A new androstanoid metabolite from a soil fungus Curvularia borreriae strain HS-FG-237.

Abstract:

:A new androstanoid metabolite, 4α-methyl-9α-methoxyandrosta-8,15-diene-3,17-dione (1), was isolated from a soil fungus Curvularia borreriae (Pleosporaceae) strain HS-FG-237. Its structure was determined by extensive spectroscopic and X-ray diffraction analyses. Compound 1 exhibited poor cytotoxicity toward HCT-116 cells by CCK-8 assay and weak anti-inflammatory activity in an ANA-1 murine macrophages model.

journal_name

Nat Prod Res

journal_title

Natural product research

authors

Liu LF,Zhang H,Qi H,Wang XM,Wang JD,Tan GS

doi

10.1080/14786419.2016.1272115

subject

Has Abstract

pub_date

2017-05-01 00:00:00

pages

1080-1084

issue

9

eissn

1478-6419

issn

1478-6427

journal_volume

31

pub_type

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