Isolation and antiproliferative activity of chemical constituents from Asystasia buettneri Lindau.

abstract：:Six sesquiterpenoids and four lignans (1-10) were isolated from the n-BuOH extract of the rhizomes of Atractylodes lancea. Among them, the new sesquiterpenoid glycoside named (4 R, 5S, 7R)-hinesolone-11-O-β-ᴅ-glucopyranoside (1), along with three known compounds (2-4) were first obtained from this genus. All the isola...

journal_title：Natural product research

authors： Long L,Wang L,Qi S,Yang Y,Gao H

更新日期：2020-04-01 00:00:00

abstract：:The structure of pregnane oligoglycosides, namely rocinine (1) and marsdinine (11), which have been isolated from the chloroform soluble extract of the dried stem of Marsdenia roylei, were elucidated using MS, (1)H NMR, (13)C NMR, (1)H-(1)H COSY, HSQC and TOCSY experiments as well as chemical degradation and derivatis...

journal_title：Natural product research

authors： Gupta V,Kumar A,Khare A,Khare NK

更新日期：2009-01-01 00:00:00

abstract：:The chemical composition of the volatile extract (yield ≈ 0.13%, v/w) from the bark of Quercus leucotrichophora (Fagaceae) was analysed for the first time by GC-MS. Twenty-three constituents, amounting to 93.0% of the total detected contents of the volatile extract, were identified. The volatile extract contained appr...

journal_title：Natural product research

authors： Sati SC,Sati N,Sati OP,Biswas D,Chauhan BS

更新日期：2012-01-01 00:00:00

abstract：:Three new phenanthrenone constituents, trigoxyphins U-W (1, 7 and 9), together with eight known ones, trigoxyphin M (2), 6,9-O-dimethyltrigonostemone (3), trigonstemone (4), thrigonosomone B (5), trigonochinene E (6), actephiiol A (8), epiactephilol A (10) and neoboutomannin (11), were obtained from the methanol extra...

journal_title：Natural product research

authors： Li SF,He HP,Hao XJ

更新日期：2015-01-01 00:00:00

abstract：:One new flavonoid, 5,7,8,4'-tetrahydroxy-3-methoxyflavone-8-O-β-d-xylopyranoside (2), along with other four known flavones (1, 3-5) were isolated from the aerial parts of Solanum rostratum. 8-hydroxyflavonoid was isolated from series Androceras for the first time. The structure of the new compound 2 was determined on ...

journal_title：Natural product research

authors： Huang HJ,Ling TJ,Wang HM,Cao AC,Zhang CX,Wei SH

更新日期：2017-08-01 00:00:00

abstract：:Physalins are seco-steroids with a variety of pharmacological activities already described. In this study the pharmacological properties of a standardized concentrated ethanolic extract from Physalis angulata (CEEPA), rich in physalins B, D, F and G, were studied in models of pain and inflammation in mice. Inflammator...

journal_title：Natural product research

authors： do Espírito Santo RF,Lima MDS,Juiz PJL,Opretzka LCF,Nogueira RC,Ribeiro IM,Tomassini TCB,Soares MBP,Villarreal CF

更新日期：2019-12-24 00:00:00

abstract：:The aim of this study was to investigate the influence of both facility location and typology of fish farm on some ecotoxicological, qualitative and reproductive variables in European sea bass Dicentrarchus labrax L. Several variables were investigated: gonado-somatic index (GSI), liver-somatic index (LSI); 7-ethoxyre...

journal_title：Natural product research

authors： Cangialosi MV,Corsi I,Bonacci S,Sensini C,Cicero N,Focardi S,Mazzola A

更新日期：2013-04-01 00:00:00

abstract：:Two new alkaloids 6-hydroxyethyldihydrochelerythrine (1) and 6-hydroxymethyl-7,8-demethylenedihydrochelerythrine (2) together with two analogues named maclekarpine E (3) and 6-hydroxymethyldihydrosanguinarine (4) were detected primarily from the leaves of Macleaya cordata by their characteristic mass spectrometry (MS)...

