Analysis of peripheral T cells and the CC chemokine receptor (CCR5) delta32 polymorphism in prostate cancer patients treated with carboxymethyl-glucan (CM-G).

abstract：:Both enantiomers of the polyketide-derived lactone citreofuran (4) have been prepared. The enantiopure building blocks were obtained on a chemoenzymatic route ((S)-6) and by a chiral pool synthesis ((R)-6). The crucial step in the synthesis, a macrolactonization, was accomplished under Mitsunobu conditions. ...

journal_title：Natural product research

authors： Bracher F,Schulte B

更新日期：2003-08-01 00:00:00

abstract：:Eurya acuminata DC and Croton caudatus Gieseler are two ethno-medicinal plants used by Kuki community of North East India. From these plants, we have characterized fifteen phytochemicals (1-15) by extensive use of chromatographic and spectroscopic methods. They were also tested for in vitro cytotoxic effects against A...

journal_title：Natural product research

authors： Neipihoi,Narzary B,Saikia S,Saikia S,Tamuli KJ,Sahoo RK,Dutta D,Bordoloi M

更新日期：2020-09-16 00:00:00

abstract：:Investigation of the roots of Lotus polyphyllos Clarke resulted in the isolation of two new isoflavone derivatives; 4'-O-methylerythrinin C (3) and 4'-O-methyl-2''-hydroxydihydroalpinumisoflavone (4). In addition, the three known isoflavone derivatives 4'-O-methylalpinumisoflavone (1) lupinalbin F (5), 4',7-dimethoxy-...

journal_title：Natural product research

authors： Abdel-Kader MS,Amer ME,Tang S,Kingston DG

更新日期：2006-08-01 00:00:00

abstract：:The dichloromethane extracts of the leaves, stem bark, bark and the roots of the three species of the primitive endemic genus Hortonia, H. angustifolia, H. floribunda and H. ovalifolia, collected from nine geographical locations ranging from lower elevations (84-420 m) to higher (2000 m) showed comparable HPLC profile...

journal_title：Natural product research

authors： Ratnayake R,Ratnayake Bandara BM,Wijesundara S,Macleod JK,Simmonds P,Karunaratne V

更新日期：2008-01-01 00:00:00

abstract：:A new dimeric secoiridoids derivative, named japonicaside E, together with six known compounds were isolated from the flower buds of Lonicera japonica. The structures of these compounds were elucidated by the analyses of mass spectrometry and NMR spectroscopy. All compounds were evaluated for anti-inflammatory activit...

journal_title：Natural product research

authors： Ge W,Li HB,Fang H,Yang B,Huang WZ,Xiao W,Wang ZZ

更新日期：2019-01-01 00:00:00

abstract：:Two diketopiperazines were isolated from a culture of the marine-derived actinomycete Streptomyces sp. ZZ446. Their structures were elucidated as maculosin (1) and maculosin-O-α-L-rhamnopyranoside (2) based on their NMR and HRESIMS data, specific rotation, and chemical degradation. Maculosin-O-α-L-rhamnopyranoside (2)...

journal_title：Natural product research

authors： Chen S,Zhang D,Chen M,Zhang Z,Lian XY

更新日期：2020-04-01 00:00:00

abstract：:To date, despite extensive investigations, full understanding of the endocannabinoid system remains elusive; in particular, anandamide cellular uptake is a current controversial topic. An iodo-arylazido probe was synthesized from commercially available azelaic acid monomethyl ester, in order to shed light on the anand...

journal_title：Natural product research

authors： Balas L,Hellal M,Rossi JC,Durand T

更新日期：2005-06-01 00:00:00

abstract：:A new flavonol glycoside named Sabiapside A (1), along with four known compounds, quercetin-3-O-gentiobioside (2), camellianoside (3), isobariclisin-3-O- rutinoside (4), tsubakioside A (5), was isolated from Sabia parviflora. Their structures were elucidated by extensive spectroscopic analysis including MS, UV, IR and...

