Abstract:
:Meliquercifolins A (1), and B (2), two new coumarins are bearing an acetophenone derivative were isolated from the leaves of Melicope quercifolia along with three known compounds, melicodenines E (3), F (4) and I (5). Structures of two new compounds were identified based on spectroscopic analyses (UV, HR-ESI-MS, 1 D and 2 D NMR). Cytotoxic activities of compounds (1-5) towards three human cancer cells (HeLa, MCF-7, P-388), compounds 1, 4 and 5 showed very potent activity against Hela cells with IC50 values 2.6; 0.8; 1.1 μM, respectively.
journal_name
Nat Prod Resjournal_title
Natural product researchauthors
Saputri RD,Tjahjandarie TS,Tanjung Mdoi
10.1080/14786419.2019.1644634subject
Has Abstractpub_date
2019-07-22 00:00:00pages
1-6eissn
1478-6419issn
1478-6427pub_type
杂志文章abstract::To search for antifungal leads, the metabolites of an insect-derived fungus Fusarium lateritium ZMT01 were investigated, providing five sesquiterpenes (1-5), including new molecules microsphaeropsisins D and E (1 and 2). The evaluated antifungal activities in vitro which are higher than the positive control triadimefo...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2021.1872569
更新日期:2021-01-15 00:00:00
abstract::Azadirachtin-A (Aza-A, figure 1) was subjected to a variety of synthetic transformations and the antifeedant activity and toxicity of the azadirachtin derivatives were assessed against second instar larvae Spodoptera litura on castor leaves in comparison with the crude material containing 9.14% Aza-A, as well as relat...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786410512331330558
更新日期:2005-07-01 00:00:00
abstract::Eight known abietane diterpenes (1-8) were isolated for the first time from Abies numidica cones (Pinaceae). The structures of all compounds were established by means of 1D and 2D NMR, and UV spectral analyses. The hydromethanolic extract of A. numidica cones was tested for its antimicrobial activity against 17 gram-p...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2016.1190723
更新日期:2017-03-01 00:00:00
abstract::The phytochemical study of the aerial parts of Viburnum chinshanense Graebn., a species growing in Western and Central China, led to the isolation of six iridoid glucosides: the novel 10,2'-diacetylpatrinoside, 1, and the known 2'-acetyldihydropenstemide, 2'-trans- p-coumaroyl-dihydropenstemide, 2'-acetylpatrinoside, ...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786410500056678
更新日期:2006-07-10 00:00:00
abstract::This study investigated the pharmacokinetics of hesperidin (HP), ferulic acid (FA) and p-coumaric acid (CA) in rat plasma after oral administration of Portulaca oleracea L. extract (POE). The plasma concentrations were determined by HPLC with vitexin-2″-O-rhamnoside (VR) as internal standard. The calibration curves we...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2011.648193
更新日期:2012-01-01 00:00:00
abstract::Essential oils (EOs) of chamomile contain several bioactive compounds, including monoterpenes, sesquiterpenes, triterpenes and fatty acids. Hydrodistillation of chamomile EO induces the formation of chamazulene, a bioactive compound. Chamazulene was isolated from the EO by column chromatography. The total antioxidant ...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2014.931393
更新日期:2014-01-01 00:00:00
abstract::The use of natural products as a diet supplement is increasing worldwide but sometimes is not followed by adequate sanitary controls and analyses. Twenty samples of pills and capsules of lyophilised cyanobacteria (blue-green algae), commercialised in Italy as dietary supplements, were found positive at the Vibrio fisc...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786410500410859
更新日期:2006-07-20 00:00:00
abstract::Methanolic extracts of 18 Thai plants from Doi Tung, the north of Thailand, were examined for brine shrimp lethality and antioxidative activity using 1,1-diphenyl-2-picrylhydrazyl (DPPH) assay. In brine shrimp lethality, the highly toxic plant extracts were Mitrephora wangii (LC(50) 14.8 µg mL(-1)) and Hydrocotyle jav...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2010.534469
更新日期:2012-01-01 00:00:00
abstract::A new propanamide analogue (1), along with one known alkaloid (2) and four known diketopiperazines (3-6), was isolated from a cultured broth of the actinomycete Streptomyces sp. Q24 that was obtained from a sample of mangrove soil. The structures of these isolates were characterised as 3-acetylamino-N-2-thienyl-propan...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2016.1253079
