A novel and efficient synthesis of 3,4-dihydroxyphenylacetic ester and amide derivatives/conjugates and assessment of their antioxidant activity.

abstract：:Four xanthones were isolated from Gentianopsis paludosa Ma and were identified by modern spectroscopic methods. Cytotoxicity of the four xanthones was tested on HepG2 cells and HL-60 cells by sulphorhodamine B (SRB) assay. Clonogenic survival assay, trypan blue exclusion method, AO/EB staining and DNA fragmentation as...

journal_title：Natural product research

authors： Ding L,Liu B,Zhang SD,Hou Q,Qi LL,Zhou QY

更新日期：2011-04-01 00:00:00

abstract：:A new denudatine-type C20-diterpenoid alkaloid, pubesine (1), along with seven known diterpenoid alkaloids, altaconitine (2), 14-benzoylaconine (3), spicatine A (4), 14-benzoylaconine-8-palmitate (5), 14-O-acetylsenbusine A (6), senbusine A (7) and 14-acetylneoline (8) were isolated from the whole plant of Aconitum so...

journal_title：Natural product research

authors： Chen L,Shan L,Xu W,Zhang J,Huang S,Zhou X

更新日期：2017-03-01 00:00:00

abstract：:The purpose of this study is the determination of chemical composition and antioxidant activity of essential oils (EOs) from Saussurea costus (Falc.) Lipsch. Roots have been collected on December of the first plant year (IY) and in April, August and December of the third plant year (I, 6B, D7). A GC analysis was carri...

journal_title：Natural product research

authors： Benedetto C,D'Auria M,Mecca M,Prasad P,Singh P,Singh S,Sinisgalli C,Milella L

更新日期：2019-08-01 00:00:00

abstract：:In this study, phenolic compounds of hazelnut leaves of 10 different cultivars with the same cultural, geographical, geological and climatic conditions were analyzed by HPLC/DAD and HPLC/DAD/MS/MS - ESI. Eight phenolic compounds (3-caffeoylquinic acid, 5-caffeoylquinic acid, caffeoyltartaric acid, p-coumaroyltartaric ...

journal_title：Natural product research

authors： Amaral JS,Ferreres F,Andrade PB,Valentão P,Pinheiro C,Santos A,Seabra R

更新日期：2005-02-01 00:00:00

abstract：:Essential oils from aerial parts of Senecio nutans, Senecio viridis, Tagetes terniflora and Aloysia gratissima were analysed by GC-MS and their antifungal activities were assayed on toxigenic Fusarium and Aspergillus species. Sabinene (27.6 ± 0.1%), α-phellandrene (15.7 ± 0.3%), o-cymene (9.6 ± 0.2%) and β-pinene (6.1...

journal_title：Natural product research

authors： Galvez CE,Jimenez CM,Gomez ALA,Lizarraga EF,Sampietro DA

更新日期：2020-05-01 00:00:00

abstract：:Nerium oleander (NO), a member of the Apocynaceae family, is an ornamental plant. In this study, we evaluated the antiviral activity of hot and cold extract of NO against six different viruses such as herpes simplex virus type 1 (HSV-1), polio virus type 1 (Sb-1), vesicular stomatitis virus (VSV), reovirus type-1 (Reo...

journal_title：Natural product research

authors： Sanna G,Madeddu S,Serra A,Collu D,Efferth T,Hakkim FL,Rashan L

更新日期：2019-03-25 00:00:00

abstract：:Two new, aramatosides A and B (1 and 2), together with seven known oleanane-type triterpene saponins (3-9) were isolated from the leaves of Aralia armata. Their structures were determined by combination of HR-ESI-MS, 1 D and 2 D NMR spectral data as well as comparison with the previous literature. Compounds 6-9 exhibi...

journal_title：Natural product research

authors： Yen PH,Chuong NTH,Lien GTK,Cuc NT,Nhiem NX,Thanh NTV,Tai BH,Seo Y,Namkung W,Park S,Kim SH,Minh CV,Kiem PV

