A new briarane-type diterpenoid from the South China Sea Gorgonian Dichotella gemmacea.

abstract：:Lappaconitine is an important alkaloid of the aconite family and its biological activity is closely related to its structure. Through an X-ray structure analysis of hydrated lappaconitine hydrobromide, which was synthesised by us through a new method, the absolute configuration of lappaconitine was determined: monocli...

journal_title：Natural product research

authors： Sun W,Wang Y,Zhang J,Yu K

更新日期：2009-01-01 00:00:00

abstract：:Acetylcholinesterase (AChE) inhibitors have been used for the symptomatic treatment of Alzheimer's disease. Eleven whole plants from Panama belonging to the Lycopodiaceae family have been screened for their anticholinesterase inhibitory and antioxidant activities by a thin-layer chromatography (TLC) bioautography meth...

journal_title：Natural product research

authors： Calderón AI,Simithy-Williams J,Sanchez R,Espinosa A,Valdespino I,Gupta MP

更新日期：2013-03-01 00:00:00

abstract：:Evaluation of in vitro standard antioxidant assays, such as 1,1-diphenyl-2-picrylhydrazyl (DPPH), 2,2'-azino-bis-3 ethylbenzothiozoline-6-sulphonic acid diammonium salt (ABTS+) radical scavenging, lipid peroxidation inhibitory (or thiobarbituric acid formation inhibitory activity) and ferrous ion (Fe+2) chelating acti...

journal_title：Natural product research

authors： Chakraborty K,Raola VK

更新日期：2018-11-01 00:00:00

abstract：:Polyphyllin Ι is a steroidal saponin isolated from the rhizoma of Paris polyphylla. In the present study, we aimed to investigate the anticancer effects of polyphyllin Ι in colorectal cancer and to elucidate the potential underlying molecular mechanisms. Using, CCK8 assay, flow cytometry, laser confocal microscope ana...

journal_title：Natural product research

authors： Yu S,Wang L,Cao Z,Gong D,Liang Q,Chen H,Fu H,Wang W,Tang X,Xie Z,He Y,Peng C,Li Y

更新日期：2018-06-01 00:00:00

abstract：:Three allylbenzenes from Asiasarum heterotropoides, methyleugenol (1), elemicin (2) and gamma-asaron (3) showed suppressive effects on umu gene expression of the SOS response in the Salmonella typhimurium OY1001/1A2 umu test against the mutagen 2-amino-3,4-dimethylimidazo[4,5-f ]quinoline (MeIQ). Gene expression was s...

journal_title：Natural product research

authors： Miyazawa M,Kohno G,Okuno Y,Oda Y

更新日期：2006-06-01 00:00:00

abstract：:The importance of the present study is to find out the phytochemical profile of essential oil (EO) of Artemisia tournefortiana Reichb. and its biological evaluation. Nineteen volatile constituents were identified from EO representing 93.47% of total oil composition. Oxygenated monoterpenes (54.46%) were found to be do...

journal_title：Natural product research

authors： Qadir M,Maurya AK,Agnihotri VK,Shah WA

更新日期：2021-01-01 00:00:00

abstract：:Essential oils (EOs) of chamomile contain several bioactive compounds, including monoterpenes, sesquiterpenes, triterpenes and fatty acids. Hydrodistillation of chamomile EO induces the formation of chamazulene, a bioactive compound. Chamazulene was isolated from the EO by column chromatography. The total antioxidant ...

journal_title：Natural product research

authors： Capuzzo A,Occhipinti A,Maffei ME

更新日期：2014-01-01 00:00:00

abstract：:The aerial portions of Cynara scolymus commonly have been eaten as vegetables or functional foods by the people lived in Mediterranean region. In preliminary antioxidant screening, the rhizome portions (CSR) of this species showed better potential than leaves ones. However, neither phytochemical nor pharmacology studi...

journal_title：Natural product research

authors： Lee CL,Liao KC,Chen CC,Lin YA,Wu TY,Jhan YL,Chen CJ,Yang JC,Wu YC

更新日期：2019-07-30 00:00:00

abstract：:Fungi are important organisms related to the production of antibiotics, many of which are commercially available and used in the clinic to treat infections. Infectious diseases represent a leading cause of death worldwide, being a severe threat to public health, especially with the rise of multi-resistant microorganis...

journal_title：Natural product research

authors： Teles AP,Ataliba GS,Takahashi JA

更新日期：2013-01-01 00:00:00

abstract：:Nerium oleander (NO), a member of the Apocynaceae family, is an ornamental plant. In this study, we evaluated the antiviral activity of hot and cold extract of NO against six different viruses such as herpes simplex virus type 1 (HSV-1), polio virus type 1 (Sb-1), vesicular stomatitis virus (VSV), reovirus type-1 (Reo...

journal_title：Natural product research

authors： Sanna G,Madeddu S,Serra A,Collu D,Efferth T,Hakkim FL,Rashan L

更新日期：2019-03-25 00:00:00

abstract：:The antimicrobial activities of plant extracts have formed the basis of many alternative medicines. In this context, the genus Schinus L. (Anacardiaceae), exhibits many traditional uses in medicine. However, a few studies on the antimicrobial properties of Schinus areira essential oils were conducted. The essential oi...

