Antibacterial activity and composition of the essential oil of Nepeta hormozganica Jamzad from Iran.

Abstract:

:The composition and antibacterial activity of the essential oil of the aerial flowering parts of Nepeta hormozganica Jamzad have been studied. Analysis of the oil was conducted by GC-FID and GC-MS. Thirty-two components were characterized accounting for 99.4% of the total oil. Oxygenated monoterpenes (87.5%) were found to be the predominant group of compounds, of which 18-cineole (65.0%) and 4aα-7α-7aβ-nepetalactone (13.0%) were the main constituents. The antibacterial activity of the essential oil and its main constituents showed that all of the tested microorganisms were highly inhibited by the essential oil with inhibition zones ranged from 12 to 24 mm. The most sensitive bacteria were Staphylococcus aureus and Staphylococcus epidermidis with the lowest MIC values of 0.3 and 0.6 mg/mL, respectively. Considering sensitivity screening it is conceivable that the activity of the oil from N. hormozganica could be attributed mainly to the synergistic property of 18-cineole and nepetalactone.

journal_name

Nat Prod Res

journal_title

Natural product research

authors

Sonboli A,Saadat MH,Arman M,Kanani MR

doi

10.1080/14786419.2017.1295237

subject

Has Abstract

pub_date

2017-12-01 00:00:00

pages

2806-2809

issue

23

eissn

1478-6419

issn

1478-6427

journal_volume

31

pub_type

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