Anthraquinones, Cdc25B phosphatase inhibitors, isolated from the roots of Polygonum multiflorum Thunb.

abstract：:An activity-guided isolation and purification process was used to identify the l,l-diphenyl-2-picrylhydrazyl (DPPH) free radical-scavenging components of the food plant (Terminalia arjuna) of Antheraea mylitta. Dry leaves of T. arjuna were extracted with different solvents and tested for their antioxidant activity aga...

journal_title：Natural product research

authors： Singh PP,Chauhan SM

更新日期：2014-01-01 00:00:00

abstract：:Two new xanthone derivatives, penixanthones A (1) and B (2), together with three known compounds, aspenicillide (3), 1,5-dihydroxy-3-methoxy-7-methyl-anthracene-9,10-dione (4) and 1,2-indandiol (5), were isolated from the ethyl acetate extract of a culture of the fungus Penicillium sp. SYFz-1, which was separated from...

journal_title：Natural product research

authors： Tao H,Wei X,Lin X,Zhou X,Dong J,Yang B

更新日期：2017-10-01 00:00:00

abstract：:A new ent-kaurane diterpenoid, lophanthodin G (1) and one known abietanoid, 6alpha-hydroxyferruginol (2), were isolated from the leaves of Isodon lophanthoides var. geradianus. The structure of the new compound 1 was established using spectroscopic methods including extensive 1D and 2D NMR analysis. ...

journal_title：Natural product research

authors： Liu YH,Huang SX,Zhao QS,Ding JK,Goh NK,Sun HD,Chia TF,Tan SN,Chia LS

更新日期：2008-01-01 00:00:00

abstract：:The antitumour activity of the hydroalcoholic extract of the leaf (PCL) and stem bark (PCB) of Prosopis cineraria (L.) in Swiss albino mice was evaluated against an Ehrlich ascites carcinoma (EAC) tumour model. The activity was assessed using survival time, peritoneal cells, haematological studies, lipid peroxidation,...

journal_title：Natural product research

authors： Robertson S,Narayanan N,Raj Kapoor B

更新日期：2011-04-01 00:00:00

abstract：:Bothrops jararacussu venom's (Bj2015) batch was biomonitored quarterly for one year to assess phospholipase A2 (PLA2) activity, immunogenicity, neurotoxicity, and myotoxicity. In silico models were applied to evaluate losses using decay model and recoveries by predictive trend analysis. Mice were immunized with Bj2015...

journal_title：Natural product research

authors： Oliveira ICF,Mora AD,Neto JB,de Oliveira ÁL,Harder C,Hanai-Yoshida VM,Cogo JC,Floriano RS,Bonventi Junior W,Oliveira SJ,Oshima-Franco Y

更新日期：2019-08-01 00:00:00

abstract：:The serotonin (5-hydroxytryptamine) type 3 receptor is an important target in the control of digestive dysfunction such as anorexia and bulimia, and 5-HT3 receptor antagonists are effective against eating disorder and the early-phase chemotherapy and radiotherapy evoked vomiting. Our previous research of Valeriana jat...

journal_title：Natural product research

authors： Wang LX,Chen HL,Yan HL,Tang F,Zhang H,Li HX,Ye Q,Peng C,Tan YZ

更新日期：2019-09-10 00:00:00

abstract：:A novel isoindole alkaloid named oleraisoindole (1), together with six known compounds, 7'-ethoxy-trans-feruloyltyramine (2), N-trans-feruloyltyramine (3), N-trans-feruloyl-3-methoxytyramine (4), N-trans-p-coumaroyltyramine (5) aurantiamide (6) and ferulic acid methyl ester (7) were isolated from Portulaca oleracea L....

