Abstract:
:A new androstanoid metabolite, 4α-methyl-9α-methoxyandrosta-8,15-diene-3,17-dione (1), was isolated from a soil fungus Curvularia borreriae (Pleosporaceae) strain HS-FG-237. Its structure was determined by extensive spectroscopic and X-ray diffraction analyses. Compound 1 exhibited poor cytotoxicity toward HCT-116 cells by CCK-8 assay and weak anti-inflammatory activity in an ANA-1 murine macrophages model.
journal_name
Nat Prod Resjournal_title
Natural product researchauthors
Liu LF,Zhang H,Qi H,Wang XM,Wang JD,Tan GSdoi
10.1080/14786419.2016.1272115subject
Has Abstractpub_date
2017-05-01 00:00:00pages
1080-1084issue
9eissn
1478-6419issn
1478-6427journal_volume
31pub_type
杂志文章abstract::Phytochemical investigation of the twigs of Garcinia nobilis led to the isolation of a new xanthone, named l-hydroxy-2,5-dimethoxyxanthone (1), together with 15 known compounds (2-16). The structures of the new and known compounds were established by means of spectroscopic methods and by comparison with previously rep...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2014.903398
更新日期:2014-01-01 00:00:00
abstract::The essential oils of sage leaves (Salvia aucheri Bentham var. canescens Boiss. & Heldr.), growing wild in South Anatolia, were extracted by hydrodistillation and analysed by GC and GC-MS. The percentage yields of the essential oils from sage leaves harvested at different years were 1.0%, 1.3%, 1.3%, 1.0%, 1.4%, 1.5% ...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2011.643309
更新日期:2012-01-01 00:00:00
abstract::The CDC25 phosphatases regulate the cell division cycle by controlling the activity of cyclin-dependent kinases. While screening for inhibitors of phosphatases among natural products we repeatedly found that some polyprenyl-hydroquinones and polyprenyl-furans (furanoterpenoids) (furospongins, furospinosulins) were pot...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/1478641031000111534
更新日期:2004-02-01 00:00:00
abstract::Two new flavonoids, 8-hydroxyisoscoparin (1) and luteolin 7-O-glucoside 4''-sulfate (2), along with eight known flavonoids, including luteolin 7-O-glucoside 2''-sulfate, were isolated and identified from Washingtonia filifera. All compounds were characterized by (1)H-NMR, (13)C-NMR, CI-MS, FABMS and UV. The antioxidan...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/1478641500059276
更新日期:2006-01-01 00:00:00
abstract::Salvia apiana (white sage, Lamiaceae family) plant is native to southern California and parts of Mexico. Some Native American tribes local to this region consider S. apiana to be sacred and burn the leaves as incense for purification ceremonies. The plant has been used to treat sore throats, coughs, chest colds, upper...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2016.1269096
更新日期:2017-09-01 00:00:00
abstract::In the present investigation, the anti-inflammatory activity of a polyphenolic enriched extract of Schima wallichii bark was evaluated in vitro using human peripheral blood mononuclear cells (PBMCs) and in vivo by carrageenan-induced paw oedema assay (acute study) and cotton pallet granuloma assay (chronic study). The...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786410802560732
更新日期:2011-04-01 00:00:00
abstract::Crambe orientalis L. (Brassicaceae), a perennial herb, is indigenous to Iran. The essential oils of flowering tops and leaves of the plant were evaluated by GC-MS. Our results showed that while 2-methyl-5-hexenitrile (19.5%) and benzyl cyanide (16.9%) were the major components of flowering tops oil, the oil of the lea...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786410802611303
更新日期:2009-01-01 00:00:00
abstract::A series of isoquinoline alkaloids including tetrahydroprotoberberines, N-methyl tetrahydroprotoberberines and protoberberines were facile synthesised with protopines as the starting material. All compounds were evaluated for their antibacterial activities against four pathogenic bacteria Escherichia coli, Staphylocco...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2013.867344
更新日期:2014-01-01 00:00:00
abstract::Two new flavonol glycosides, isorhamnetin 3-O-β-glucopyranoside-4'-O-β-xylopyranoside (1) and kaempferol 3-O-β-glucopyranoside -4'-O-β-xylopyranoside (2), were isolated from the defatted aqueous methanol extract of the whole plant Diplotaxis harra along with 12 known flavonols (3-14). They were characterised by chemic...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2013.825914
更新日期:2013-01-01 00:00:00
abstract::Leishmaniasis is caused by parasites of the genus Leishmania. Recent reports about leishmaniasis show a few number of drugs available, indicating the necessity of new drugs. In this study, the ethanol extract and fractions of Pityrogramma calomelanos (L.) link. (Pteridaceae) were assayed to verify the cytotoxicity and...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2012.686911
更新日期:2013-01-01 00:00:00
abstract::The cytotoxicity of six ent-kaurene diterpenoids isolated from the leaves of Isodon japonica (Burm.f.) Hara var. galaucocalyx (maxin) Hara was evaluated against three human tumour HepG2, GLC-82 and HL-60 cell lines through SRB assay, and their DNA damage potential (against HepG2 cell line) was assessed by comet assay....