更新日期:2017-06-01 00:00:00
abstract::This study evaluated the roles of zeatin (2 mg/L) on direct organogenesis, phytochemical compounds, antioxidant activity, and cytotoxic activity in regenerated shoots of red cabbage. The results revealed that the extract of explant treated by 2 mg/L zeatin gives the highest content of total phenolics (5.18 mg gallic a...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2018.1508145
更新日期:2020-03-01 00:00:00
abstract::A new pterocarpan, named velucarpin D (1), along with nine known pterocarpans (2-10) were isolated from the stems of Dalbergia velutina. Their structures were determined by spectroscopic analysis. All isolated compounds were evaluated for their cytotoxicity against five human cancer cell lines (KB, HeLa S-3, MCF-7, He...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2020.1749613
更新日期:2020-04-05 00:00:00
abstract::A new isoflavonoid, excelsanone (2), was isolated from the ethyl acetate extract of Erythrina excelsa stem bark, together with three known compounds namely 6,8-diprenylgenistein (3), β-sitosterol (1) and sitosteryl-β-D-glucopyranoside (4). Their structures were elucidated using spectroscopic methods (HR-ESI-MS, NMR an...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2018.1495639
更新日期:2020-03-01 00:00:00
abstract::Okra, Abelmoschus esculentus L. (Moench), also known as Lady's Fingers, gombo, or bamje, is an annual plant belonging to the Malvaceae family. Traditional olistic medicine since centuries directly associates this plant and its parts to a beneficial health hypoglycemic effect. Since the abscisic acid (ABA) has been ass...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2019.1637874
更新日期:2020-01-01 00:00:00
abstract::A new thiodiketopiperzaine, tedanizaine A (1), together with six known ones, were isolated from the marine sponge Tedania sp. Their structures were determined by spectroscopic analyses. The absolute configuration of 1 was established by ECD calculation. Compound 1 was the second example of thiodiketopiperazine bearing...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2018.1550770
更新日期:2020-04-01 00:00:00
abstract::In this work, we report a rapid and convenient HPLC-UV-DAD method for the isolation of δ-T3 on semi-preparative scale from two different vitamin E rich processed, commercially available products obtained from the fruits of Elaeis guineensis Jacq. (oil palm) and from the seeds of Bixa orellana L. (achiote tree). Chroma...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2017.1320793
更新日期:2018-05-01 00:00:00
abstract::Due to the increasing emergence of resistance of bacterial pathogens to current antibiotics, we have examined the marine fungi present in sea sediments obtained 200 m offshore to discover new antibacterial compounds active against multidrug-resistant bacteria. One strain, identified as Emericellopsis minima, was isola...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2017.1344655
更新日期:2018-06-01 00:00:00
abstract::This study aimed at evaluating the impact of environmental factors on the accumulation of various components in Hedera helix L. folium collected from different European countries. The obtained results of studied samples showed that the antioxidant capacities were in the range of 0.027 to 0.688 mg/g. Contents of active...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2020.1843029
更新日期:2020-11-04 00:00:00
abstract::Three new neolignan derivatives (1-3), together with three known isolariciresinol derivatives (4-6) were isolated from Selaginella picta. Their structures were elucidated by spectroscopic methods (1D/2D NMR, HRESIMS and CD). All isolated compounds were assayed on the neuroprotective activity against the injury of HT-2...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2018.1560284
更新日期:2020-05-01 00:00:00
abstract::A new γ-pyrone derivative, acrepyrone A (1), and three known sorbicillinoids, trichodimerol (2), dihydrotrichodimerol (3) and tetrahydrotrichodimerol (4) were isolated from an endophytic fungus, Acremonium citrinum SS-g13, harboured in the roots of the Chinese medicinal plant Fructus mori. Their structures were determ...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2018.1548462
更新日期:2020-04-01 00:00:00
