A new lupane-type triterpenoid fatty acid ester and other isolates from Ophiorrhiza shendurunii.

Abstract:

:A new pentacyclic triterpenoid fatty acid ester, lupan-20-ol-3(β)-yl hexadecanoate (1), together with lupan-20-ol-3(β)-yl acetate (2), olean-18-en-3(β)-yl hexadecanoate (3), dotriacontanoic acid (4), stigmasterol (5), rubiadin (6), nonadecanoic acid (7), palmitic acid (8) and camptothecin (9) were isolated from the hexane and chloroform extracts of Ophiorrhiza shendurunii from South India. Structures of the isolates were determined by (1)H, (13)C, (13)C DEPT, (1)H-(1)H COSY, HMBC, HSQC, NOESY NMR, FT-IR, DART-MS, ESI-MS, alkaline hydrolysis, derivatisation, GC-MS and HPTLC analyses. O. shendurunii hexane and chloroform extracts showed significant activities against Candida albicans and Fusarium oxysporum. Compounds 1 to 3 showed only moderate antiyeast/antifungal activities.

journal_name

Nat Prod Res

journal_title

Natural product research

authors

Rajan R,Venkataraman R,Baby S

doi

10.1080/14786419.2016.1160232

subject

Has Abstract

pub_date

2016-10-01 00:00:00

pages

2197-203

issue

19

eissn

1478-6419

issn

1478-6427

journal_volume

30

pub_type

杂志文章
  • Bioactive triterpenoids from the leaves of Eriobotrya japonica as the natural PDE4 inhibitors.

    abstract::The ethanolic extract of the leaves of Eriobotrya japonica exhibited inhibitory activity against phosphodiesterase-4D (PDE4D), which is a therapeutic target of inflammatory disease. Subsequent bioassay-guided fractionation led to the isolation of a new triterpene (1), together with seven known triterpenoids, methyl co...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2017.1300796

    authors: Tan BX,Yang L,Huang YY,Chen YY,Peng GT,Yu S,Wu YN,Luo HB,He XX

    更新日期:2017-12-01 00:00:00

  • Evaluation of chemical profile and antioxidant activity of Tripleurospermum insularum, a new species from Turkey.

    abstract::This article presents the very first phytochemical investigation on new species Tripleurospermum insularum Inceer & Hayırlıoglu-Ayaz. The volatile profile of odorous parts of the plant was analysed by GC/MS, and compounds were identified in headspace and essential oil obtained from aerial parts, representing 70.81% an...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2014.968156

    authors: Ćavar Zeljković S,Ayaz FA,Inceer H,Hayirlioglu-Ayaz S,Colak N

    更新日期:2015-02-01 00:00:00

  • A new compound, jolynamine, from marine brown alga Jolyna laminarioides.

    abstract::A new compound, jolynamine (1), was isolated from the marine brown alga Jolyna laminarioides collected from the coast of Karachi, Pakistan. In addition, four known compounds, namely saringosterol (2), loliolide (3), methyl-4-hydroxybenzoate (4) and propyl-4-hydroxybenzoate (5), were isolated for the first time from th...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2010.509722

    authors: Khan AM,Noreen S,Imran ZP,Choudhary MI

    更新日期:2011-05-01 00:00:00

  • Herbicidal effects of extracts and residue incorporation of Datura metel against parthenium weed.

    abstract::The present study was designed to evaluate the herbicidal activity of Datura metel against the noxious weed parthenium (Parthenium hysterophorus L.). In a laboratory bioassay, the effect of aqueous, methanol and n-hexane shoot and root extracts of 5, 10, 15 and 20% w/v (on a fresh weight basis) concentration of D. met...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786410903075440

    authors: Javaid A,Shafique S,Shafique S

    更新日期:2010-09-01 00:00:00

  • Polyol monoterpenes isolated from Chenopodium ambrosioides.