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786410802267734
更新日期:2011-09-01 00:00:00
abstract::Plant extracts and products have been used for centuries in traditional medicine; for most of them, in addition to the scant scientific credibility, the chemical composition and spectrum of activity are yet to be explored. To put forward this effort and to identify novel antimicrobial agents, the inhibitory activities...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2010.529545
更新日期:2011-07-01 00:00:00
abstract::This study aimed at evaluating the impact of environmental factors on the accumulation of various components in Hedera helix L. folium collected from different European countries. The obtained results of studied samples showed that the antioxidant capacities were in the range of 0.027 to 0.688 mg/g. Contents of active...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2020.1843029
更新日期:2020-11-04 00:00:00
abstract::Commiphora wightii (Arn.) Bhandari, known as guggul, produces a medicinally important gum resin which is used extensively by Ayurvedic physicians to treat various ailments. However, most of the studies on C. wightii have been limited to its gum resin. Comprehensive metabolic profiling of leaves, stem and gum resin sam...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2018.1431629
更新日期:2019-01-01 00:00:00
abstract::From the aerial parts of Citharexylum spinosum L., one new iridoid glucoside, the 7-ss-O-acetate (1) of lamiide, along with four known iridoid glucosides, lamiide (2), lamiidoside (3), duranterectoside C (4), 8-epiloganin (5) and one known lignan glucoside (+)-lyonirenisol-3a-O-ss-D-glucopyranoside (6) were isolated. ...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786410500056694
更新日期:2006-02-01 00:00:00
abstract::Fusarium graminearum Schw. is associated with diseases in seeds and seedlings, mainly in maize, and causes damage to crops and food production. We determined the chemical compositions of essential oils from Pogostemon cablin (Blanco) Benth and Baccharis dracunculifolia DC., and evaluated their antioxidant and antifung...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2020.1802267
更新日期:2020-08-06 00:00:00
abstract::Synsepalum dulcifificum is an evergreen shrub native of tropical West Africa. It is very effective against a variety of diseases. However, the phytochemical investigation on this plant is limited till now. In our current study, seventeen compounds were isolated and identified from the ethyl acetate extract of the leav...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2020.1830394
更新日期:2020-10-09 00:00:00
abstract::Three anthraquinones, Cdc25B phosphatase inhibitors, were isolated from the methanolic extract of the roots of Polygonum multiflorum Thunb. (Polygonaceae). Anthraquinones, physcion (1), emodin (2), and questin (3), inhibited the enzymatic activity of Cdc25B phosphatase with IC(50) values of 62.5, 30, and 34 microg mL(...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786410601012265
更新日期:2007-05-20 00:00:00
abstract::Santolina insularis is a Sardinian endemism that is widely used in traditional medicine. The essential oil was obtained with a yield of 2.7% and is mainly characterized by β-phellandrene (22.6%), myrcene (11.4%) and artemisia ketone (7.6%). The oil significantly reduced NO production without affecting macrophages viab...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2020.1774764
更新日期:2020-06-04 00:00:00
abstract::In an attempt to establish the components responsible for the use of Enantia chlorantha against cutaneous leishmaniasis in local traditional medicine, a well-known palmatine has been isolated in substantial amounts from a methanolic bark extract of this plant species. Palmatine therein obtained exhibited a significant...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786410902726241
更新日期:2009-01-01 00:00:00