journal_title：Natural product research

authors： Jiang M,Zhang W,Yang X,Xiu F,Xu H,Ying X,Stien D

更新日期：2018-10-01 00:00:00

abstract：:Michael reaction acceptors (MRAs) are a class of active compounds. There is a great prospect to screen STAT3 inhibitors from Eupatorium lindleyanum, furthermore, to discover lead compounds for anti-triple-negative breast cancer (TNBC). In this study, glutathione (GSH) was employed, and a UPLC-MS screening method was d...

journal_title：Natural product research

authors： Yang B,Shen JW,Zhou DH,Zhao YP,Wang WQ,Zhu Y,Zhao HJ

更新日期：2019-02-01 00:00:00

abstract：:A new triterpene, javablumine A (1) along with six known ones were isolated from the aerial parts of Sambucus javanica Blume. They were identified as 3β,23-dihydroxy-11α,12α-epoxy-urs-20(30)-en-28,13β-olide (1), ursolic acid (2), pomolic acid (3), oleanic acid (4), 2α-hydroxy-oleanolic acid (5), α-amyrin (6), and lupe...

journal_title：Natural product research

authors： Chen F,Liu DL,Wang W,Lv XM,Li W,Shao LD,Wang WJ

更新日期：2020-10-01 00:00:00

abstract：:A new pentacyclic triterpenoid fatty acid ester, lupan-20-ol-3(β)-yl hexadecanoate (1), together with lupan-20-ol-3(β)-yl acetate (2), olean-18-en-3(β)-yl hexadecanoate (3), dotriacontanoic acid (4), stigmasterol (5), rubiadin (6), nonadecanoic acid (7), palmitic acid (8) and camptothecin (9) were isolated from the he...

journal_title：Natural product research

authors： Rajan R,Venkataraman R,Baby S

更新日期：2016-10-01 00:00:00

abstract：:From the leaves of Mallotus apelta two new benzopyran compounds (1,2) were obtained and their structures were determined using spectroscopic methods. ...

journal_title：Natural product research

authors： An TY,Hu LH,Cheng XF,Chen ZL

更新日期：2003-10-01 00:00:00

abstract：:The leaves of Alchornea floribunda and Alchornea cordifolia are used traditionally as topical anti-inflammatory agents. In this study, two highly lipophilic fractions AFLF and ACLF isolated from A. floribunda and A. cordifolia leaves respectively were investigated for topical anti-inflammatory effects using xylene-ind...

journal_title：Natural product research

authors： Okoye FB,Osadebe PO,Nworu CS,Okoye NN,Omeje EO,Esimone CO

更新日期：2011-12-01 00:00:00

abstract：:Fructose feeding induces a rise in blood pressure in normal rats that is associated with insulin resistance, hyperinsulinemia, hyperglycaemia, hypercholesterolaemia and hypertriglyceridaemia. We have examined the effect of chronic administration of A-HRS (100 and 300 mg kg⁻¹; p.o.) isolated from Hibiscus rosa sinensis...

journal_title：Natural product research

authors： Mohan M,Khade B,Shinde A

更新日期：2012-01-01 00:00:00

abstract：:A new malyngamide (1) was isolated along with seven known compounds (2-8) from the marine cyanobacterium Moorea producens collected in Hawaii. Compound 1 represented the first reported malyngamide with a hydroxy moiety at C-7 of the characteristic fatty acid portion of the compound. Compound 1 showed cytotoxicity agai...

journal_title：Natural product research

authors： Jiang W,Zhou W,Othman R,Uchida H,Watanabe R,Suzuki T,Sakamoto B,Nagai H

更新日期：2018-01-01 00:00:00

abstract：:Two new flavanone glycosides have been isolated from the water soluble part of Veratrum nigrum L., belonging to the family Lilica. The structures of 3',4'-dimethoxyl-quercitrin and 4'-methoxyl-glucotricin have been established with the aid of extensive NMR spectroscopic studies. ...