更新日期：2020-05-22 00:00:00

abstract：:SPME analysis of Zingiber officinale Roscoe and Curcuma longa L. were performed by using a DVB/CARB/PDMS fiber. The SPME analysis of Zingiber officinale showed that the main components found were camphene (7.27%), geranial (8.37%), α-zingiberene (14.50%), α-farnesene (9.14%), β-bisabolene (6.52%), and β-sesquiphelland...

journal_title：Natural product research

authors： D'Auria M,Racioppi R

更新日期：2019-07-01 00:00:00

abstract：:One new triterpenoid olean-18-ene-1β, 2α, 3β-triol (1) along with four known compounds were isolated from the chloroform extract of the aerial part of Salvia atropatana Bunge. The known compounds were two flavonoids, 5-hydroxy-7,4'-dimethoxyflavone (2) and 5-hydroxy-6,7,4'-trimethoxyflavone (3), an abietane-type diter...

journal_title：Natural product research

authors： Habibi Z,Cheraghi Z,Ghasemi S,Yousefi M

更新日期：2012-01-01 00:00:00

abstract：:A new sesquiterpenoid, malayscaphiol (1), and three known compounds, lupeol (2), lupenone (3) and stigmasterol (4), were isolated from the methanolic extract of the stem bark of Scaphium macropodum. The structures of the isolated compounds were determined using several spectroscopic methods, including UV-vis, FT-IR, 1...

journal_title：Natural product research

authors： Al Muqarrabun LM,Ahmat N,Aris SR,Shamsulrijal N,Baharum SN,Ahmad R,Rosandy AR,Suratman MN,Takayama H

更新日期：2014-01-01 00:00:00

abstract：:Flavonoids have always attracted much attention due to their reversal activity on multidrug resistance (MDR). Eight flavonoids isolated from traditional Chinese medicine Sophora alopecuroides L. were applied to test their effect on MDR associated protein 1 (MRP1) through the established predicting assay. Three flavono...

journal_title：Natural product research

authors： Ni K,Yang L,Wan C,Xia Y,Kong L

更新日期：2014-01-01 00:00:00

abstract：:A novel macrolide with dioxa and double ring pentadecanone, named as phoxalone, isolated from the culture broth of a myxobacterium Sorangium cellulosum WXNXJ-C, was well investigated. The chemical structure of Phoxalone was elucidated by spectroscopic analysis including UV, IR, (1)H NMR, MALDI-TOF-MS, and LC/MS spectr...

journal_title：Natural product research

authors： Guo WJ,Tao WY,Bi F

更新日期：2007-12-01 00:00:00

abstract：:Bothrops jararacussu venom's (Bj2015) batch was biomonitored quarterly for one year to assess phospholipase A2 (PLA2) activity, immunogenicity, neurotoxicity, and myotoxicity. In silico models were applied to evaluate losses using decay model and recoveries by predictive trend analysis. Mice were immunized with Bj2015...

journal_title：Natural product research

authors： Oliveira ICF,Mora AD,Neto JB,de Oliveira ÁL,Harder C,Hanai-Yoshida VM,Cogo JC,Floriano RS,Bonventi Junior W,Oliveira SJ,Oshima-Franco Y

更新日期：2019-08-01 00:00:00

abstract：:Alphitobius diaperinus is an important pathogen with worldwide distribution that causes severe economic loss of efficiency in broilers. This study evaluates the potential of organic extracts of two strains entomopathogenic fungus Beauveria bassiana (CG71 and UNI40) as a biocontrol agent on A. diaperinus and promotes t...

journal_title：Natural product research

authors： Daniel JFS,Scalco AV,de Souza RM,Ocampos FMM,Barison A,Alves LFA,Neves PMOJ