abstract::Antibacterial activities of prenylated xanthones from Garcinia mangostana and their synthetic analogues were investigated, and their structure-activity relationships have been studied. γ-Mangostin has shown antibacterial activity against methicillin-resistant Staphylococcus aureus (MRSA), methicillin sensitive Staphyl...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2012.678348
更新日期:2013-01-01 00:00:00
abstract::The ethanol extract of roots of Solidago canadensis yielded eight labdane-type diterpenes. Five of those were new natural compounds (9,13,15,16-bisepoxy-labdane-7-ene-6,15-dione (3a), 13-epi-9,13,15,16-bisepoxy-labdane-7-ene-6,15-dione (3b), 15,16-epoxy-labdane-7,13-diene-6,16-dione (5), 15-ethoxy-9,13,15,16-bisepoxy-...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2011.565005
更新日期:2012-01-01 00:00:00
abstract::The present study has been focused on the extraction of natural pigments from tomato industry waste. At first, different solvents and solvents mixture were compared to determine which one is the best for extracting carotenoids compounds from tomato by-products. A mixture of hexane and acetone gave the highest caroteno...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2016.1226828
更新日期:2017-01-01 00:00:00
abstract::Chemical investigation of the stems of Epigunum griffithianum led to the isolation and identification of a new triterpenoid saponin (1) and two known compounds (epigynosides A (2) and B (3)). These structures were elucidated by means of spectroscopic analysis (1D and 2D NMR, MS, UV, IR) as well as comparison with the ...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2018.1512989
更新日期:2020-05-01 00:00:00
abstract::The ethanolic extract of the fruits of Momordica dioica was studied for its protective and curative effect against gentamicin-induced acute renal injury in albino rats of both sexes. Gentamicin intoxicated group showed significant increase in blood urea (69.48 +/- 4.34) and serum creatinine (3.017 +/- 0.208) from norm...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786410802267569
更新日期:2010-09-01 00:00:00
abstract::Two new xanthone derivatives, penixanthones A (1) and B (2), together with three known compounds, aspenicillide (3), 1,5-dihydroxy-3-methoxy-7-methyl-anthracene-9,10-dione (4) and 1,2-indandiol (5), were isolated from the ethyl acetate extract of a culture of the fungus Penicillium sp. SYFz-1, which was separated from...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2017.1297442
更新日期:2017-10-01 00:00:00
abstract::Since the last decades, socio-economic changes have a key role on eating habits affecting the nutritional status and health of people, in particular children and adolescents. The aim of this study was to compare the diet of student population both normal weight and overweight and obese in order to understand their eat...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2017.1402317
更新日期:2018-08-01 00:00:00
abstract::Cynomorium coccineum is a non-photosynthetic plant that grows in Mediterranean countries and that is amply used in the traditional medicine. The aim of this study was to extend previous studies on the chemical and biological properties of C. coccineum, evaluating the potential antiviral and antiproliferative activity ...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2019.1678613
更新日期:2019-10-17 00:00:00
abstract::Essential oils from aerial parts of Senecio nutans, Senecio viridis, Tagetes terniflora and Aloysia gratissima were analysed by GC-MS and their antifungal activities were assayed on toxigenic Fusarium and Aspergillus species. Sabinene (27.6 ± 0.1%), α-phellandrene (15.7 ± 0.3%), o-cymene (9.6 ± 0.2%) and β-pinene (6.1...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2018.1511555
更新日期:2020-05-01 00:00:00
abstract::Due to the increasing emergence of resistance of bacterial pathogens to current antibiotics, we have examined the marine fungi present in sea sediments obtained 200 m offshore to discover new antibacterial compounds active against multidrug-resistant bacteria. One strain, identified as Emericellopsis minima, was isola...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2017.1344655
更新日期:2018-06-01 00:00:00