Abstract:
:Chemical investigation of Penthorum chinense resulted in the isolation of two neolignans (1 and 2) together with two known compounds (3 and 4). The structures of compounds 1 and 2 were determined by interpretation of spectroscopic data, and absolute configurations were made based on electronic circular dichroism (ECD). All compounds were evaluated for their antiproliferative activity on hepatic stellate T6 cells (HSC-T6 cells), and 1 and 2 showed moderate activity with IC50 values of 15.3 and 10.1 μM, respectively.
journal_name
Nat Prod Resjournal_title
Natural product researchauthors
Huang D,Dong Z,Sun L,Chen W,Sun Ldoi
10.1080/14786419.2018.1517261subject
Has Abstractpub_date
2020-06-01 00:00:00pages
1515-1520issue
11eissn
1478-6419issn
1478-6427journal_volume
34pub_type
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