abstract::Jatropha mutabilis (Pohl) Baill is an endemic species of the Caatinga biome, little studied in terms of chemical composition. The objective of this work was to develop an analytical methodology to quantify vitexin in the ethanolic extract of J. mutabilis and to evaluate the expectorant and antitussive activities in mi...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2020.1837807
更新日期:2020-10-30 00:00:00
abstract::Cumin (Cuminum cyminum) is an annual plant from Apiaceae family that is cultivated in Iran as landraces. The most important chemical composition of the cumin essential oil was cuminaldehyde. In this research, the effect of different landraces and growth regulators was evaluated on callus induction, and best callus was...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2016.1272105
更新日期:2017-09-01 00:00:00
abstract::This study was focused on in vitro cytotoxicity screening of the raspberry seeds methanol extract towards a number of cancer cell lines of human origin. The tested extract at the preferred concentrations (IC50 <30 µg/mL) inhibited only the growth of the lung cancer A-549 cells (IC50 = 14.07 ± 0.96 µg/mL). At the same ...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2019.1666391
更新日期:2019-09-17 00:00:00
abstract::Artemisia herba-alba is widely used in traditional medicines for the treatment of several diseases. From the aerial parts organic extract of A. herba-alba, two new compounds, 1,3,8-trihydroxyeudesm-4-en-7α,11βH-12,6α-olide (1) and 5-β-D-glucopyranosyloxy-7-methoxy-6H-benzopyran-2-one (2), respectively, togethe...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2019.1647430
更新日期:2019-07-31 00:00:00
abstract::Propolis is a honeybee product that has been used since ancient times because of its therapeutic effects. It can be used in the development of alternative therapies for the treatment of many diseases, and because propolis shows antibacterial action, this work was carried out in order to investigate a possible synergis...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786411003754355
更新日期:2012-01-01 00:00:00
abstract::The objective of this work was to produce and characterise nanoemulsions containing tucumã extract and to evaluate the performance of the nanostructure and the free compound regarding antitumor activity, cytotoxicity, and oxidative metabolism in NB4/APL cells. The nanoemulsions showed adequate physicochemical characte...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2020.1862830
更新日期:2020-12-24 00:00:00
abstract::This paper aims to investigate, for the first time, physicochemical characteristics and antioxidant capacity of Psidium myrtoides ripe and unripe fruit. In addition, essential oil was extracted from fresh leaves (PM-EO) collected in dry and rainy seasons to investigate the influence of seasonality and, after that, to ...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2020.1844689
更新日期:2020-11-09 00:00:00
abstract::The aim of this study was to explore the extract/fractions and compounds of Diospyros lotus against various Gram-positive and Gram-negative bacteria strain. The results showed marked susceptibility of extract and its fractions against test pathogens. Among them, chloroform fraction was most dominant and effective agai...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2015.1013957
更新日期:2016-01-01 00:00:00
abstract::ABTRACT This study aims to design and synthesize a series of N-Acyl-N-(m-fluoro- benzyl)-6- amino-coumarins through the principle of active substructure stitching, which are based on the core structure of N-(m-fluoro-benzyl)-6-amino-coumarin. The structures of target compounds e1-e25 have been characterized by 1H NMR,...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2020.1806268
更新日期:2020-08-13 00:00:00
abstract::A novel Amaryllidaceae alkaloid, 6-O-methylkrigeine, has been isolated from Nerine huttoniae and the configuration was elucidated by 1-D and 2-D (1)H-NMR, (13)C-NMR, HRMS and optical rotation. ...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2010.533668
更新日期:2012-01-01 00:00:00
abstract::The aim of this study was to investigate mercury accumulation in some species, caught in Mediterranean Sea, in the period between May and December 2015, and to compare it to the presence of Anisakis parasites. The samples were examined by direct mercury analyzer (DMA-80) for their Hg levels. The metal concentration wa...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2016.1230119
更新日期:2017-05-01 00:00:00