    abstract::Phytochemical study on the 95% ethyl alcohol extract of stems of Chenopodium ambrosioides resulted in the isolation of two new polyol monoterpenes, 4-hydroxy-4(α or β)-isopropyl-2-methyl-2-cyclohexen-1-one (1) and 1-methyl-4β- isopropyl-1-cyclohexene-4α,5α,6α-triol (2), together with five known compounds, (1S,2S,3R,4S...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2017.1314278

    authors: Hou SQ,Li YH,Huang XZ,Li R,Lu H,Tian K,Ruan RS,Li YK

    更新日期:2017-11-01 00:00:00

  • In vitro and in vivo studies of Cucurbita pepo L. flowers: chemical profile and bioactivity.

    abstract::Edible flowers consumption has increased in recent years due to their rich content of healthy phytochemicals. The aim of this study was to analyse the chemical profile of Cucurbita pepo L. flowers, and to explore their antioxidant and hypoglycaemic properties. Moreover, in order to assess in vivo effects, biochemical ...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2019.1672067

    authors: Morittu VM,Musco N,Mastellone V,Bonesi M,Britti D,Infascelli F,Loizzo MR,Tundis R,Sicari V,Tudisco R,Lombardi P

    更新日期:2019-09-30 00:00:00

  • Chemical composition and antimicrobial activity of the essential oils of some species of Anthemis sect. Anthemis (Asteraceae) from Sicily.

    abstract::The chemical composition of the essential oils isolated from the aerial parts of Anthemis arvensis L. subsp. arvensis, Anthemis cretica subsp. messanensis (Brullo) Giardina & Raimondo and from flowers and leaves of Anthemis cretica subsp. columnae (Ten.) Frezén were determinated by GC-FID and GC-MS analyses. Torreyol ...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2017.1297444

    authors: Riccobono L,Maggio A,Bruno M,Spadaro V,Raimondo FM

    更新日期:2017-12-01 00:00:00

  • Iridoids and phenylethanoid glycosides from the aerial parts of Ajuga tenorei, an endemic Italian species.

    abstract::We report the first analysis in absolute, and in particular, concerning the phytochemical pattern, about an endemic Italian species, Ajuga tenorei C. Presl. The analysis, performed by means of techniques such as Column Chromatography and NMR spectroscopy and Mass spectrometry, led to the isolation and the identificati...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2016.1218490

    authors: Frezza C,Venditti A,Di Cecco M,Ciaschetti G,Serafini M,Bianco A

    更新日期:2017-01-01 00:00:00

  • A new natural nucleotide and other antibacterial metabolites from an endophytic Nocardia sp.

    abstract::Nine compounds were isolated from Nocardia sp. YIM 64630, and their structures were elucidated as 5'-O-acetyl-2'-deoxyuridine (1), 22E,24R-5α,6α-epoxyergosta-8(14),22-diene-3β,7α-diol (2), 22E,24R-5α,6α-epoxyergosta-8,22-diene-3β,7α-diol (3), 22E,24R-ergosta-7,22-diene-3β,5α,6β-triol (4), 5α,8α-epidioxyergosta-6,22-di...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2014.964713

    authors: Li W,Yang X,Yang Y,Qin S,Li Q,Zhao L,Ding Z

    更新日期:2015-01-01 00:00:00

  • Rapid characterisation of flavonoids from Sophora alopecuroides L. by HPLC/DAD/ESI-MSn.

    abstract::An HPLC/DAD/ESI-MSn method was established to characterise flavonoids in the seeds of Sophora alopecuroides L. All the flavonoids exhibited abundant [M-H]- ions, which triggered data-dependent multistage mass spectrometry fragmentations. Characteristic UV spectra were used to confirm flavonoid subtypes. In total, 22 f...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2012.688052

    authors: Yang WZ,Ye G,Meng AH,Sabir G,Qiao X,Guo DA,Ye M

    更新日期:2013-03-01 00:00:00

  • Antitubercular and cytotoxic polyoxygenated cyclohexane derivatives from Uvaria grandiflora.