更新日期：2019-10-01 00:00:00

abstract：:This study aimed at evaluating the impact of environmental factors on the accumulation of various components in Hedera helix L. folium collected from different European countries. The obtained results of studied samples showed that the antioxidant capacities were in the range of 0.027 to 0.688 mg/g. Contents of active...

journal_title：Natural product research

authors： Bezruk I,Materiienko A,Gubar S,Proskurina K,Budanova L,Ivanauskas L,Georgiyants V

更新日期：2020-11-04 00:00:00

abstract：:Colletia paradoxa (Spreng.) Esc. (Rhamnaceae, Colletieae) is a medicinal plant, threatened with extinction in Brazil, presenting great morphological variability. Our objective is to investigate the phytochemical components, antioxidant capacity and antimycobacterial activity of different morphotypes of C. paradoxa in ...

journal_title：Natural product research

authors： Bastos Záchia NR,Piana M,Dos Santos Siqueira F,da Silva Jesus R,Athayde ML,Essi L,de Campos MMA

更新日期：2019-04-16 00:00:00

abstract：:The ethanolic extract of the fruits of Momordica dioica was studied for its protective and curative effect against gentamicin-induced acute renal injury in albino rats of both sexes. Gentamicin intoxicated group showed significant increase in blood urea (69.48 +/- 4.34) and serum creatinine (3.017 +/- 0.208) from norm...

journal_title：Natural product research

authors： Jain A,Singhai AK

更新日期：2010-09-01 00:00:00

abstract：:A new furan derivative named 3-(5-oxo-2,5-dihydrofuran-3-yl) propanoic acid (1) was isolated for the first time. Its structure was elucidated by UV, IR, NMR, HR-ESI-MS and the single-crystal X-ray diffraction spectroscopic data. Meanwhile, the antifungal and antibacterial activities of compound 1 was tested, it exhibi...

journal_title：Natural product research

authors： Yang XF,Wang NN,Kang YF,Ma YM

更新日期：2019-10-01 00:00:00

abstract：:The composition and antibacterial activity of the essential oil of the aerial flowering parts of Nepeta hormozganica Jamzad have been studied. Analysis of the oil was conducted by GC-FID and GC-MS. Thirty-two components were characterized accounting for 99.4% of the total oil. Oxygenated monoterpenes (87.5%) were foun...

journal_title：Natural product research

authors： Sonboli A,Saadat MH,Arman M,Kanani MR

更新日期：2017-12-01 00:00:00

abstract：:New isoquinoline alkaloid hypepontine (1) together with a five known compounds, were identified in Hypecoum ponticum Velen, the partial synonym of Hypecoum procumbens L. The structure of the new substance was elucidated based on spectroscopic evidence. The tertiary and quaternary alkaloid mixtures as well as the isola...

journal_title：Natural product research

authors： Doncheva T,Kostova N,Valcheva V,Toshkovska R,Vutov V,Philipov S

更新日期：2020-03-01 00:00:00

abstract：:The aqueous methanolic extracts of Melastoma malabathricum L. exhibited antibacterial activity when assayed against seven microorganisms by the agar diffusion method. Solvent fractionation afforded active chloroform and ethyl acetate fractions from the leaves and the flowers, respectively. A phytochemical study result...

journal_title：Natural product research

authors： Wong KC,Hag Ali DM,Boey PL

更新日期：2012-01-01 00:00:00

abstract：:Two new compounds including a new 3-arylcoumarin liquiritcoumarin (1), and a new flavonoid glycoside crotoliquiritin (2), together with twelve known compounds (3-14) were isolated from the radix and rhizome of Glycyrrhiza uralensis. Their structures were elucidated on the basis of extensive spectroscopic data analyses...

journal_title：Natural product research

authors： Wang M,Yang W,Liu X,Liu Q,Zheng H,Wang X,Shen T,Wang S,Ren D

更新日期：2020-01-30 00:00:00

abstract：:In this work, we report a rapid and convenient HPLC-UV-DAD method for the isolation of δ-T3 on semi-preparative scale from two different vitamin E rich processed, commercially available products obtained from the fruits of Elaeis guineensis Jacq. (oil palm) and from the seeds of Bixa orellana L. (achiote tree). Chroma...