journal_title：Natural product research

authors： Qing ZX,Yang P,Yu K,Yang XY,Liu JH,Xiang F,Cao HL,Cheng P,Zeng JG

更新日期：2017-07-01 00:00:00

abstract：:Microwave assisted Diels-Alder cycloaddition of 5-Br-N-benzylpyridinone (2) with methyl acrylate is described to gain an easy access to 7-bromo-2-benzyl-3-oxo-2-aza-5 or 6-carbomethoxy bicyclo[2.2.2]oct-7-enes (3)-(6). The preparation of the ibogaine analogue 20-desethyl-(20-endo)-hydroxymethyl-11-demethoxyibogaine (1...

journal_title：Natural product research

authors： Passarella D,Barilli A,Efange SM,Elisabetsky E,Leal MB,Lesma G,Linck VM,Mash DC,Martinelli M,Peretto I,Silvani A,Danieli B

更新日期：2006-07-10 00:00:00

abstract：:Eight phenolic compounds, including two mixtures of two compounds, were isolated from the ethyl acetate extract of leaves and stems of Homalium brachybotrys. They were identified on the basis of spectroscopic data as quercetin-3-O-beta-glucopyranoside, luteolin-7-O-beta-glucopyranoside, 5,6-dihydro-6-beta-glucopyranos...

journal_title：Natural product research

authors： Mosaddik A,Forster PI,Waterman PG

更新日期：2007-11-01 00:00:00

abstract：:Novel derivatives of 4-oxo-3-methylcytisine with phenyl moiety bonded to starting molecule through various spacers were obtained from the 9-amino, -halo, -formyl and 11-halo precursors by reductive alkylation of amines, generation of amide, as well as thio- and carboxamide functions, cross-coupling reactions, aldehyde...

journal_title：Natural product research

authors： Tsypysheva I,Petrova P,Koval'skaya A,Lobov A,Sapozhnikova T,Makara N,Gabdrakhmanova S,Zarudii F

更新日期：2021-01-01 00:00:00

abstract：:A new furanodihydrobenzoxanthone, artomandin (1), together with three other flavonoid derivatives, artoindonesianin C, artonol B, and artochamin A, as well as β-sitosterol were isolated from the stem bark of Artocarpus kemando. The structures of these compounds were determined on the basis of spectral evidence. All of...

journal_title：Natural product research

authors： Ee GC,Teo SH,Rahmani M,Lim CK,Lim YM,Go R

更新日期：2011-06-01 00:00:00

abstract：:Alternanthera brasiliana is popularly known as 'penicillin' and used as an anti-inflammatory and for wound healing. The objective of this work was the phytochemical study of the species by analytical techniques such as LC-MS/MS and GC-MS. Twenty-seven compounds were identified, five by LC-MS and 22 by GC-MS analysis. ...

journal_title：Natural product research

authors： Alencar Filho JMT,Teixeira HAP,Sampaio PA,Pereira ECV,Amariz IAE,Rolim Neto PJ,Rolim LA,Araújo ECDC

更新日期：2020-02-01 00:00:00

abstract：:A new triterpene, javablumine A (1) along with six known ones were isolated from the aerial parts of Sambucus javanica Blume. They were identified as 3β,23-dihydroxy-11α,12α-epoxy-urs-20(30)-en-28,13β-olide (1), ursolic acid (2), pomolic acid (3), oleanic acid (4), 2α-hydroxy-oleanolic acid (5), α-amyrin (6), and lupe...

journal_title：Natural product research

authors： Chen F,Liu DL,Wang W,Lv XM,Li W,Shao LD,Wang WJ

更新日期：2020-10-01 00:00:00

abstract：:Two new cycloartane-type glycosides, caspicuside I and caspicuside II, were isolated along with two known saponins, cycloastragenol and astragaloside IV, from the roots of Astragalus caspicus. As the aglycon group, caspicuside I possesses 3beta,6alpha,16beta,(24S),25-pentahydroxycycloartane (cyclocanthagenol), while c...