journal_title：Natural product research

authors： Sun Q,Pan G,Xu W,Lu X,Bai C,Liu M,Chen Y

更新日期：2019-10-29 00:00:00

abstract：:Phorbol esters (PEs) are diterpenes present in Jatropha curcas L. seeds and have a myriad of biological activities. Since PEs are toxic, they are considered to be futile in Jatropha-based biodiesel production chain. In the present study, the extracted PEs from Jatropha oil were used as a starting material to synthesis...

journal_title：Natural product research

authors： Devappa RK,Malakar CC,Makkar HP,Becker K

更新日期：2013-01-01 00:00:00

abstract：:Nine compounds were isolated from Nocardia sp. YIM 64630, and their structures were elucidated as 5'-O-acetyl-2'-deoxyuridine (1), 22E,24R-5α,6α-epoxyergosta-8(14),22-diene-3β,7α-diol (2), 22E,24R-5α,6α-epoxyergosta-8,22-diene-3β,7α-diol (3), 22E,24R-ergosta-7,22-diene-3β,5α,6β-triol (4), 5α,8α-epidioxyergosta-6,22-di...

journal_title：Natural product research

authors： Li W,Yang X,Yang Y,Qin S,Li Q,Zhao L,Ding Z

更新日期：2015-01-01 00:00:00

abstract：:One known bis-indole alkaloid-voacamine was isolated from Voacanga africana Stapf and Surface Plasmon Resonance imaging (SPRi) exprement showed that this alkaloid could be combine with Protein Tyrosine Phosphatase1B (PTP1B). Then the PTP1B activity inhibition experiment display that the compound showed an outstanding ...

journal_title：Natural product research

authors： Wang YQ,Li HX,Liu XC,Zhao JS,Liu RQ,Huai WY,Ding WJ,Zhang TE,Deng Y

更新日期：2019-12-01 00:00:00

abstract：:A new protostane-type triterpenoid bearing an oxetane ring in the side-chain, named alisol W (1), has been obtained from the dried rhizome of Alisma plantago-aquatica subsp. orientale. The structure and absolute configuration of compound 1 was determined from extensive spectroscopic analysis. In addition, the vasorela...

journal_title：Natural product research

authors： Li HM,Liu D,Dai WF,Chen XQ,Li RT

更新日期：2019-11-01 00:00:00

abstract：:Continued investigation of the marine alga Laurencia claviformis has led to the isolation of pacifenol, a halogenated sesquiterpene as the major metabolite. The microbial transformation of pacifenol is reported. It was cultivated with a marine strain of Penicillium brevicompactum yielding a new compound. The structure...

journal_title：Natural product research

authors： San-Martín A,Rovirosa J,Astudillo L,Sepúlveda B,Ruiz D,San-Martín C

更新日期：2008-12-01 00:00:00

abstract：:Three anthraquinones, Cdc25B phosphatase inhibitors, were isolated from the methanolic extract of the roots of Polygonum multiflorum Thunb. (Polygonaceae). Anthraquinones, physcion (1), emodin (2), and questin (3), inhibited the enzymatic activity of Cdc25B phosphatase with IC(50) values of 62.5, 30, and 34 microg mL(...

journal_title：Natural product research

authors： Choi SG,Kim J,Sung ND,Son KH,Cheon HG,Kim KR,Kwon BM

更新日期：2007-05-20 00:00:00

abstract：:The hexane and ethanol extracts from Himatanthus bracteatus (Apocynaceae) stems were evaluated for antiviral activity against Zika virus, yellow fever virus and dengue virus 2 and for cytotoxicity in Vero cells by MTT assay. The ethanol extract showed good antiviral activity against the three viruses with selective in...

journal_title：Natural product research

authors： da Silva ML,Stehmann JR,Serafim MSM,Vale VV,Gontijo DC,Brandão GC,Kroon EG,de Oliveira AB