    abstract::Chromatographic purification of the DCM sub-extract of Uvaria grandiflora led to the isolation and characterization of a new polyoxygenated cyclohexane derivative, grandifloranol (1), together with five known compounds. Among the compounds isolated, zeylenone (3) showed moderate antitubercular activity against Mycobac...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2020.1741579

    authors: Macabeo APG,Flores AIG,Fernandez RAT,Budde S,Faderl C,Dahse HM,Franzblau SG

    更新日期:2020-03-23 00:00:00

  • Agronomic, metabolomic and lipidomic characterisation of Sicilian Origanum vulgare (L.) ecotypes.

    abstract::Although Origanum vulgare (L.) has been deeply analysed at phytochemical level, poor knowledge is available regarding non-volatile compounds such as lipids. The aim of this work was to characterise five wild Sicilian Origanum ecotypes from an agronomic, metabolomic and lipidomic perspective. Serradifalco presented hig...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2015.1104672

    authors: Tuttolomondo T,Martinelli F,Mariotti L,Leto C,Maggio A,La Bella S

    更新日期:2016-01-01 00:00:00

  • Two new diprenylated flavanones from Derris laxiflora Benth.

    abstract::Phytochemical reinvestigation on the whole plants of Derris laxiflora Benth. afforded two new diprenylated flavanones, derriflavanones B and C (1-2), together with thirty-two known compounds, including sixteen flavonoids (3-18), eleven aromatic compounds (19-29), and five chlorophylls (30-34). All known compounds were...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2019.1576039

    authors: Huang HC,Chien SC,Kuo CC,Wu MD,Cheng MJ,Chen JJ,Chiu HL,Kuo YH

    更新日期:2020-08-01 00:00:00

  • Microbial transformation of the anti-diabetic agent corosolic acid.

    abstract::Biotransformation of corosolic acid (1) by Cochliobolus lunatus and Streptomyces asparaginoviolaceus afforded four metabolites, which were identified by using (1)H NMR, (13)C NMR, DEPT, HSQC, HMBC and NOESY spectral data. Biotransformation of corosolic acid by C. lunatus R.R. Nelson & Haasis CGMCC 3.4381 produced thre...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2014.955485

    authors: Feng X,Li DP,Zhang ZS,Chu ZY,Luan J

    更新日期:2014-01-01 00:00:00

  • Screening of ecotoxicological, qualitative and reproductive variables in male European sea bass Dicentrarchus labrax (L.) reared in three different fish farms: Facility location and typology.

    abstract::The aim of this study was to investigate the influence of both facility location and typology of fish farm on some ecotoxicological, qualitative and reproductive variables in European sea bass Dicentrarchus labrax L. Several variables were investigated: gonado-somatic index (GSI), liver-somatic index (LSI); 7-ethoxyre...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2012.678353

    authors: Cangialosi MV,Corsi I,Bonacci S,Sensini C,Cicero N,Focardi S,Mazzola A

    更新日期:2013-04-01 00:00:00

  • New polysulphanes from aerial parts of Ferula behboudiana Rech. f. & Esfand.

    abstract::The chloroformic extract of the aerial parts of Ferula behboudiana (Umbelliferae) afforded four new polysulphane derivatives: 1-sec-butyl-2-[(E)-3-(methylthio)prop-1-enyl]disulphane (1), 1-sec-butyl-2-[(Z)-3-(methylthio)prop-1-enyl]disulphane (2), 1-[(E)-3-(methylthio)prop-1-enyl)-2-(1-(methylthio)propyl]disulphane (3...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786410903458273

    authors: Yousefi M,Mohammadi M,Habibi Z,Shafiee A

    更新日期:2010-09-01 00:00:00

  • Lycopus europaeus: phenolic fingerprint, antioxidant activity and antimicrobial effect on clinical Staphylococcus aureus strains.

    abstract::Lycopus europaeus L. leaves water extract (LEL) was subjected to phytochemical analysis, and evaluated for its antibacterial and antioxidant effects. Antibacterial activity testing was performed on Staphylococcus aureus clinical strains from catheter-related and skin infections by broth microdilution test. LEL showed ...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2015.1010086

    authors: Fialová S,Slobodníková L,Veizerová L,Grančai D

    更新日期:2015-01-01 00:00:00

  • Isolation of amylase regulators from the leaves of Ixeridium dentatum.