journal_title：Natural product research

authors： Fathiazad F,Khosropanah MK,Movafeghi A

更新日期：2010-07-01 00:00:00

abstract：:A new phthalide derivative, xylarphthalide A (1), along with two known compounds (-)-5-carboxylmellein (2) and (-)-5-methylmellein (3), were isolated from the endophytic fungus Xylaria sp. GDG-102 cultured from the Chinese medicinal plant Sophora tonkinensis. Their structures were identified by MS and NMR experiments,...

journal_title：Natural product research

authors： Zheng N,Yao F,Liang X,Liu Q,Xu W,Liang Y,Liu X,Li J,Yang R

更新日期：2018-04-01 00:00:00

abstract：:In this study, Box-Behnken Design was used to optimize the ultrasonic extraction of polysaccharides from quince peels (QPPs) by ascorbic acid and the effect of extraction temperature, extraction time and pH was evaluated. Under optimized conditions of temperature 90 °C, 60 min sonication time and pH = 3.26, the extrac...

journal_title：Natural product research

authors： Dammak MI,Mzoughi Z,Chakroun I,Mansour HB,Le Cerf D,Majdoub H

更新日期：2020-05-01 00:00:00

abstract：:The chemical constituents identified in the essential oils hydrodistilled from the leaves of Amomum gagnepainii T.L.Wu, K.Larsen and Turland and Amomum repoense Pierre ex Gagnep (Zingiberaceae) of Vietnam origin are reported. The chemical analyses were performed by means of gas chromatography-flame ionisation detector...

journal_title：Natural product research

authors： Huong LT,Hung NV,Chung MV,Dai DN,Ogunwande IA

更新日期：2018-02-01 00:00:00

abstract：:Oleiferoside B is a triterpenoid monomer compound, mainly isolated from roots of Camellia oleifera Abel, the underlying mechanism of its antitumour is not clear. In the present study, oleiferoside B potently inhibited SMMC-7721 and MCF-7 cells proliferation and cause cells apoptosis. In addition, it activated an autop...

journal_title：Natural product research

authors： Feng S,Zha Z,Wang Z,Yang P,Wu J,Li X,Xu Q,Liu Y

更新日期：2020-03-18 00:00:00

abstract：:The methanolic extract of the aerial parts of Datura innoxia afforded a new withanolide, daturacin, the structure of which was elucidated as (20R, 22S)-21,24-epoxy-1,6-dioxo-14alpha-methoxy-5beta-witha-2,25(27)-dienolide (1) by an analysis of the spectroscopic data, including extensive NMR experiments. ...

journal_title：Natural product research

authors： Siddiqui BS,Arfeen S,Begum S,Sattar FA

更新日期：2005-09-01 00:00:00

abstract：:Oil content in sweet and bitter fennels was obtained 12.22% and 14.41%, respectively. The C(18:1 c6), C(18:2), C(18:1 c9) and C(16:0) acids corresponding to approximately 97% of total oil was recorded as principal fatty acids. The ratios of essential oil from sweet and bitter fennels were found similar (average 3.00%)...

journal_title：Natural product research

authors： Coşge B,Kiralan M,Gürbüz B

更新日期：2008-01-01 00:00:00

abstract：:In Brazilian folk medicine, Protium heptaphyllum is used to treat inflammatory conditions and to hasten wound repair. This paper aims to investigate the chemical composition and the in vitro antibacterial effects of the essential oils (EOs) obtained from P. heptaphyllum leaves and ripe and unripe fruits against a repr...

journal_title：Natural product research

authors： Cabral RSC,Alves CCF,Batista HRF,Sousa WC,Abrahão IS,Crotti AEM,Santiago MB,Martins CHG,Miranda MLD

