Physalis angulata concentrated ethanolic extract suppresses nociception and inflammation by modulating cytokines and prostanoids pathways.

abstract：:The microbial transformation of androst-4-ene-3,17-dione (4-AD; I) by three fungal species, involved Fusarium solani BH1031, Aspergillus awamori MH18 and Mucor circinelloides W12, has been studied. The latter two fungi were studied for the first time on biotransformation of 4-AD. The main product obtained by Fusarium ...

journal_title：Natural product research

authors： An X,Gao P,Zhao S,Zhu L,You X,Li C,Zhang Q,Shan L

更新日期：2021-02-01 00:00:00

abstract：:Several factors affect the vegetative growth of fungi, such as temperature, pH, and culture medium. In addition to mycelial growth, these factors affect metabolite production. There are limited studies that have identified the metabolites produced by the fungus Bjerkandera adusta, which have potential biotechnological...

journal_title：Natural product research

authors： Rech KS,de Oliveira CF,Moura PF,de Oliveira CDSP,Hirota BCK,de Oliveira M,Rüdiger AL,de Sá EL,Miguel OG,Auer CG,Miguel MD

更新日期：2020-05-06 00:00:00

abstract：:Evaluation of in vitro standard antioxidant assays, such as 1,1-diphenyl-2-picrylhydrazyl (DPPH), 2,2'-azino-bis-3 ethylbenzothiozoline-6-sulphonic acid diammonium salt (ABTS+) radical scavenging, lipid peroxidation inhibitory (or thiobarbituric acid formation inhibitory activity) and ferrous ion (Fe+2) chelating acti...

journal_title：Natural product research

authors： Chakraborty K,Raola VK

更新日期：2018-11-01 00:00:00

abstract：:This study evaluates the presence, location and production source of tetrodotoxin (TTX) in two species of pufferfish, Diodon histrix and Arothron hispidus, common to Hawaiian waters. Organs from each fish were analysed for TTX and used to isolate bacteria for evaluation of possible TTX production. Comparative analyses...

journal_title：Natural product research

authors： Campbell S,Harada RM,DeFelice SV,Bienfang PK,Li QX

更新日期：2009-01-01 00:00:00

abstract：:This paper aims to investigate, for the first time, physicochemical characteristics and antioxidant capacity of Psidium myrtoides ripe and unripe fruit. In addition, essential oil was extracted from fresh leaves (PM-EO) collected in dry and rainy seasons to investigate the influence of seasonality and, after that, to ...

journal_title：Natural product research

authors： Dias ALB,Batista HRF,Sousa WC,Bailão EFLC,Rocha JD,Sperandio EM,Fernandes CC,Souchie EL,Miranda MLD

更新日期：2020-11-09 00:00:00

abstract：:Chemical investigation of the lichen Parmotrema dilatatum led to the isolation of a new chlorinated compound, named dilatatone (1), along with a known compound, sernanderin (2). Their chemical structures were determined by analysis of their 1 D and 2 D NMR spectra, HRESIMS, and ECD data. Both compounds showed weak α-g...

journal_title：Natural product research

authors： Phan HV,Devi AP,Le HD,Nguyen TT,Nguyen HH,Le TT,Nguyen TH,Sichaem J,Duong TH

更新日期：2020-01-27 00:00:00

abstract：:A new compound decomposed from ginkgolide B(GB) is discovered and identified by MS and UV spectrum. It is the dehydrate of GB, which was named as ginkgolide K before. Differently, it cannot exist independently, but only in equilibrium with GB. It is found first time that 3-hydroxy is active in some solvent. ...

journal_title：Natural product research

authors： Yuan C,Pan J,Hu X

更新日期：2008-01-01 00:00:00

abstract：:Two new ditetrahydrofuran lignans, named sieverlignans A and B (1 and 2), together with six known ones (3-8), were isolated from the aerial parts of Artemisia sieversiana. Their structures were established on the basis of spectroscopic analysis including HRMS, NMR spectra and circular dichroism experiments. All the co...

journal_title：Natural product research

authors： Zhou XD,Xu XW,Shi LY,Chen SH,Zeng KW,Tu PF

更新日期：2020-01-13 00:00:00

abstract：:Six new compounds, including three terpenoids (1-3) and three lignans (4-6), were isolated from the 95% EtOH extract of the twigs of Tripterygium hypoglaucum. Their structures were determined on the basis of extensive spectroscopic analysis. 9'-O-benzoyl-lariciresinol (4) showed weak cytotoxicity against HepG2/Adr cel...

journal_title：Natural product research

authors： Zheng H,Wang L,Yang T,Liu D,Li HM,Chen XQ,Li RT

更新日期：2020-07-01 00:00:00

abstract：:The isolation from olive pulp of a diacylglycerol showing an oleic as well as an elenoic acid residue, the latter probably derived from a natural enzymatic oleuropein hydrolysis, is reported. The given structure is supported by 1H- and 13C-NMR data. ...