journal_title：Natural product research

authors： Li HL,Tang J,Liu RH,Zhang C,Zhang WD

更新日期：2009-01-01 00:00:00

abstract：:A new oleanane triterpenoid (2) was isolated from the roots of Rubia philippinensis. The structure of 2 was determined by analysis of HRMS and NMR data and identified as a rubiprasin analogue, 16β-hydroxyrubiprasin B. Four related known compounds were also encountered which include rubiprasin B (1), maslinic acid (3),...

journal_title：Natural product research

authors： Quan KT,Min BG,Hwang IH,Choi YJ,Kim SK,Na M

更新日期：2019-07-25 00:00:00

abstract：:The extent of the microbial contamination of the seventeenth-century wall paintings in the nave of the old Church of the Holy Ascension (Veliki Krčimir, Serbia) was evaluated via newly implemented ATP bioluminescence method, and traditional cultivation-based method, utilising commercially available dip slides. To asse...

journal_title：Natural product research

authors： Unković N,Ljaljević Grbić M,Stupar M,Vukojević J,Subakov-Simić G,Jelikić A,Stanojević D

更新日期：2019-04-01 00:00:00

abstract：:Two new benzoic acid derivatives, named methyl(S)-3-hydroxy-4-(2- hydroxy -6-methylheptan-2-yl)benzoate (1) and 2-hydroxy-3-(6- hydroxy-6-methylhept-1-en-2-yl)benzoic acid (2), were isolated from the ethanol extract of an endophytic fungus Aspergillus versicolor derived from the medicinal plant Euphorbia royleana. The...

journal_title：Natural product research

authors： Ye Y,Chen Y,Hou Y,Yu H,Zhu L,Sun Y,Zhou M,Chen Y,Dong M

更新日期：2020-06-11 00:00:00

abstract：:This study aimed at evaluating the impact of environmental factors on the accumulation of various components in Hedera helix L. folium collected from different European countries. The obtained results of studied samples showed that the antioxidant capacities were in the range of 0.027 to 0.688 mg/g. Contents of active...

journal_title：Natural product research

authors： Bezruk I,Materiienko A,Gubar S,Proskurina K,Budanova L,Ivanauskas L,Georgiyants V

更新日期：2020-11-04 00:00:00

abstract：:A new phenolic glycoside, 6-O-(4'-hydroxy-3',5'-dimethoxybenzoyl)-d-glucopyranose (4), and nine known compounds (1-3 and 5-10) were isolated from Juglans mandshurica Maxim. Compound structures were elucidated by NMR, HR-ESI-MS and acid hydrolysis. Compounds 5 and 6 are reported from this genus for the first time. Amon...

journal_title：Natural product research

authors： Yao D,Jin M,Zhang C,Luo J,Li R,Zheng M,Cui J,Li G

更新日期：2014-01-01 00:00:00

abstract：:A total of nine oilseeds with more than 15 wt% oil have been investigated for evaluating them as feedstock for biodiesel industries. Fatty acid profiles of all the nine oil samples have been determined by GC-MS analysis. The saponification numbers, gross heats of combustion of the oils and those of corresponding fatty...

journal_title：Natural product research

authors： Barua P,Dutta K,Basumatary S,Deka DC,Deka DC

更新日期：2014-01-01 00:00:00

abstract：:Cynanchum acutum L. subsp. sibiricum (Willd.) Rech. f. was extracted with hexane, acetone, methanol and water individually. A sample was heated in water then extracted with ethyl acetate. Among the extracts, the ethyl acetate extract exhibited the most antiproliferative activity, so isolation of bioactive compounds wa...

journal_title：Natural product research

authors： Yildiz I,Sen O,Erenler R,Demirtas I,Behcet L

更新日期：2017-11-01 00:00:00

abstract：:The world's rainforests hold untold potential for drug discovery. Rainforest plants are thought to contain evolved defensive active metabolites of greater diversity compared to plants from temperate regions. In recent years, the interest and overall output from pharmaceutical companies on novel antibacterial agents ha...