更新日期：2020-08-01 00:00:00

abstract：:Essential oils from the leaves, twigs and barks of Bocageopsis pleiosperma Maas were obtained by using hydrodistillation and analysed by using gas chromatography coupled to mass spectrometry. Several compounds (51) were detected and identified, being β-bisabolene the main component in all aerial parts of the plant, wi...

journal_title：Natural product research

authors： Soares ER,da Silva FM,de Almeida RA,de Lima BR,Koolen HH,Lourenço CC,Salvador MJ,Flach A,da Costa LA,de Souza AQ,Pinheiro ML,de Souza AD

更新日期：2015-01-01 00:00:00

abstract：:Two new neoclerodane diterpenoids, barbatin F (1), barbatin G (2) together with four known compounds, scutebata A (3), scutebata B (4), scutebata C (5) and scutebata P (6) were isolated from the whole plant of Scutellaria barbata D.Don. Their structures were elucidated on the basis of spectroscopic studies. In vitro c...

journal_title：Natural product research

authors： Wang M,Chen Y,Hu P,Ji J,Li X,Chen J

更新日期：2020-05-01 00:00:00

abstract：:The aim of this work was to provide information about kinetin effects on chemical volatile profile of Curcuma zedoaria (Christm.) Roscoe after several days of plant dormancy release. Rhizomes of C. zedoaria were immersed in four kinetin concentrations (0, 50, 100, 150 mg ml-1, n = 12 by each concentration) for 30 min....

journal_title：Natural product research

authors： Portella RO,Marques MOM,Ono EO,Silva PSSD,Fernandes AM,de Almeida LFR

更新日期：2020-02-21 00:00:00

abstract：:In the present investigation, the anti-inflammatory activity of a polyphenolic enriched extract of Schima wallichii bark was evaluated in vitro using human peripheral blood mononuclear cells (PBMCs) and in vivo by carrageenan-induced paw oedema assay (acute study) and cotton pallet granuloma assay (chronic study). The...

journal_title：Natural product research

authors： Dewanjee S,Mandal V,Sahu R,Dua TK,Manna A,Mandal SC

更新日期：2011-04-01 00:00:00

abstract：:This study was performed to investigate the effect of ethanol extract from Saururus chinensis (Lour.) Baill on liver function, plasma lipid composition and antioxidant system with high-fat diet for 4 weeks. Rats were divided into the following five groups; untreated control group (normal), treated with 0.5% SE (normal...

journal_title：Natural product research

authors： Yu MH,Im HG,Lee JW,Bo MH,Kim HJ,Kim SK,Chung SK,Lee IS

更新日期：2008-02-15 00:00:00

abstract：:Citrinin dimeric derivatives are bioactive polyketides previously reported from Penicillium, Aspergillus and Monascus fungi species. Due to the large distance between the stereogenic centers of the two monomer units, it was difficult to determine the absolute configuration of the whole molecule (1). In previous work, ...

journal_title：Natural product research

authors： Cao F,Sun TT,Yang JK,Zhao GZ,Liu QA,Hu LD,Ma ZY,Zhu HJ

更新日期：2019-08-01 00:00:00

abstract：:The CDC25 phosphatases regulate the cell division cycle by controlling the activity of cyclin-dependent kinases. While screening for inhibitors of phosphatases among natural products we repeatedly found that some polyprenyl-hydroquinones and polyprenyl-furans (furanoterpenoids) (furospongins, furospinosulins) were pot...

journal_title：Natural product research

authors： Erdogan-Orhan I,Sener B,de Rosa S,Perez-Baz J,Lozach O,Leost M,Rakhilin S,Meijer L

更新日期：2004-02-01 00:00:00

abstract：:The cholesteryl ester transfer protein (CETP), inhibition of which assists in maintaining a high level of high-density lipoprotein cholesterol in the blood, is a target for anti-atherosclerosis treatments. Orange monascus pigment was produced by a Monascus species in a 5 L jar fermenter and various derivative compound...

journal_title：Natural product research

authors： Jang H,Choe D,Shin CS

更新日期：2014-01-01 00:00:00