journal_title：Natural product research

authors： Marra C,Giordano ME

更新日期：2005-01-01 00:00:00

abstract：:This study was performed to investigate the effect of ethanol extract from Saururus chinensis (Lour.) Baill on liver function, plasma lipid composition and antioxidant system with high-fat diet for 4 weeks. Rats were divided into the following five groups; untreated control group (normal), treated with 0.5% SE (normal...

journal_title：Natural product research

authors： Yu MH,Im HG,Lee JW,Bo MH,Kim HJ,Kim SK,Chung SK,Lee IS

更新日期：2008-02-15 00:00:00

abstract：:Six chemical constituents were isolated from Enicosanthum cupulare (King) Airy-Shaw. The structures of the isolated compounds were determined using 1D, 2D-NMR and were found to be identical to those previously reported for these compounds. Three aporphine alkaloids, O-methylmoschatoline, liriodenine and oxostephanine ...

journal_title：Natural product research

authors： Fujita S,Ninomiya M,Efdi M,Ohguchi K,Nozawa Y,Koketsu M

更新日期：2010-10-01 00:00:00

abstract：:Phytochemical investigation of n-hexane extract of Salvia sahendica by normal phase column chromatography resulted in the isolation of six compounds. Structures were established by 1D and 2D NMR spectroscopy, and HRMS, as a new norditerpene 1, and known terpenoids, sclareol (2), oleanolic acid (3), β-sitosterol (4), s...

journal_title：Natural product research

authors： Mofidi Tabatabaei S,Salehi P,Moridi Farimani M,Neuburger M,De Mieri M,Hamburger M,Nejad-Ebrahimi S

更新日期：2017-08-01 00:00:00

abstract：:A new oligostilbenoid, diptoindonesin C, has been isolated from the tree bark of Shorea pinanga Scheff., along with the two known oligostilbenoids gnetin H and hopeaphenol, and a known coumarin scopoletin. The new oligostilbenoid was moderately active against brine shrimps Artemia salina. ...

journal_title：Natural product research

authors： Syah YM,Hakim EH,Ghisalberti EL,Jayuska A,Mujahidin D,Achmad SA

更新日期：2009-01-01 00:00:00

abstract：:Phebaclavin I, a novel 3-prenylated coumarin, was isolated from the aerial parts of Phebalium aff. tuberculosum (Rutaceae) together with five known related compounds, Phebaclavin A, B, D, G, H. The structure of phebaclavin I was established by spectroscopic methods. Several other known coumarins were obtained, includi...

journal_title：Natural product research

authors： Roux D,Muyard F,Girard C,Colombain M,Tillequin F,Waterman PG,Bévalot F

更新日期：2006-03-01 00:00:00

abstract：:Extracts obtained from Cyrtocarpa procera Kunth were evaluated to determine their toxicity on Artemia salina Leach. All the extracts showed a significant activity. Bioguided fractionation of these extracts led to the isolation of beta-sitosterol and the identification of 1,3-propyl-dipentadecanoate, 3-hydroxypropyl-9-...

journal_title：Natural product research

authors： Rodríguez-López V,Aguirre-Crespo F,Salazar L,Estrada-Soto S

更新日期：2006-01-01 00:00:00

abstract：:Six known metabolites, two new isocoumarins 4 and 8, and one new highly substituted benzoic acid derivative 9 were isolated from the ethyl acetate culture extract of a fungal endophyte, Scytalidium sp. In addition, another new benzoic acid 10 with an unusual 1,2-dicarbonyl side chain was indirectly identified from its...

journal_title：Natural product research

authors： Krohn K,Sohrab MH,Aust HJ,Draeger S,Schulz B

更新日期：2004-06-01 00:00:00

abstract：:Phytochemical investigation of the aerial parts of Eriope blanchetii and E. latifolia (Lamiaceae) yielded podophyllotoxin, as well as the aryltetralin lignans α- and β-peltatin and yatein. Oleanolic, ursolic and epikatonic acids were also isolated. This is the first occurrence of podophyllotoxin in the family. ...

journal_title：Natural product research

authors： Santos EO,Lima LS,David JM,Martins LC,Guedes ML,David JP

更新日期：2011-09-01 00:00:00

abstract：:One new flavonoid, 5,7,8,4'-tetrahydroxy-3-methoxyflavone-8-O-β-d-xylopyranoside (2), along with other four known flavones (1, 3-5) were isolated from the aerial parts of Solanum rostratum. 8-hydroxyflavonoid was isolated from series Androceras for the first time. The structure of the new compound 2 was determined on ...

journal_title：Natural product research

authors： Huang HJ,Ling TJ,Wang HM,Cao AC,Zhang CX,Wei SH

更新日期：2017-08-01 00:00:00

abstract：:The aerial parts of L. cultratus were submitted to a phytopharmacological investigation in order to isolate and identify the major secondary metabolites and evaluate its crude extract, fractions and isolated compounds for antiproliferative activity. Seven compounds were isolated and identified as the chalcones 2',4'-d...

journal_title：Natural product research

authors： da Silva Landim EMBM,Ruiz ALTG,de Carvalho JE,Pomini AM,Pastorini LH,Oliveira Santin SM

