Biologically active metabolites from fungi, 19: new isocoumarins and highly substituted benzoic acids from the endophytic fungus, Scytalidium sp.

abstract：:Cyanamide (NH(2)CN) has recently been isolated as a plant growth inhibitor from Vicia villosa, which is the first discovery of cyanamide from natural sources. To reveal the presence of the biosynthesized cyanamide in plants, 3.4 mM potassium ((15)N)nitrate was administered to 15- to 35-day-old plants of V. villosa, fr...

journal_title：Natural product research

authors： Kamo T,Kato K,Hiradate S,Nakajima E,Fujii Y,Hirota M

更新日期：2006-05-10 00:00:00

abstract：:We report the first analysis in absolute, and in particular, concerning the phytochemical pattern, about an endemic Italian species, Ajuga tenorei C. Presl. The analysis, performed by means of techniques such as Column Chromatography and NMR spectroscopy and Mass spectrometry, led to the isolation and the identificati...

journal_title：Natural product research

authors： Frezza C,Venditti A,Di Cecco M,Ciaschetti G,Serafini M,Bianco A

更新日期：2017-01-01 00:00:00

abstract：:This study is part of a wider investigation aimed to sustain the economical value of the by-products generated by the Citrus industry. In particular, the protected geographic indication (PGI) red orange of sicily (known as blood orange) has been analysed by HPLC and by the enzymatic AOAC method. All the by-products co...

journal_title：Natural product research

authors： Russo M,Bonaccorsi IL,Arigò A,Cacciola F,De Gara L,Dugo P,Mondello L

更新日期：2019-11-29 00:00:00

abstract：:The biological properties of medicinal plants have been documented worldwide for many centuries. We aimed to evaluate interactions between crude extracts from Psidium guajava, Zingiber officinale, Cymbopogon citratus, Caryophyllus aromaticus, Mikania glomerata and Allium sativum samples and antimicrobial drugs against...

journal_title：Natural product research

authors： Ushimaru PI,Barbosa LN,Fernandes AA,Di Stasi LC,Fernandes A Jr

更新日期：2012-01-01 00:00:00

abstract：:The study examined the radioprotective activity of an aqueous extract from Pleurotus ostreatus mycelium administered to Balb/c mice. Male mice were whole-body irradiated on day 0 ((60)Co, at 0.43 Gy/min) and divided into two groups. The extract was administered intraperitoneally to one group (100 mg/kg) on days - 10 t...

journal_title：Natural product research

authors： Llauradó G,Morris HJ,Tamayo V,Lebeque Y,Beltrán Y,Marcos J,Moukha S,Creppy EE,Bermúdez RC

更新日期：2015-01-01 00:00:00

abstract：:In this study, the efficiency of nanoporous aluminium wires as fibres for headspace solid-phase microextraction (HS-SPME) of volatile compounds from Lippia citriodora was investigated and compared with two anodised methods. The prepared fibres are durable with very good chemical and thermal stability which can be coup...

journal_title：Natural product research

authors： Nemati Kharajuo M,Piryaei M,Babashpour Asl M,Abolghasemi MM

更新日期：2017-02-01 00:00:00

abstract：:The essential oil composition of the aerial parts of Nepeta erecta Benth. (Family: Lamiaceae) from Uttarakhand, India was analysed by capillary gas chromatography (GC) and gas chromatography-mass spectrometry (GC-MS). A total of 34 constituents were identified representing 94.6% of the oil composition. Oxygenated mono...

journal_title：Natural product research

authors： Bisht DS,Joshi SC,Padalia RC,Mathela CS

更新日期：2012-01-01 00:00:00

abstract：:A new germacrenolide (1) and fourteen known terpenoids (2-15) were isolated from the barks of Magnolia maudiae (Dunn) Figlar (Magnoliaceae). The structure of (7αH,11βH)-2α,8α-dihydroxy-4α,5β-epoxy-germacr-1(10)-en-6α,12-olide (1) was elucidated by physical and spectroscopic data analysis, including 1D, 2D NMR and HR-E...

journal_title：Natural product research

authors： Xianjin S,Sha S,Qi M,Zhang Z,Yang Y,Wu H,Li L,Wang W,Huang A

更新日期：2018-07-01 00:00:00

abstract：:This work is an attempt to explore the anti-spermatogenic activity of Pistia stratiotes and to investigate it as a male contraceptive. The prepared extracts were screened for the presence of alkaloids, glycosides, steroids, flavonoids, saponin and phenolic compounds. To assess the anti-spermatogenic activity, mice wer...

journal_title：Natural product research

authors： Singh K,Dubey BK,Tripathi AC,Singh AP,Saraf SK

更新日期：2014-01-01 00:00:00

abstract：:A new bisabolane-type sesquiterpenoid, turmerone Q (1), along with six known compounds (2-7), were isolated from the rhizomes of Curcuma longa L. The structural elucidation of the new compound was conducted using 1H NMR, 13C NMR, HSQC, HMBC and NOESY spectroscopic analyses. The absolute configuration of 1 was elucidat...