    abstract::Two new compounds, one sesquiterpene lactone (1) and one phenylethanoid tautomer (2), together with eleven known compounds (3-13) were isolated from the leaves of Ixeridium dentatum. Their structures were determined by extensive spectroscopic methods, including 1D-, 2D-NMR, and mass spectrometry. All compounds were ev...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2019.1599885

    authors: Park S,Nhiem NX,Park JH,Bhattarai KR,Chae HJ,Kim HR,Kim SH

    更新日期:2019-04-10 00:00:00

  • Kitamycin C, a new antimycin-type antibiotic from Streptomyces antibioticus strain 200-09.

    abstract::An actinomycete strain 200-09, isolated from a soil sample collected from the coast of Hawaii, USA, was identified as Streptomyces antibioticus on the basis of its morphological, physiological and biochemical characteristics as well as 16S rDNA analysis. A new antimycin-type antibiotic, kitamycin C (1), together with ...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2017.1295240

    authors: Wang F,Fu SN,Bao YX,Yang Y,Shen HF,Lin BR,Zhou GX

    更新日期:2017-08-01 00:00:00

  • Three new phenanthrenes, a new stilbenoid isolated from the roots of Stemona tuberosa Lour. and their cytotoxicity.

    abstract::Three new phenanthrenes, stemophenanthrenes A-C (1-3), along with one new stilbenoid, isopinosylvin A (4) and a known compound methyl ferulate (5), were isolated and identified from the roots of Stemona tuberosa Lour. plants, collected in Attapu province (Laos). Their structures were elucidated by spectroscopic analys...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2013.832677

    authors: Khamko VA,Quang DN,Dien PH

    更新日期:2013-01-01 00:00:00

  • Studies on the chemical constituents of Phyllanthus emblica.

    abstract::Phytochemical investigations on Phyllanthus emblica have resulted in the isolation of the two new flavonoids, kaempferol-3-O-alpha-L-(6''-methyl)-rhamnopyranoside (1) and kaempferol-3-O-alpha-L-(6''-ethyl)-rhamnopyranoside (2). Their structures were determined on the basis of extensive spectroscopic studies including ...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786410601124664

    authors: Habib-ur-Rehman,Yasin KA,Choudhary MA,Khaliq N,Atta-ur-Rahman,Choudhary MI,Malik S

    更新日期:2007-07-20 00:00:00

  • A new megastigmane sulphoglycoside and polyphenolic constituents from pericarps of Garcinia mangostana.

    abstract::A megastigmane sulphoglycoside together with three phenolic compounds were isolated from the water-soluble fraction of the pericarps of Garcinia mangostana. The structure of the new compound was determined as 4-O-sulpho-β-d-glucopyranosyl abscisate (1) by spectroscopic data. Proanthocyanidin A2 (2) showed potent α-glu...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2015.1126261

    authors: Tran TH,Le Huyen T,Tran TM,Nguyen TA,Pham TB,Nguyen Tien D

    更新日期:2016-07-01 00:00:00

  • Ent-trachylobane-3β-hydroperoxide, a new diterpene from the root bark of Chrozophora oblongifolia (Fam.; Euphorbiaceae).

    abstract::New ent-trachylobane-3β-hydroperoxide (5) together with four known compounds, ricinine (1), trimethoxy ellagic acid (2), dimethoxy ellagic acid (3) and aleurotolic acid (4) were isolated from the methylene chloride fraction of the root bark of Chrozophora oblongifolia. The structures of these secondary metabolites wer...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2019.1687477

    authors: Kamel MR,Nafady AM,Hassanein AMM,Hassan AR,Shimizu K,Ibrahim RR,Haggag EG

    更新日期:2019-11-06 00:00:00

  • Solid-phase microextraction of volatile organic compounds released from leaves and flowers of Artemisia fragrans, followed by GC and GC/MS analysis.