journal_title：Natural product research

authors： Othman M,Genapathy S,Liew PS,Ch'ng QT,Loh HS,Khoo TJ,Wiart C,Ting KN

更新日期：2011-11-01 00:00:00

abstract：:This study discusses the similarities and differences between the antioxidant activities of some essential oils: thyme (Thymus vulgaris), basil (Ocimum basilicum), peppermint (Mentha piperita), clove (Caryophyllus aromaticus), summer savory (Satureja hortensis), sage (Salvia hispanica) and lemon (Citrus limon (L.) Bur...

journal_title：Natural product research

authors： Dawidowicz AL,Olszowy M

更新日期：2014-01-01 00:00:00

abstract：:The chemical analyses of ethyl acetate-methanol (EtOAc-MeOH) extract of muricid gastropod mollusk, Chicoreus ramosus from the southeastern coast of Indian peninsular led to the identification of unprecedented cembrane-type diterpenoid, which was characterized as (3E, 6E, 10E)-8a-butoxy-17(15→14), 20(12→11)-bis-abeo-ce...

journal_title：Natural product research

authors： Chakraborty K,Salas S,Joy M

更新日期：2020-06-01 00:00:00

abstract：:Phytochemical investigation of methanolic extract of Adenium obesum led to the isolation of 42 (1-42) compounds belongs to cardiac glycosides, triterpenoids and steroids. The chemical structures of isolated compounds were elucidated by spectral techniques UV, IR, NMR and FAB MS. The cardiac glycosides were tested agai...

journal_title：Natural product research

authors： Ahmed SK,Versiani MA,Ikram A,Sattar SA,Faizi S

更新日期：2017-05-01 00:00:00

abstract：:In this study, Moringa oleifera flower extract and a trypsin inhibitor (MoFTI) isolated from it were evaluated for anti-protozoal activity against Trypanosoma cruzi and cytotoxicity to mammalian cells. The presence of flavonoids was remarkable in the HPLC fingerprints of the extract at 254 and 360 nm. Amino acid seque...

journal_title：Natural product research

authors： Pontual EV,Pires-Neto DF,Fraige K,Higino TMM,Carvalho BEA,Alves NMP,Lima TA,Zingali RB,Coelho LCBB,Bolzani VS,Figueiredo RCBQ,Napoleão TH,Paiva PMG

更新日期：2018-12-01 00:00:00

abstract：:One new sesqui-neolignan compound, namely, sesqui-illisimonan A (1), one new neolignan, illisimonan A (2), and one new phenylpropanoid compound, illisimoid A (3) were isolated from the fruits of Illicium simonsii Maxim. The structures and absolute configurations of these compounds were determined by extensive spectros...

journal_title：Natural product research

authors： Zhuang PY,Chen MH,Wang YN,Wang XX,Feng YJ,Zhang DY

更新日期：2018-10-01 00:00:00

abstract：:Lappaconitine is an important alkaloid of the aconite family and its biological activity is closely related to its structure. Through an X-ray structure analysis of hydrated lappaconitine hydrobromide, which was synthesised by us through a new method, the absolute configuration of lappaconitine was determined: monocli...

journal_title：Natural product research

authors： Sun W,Wang Y,Zhang J,Yu K

更新日期：2009-01-01 00:00:00

abstract：:A new chalcone named as balanochalcone (1) together with eight known compounds, methyl caffeate (2), β-hydroxydihydrochalcone (3), methyl gallate (4), dimethyl-6,9,10-trihydroxybenzo[kl]xanthene-1,2-dicarboxylate (5), p-coumaric acid (6), quercetin (7), scopoletin (8) and pinoresinol (9) have been isolated from the et...

journal_title：Natural product research

authors： Quang DN,So TC,Thanh NTP,Hoa LTP,Dien PH,Luong TM,Tung NQ,Long LD,Dai TD,Tien NQ

更新日期：2018-04-01 00:00:00