更新日期：2019-11-20 00:00:00

abstract：:Two new cycloartane-type glycosides, caspicuside I and caspicuside II, were isolated along with two known saponins, cycloastragenol and astragaloside IV, from the roots of Astragalus caspicus. As the aglycon group, caspicuside I possesses 3beta,6alpha,16beta,(24S),25-pentahydroxycycloartane (cyclocanthagenol), while c...

journal_title：Natural product research

authors： Fathiazad F,Khosropanah MK,Movafeghi A

更新日期：2010-07-01 00:00:00

abstract：:A new compound decomposed from ginkgolide B(GB) is discovered and identified by MS and UV spectrum. It is the dehydrate of GB, which was named as ginkgolide K before. Differently, it cannot exist independently, but only in equilibrium with GB. It is found first time that 3-hydroxy is active in some solvent. ...

journal_title：Natural product research

authors： Yuan C,Pan J,Hu X

更新日期：2008-01-01 00:00:00

abstract：:Jatropha mutabilis (Pohl) Baill is an endemic species of the Caatinga biome, little studied in terms of chemical composition. The objective of this work was to develop an analytical methodology to quantify vitexin in the ethanolic extract of J. mutabilis and to evaluate the expectorant and antitussive activities in mi...

journal_title：Natural product research

authors： Costa EC,Menezes PMN,Silva FS,Ribeiro LAA,Rolim LA,Araújo ECDC,Nunes XP

更新日期：2020-10-30 00:00:00

abstract：:One new furofuran lignan 2-methoxy-9β-hydroxydiasesamin (1), and four analogues (2-5), together with eight alkaloids (6-13), were isolated from the ethanol extract of the aerial part of Clinacanthus nutans. Their structures were elucidated by the detailed analysis of comprehensive spectroscopic data. All the compounds...

journal_title：Natural product research

authors： Diao HZ,Chen WH,Cao J,Shao TM,Song XP,Han CR

更新日期：2019-05-01 00:00:00

abstract：:The search for bioactive natural products from the rhizomes of Paris polyphylla (Trilliaceae) has resulted in the isolation of four known constituents, 1,5-dihydroxy-7-methoxy-3-methylanthraquinone (1), diosgenin-3-O-[alpha-L-rhamnopyranosyl-(1 --> 3)-beta-D-glucopyranoside] (2), diosgenin-3-O-[alpha-L-rhamnopyranosyl...

journal_title：Natural product research

authors： Devkota KP,Khan MT,Ranjit R,Lannang AM,Samreen,Choudhary MI

更新日期：2007-04-01 00:00:00

abstract：:A new resin glycoside, named calysolin XVIII (1), was isolated from the leaves, stems and roots of Calystegia soldanella Roem. et Schult. (Convolvulaceae). The structure of 1 was defined as 11S-jalapinolic acid 11-O-β-d-glucopyranosyl-(1 → 3)-O-(2-O-2S-methylbutyryl,4-O-3-hydroxy-2-methylenebutyryl)-α-l-rhamnopyranosy...

journal_title：Natural product research

authors： Ono M,Kanemaru Y,Yasuda S,Okawa M,Kinjo J,Miyashita H,Yokomizo K,Yoshimitsu H,Nohara T

更新日期：2017-11-01 00:00:00

abstract：:Lavandin (Lavandula × intermedia Emeric ex Loiseleur) essential oils (EOs), from Abrial, Super and Grosso cultivars, cultivated and extracted in the South East of Spain, were analysed by using GC/MS to determine their composition, in both relative (peak area) and absolute (using standard curves) concentrations. Linalo...

journal_title：Natural product research

authors： Carrasco A,Martinez-Gutierrez R,Tomas V,Tudela J

更新日期：2016-01-01 00:00:00

abstract：:Loliolide content was determined in 13 marine algae including red, brown and green algae collected from the Black Sea, the Dardanelles and the Aegean Sea. Identification and quantification were performed by gas chromatography-mass spectrometry. The loliolide content in green alga is 1.76 microg g(-1), ranges from 0.14...