    abstract::The chemical composition of the volatile organic compounds (VOCs) released from the leaves and flowers of Artemisia fragrans Willd. (Asteraceae) was investigated using headspace solid-phase microextraction (HS-SPME) coupled to gas chromatography (GC) and/or GS/mass spectrometry (GC/MS). The efficiency and reliability ...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786410903108951

    authors: Movafeghi A,Djozan Dj,Torbati S

    更新日期:2010-08-01 00:00:00

  • Chemical composition and antimicrobial activities of Perovskia artemisioides Boiss. essential oil.

    abstract::The Perovskia artemisioides Boiss. essential oil obtained by hydrodistillation method of flowers growing wild in the north of Iran. The study led to the identification of 29 compositions by a combination of HP-5 GC-FID and GC-MS analytical techniques. The constituents were identified in P. artemisioides essential oil ...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2015.1101694

    authors: Hafez Ghoran S,Azadi B,Hussain H

    更新日期:2016-09-01 00:00:00

  • A novel and efficient synthesis of 3,4-dihydroxyphenylacetic ester and amide derivatives/conjugates and assessment of their antioxidant activity.

    abstract::Phenolic acids, a sub-class of polyphenols, are widely studied. By contrary, 3,4-dihydroxyphenylacetic acid is scarcely studied. For this purpose, a series of 3,4-dihydroxyphenylacetic acid ester and amide derivatives/conjugates were synthesised for the first time. A systematic study has been performed to quantitative...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2017.1342090

    authors: Pagoni A,Vassiliou S

    更新日期:2018-06-01 00:00:00

  • A bioanalytical approach of chemical composition, bioactivity and cytotoxicity of Berteroa incana L. herb.

    abstract::Berteroa incana is a wild herb widespread in temperate zones which was practically not studied for its biological effects. Methanolic and aqueous extracts of B. incana were assessed for the content in polyphenols and the related antioxidant and antimicrobial activities and the polysaccharide extract for the content in...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2017.1380014

    authors: Ungureanu O,Gatea F,Seciu AM,Teodor ED,Nicorescu IM,Radu GL

    更新日期:2018-12-01 00:00:00

  • Hypepontine, a new quaternary alkaloid with antimicrobial properties.

    abstract::New isoquinoline alkaloid hypepontine (1) together with a five known compounds, were identified in Hypecoum ponticum Velen, the partial synonym of Hypecoum procumbens L. The structure of the new substance was elucidated based on spectroscopic evidence. The tertiary and quaternary alkaloid mixtures as well as the isola...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2018.1495640

    authors: Doncheva T,Kostova N,Valcheva V,Toshkovska R,Vutov V,Philipov S

    更新日期:2020-03-01 00:00:00

  • Myrcia hatschbachii: antifungal activity and structural elucidation of ellagic and 3-O-methyl ellagic acids.

    abstract::Natural products, especially plants, have been investigated as sources of new substances with antimicrobial properties. In this context, the Myrcia genus is extensively researched for presenting such activities. This work aims to evaluate the antifungal, antibacterial, and antioxidant properties of extracts and fracti...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2020.1793149

    authors: Gatto LJ,Veiga A,Gribner C,Moura PF,Rech KS,Murakami FS,Dias JFG,Miguel OG,Miguel MD

    更新日期:2020-07-13 00:00:00

  • Chemical constituents of Geum urbanum L. roots.

    abstract::A new dehydrodigallic acid derivative (1), along with 19 known compounds, including 6 phenolic derivatives, 2 steroids and 11 triterpenoids were isolated from the ethanol extract of the root of Geum urbanum. Herein, there is the first report of steroid and triterpene in Geum urbanum. The purified metabolites were char...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2018.1425844

    authors: Ton That Q,Nguyen Thien TV,Dang HP,Le Hoan N,Vo LKT,Nguyen MHD,Ngu NT,Nguyen TS,Hansen PE

    更新日期:2018-11-01 00:00:00