更新日期：2019-08-12 00:00:00

abstract：:Cinobufagin was one of the important cardenolidal steroids and a major component of Chan'Su, a famous traditional Chinese medicine. The urinary metabolites of cinobufagin after single oral doses of 25 mg kg⁻¹ in rats were investigated. Eleven metabolites were isolated and purified by liquid-liquid extraction, open-col...

journal_title：Natural product research

authors： He X,Hu H,Wu Y,Zeng X

更新日期：2012-01-01 00:00:00

abstract：:Two new norsesquiterpenes were isolated from the extracts of the roots and rhizomes of Ligularia lapathifolia (Franch.) Hand.-Mazz. Their structures were identified as 2-acetyl-3a-methyl-5-(2-methyl-but-2-enoyloxy)-3a,4,5,6,7,7a-hexahydro-H-indene-4-carboxylic acid (1) and 2-acetyl-8a-methyl-2-(2-methyl-but-2-enoyloxy...

journal_title：Natural product research

authors： Li YS,Wang ZT,Zhang M,Chen JJ,Luo SD

更新日期：2004-04-01 00:00:00

abstract：:A new 1,4-napthoquinone derivative, namely (S)-(-)-3-(8-hydroxy-1,4-dioxo-1,4-dihydro-naphthalen-2-yl)-3-(4-hydroxy-3-methoxyphenyl)-propionic acid methyl ester (1), was isolated from the roots of Juglans mandshurica Maxim. The structure was identified based on HR-ESI-MS, 1D and 2D NMR spectroscopic methods. ...

journal_title：Natural product research

authors： Jiang Z,Diao S,Li R,Zhou W,Sun J,Zhou Y,Jin Y,Jin M,Li G

更新日期：2018-05-01 00:00:00

abstract：:Meliquercifolins A (1), and B (2), two new coumarins are bearing an acetophenone derivative were isolated from the leaves of Melicope quercifolia along with three known compounds, melicodenines E (3), F (4) and I (5). Structures of two new compounds were identified based on spectroscopic analyses (UV, HR-ESI-MS, 1 D a...

journal_title：Natural product research

authors： Saputri RD,Tjahjandarie TS,Tanjung M

更新日期：2019-07-22 00:00:00

abstract：:A new eremophilane sesquiterpene, capnodiumone (1), along with five known eremophilane sesquiterpenes (2-6) and eight other compounds (7-14), have been isolated from a mangrove-associated fungus Capnodium sp. SZ-F22. The chemical structures were elucidated on the basis of extensive spectroscopic analysis. The broth ex...

journal_title：Natural product research

authors： He H,Ma Z,Wang Q,Liu Y,Xu H

更新日期：2016-07-01 00:00:00

abstract：:Two new flavanone glycosides have been isolated from the water soluble part of Veratrum nigrum L., belonging to the family Lilica. The structures of 3',4'-dimethoxyl-quercitrin and 4'-methoxyl-glucotricin have been established with the aid of extensive NMR spectroscopic studies. ...

journal_title：Natural product research

authors： Li HL,Tang J,Liu RH,Zhang C,Zhang WD

更新日期：2009-01-01 00:00:00

abstract：:An alternative method for the synthesis of the 8-methyl-1-tetralone from the commercially available 5-methoxy-1-tetralone has been developed. The transformation involves eight steps and affords an overall yield 25%. ...

journal_title：Natural product research

authors： Poon PS,Bedoya L,Churio GJ,Banerjee AK

更新日期：2014-01-01 00:00:00

abstract：:Phytochemical investigations on Phyllanthus emblica have resulted in the isolation of the two new flavonoids, kaempferol-3-O-alpha-L-(6''-methyl)-rhamnopyranoside (1) and kaempferol-3-O-alpha-L-(6''-ethyl)-rhamnopyranoside (2). Their structures were determined on the basis of extensive spectroscopic studies including ...

journal_title：Natural product research

authors： Habib-ur-Rehman,Yasin KA,Choudhary MA,Khaliq N,Atta-ur-Rahman,Choudhary MI,Malik S

更新日期：2007-07-20 00:00:00

abstract：:From the seed and leaf extracts of Eryngium species, two new compounds were isolated, along with an aliphatic ketone and several known terpenoids reported from a member of Umbelliferae for the first time. Their structures were elucidated by chemical methods and spectroscopic analysis. ...

journal_title：Natural product research

authors： Muckensturm B,Boulanger A,Farahi M,Reduron JP

更新日期：2010-03-01 00:00:00

abstract：:The methanol extract of the root cortex of Paeonia suffruticosa afforded two new monoterpene glycosides, paeoniside A (1) and paeoniside B (2), and three known monoterpene glycosides, paeoniflorin (3), benzoylpaeoniflorin (4) and 4-O-methyl-paeoniflorin (5). Their structures were elucidated on the basis of spectroscop...

journal_title：Natural product research

authors： Zhu X,Fang ZH

更新日期：2014-01-01 00:00:00