Abstract:
:One new flavonoid, 5,7,8,4'-tetrahydroxy-3-methoxyflavone-8-O-β-d-xylopyranoside (2), along with other four known flavones (1, 3-5) were isolated from the aerial parts of Solanum rostratum. 8-hydroxyflavonoid was isolated from series Androceras for the first time. The structure of the new compound 2 was determined on the basis of spectroscopic techniques, including IR, NMR and HRESI-MS. The chemotaxonomic significance of these compounds was summarised.
journal_name
Nat Prod Resjournal_title
Natural product researchauthors
Huang HJ,Ling TJ,Wang HM,Cao AC,Zhang CX,Wei SHdoi
10.1080/14786419.2017.1290621subject
Has Abstractpub_date
2017-08-01 00:00:00pages
1831-1835issue
15eissn
1478-6419issn
1478-6427journal_volume
31pub_type
杂志文章abstract::One new tirucallane-type nortriterpenoid Nortirucallane A (1), together with Chrysoeriol (2) and Isorhamnetin (3), was isolated from the methylene chloride part of Lonicerae japonicae flos. Their structures were elucidated by the detailed analysis of comprehensive spectroscopic data. Compound 3 was isolated from the g...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2017.1299731
更新日期:2017-10-01 00:00:00
abstract::A flavanone has been isolated first time from the stem of Bauhinia variegata, and its structure was identified by colour reactions and spectral analysis. In a search for novel anticancer compounds from medicinal plants, the isolated flavanone was tested for cytotoxic activity against 57 human tumour lines, representin...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786410802553752
更新日期:2009-01-01 00:00:00
abstract::A facile, atom-economic synthesis of isoxazilidino withaferin, a novel hybrid of withaferin A, has been accomplished via two-step reaction of nitrone synthesis followed by nitrone 1,3-dipolar cycloaddition. The reaction is highly chemoselective (preferential reaction only on one of the two double bonds present on with...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2019.1582045
更新日期:2020-08-01 00:00:00
abstract::Camptothecin (CPT), the derivatives of which are used clinically for the treatment of metastatic colon cancer, is isolated from intact plants that can be subjected to environmental fluctuations. In vitro cultures may be an alternate and continuous source for year-round production of CPT. Since CPT production by undiff...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2011.559469
更新日期:2011-10-01 00:00:00
abstract::Aedes aegypti is a primary vector of dengue, a mosquito-borne viral disease infecting 50-100 million people every year. Here, we biosynthesised mosquitocidal silver nanoparticles (AgNP) using the aqueous leaf extract of Crotalaria verrucosa. The green synthesis of AgNP was studied by UV-vis spectroscopy, SEM, EDX and ...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2015.1074230
更新日期:2016-01-01 00:00:00
abstract::The current study focuses on the chemical composition, and evaluation of antioxidant and antibacterial activity of the aerial parts of Centaurea resupinata subsp. dufourii. Using different chromatographic methods nine compounds 1-9 were isolated. The structural identification of isolated compounds was achieved using s...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2020.1715397
更新日期:2020-01-23 00:00:00
abstract::Three new methylated flavonol glucosides: 3-methoxy-7-O-β-(6″-galloylgluco-pyranoside) quercetin (1), 3,4'-dimethoxy-7-O-β-(6″-galloyl-glucopyranoside) quercetin (2) and 3-methoxy-7-O-β-(6″-galloylgluco-pyranoside) kaempferol (3), in addition to six known flavonols, were isolated from the ethyl acetate extract of Fuma...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2013.778848
更新日期:2013-01-01 00:00:00
abstract::Triterpene saponins are throught to be potential anti-tumour agents in many cell types. This study aims to evaluate the cytotoxic activity and mechanism of a triterpene saponin, macranthoside B (MB), isolated from Lonicera macranthoides Hand.-Mazz. (Caprifoliaceae). A cell viability assay showed that MB inhibited cell...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786411003752086
更新日期:2011-02-01 00:00:00
abstract::The aqueous methanolic extracts of Melastoma malabathricum L. exhibited antibacterial activity when assayed against seven microorganisms by the agar diffusion method. Solvent fractionation afforded active chloroform and ethyl acetate fractions from the leaves and the flowers, respectively. A phytochemical study result...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2010.538395