journal_title：Natural product research

authors： Yuan T,Zhang C,Qiu C,Xia G,Wang F,Lin B,Li H,Chen L

更新日期：2018-08-01 00:00:00

abstract：:Two flavonoid glycosides containing acetylated allose, and two iridoid glucosides were obtained from a EtOH extract of Stachys corsica, an endemic plant of Sardinia and Corsica. All the compounds have previously been isolated from other species of Stachys. ...

journal_title：Natural product research

authors： Serrilli AM,Ramunno A,Piccioni F,Serafini M,Ballero M

更新日期：2005-09-01 00:00:00

abstract：:A new protopine alkaloid, protomexicine and a new isoflavonoid, mexitin, together with 8-methoxydihydrosanguinarine, 13-oxoprotopine, rutin and quercetrin have been isolated from the aerial part of the methanolic extract of Argemone mexicana. The structures of these compounds have been established by various spectral ...

journal_title：Natural product research

authors： Singh S,Pandey VB,Singh TD

更新日期：2012-01-01 00:00:00

abstract：:A new propanamide analogue (1), along with one known alkaloid (2) and four known diketopiperazines (3-6), was isolated from a cultured broth of the actinomycete Streptomyces sp. Q24 that was obtained from a sample of mangrove soil. The structures of these isolates were characterised as 3-acetylamino-N-2-thienyl-propan...

journal_title：Natural product research

authors： Ye X,Chai W,Lian XY,Zhang Z

更新日期：2017-06-01 00:00:00

abstract：:A high performance liquid chromatography-time-of-flight-mass spectrometry (HPLC-TOF-MS) method was developed for analysing the chemical constituents in Hedyotis diffusa, which is widely used as a traditional Chinese medicine (TCM) in the field of cancer treatment. The compounds were identified either by comparing the ...

journal_title：Natural product research

authors： Wang X,Cheng W,Yao X,Guo X

更新日期：2012-01-01 00:00:00

abstract：:Three biflavonoid glycosides, named carinoside B, C and D (1, 2 and 3, respectively), were isolated from the n-BuOH crude extract of the aerial part of Lomatogonium carinthiacum (Wulfen) Rchb (L. carinthiacum). The structures of 1, 2 and 3 were elucidated by spectroscopic methods, including UV, IR, HR-ESI-MS and exten...

journal_title：Natural product research

authors： Bao B,Wang Q,Wu X,Tai W

更新日期：2015-01-01 00:00:00

abstract：:Marsdenia tinctoria is an indigo producing plant commonly found in Borneo, Malaysia. In this present study, one new flavone kapitone (1) and three known compounds, that is 3,2'-dihydroxyflavone (2), 1-methylcyclobutene (3) and dimethyl isatoate (4) were isolated from the Malaysia Borneo M. tinctoria R. Br. (Apocynacea...

journal_title：Natural product research

authors： Mohd Nasuha NA,Choo YM

更新日期：2016-07-01 00:00:00

abstract：:The current study introduces a new idea of utilising several bio/chemoinformatics tools in comparing two bio-similar natural molecules viz. curcumin and bisdemethoxycurcumin (BDMC) in order to select a potential nose-to-brain remedy for Alzheimer disease. The comparison comprised several bio/chemo informatics tools. I...

journal_title：Natural product research

authors： Hathout RM,El-Ahmady SH,Metwally AA

更新日期：2018-12-01 00:00:00

abstract：:A short total synthesis of natural isocarbostyril ruprechstyril (3-n-pentyl-6-methoxy-8-hydroxy-1(2H)-isoquinolinone) isolated from Ruprechtia tangarana is reported. 6,8-Dimethoxy-3-pentylisocoumarin obtained by condensation of 3,5-dimethoxyhomophthalic anhydride with hexanoyl chloride was smoothly converted to O-meth...

journal_title：Natural product research

authors： Saeed A

更新日期：2013-01-01 00:00:00

abstract：:From the fruit of Pandanus tectorius Parkinson ex Du Roi, one new (1) and six known aldehyde compounds (2-7) were isolated by various chromatography methods. Based on their spectroscopic data, these compounds were identified as (Z)-4-hydroxy-3-(4-hydroxy-3-methylbut-2-en-1-yl) benzaldehyde (1), p-hydroxybenzaldehyde (...

journal_title：Natural product research

authors： Mai DT,Le TD,Nguyen TP,Phan NM,Nguyen HA,Nguyen TT,Tran le Q

更新日期：2015-01-01 00:00:00

abstract：:Investigations were performed on the determination of the main components in Berchemia lineata (L.) DC. (BL) and its metabolism with human liver microsomes (HLM). A total of 35 compounds were detected in BL extracts and 25 of them including 6 naphthopyrones, 10 flavonoids, 2 phenolic acids, 2 phenols, 4 fatty acids an...

journal_title：Natural product research

authors： Jiang X,Chen S,Guo Z,Gu D,Liang X

更新日期：2021-02-01 00:00:00

abstract：:A new protein detector of 2,4,6-trinitrophenol (TNP, picric acid) is concisely reported herein for the first time. In brief, the gene of a specific scFv fragment, namely 3.5, was fused separately with the gene of β-lactamase and, subsequently, expressed in the periplasmic space of Escherichia coli, affording in such a...

