Abstract:
:Two new compounds including a new 3-arylcoumarin liquiritcoumarin (1), and a new flavonoid glycoside crotoliquiritin (2), together with twelve known compounds (3-14) were isolated from the radix and rhizome of Glycyrrhiza uralensis. Their structures were elucidated on the basis of extensive spectroscopic data analyses. All of the compounds were evaluated for the cytotoxic activities. Only compound 5 showed moderate effects with IC50 of 11.46 μM for A549 cells and IC50 of 7.38 μM for NCI-H292 cells. Compounds 1 and 2 were demonstrated to be Nrf2 pathway activators by using a stable antioxidant response element (ARE)-dependent reporter gene assay together with immunoblot and immunofluorescence analysis.
journal_name
Nat Prod Resjournal_title
Natural product researchauthors
Wang M,Yang W,Liu X,Liu Q,Zheng H,Wang X,Shen T,Wang S,Ren Ddoi
10.1080/14786419.2020.1715398subject
Has Abstractpub_date
2020-01-30 00:00:00pages
1-8eissn
1478-6419issn
1478-6427pub_type
杂志文章abstract::Phytochemical investigation of Eucommia ulmoides Oliver staminate flowers provided twenty-seven compounds, including 11 triterpenes (1-11), 4 fatty acids (12-15), 1 coumarin (16), 1 chromone (17), 7 flavonoids (18-24) and 3 cyclopeptide alkaloids (25-27). Compounds 4-6, 8-9, 11-15, 17 and 25-27 were reported for the f...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2020.1858411
更新日期:2020-12-12 00:00:00
abstract::A new anthraquinone (4) and three known anthraquinones (1-3) were isolated from Galium verum L. Their structures were identified as 1,3-dihydroxy-2-methylanthraquinone (1), physcion (2), 2-hydroxy-1,3-dimethoxyanthraquinone (3), 2,5-dihydroxy-1,3-dimethoxyanthraquinone (4) by means of chemical and spectroscopic analys...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786410600921532
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abstract::The stem bark of Cussonia bancoensis is used traditionally for the treatment of different types of infection and pain. A bioassay guided fractionation of the methanol stem bark extract led to the isolation of five pentacyclic triterpenes and glycosides identified based on spectroscopic data as 23-hydroxyursolic acid (...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2018.1503262
更新日期:2020-03-01 00:00:00
abstract::Physalins are seco-steroids with a variety of pharmacological activities already described. In this study the pharmacological properties of a standardized concentrated ethanolic extract from Physalis angulata (CEEPA), rich in physalins B, D, F and G, were studied in models of pain and inflammation in mice. Inflammator...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2019.1705812
更新日期:2019-12-24 00:00:00
abstract::A new protostane-type triterpenoid bearing an oxetane ring in the side-chain, named alisol W (1), has been obtained from the dried rhizome of Alisma plantago-aquatica subsp. orientale. The structure and absolute configuration of compound 1 was determined from extensive spectroscopic analysis. In addition, the vasorela...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2018.1519710
更新日期:2019-11-01 00:00:00
abstract::This manuscript describes the antioxidant activity of essential oil of Cinnamon (Cinnamomum zeylanicum) bark extracted by supercritical fluid extraction (SCFE), hydro distillation and steam distillation. The cinnamon bark essential oil exhibited a wide range of total phenolic contents, total flavonoid contents, reduci...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2014.1002088
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abstract::Nerium oleander (NO), a member of the Apocynaceae family, is an ornamental plant. In this study, we evaluated the antiviral activity of hot and cold extract of NO against six different viruses such as herpes simplex virus type 1 (HSV-1), polio virus type 1 (Sb-1), vesicular stomatitis virus (VSV), reovirus type-1 (Reo...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2019.1582046
更新日期:2019-03-25 00:00:00
abstract::Essential oils from the leaves, twigs and barks of Bocageopsis pleiosperma Maas were obtained by using hydrodistillation and analysed by using gas chromatography coupled to mass spectrometry. Several compounds (51) were detected and identified, being β-bisabolene the main component in all aerial parts of the plant, wi...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2014.996148