更新日期:2012-01-01 00:00:00
abstract::Toxicity of the pesticide carbofuran (CF) can be alleviated by curcumin, if not for its poor bioavailability. Hence, we investigated the effect of a bioavailable curcumin-galactomannan complex (CGM) on CF-induced neurotoxicity in rats in comparison to that of unformulated standard curcumin (CS). The CF (5 mg/kg b.wt/d...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2018.1514401
更新日期:2020-05-01 00:00:00
abstract::Phenolic acids, a sub-class of polyphenols, are widely studied. By contrary, 3,4-dihydroxyphenylacetic acid is scarcely studied. For this purpose, a series of 3,4-dihydroxyphenylacetic acid ester and amide derivatives/conjugates were synthesised for the first time. A systematic study has been performed to quantitative...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2017.1342090
更新日期:2018-06-01 00:00:00
abstract::Natural products represent a rich source of bioactive compounds that have been historically used to obtain substances with great medicinal potential. The skin of anuran amphibians is a rich source of compounds with a wide range of biological activity. Alzheimer's disease (AD) is a complex disease associated with all k...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2019.1591396
更新日期:2019-03-31 00:00:00
abstract::Chemical investigation of Trogopterus faeces has led to the isolation of seven flavonoids. Their structures were elucidated by chemical and spectral analyses. In an anticoagulative assay, three kaempferol coumaroyl rhamnosides had significant antithrombin activity. This is the first report on the occurrence of flavono...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2010.482057
更新日期:2010-11-01 00:00:00
abstract::Cumin (Cuminum cyminum) is an annual plant from Apiaceae family that is cultivated in Iran as landraces. The most important chemical composition of the cumin essential oil was cuminaldehyde. In this research, the effect of different landraces and growth regulators was evaluated on callus induction, and best callus was...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2016.1272105
更新日期:2017-09-01 00:00:00
abstract::Continued investigation of the marine alga Laurencia claviformis has led to the isolation of pacifenol, a halogenated sesquiterpene as the major metabolite. The microbial transformation of pacifenol is reported. It was cultivated with a marine strain of Penicillium brevicompactum yielding a new compound. The structure...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786410701869440
更新日期:2008-12-01 00:00:00
abstract::Four xanthones were isolated from Gentianopsis paludosa Ma and were identified by modern spectroscopic methods. Cytotoxicity of the four xanthones was tested on HepG2 cells and HL-60 cells by sulphorhodamine B (SRB) assay. Clonogenic survival assay, trypan blue exclusion method, AO/EB staining and DNA fragmentation as...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786410802497398
更新日期:2011-04-01 00:00:00
abstract::In this study, phytochemical composition, antioxidant, enzyme inhibition and cytotoxic activities of methanol and dichloromethane (DCM) extracts of Bougainvillea glabra (B. glabra) flowers were investigated. Methanol extract was found to have higher total bioactive contents and UHPLC-MS analysis of methanol extract re...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2018.1543684
更新日期:2020-09-01 00:00:00
abstract::To obtain more accessible oxidative stress inhibitors, a series of novel spin-labelled derivatives of 3-hydroxybutanolide (2a-d, 3a-d) with the natural active compound (kinsenoside) as the lead compound were designed, synthesised from the nitroxide free radical piperidine (pyrroline) and the main structural unit of ki...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2014.903477
更新日期:2014-01-01 00:00:00
abstract::The chemical investigation of whole plants Piper terminaliflorum Tseng led to the isolation of one new furofuran lignan, 7-methoxyasarinin (1), along with three known amide alkaloids (2-4) as N-3,5-dimethoxy-4-hydroxycinnamoylpyrrole (2), dihydropipercide (3) and 1-[(2E,4E,9E)-10-(3,4-Methylenedioxyphenyl)-2,4,9-undec...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2017.1350671
更新日期:2018-02-01 00:00:00