journal_title：Natural product research

authors： Beretta G,Gelmini F,Fontana F,Moretti RM,Montagnani Marelli M,Limonta P

更新日期：2018-05-01 00:00:00

abstract：:A screening of Chinese medicinal herbs and wild plants for agrochemicals was carried out; the essential oil of Glycosmis lucida leaves was found to possess significant repellent activity against Tribolium castaneum and Liposcelis bostrychophila. It was found that the main components included elixene (19.81%), spathule...

journal_title：Natural product research

authors： Guo SS,Zhang WJ,Yang K,Liang JY,You CX,Wang CF,Li YP,Geng ZF,Deng ZW,Du SS

更新日期：2017-05-01 00:00:00

abstract：:Nine resorcinol derivatives including two new ones, 5-[(8Z,11Z,14Z)-nonadeca-8,11,14-trienyl] resorcinol (1) and 5-[(8Z,11Z,14E)-heptadeca-8,11,14-trienyl] resorcinol (2), were isolated from the leaves of Syzygium samarangense. The new structures were elucidated by means of extensive spectroscopic techniques including...

journal_title：Natural product research

authors： Hu YK,Wang L,Wang JH,Li MJ,Li F,Yang J,Zhao Y

更新日期：2020-08-13 00:00:00

abstract：:Oleiferoside B is a triterpenoid monomer compound, mainly isolated from roots of Camellia oleifera Abel, the underlying mechanism of its antitumour is not clear. In the present study, oleiferoside B potently inhibited SMMC-7721 and MCF-7 cells proliferation and cause cells apoptosis. In addition, it activated an autop...

journal_title：Natural product research

authors： Feng S,Zha Z,Wang Z,Yang P,Wu J,Li X,Xu Q,Liu Y

更新日期：2020-03-18 00:00:00

abstract：:Ginsenoside Re (G-Re) is a major ingredient of the ginseng bud. A novel and rapid method to isolate and purify G-Re from ginseng buds was established. The procedure involves solvent extraction of ginseng bud powder, then pre-purification with an active carbon column and purification by preparative HPLC (prep-HPLC). Ac...

journal_title：Natural product research

authors： Kuang P,Wang G,Yuan Q,Liang H

更新日期：2012-01-01 00:00:00

abstract：:A new prenylated indole alkaloid, named paraherquamide J (1), together with four known compounds (2-5), were isolated from the mangrove rhizosphere soil-derived fungus Penicillium janthinellum HK1-6. The planar structure and relative configuration of 1 were determined by detailed analysis of the spectroscopic data esp...

journal_title：Natural product research

authors： Zheng YY,Shen NX,Liang ZY,Shen L,Chen M,Wang CY

更新日期：2020-02-01 00:00:00

abstract：:Edible flowers consumption has increased in recent years due to their rich content of healthy phytochemicals. The aim of this study was to analyse the chemical profile of Cucurbita pepo L. flowers, and to explore their antioxidant and hypoglycaemic properties. Moreover, in order to assess in vivo effects, biochemical ...

journal_title：Natural product research

authors： Morittu VM,Musco N,Mastellone V,Bonesi M,Britti D,Infascelli F,Loizzo MR,Tundis R,Sicari V,Tudisco R,Lombardi P

更新日期：2019-09-30 00:00:00

abstract：:Although Origanum vulgare (L.) has been deeply analysed at phytochemical level, poor knowledge is available regarding non-volatile compounds such as lipids. The aim of this work was to characterise five wild Sicilian Origanum ecotypes from an agronomic, metabolomic and lipidomic perspective. Serradifalco presented hig...

journal_title：Natural product research

authors： Tuttolomondo T,Martinelli F,Mariotti L,Leto C,Maggio A,La Bella S

更新日期：2016-01-01 00:00:00