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abstract::A study on essential oil fractions of the Western Balkan endemic Sideritis romana L. subsp. purpurea (Tal. ex Benth.) Heywood collected in Montenegro is reported. The 24-h systematic steam distillation extraction procedure was performed. The gas chromatographic/mass spectrometric (GC/MS) analysis of the fractions show...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2017.1378212
更新日期:2018-05-01 00:00:00
abstract::From a biologically active fraction of extract from the fungus Fomitopsis pinicola, a new lanostane triterpene was isolated, 3alpha-acetyloxylanosta-8,24-diene-21-ol (1), along with two known triterpenic acids, (2) and (3). The structures of the compounds were elucidated based on their spectral properties. [structure:...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786410500520251
更新日期:2007-05-01 00:00:00
abstract::Plants, in their life cycle, are usually exposed to various kinds of non-biological stresses including heavy metals. One of these heavy metals is nickel which affects many physiological processes of plants. Studies have shown that the changes in planting conditions can affect the qualitative and quantitative features ...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2014.913240
更新日期:2014-01-01 00:00:00
abstract::A new germacrenolide (1) and fourteen known terpenoids (2-15) were isolated from the barks of Magnolia maudiae (Dunn) Figlar (Magnoliaceae). The structure of (7αH,11βH)-2α,8α-dihydroxy-4α,5β-epoxy-germacr-1(10)-en-6α,12-olide (1) was elucidated by physical and spectroscopic data analysis, including 1D, 2D NMR and HR-E...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2017.1385012
更新日期:2018-07-01 00:00:00
abstract::Leaves of Kalanchoe pinnata are used worldwide for healing skin wounds. This study aimed to develop and compare two creams containing a leaf aqueous extract of K. pinnata (KP; 6%) and its major flavonoid [quercetin 3-O-α-L-arabinopyranosyl-(1→2)-α-L-rhamnopyranoside] (0.15%). Both creams were topically evaluated in a ...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2020.1817012
更新日期:2020-09-14 00:00:00
abstract::The phytochemical investigation of the stem bark of Tinospora cordifolia Miers (Menispermaceae) has afforded four new compounds, named tinosporafuranol, tinosporafurandiol, tinosporaclerodanol, and tinosporaclerodanoid, along with beta-sitosterol, and their stereostructures have been elucidated correspondingly as 4-se...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786410802435679
更新日期:2010-06-01 00:00:00
abstract::Two new eremophilanolides, sibiriolides A (1) and B (2), were isolated from the aerial parts of Xanthium sibiricum. The structures of the new compounds were identified as 4S,5R,7R,8R, 11R-2-oxo-1(10)-eremophilen-12,8-olide (1) and 4S,5R,7R,8R,11S-2-oxo-1(10)-eremophilen-12,8-olide (2) by HREIMS and NMR spectroscopic t...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786410600906780
更新日期:2006-11-01 00:00:00
abstract::New sesquiterpene glycoside, cyclodipeptide and piperidine derivative were isolated from Streptomyces sp. YIM 63342. On the basis of spectral data, their structures were determined as 3R, 5R, 6S, 7E, 9R-megastigman-7-en-3,5,6,9-tetrol-9-O-β-D-apiofuranosyl-(1→ 2)-β-D-glucopyranoside (1), cyclo (L-Pro-L-OMet) (2) and (...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2012.718776
更新日期:2013-01-01 00:00:00
abstract::Propolis is a honeybee product that has been used since ancient times because of its therapeutic effects. It can be used in the development of alternative therapies for the treatment of many diseases, and because propolis shows antibacterial action, this work was carried out in order to investigate a possible synergis...
journal_title:Natural product research
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abstract::Herein we report the regioselective synthesis of podophyllotoxin-Glycosyl triazole hybrids catalysed by Ag(I)-N-heterocyclic carbene (Ag(I)-NHC) in a short reaction time (∼30 min) at ambient conditions. In principle, it is the first report of Click alkyne-azide cycloaddition catalysed by Ag(I)-NHC catalyst and moreove...