abstract::A new protein detector of 2,4,6-trinitrophenol (TNP, picric acid) is concisely reported herein for the first time. In brief, the gene of a specific scFv fragment, namely 3.5, was fused separately with the gene of β-lactamase and, subsequently, expressed in the periplasmic space of Escherichia coli, affording in such a...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2020.1860977
更新日期:2020-12-18 00:00:00
abstract::One new furofuran lignan 2-methoxy-9β-hydroxydiasesamin (1), and four analogues (2-5), together with eight alkaloids (6-13), were isolated from the ethanol extract of the aerial part of Clinacanthus nutans. Their structures were elucidated by the detailed analysis of comprehensive spectroscopic data. All the compounds...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2018.1475375
更新日期:2019-05-01 00:00:00
abstract::An aroma chemical emitted from Gerris paludum insularis was analyzed by means of GC and GC-MS. The main constituent was identified as iso amyl alcohol (3-methyl-1-butanol). The chemical showed a characteristic aroma of Gerris paludum insularis. ...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786410310001620655
更新日期:2004-06-01 00:00:00
abstract::A new sesquiterpenoid, malayscaphiol (1), and three known compounds, lupeol (2), lupenone (3) and stigmasterol (4), were isolated from the methanolic extract of the stem bark of Scaphium macropodum. The structures of the isolated compounds were determined using several spectroscopic methods, including UV-vis, FT-IR, 1...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2014.886211
更新日期:2014-01-01 00:00:00
abstract::A new compound, jolynamine (1), was isolated from the marine brown alga Jolyna laminarioides collected from the coast of Karachi, Pakistan. In addition, four known compounds, namely saringosterol (2), loliolide (3), methyl-4-hydroxybenzoate (4) and propyl-4-hydroxybenzoate (5), were isolated for the first time from th...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2010.509722
更新日期:2011-05-01 00:00:00
abstract::A new monoterpenoid indole alkaloid compound (1) and six known monoterpenoid indole alkaloids compounds (2-7) were isolated from the barks of Voacanga africana Staph. The structures were established by spectral analysis as ibogamine-16-carboxylic acid,17,20-didehydro-5,6-dioxo-10-methoxy-methyl ester (1), voacamine (2...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2015.1046132
更新日期:2016-01-01 00:00:00
abstract::The current study introduces a new idea of utilising several bio/chemoinformatics tools in comparing two bio-similar natural molecules viz. curcumin and bisdemethoxycurcumin (BDMC) in order to select a potential nose-to-brain remedy for Alzheimer disease. The comparison comprised several bio/chemo informatics tools. I...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2017.1385017
更新日期:2018-12-01 00:00:00
abstract::This article investigates the effect of microwaves on the amount of volatile compounds Achillea tenuifolia Lam with two methods, headspace single-drop microextraction and microwave-assisted headspace single-drop microextraction (MA-SDME), for the analysis of essential oil. Solvent selection, solvent volume, microwave ...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2015.1079911
更新日期:2016-01-01 00:00:00
abstract::Three species of the genus Homalium - e.g. Homalium nepalense, Homalium tomentosum and Homalium zeylanicum (Flacourtiaceae) - are recorded in India which are confined to the Eastern Ghat hill ranges. While H. zeylanicum is the IUCN red-listed medium-sized tree, the other two are endangered species of medicinal signifi...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2014.987142
更新日期:2015-01-01 00:00:00
abstract::Four fractions were prepared from the crude extract of Caesalpinia minax Hance and the inhibitory activity of nitric oxide (NO) production release of RAW 264.7 cells stimulated by lipopolysaccharide (LPS) was evaluated. The ethyl acetate (EtOAc) fraction showed obvious inhibitory effect. Bioassay-guided fractionation ...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2017.1366480
更新日期:2018-04-01 00:00:00
abstract::This study discusses the similarities and differences between the antioxidant activities of some essential oils: thyme (Thymus vulgaris), basil (Ocimum basilicum), peppermint (Mentha piperita), clove (Caryophyllus aromaticus), summer savory (Satureja hortensis), sage (Salvia hispanica) and lemon (Citrus limon (L.) Bur...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2014.918121
更新日期:2014-01-01 00:00:00