Figueiredo-Rinhel ASG,de Andrade MF,Landi-Librandi AP,Azzolini AECS,Kabeya LM,Bastos JK,Lucisano-Valim YM

更新日期：2019-09-01 00:00:00

abstract：:Phenolic acids, a sub-class of polyphenols, are widely studied. By contrary, 3,4-dihydroxyphenylacetic acid is scarcely studied. For this purpose, a series of 3,4-dihydroxyphenylacetic acid ester and amide derivatives/conjugates were synthesised for the first time. A systematic study has been performed to quantitative...

journal_title：Natural product research

authors： Pagoni A,Vassiliou S

更新日期：2018-06-01 00:00:00

abstract：:Two new flavonoid glycosides, kaempferol 3-O-α-L-rhamnopyranosyl (1→6) (3''-acetyl)-β-D-galactopyranoside 1 and kaempferol 3-O-α-L-arabinopyranosyl-5-O-α-L-rhamnopyranoside 2, along with six known ones 3-8 were isolated from the flowers of Vicia faba L. (Fabaceae). Methanol extract and the isolated compounds were test...

journal_title：Natural product research

authors： Allam AE,Nafady AM,Nakagawa T,Takemoto N,Shimizu K

更新日期：2018-08-01 00:00:00

abstract：:Phytochemical investigation on the stem bark of Shorea maxwelliana yielded five oligostilbenoids identified as α-viniferin (1), maximol A (2), vaticanol A (3), suffruticosol A (4) and vaticanol G (5). Chemotaxonomy of isolated compounds was discussed briefly. Major compounds were tested for neurotoxic and cytotoxic ac...

journal_title：Natural product research

authors： Zawawi NK,Ahmat N,Mazatulikhma MZ,Shafiq RM,Wahid NH,Sufian AS

更新日期：2013-01-01 00:00:00

abstract：:This study evaluates the presence, location and production source of tetrodotoxin (TTX) in two species of pufferfish, Diodon histrix and Arothron hispidus, common to Hawaiian waters. Organs from each fish were analysed for TTX and used to isolate bacteria for evaluation of possible TTX production. Comparative analyses...

journal_title：Natural product research

authors： Campbell S,Harada RM,DeFelice SV,Bienfang PK,Li QX

更新日期：2009-01-01 00:00:00

abstract：:A new isocoumarin, along with 10 known compounds, was isolated from the aerial parts of Aconitum gymnandrum. Their structures were elucidated by spectroscopic methods including extensive 1D and 2D NMR techniques. Among the known compounds, compound 11 was obtained as a natural product for the first time, which was pre...

journal_title：Natural product research

authors： Zhao JQ,Wang YM,Wang S,Dang J,Shi YP,Mei LJ,Tao YD

更新日期：2016-08-01 00:00:00

abstract：:Two new compounds, myrubol (1) and 3-oxo-11α-hydroxyfriedelane (2), were isolated from the roots of Myrica rubra along with eight known compounds (3-10). Their structures were determined through (1)H-NMR and (13)C-NMR spectral data, including 2-D experiments (HMBC, HMQC, (1)H-(1)H COSY and NOESY) and high-resolution m...

journal_title：Natural product research

authors： Li G,Wang D,Xu S

更新日期：2011-01-01 00:00:00

abstract：:The aerial parts of L. cultratus were submitted to a phytopharmacological investigation in order to isolate and identify the major secondary metabolites and evaluate its crude extract, fractions and isolated compounds for antiproliferative activity. Seven compounds were isolated and identified as the chalcones 2',4'-d...

journal_title：Natural product research

authors： da Silva Landim EMBM,Ruiz ALTG,de Carvalho JE,Pomini AM,Pastorini LH,Oliveira Santin SM

更新日期：2019-08-12 00:00:00

abstract：:Juniperus chinensis cv. Kaizuca has extensive pharmacological activities. The cone oils exhibited protein tyrosine phosphatase 1B inhibitory activity in vitro. The IC50 value was 4.49 ± 0.04 μg/mL. A total of 17 compounds were characterised from the cone oils by GC-MS. In order to explain the activity against protein ...

journal_title：Natural product research

authors： Fang C,Gu D,Yang J,Li M,Liu H,Yang Y

更新日期：2018-11-01 00:00:00

abstract：:A new sesquiterpenoid, malayscaphiol (1), and three known compounds, lupeol (2), lupenone (3) and stigmasterol (4), were isolated from the methanolic extract of the stem bark of Scaphium macropodum. The structures of the isolated compounds were determined using several spectroscopic methods, including UV-vis, FT-IR, 1...

journal_title：Natural product research

authors： Al Muqarrabun LM,Ahmat N,Aris SR,Shamsulrijal N,Baharum SN,Ahmad R,Rosandy AR,Suratman MN,Takayama H

更新日期：2014-01-01 00:00:00

abstract：:Three new diterpenoids, liquidambolide A (1) and liquiditerpenoic acids A (2) and B (3), together with 10 known diterpenes were isolated from the resin of Liquidambar formosana Hance, whose structures were elucidated by detailed analysis on the NMR and HR-ESI-MS spectra. ...

journal_title：Natural product research

authors： Shang HJ,Li DY,Wang WJ,Li ZL,Hua HM

更新日期：2014-01-01 00:00:00

abstract：:Commiphora wightii (Arn.) Bhandari, known as guggul, produces a medicinally important gum resin which is used extensively by Ayurvedic physicians to treat various ailments. However, most of the studies on C. wightii have been limited to its gum resin. Comprehensive metabolic profiling of leaves, stem and gum resin sam...

journal_title：Natural product research

authors： Bhatia A,Tripathi T,Singh S,Bisht H,Behl HM,Roy R,Sidhu OP

更新日期：2019-01-01 00:00:00

abstract：:Eleven compounds were isolated from the rhizomes of Paris polyphylla Smith var. yunnanensis. Their structures were elucidated on the basis of rigorous 1D and 2D NMR experiments as well as comparison with the literature data. To the best of our knowledge, compound 1 was only predicted by UPLC/Q-TOF MSE and the NMR spec...

journal_title：Natural product research

authors： Jing S,Wang Y,Li X,Man S,Gao W

更新日期：2017-03-01 00:00:00