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journal_title:Natural product research
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doi:10.1080/14786419.2019.1687477
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journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2018.1512989
更新日期:2020-05-01 00:00:00
abstract::Marsdenia tinctoria is an indigo producing plant commonly found in Borneo, Malaysia. In this present study, one new flavone kapitone (1) and three known compounds, that is 3,2'-dihydroxyflavone (2), 1-methylcyclobutene (3) and dimethyl isatoate (4) were isolated from the Malaysia Borneo M. tinctoria R. Br. (Apocynacea...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2015.1118629
更新日期:2016-07-01 00:00:00
abstract::Neuroprotection under conditions of oxygen stress of two C21 steroidal glycosides, cynsaccatol Q (1) and saccatol K (2), isolated from Cynanchum auriculatum Royle ex Wight, and their potential mechanisms were studied using the model of H2O2-induced damage on PC12 cells in this paper. Experiments showed that compounds ...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2019.1636241
更新日期:2019-07-02 00:00:00
abstract::A new isoflavone, 4'-prenyloxyvigvexin A (1) and a new pterocarpan, (6aR,11aR)-3,8-dimethoxybitucarpin B (2) were isolated from the leaves of Lonchocarpus bussei and the stem bark of Lonchocarpus eriocalyx, respectively. The extract of L. bussei also gave four known isoflavones, maximaisoflavone H, 7,2'-dimethoxy-3',4...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2018.1462179
更新日期:2019-09-01 00:00:00
abstract::A new oligostilbenoid, diptoindonesin C, has been isolated from the tree bark of Shorea pinanga Scheff., along with the two known oligostilbenoids gnetin H and hopeaphenol, and a known coumarin scopoletin. The new oligostilbenoid was moderately active against brine shrimps Artemia salina. ...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786410600761235
更新日期:2009-01-01 00:00:00
abstract::A new flavonol glycoside named Sabiapside A (1), along with four known compounds, quercetin-3-O-gentiobioside (2), camellianoside (3), isobariclisin-3-O- rutinoside (4), tsubakioside A (5), was isolated from Sabia parviflora. Their structures were elucidated by extensive spectroscopic analysis including MS, UV, IR and...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2019.1679130
更新日期:2019-10-29 00:00:00
abstract::A new β-tetralonyl glucoside, methylberchemiaside (1), along with five known compounds (2-6) were isolated from a fungus Colletotrichum sp . GDMU-1 derived from the leaves of Santalum album. Their structures were determined by detailed analysis of spectroscopic data. All compounds were tested for the inhibitory effect...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2018.1452003
更新日期:2019-02-01 00:00:00
abstract::A new triterpene saponin (1) was isolated from a methanol extract of Swartzia apetala Raddi var. glabra, together with the flavonoids mauritianin (2), kaempferol (3) and the triterpene saponin β-D-glucopyranosyl 3β-hydroxy-olean-12-en-28-oate (4). These compounds were characterised on the basis of their spectral data,...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2013.782493
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abstract::The fungus showing homology with Nodulisporium by 28S ribosomal gene sequencing, which has been discovered as an endophyte on medicinal plant Nothapodytes foetida, was found to produce 45 and 5.5 microg of camptothecin (CPT) per gram of mycelia at bioreactor and at shake flask, respectively, which was further quantifi...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786410902750944
更新日期:2009-01-01 00:00:00
abstract::A new cytisine-type alkaloid, along with five known alkaloids was obtained from the seeds of Sophora alopecuroides. Their structures were determined to be (-)-N-(2'-hydroxy-3',5'-di-tert-butyl-toluene)-cytisine (1), (-)-lupanine (2), (+)-matrine (3), (+)-sophoramine (4), (+)-lehmannine (5) and (-)-sophocarpine (6). Th...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2020.1824226
更新日期:2020-09-23 00:00:00
abstract::To search for antifungal leads, the metabolites of an insect-derived fungus Fusarium lateritium ZMT01 were investigated, providing five sesquiterpenes (1-5), including new molecules microsphaeropsisins D and E (1 and 2). The evaluated antifungal activities in vitro which are higher than the positive control triadimefo...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2021.1872569
更新日期:2021-01-15 00:00:00