journal_title：Natural product research

authors： Cutro AC,Castelli MV,López SN,Rosales MA,Hollmann A,Rodriguez SA

更新日期：2019-10-12 00:00:00

abstract：:The compositions of phenolic compounds in 10 cultivars of two mulberry species (Morus atropurpurea Roxb. and Morus alba Linn.) grown in four regions of China were analysed using HPLC-TOF-MS. Results showed that a total of 27 phenolic compounds were identified in these mulberry cultivars. The Taiwan cultivar from the J...

journal_title：Natural product research

authors： Yang J,Zhang X,Jin Q,Gu L,Liu X,Li J,Ni Y

更新日期：2017-05-01 00:00:00

abstract：:A new furostanol saponin, (25R)-26-O-(α-d-glucopyranosyl)-(1→2)-α-l-rhamnopyranosyl-furost-5-ene-3β, 22α, 26-triol-3-O-α-d-glucopyranoside (1), together with four known compounds 2-5 were isolated from the ethanolic extract of the stems of Dendrobium chrysanthum Lindl. The structures of these new compounds were identi...

journal_title：Natural product research

authors： Yang C,Lin W,Zhao L,Cai J

更新日期：2019-09-01 00:00:00

abstract：:Three new diterpenoids, liquidambolide A (1) and liquiditerpenoic acids A (2) and B (3), together with 10 known diterpenes were isolated from the resin of Liquidambar formosana Hance, whose structures were elucidated by detailed analysis on the NMR and HR-ESI-MS spectra. ...

journal_title：Natural product research

authors： Shang HJ,Li DY,Wang WJ,Li ZL,Hua HM

更新日期：2014-01-01 00:00:00

abstract：:Sasa coreana Nakai (SCN) is a medicinal plant commonly used against inflammation. However, the underlined mechanisms against skin inflammation is poorly understood. The present study investigated the effects of SCN leave extract on ear inflammation. To this aim, six-week-old male ICR mice was subjected to 12-O-tetrade...

journal_title：Natural product research

authors： Khan I,Dey DK,Lee JH,Kang SC

更新日期：2020-04-14 00:00:00

abstract：:Mahuang Fuzi Xixin (MFX), a classic recipe in traditional Chinese medicine, belongs to an exterior-relieving formula. For quality control of the MFX products, qualitative analysis using ultra-high performance liquid chromatography with diode-array detector-tandem mass spectrometry (UPLC-PDA-MS/MS) was undertaken. Six ...

journal_title：Natural product research

authors： Zhang L,Wang C,Miao D,Yuan D,Bi K,Yang J,Zhan L

更新日期：2015-01-01 00:00:00

abstract：:Twenty-one phenolic compounds (1-21) including dihydrocinnamic acid, isoflavonoids, flavonoids, coumestans, pterocarpans, chalcones, isoflavan and isoflaven, were isolated from the roots of Glycyrrhiza pallidiflora Maxim. Phloretinic acid (1), chrysin (6), 9-methoxycoumestan (8), isoglycyrol (9), 6″-O-acetylanonin (19...

journal_title：Natural product research

authors： Shults EE,Shakirov MM,Pokrovsky MA,Petrova TN,Pokrovsky AG,Gorovoy PG

更新日期：2017-02-01 00:00:00

abstract：:A new germacrenolide (1) and fourteen known terpenoids (2-15) were isolated from the barks of Magnolia maudiae (Dunn) Figlar (Magnoliaceae). The structure of (7αH,11βH)-2α,8α-dihydroxy-4α,5β-epoxy-germacr-1(10)-en-6α,12-olide (1) was elucidated by physical and spectroscopic data analysis, including 1D, 2D NMR and HR-E...

journal_title：Natural product research

authors： Xianjin S,Sha S,Qi M,Zhang Z,Yang Y,Wu H,Li L,Wang W,Huang A

更新日期：2018-07-01 00:00:00

abstract：:Oil content in sweet and bitter fennels was obtained 12.22% and 14.41%, respectively. The C(18:1 c6), C(18:2), C(18:1 c9) and C(16:0) acids corresponding to approximately 97% of total oil was recorded as principal fatty acids. The ratios of essential oil from sweet and bitter fennels were found similar (average 3.00%)...

journal_title：Natural product research

authors： Coşge B,Kiralan M,Gürbüz B

更新日期：2008-01-01 00:00:00

abstract：:Continuing with our study characterising Senecio nutans Sch. Bip., we have isolated and identified a simple coumarin, scopoletin, that could be relevant for the biological properties of the species related with the ancestral medical uses. This is the first report of scopoletin from S. nutans. In addition, the extract ...

journal_title：Natural product research

authors： Parra C,Soto E,León G,Salas CO,Heinrich M,Echiburú-Chau C

更新日期：2018-03-01 00:00:00

abstract：:β-Glucan, derived from Saccharomyces cerevisiae, is a biological response modifier which affects the innate and adaptive immune responses. The CCR5 chemokine receptor is crucial for immune cell responses. In this study, the effects of the carboxymethylated form of β-glucan (CM-G) on the lymphocyte population of CCR5 g...

