Two new oleanane triterpenoid saponins from Elsholtzia bodinieri.

Abstract:

:Two new oleanane triterpenoid saponins, bodiniosides Q (1) and R (2), along with five known saponins, niga-ichigoside F1 (3), 3-O-[β-D-glucopyranosyl]-28-O-[α-L-rhamnopyranosyl -(1→2)-β-D-glucopyranosyl] arjunolic acid (4), asiaticoside E (5), sericoside (6), and bodinioside E (7), were isolated from the aerial parts of Elsholtzia bodinieri. The structures of 1 and 2 were characterized by spectroscopic techniques and chemical evidence as 3-O-β-D- xylopyranosyl-2α, 23-dihydroxy-olean-12-en-28-oic acid 28-O-α-L-rhamnopyranosyl- (1→2)-β-D-glucopyranoside (1) and 3-O-β-D-xylopyranosyl-2α, 23-dihydroxy-olean-12-en-28-oic acid 28-O-[β-D-glucopyranosyl-(1→4)-α-L-rhamnopyranosyl -(1→2)]-β-D-glucopyranoside (2). Compounds 1, 3, and 5 exhibited weak anti-influenza activity against strain A/WSN/33/2009 (H1N1), with inhibition rate of 11.63%, 17.01%, and 16.98%, respectively.

journal_name

Nat Prod Res

journal_title

Natural product research

authors

Yang L,Zhang L,Du J,Shao L,Yu F,Li R,Zhong J

doi

10.1080/14786419.2020.1721489

subject

Has Abstract

pub_date

2020-02-06 00:00:00

pages

1-9

eissn

1478-6419

issn

1478-6427

pub_type

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