journal_title：Natural product research

authors： Simonovic M,Mix T,Glumac M,Pejin B

更新日期：2020-12-18 00:00:00

abstract：:Three species of the genus Homalium - e.g. Homalium nepalense, Homalium tomentosum and Homalium zeylanicum (Flacourtiaceae) - are recorded in India which are confined to the Eastern Ghat hill ranges. While H. zeylanicum is the IUCN red-listed medium-sized tree, the other two are endangered species of medicinal signifi...

journal_title：Natural product research

authors： Mahapatra AK,Pani SS,Sahoo AK

更新日期：2015-01-01 00:00:00

abstract：:The composition and antibacterial activity of the essential oil of the aerial flowering parts of Nepeta hormozganica Jamzad have been studied. Analysis of the oil was conducted by GC-FID and GC-MS. Thirty-two components were characterized accounting for 99.4% of the total oil. Oxygenated monoterpenes (87.5%) were foun...

journal_title：Natural product research

authors： Sonboli A,Saadat MH,Arman M,Kanani MR

更新日期：2017-12-01 00:00:00

abstract：:Three allylbenzenes from Asiasarum heterotropoides, methyleugenol (1), elemicin (2) and gamma-asaron (3) showed suppressive effects on umu gene expression of the SOS response in the Salmonella typhimurium OY1001/1A2 umu test against the mutagen 2-amino-3,4-dimethylimidazo[4,5-f ]quinoline (MeIQ). Gene expression was s...

journal_title：Natural product research

authors： Miyazawa M,Kohno G,Okuno Y,Oda Y

更新日期：2006-06-01 00:00:00

abstract：:A new phenolic glycoside, 6-O-(4'-hydroxy-3',5'-dimethoxybenzoyl)-d-glucopyranose (4), and nine known compounds (1-3 and 5-10) were isolated from Juglans mandshurica Maxim. Compound structures were elucidated by NMR, HR-ESI-MS and acid hydrolysis. Compounds 5 and 6 are reported from this genus for the first time. Amon...

journal_title：Natural product research

authors： Yao D,Jin M,Zhang C,Luo J,Li R,Zheng M,Cui J,Li G

更新日期：2014-01-01 00:00:00

abstract：:Artemisia annua L. is an annual Eurasian desert-steppe plant. The composition of essential oils found in Artemisia annua from Russian (Buryatian) flora was analyzed in this work using gas chromatography mass-spectrometry method. Artemisia ketone, β-selinene, caryophyllene, caryophyllene oxide, germacrene D were the ma...

journal_title：Natural product research

authors： Zhigzhitzhapova SV,Dylenova EP,Gulyaev SM,Randalova TE,Taraskin VV,Tykheev ZA,Radnaeva LD

更新日期：2020-09-01 00:00:00

abstract：:Phytochemical investigation of Strychnos nitida has led to the isolation of three new racemic pyridocarbazole alkaloids, (±)-stritidas A-C (1-3) and three known monoterpenoid indole alkaloids (4-6). Compounds 2 and 3 represent the first examples of pyridocarbazole alkaloids featuring an N-2-hydroxyethyl moiety. Their ...

journal_title：Natural product research

authors： Li W,Tang GH,Chen L,Tang YQ,Xu YK,Liu B,Yin S

更新日期：2018-07-01 00:00:00

abstract：:A new cholestane-type steroidal glycoside, solamyriaside A (1), was isolated from the fruits of Solanum myriacanthum Dunal (Solanaceae), along with two known steroidal glycosides, namely, solaviaside A (2) and aculeatiside A (3), and three known steroidal alkaloid glycosides, namely, solamargine (4), khasianine (5) an...

journal_title：Natural product research

authors： Ono M,Shimode M,Tsutsumi S,Yasuda S,Okawa M,Kinjo J,Miyashita H,Ikeda T,Yoshimitsu H,Nohara T

更新日期：2020-06-19 00:00:00

abstract：:The chemical constituents identified in the essential oils hydrodistilled from the leaves of Amomum gagnepainii T.L.Wu, K.Larsen and Turland and Amomum repoense Pierre ex Gagnep (Zingiberaceae) of Vietnam origin are reported. The chemical analyses were performed by means of gas chromatography-flame ionisation detector...

journal_title：Natural product research

authors： Huong LT,Hung NV,Chung MV,Dai DN,Ogunwande IA

更新日期：2018-02-01 00:00:00

abstract：:Phytochemical investigations on Phyllanthus emblica have resulted in the isolation of the two new flavonoids, kaempferol-3-O-alpha-L-(6''-methyl)-rhamnopyranoside (1) and kaempferol-3-O-alpha-L-(6''-ethyl)-rhamnopyranoside (2). Their structures were determined on the basis of extensive spectroscopic studies including ...

journal_title：Natural product research

authors： Habib-ur-Rehman,Yasin KA,Choudhary MA,Khaliq N,Atta-ur-Rahman,Choudhary MI,Malik S

更新日期：2007-07-20 00:00:00