journal_title：Natural product research

authors： Magnani M,Castro-Gomez RH,Aoki MN,Gregório EP,Libos F Jr,Morimoto HK,Reiche EM,Watanabe MA

更新日期：2012-01-01 00:00:00

abstract：:A new compound, jolynamine (1), was isolated from the marine brown alga Jolyna laminarioides collected from the coast of Karachi, Pakistan. In addition, four known compounds, namely saringosterol (2), loliolide (3), methyl-4-hydroxybenzoate (4) and propyl-4-hydroxybenzoate (5), were isolated for the first time from th...

journal_title：Natural product research

authors： Khan AM,Noreen S,Imran ZP,Choudhary MI

更新日期：2011-05-01 00:00:00

abstract：:From the seed and leaf extracts of Eryngium species, two new compounds were isolated, along with an aliphatic ketone and several known terpenoids reported from a member of Umbelliferae for the first time. Their structures were elucidated by chemical methods and spectroscopic analysis. ...

journal_title：Natural product research

authors： Muckensturm B,Boulanger A,Farahi M,Reduron JP

更新日期：2010-03-01 00:00:00

abstract：:Morus nigra, popularly known as mulberry, has been traditionally used as anti-diabetic herbal medication. This study focused on hexane fraction from Brazilian M. nigra leaves (Hex-Mn) effects on digestion and absorption of carbohydrate in diabetic mice. The high-performance liquid chromatography (HPLC) analysis was pe...

journal_title：Natural product research

authors： Silva DHAD,Barbosa HM,Beltrão RLA,Silva CFO,Moura CA,Castro RN,Almeida JRGDS,Gomes DA,Lira EC

更新日期：2020-02-24 00:00:00

abstract：:One new tirucallane-type nortriterpenoid Nortirucallane A (1), together with Chrysoeriol (2) and Isorhamnetin (3), was isolated from the methylene chloride part of Lonicerae japonicae flos. Their structures were elucidated by the detailed analysis of comprehensive spectroscopic data. Compound 3 was isolated from the g...

journal_title：Natural product research

authors： Wang X,Zhang J,Li YQ,Du BX,Sun QH,Cao YJ,Jiang HQ,Liu YH,Zhou HL,Rong R

更新日期：2017-10-01 00:00:00

abstract：:A new prenylated xanthone, mangostanaxanthone VIII (7) and six known metabolites: gartanin (1), 1,3,8-trihydroxy-2-(3-methyl-2-butenyl)-4-(3-hydroxy-3-methylbutanoyl)-xanthone (2), rubraxanthone (3), 1,3,6,7-tetrahydroxy-8-prenylxanthone (4), garcinone C (5), and xanthone I (9-hydroxycalabaxanthone) (6) were separated...

journal_title：Natural product research

authors： Ibrahim SRM,Abdallah HM,El-Halawany AM,Nafady AM,Mohamed GA

更新日期：2019-01-01 00:00:00

abstract：:A new androstanoid metabolite, 4α-methyl-9α-methoxyandrosta-8,15-diene-3,17-dione (1), was isolated from a soil fungus Curvularia borreriae (Pleosporaceae) strain HS-FG-237. Its structure was determined by extensive spectroscopic and X-ray diffraction analyses. Compound 1 exhibited poor cytotoxicity toward HCT-116 cel...

journal_title：Natural product research

authors： Liu LF,Zhang H,Qi H,Wang XM,Wang JD,Tan GS

更新日期：2017-05-01 00:00:00

abstract：:Antioxidant, anticholinesterase and antidiabetic activities of three curcuminoids isolated from the Curcuma longa were simultaneously tested and compared in this study. The highest antioxidant power was detected for curcumin with the applied methods. The drug potentials of curcuminoids for Alzheimer's disease were con...

journal_title：Natural product research

authors： Kalaycıoğlu Z,Gazioğlu I,Erim FB

更新日期：2017-12-01 00:00:00

abstract：:The stem bark of Cussonia bancoensis is used traditionally for the treatment of different types of infection and pain. A bioassay guided fractionation of the methanol stem bark extract led to the isolation of five pentacyclic triterpenes and glycosides identified based on spectroscopic data as 23-hydroxyursolic acid (...

journal_title：Natural product research

authors： Mireku EA,Mensah AY,Amponsah IK,Danquah CA,Anokwah D,Kwesi Baah M

更新日期：2020-03-01 00:00:00

abstract：:Trichosanthes dioica Roxb. (Cucurbitaceae), named 'pointed gourd' in English, is a dioecious climber grown in India. This study was aimed at evaluating the laxative activity of the aqueous extract of T. dioica root (TDA) in Swiss albino mice. The laxative activity of TDA (100 and 200 mg kg(-1) body weight per os) was ...

journal_title：Natural product research

authors： Bhattacharya S,Haldar PK

更新日期：2012-01-01 00:00:00