journal_title：Natural product research

authors： Percot A,Yalcin A,Aysel V,Erduğan H,Dural B,Güven KC

更新日期：2009-01-01 00:00:00

abstract：:The aim of the study was comparing the chemical composition of the essential oils from five varieties of lavender (Lavandula angustifolia L.), and its biological activity against two pathogenic bacteria, Staphylococcus aureus and Pseudomonas aeruginosa. In the comparison we included the following varieties: 'Munstead'...

journal_title：Natural product research

authors： Adaszyńska M,Swarcewicz M,Dzięcioł M,Dobrowolska A

更新日期：2013-01-01 00:00:00

abstract：:Investigations were performed on the determination of the main components in Berchemia lineata (L.) DC. (BL) and its metabolism with human liver microsomes (HLM). A total of 35 compounds were detected in BL extracts and 25 of them including 6 naphthopyrones, 10 flavonoids, 2 phenolic acids, 2 phenols, 4 fatty acids an...

journal_title：Natural product research

authors： Jiang X,Chen S,Guo Z,Gu D,Liang X

更新日期：2021-02-01 00:00:00

abstract：:(+) Benzomalvins E (1) and (-) Benzomalvins E (2), a pair of epimeric derivatives, together with three known benzomalvins (3-5), were isolated from solid cultures of a interrhizospheric fungus Penicillium sp. SYPF 8411. The planar structure of (+) Benzomalvins E (1) has been previously reported. While, the absolute co...

journal_title：Natural product research

authors： Feng QM,Feng Y,Zhang TY,Wang HF,Zhang MY,Wu YY,Chen G,Zhang YX,Pei YH

更新日期：2020-07-01 00:00:00

abstract：:Machaerium, in the family Fabaceae, predominantly is a genus of a Neotropical distribution of trees, shrubs, and lianas occurring from southern Mexico to Brazil and northern Argentina and as far as South America. Several Machaerium species are widely used in traditional medicine and are considered to have multiple med...

journal_title：Natural product research

authors： Amen YM,Marzouk AM,Zaghloul MG,Afifi MS

更新日期：2015-01-01 00:00:00

abstract：:The chloroformic extract of the aerial parts of Ferula behboudiana (Umbelliferae) afforded four new polysulphane derivatives: 1-sec-butyl-2-[(E)-3-(methylthio)prop-1-enyl]disulphane (1), 1-sec-butyl-2-[(Z)-3-(methylthio)prop-1-enyl]disulphane (2), 1-[(E)-3-(methylthio)prop-1-enyl)-2-(1-(methylthio)propyl]disulphane (3...

journal_title：Natural product research

authors： Yousefi M,Mohammadi M,Habibi Z,Shafiee A

更新日期：2010-09-01 00:00:00

abstract：:The purpose of this study is the determination of chemical composition and antioxidant activity of essential oils (EOs) from Saussurea costus (Falc.) Lipsch. Roots have been collected on December of the first plant year (IY) and in April, August and December of the third plant year (I, 6B, D7). A GC analysis was carri...

journal_title：Natural product research

authors： Benedetto C,D'Auria M,Mecca M,Prasad P,Singh P,Singh S,Sinisgalli C,Milella L

更新日期：2019-08-01 00:00:00

abstract：:Chronic neuroinflammation is a key component of many neurodegenerative disorders. Chronic activation of this process produces pro-inflammatory cytokines, prostaglandins and reactive oxygen species that induce brain injury and neuronal dysfunction. Agave species contain saponins, compounds with anti-inflammatory activi...

journal_title：Natural product research

authors： Herrera-Ruiz M,Jiménez-Ferrer E,Tortoriello J,Zamilpa A,Alegría-Herrera E,Jiménez-Aparicio AR,Arenas-Ocampo ML,Martínez-Duncker I,Monterrosas-Brisson N

更新日期：2019-05-14 00:00:00