Abstract:
:The biological properties of medicinal plants have been documented worldwide for many centuries. We aimed to evaluate interactions between crude extracts from Psidium guajava, Zingiber officinale, Cymbopogon citratus, Caryophyllus aromaticus, Mikania glomerata and Allium sativum samples and antimicrobial drugs against Escherichia coli strains. The susceptibility test performed was disc diffusion, and crude extracts were diluted (%v/v) into Müller-Hinton agar (MHA) at one quarter of the minimal inhibitory concentration for 90% (MIC(90%)) of E. coli strains found previously. Synergistic interactions were observed between C. citratus and polymyxin, and A. sativum extracts and gentamicin. The crude A. sativum extract was the only one that did not show any antagonism with the antimicrobial drugs. The results thus showed the potential use of these medicinal plants against E. coli strains, although antagonism with antimicrobial drugs is a negative aspect in the combined therapy of infectious diseases caused by E. coli.
journal_name
Nat Prod Resjournal_title
Natural product researchauthors
Ushimaru PI,Barbosa LN,Fernandes AA,Di Stasi LC,Fernandes A Jrdoi
10.1080/14786419.2011.568943subject
Has Abstractpub_date
2012-01-01 00:00:00pages
1553-7issue
16eissn
1478-6419issn
1478-6427journal_volume
26pub_type
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