Neuroprotection of two C21 steroidal glycosides from Cynanchum auriculatum against H2O2-induced damage on PC12 cells.

abstract：:There has been growing interest in the research of flavonoids due to their potential antiviral activities. Recently, some natural flavonoids have shown potential inhibitory activity against zika virus NS3-NS2B protease. In order to accelerate the drug discovery efforts using flavonoids, a Monte Carlo simulation-based ...

journal_title：Natural product research

authors： Bhargava S,Patel T,Gaikwad R,Patil UK,Gayen S

更新日期：2019-03-01 00:00:00

abstract：:A new triterpenoid saponin, silenoviscoside F (1), was isolated from the roots of Silene viscidula, together with three known saponins, dianchinenoside D (2), sinocrassuloside I (3) and sinocrassuloside II (4). The structure of compound 1 was elucidated by spectroscopic data, GC-MS and chemical methods. The structures...

journal_title：Natural product research

authors： Xu W,Fang J,Zhu Z,Wu J,Li Y

更新日期：2012-11-01 00:00:00

abstract：:Plant extracts and products have been used for centuries in traditional medicine; for most of them, in addition to the scant scientific credibility, the chemical composition and spectrum of activity are yet to be explored. To put forward this effort and to identify novel antimicrobial agents, the inhibitory activities...

journal_title：Natural product research

authors： Kumar P,Bhatt RP,Singh L,Sati OP,Khan A,Ahmad A

更新日期：2011-07-01 00:00:00

abstract：:The structure of pregnane oligoglycosides, namely rocinine (1) and marsdinine (11), which have been isolated from the chloroform soluble extract of the dried stem of Marsdenia roylei, were elucidated using MS, (1)H NMR, (13)C NMR, (1)H-(1)H COSY, HSQC and TOCSY experiments as well as chemical degradation and derivatis...

journal_title：Natural product research

authors： Gupta V,Kumar A,Khare A,Khare NK

更新日期：2009-01-01 00:00:00

abstract：:From the deep-sea-derived fungus Aspergillus candidus, one novel (1) and three known (2-4) p-terphenyl derivates were isolated. The structure of the new compound was established mainly on the basis of extensive analysis of 1D and 2D NMR data. All four isolates were tested for in vitro anti-food allergic and antitumor ...

journal_title：Natural product research

authors： Lin YK,Xie CL,Xing CP,Wang BQ,Tian XX,Xia JM,Jia LY,Pan YN,Yang XW

更新日期：2019-06-24 00:00:00

abstract：:Artemisia annua L. is an annual Eurasian desert-steppe plant. The composition of essential oils found in Artemisia annua from Russian (Buryatian) flora was analyzed in this work using gas chromatography mass-spectrometry method. Artemisia ketone, β-selinene, caryophyllene, caryophyllene oxide, germacrene D were the ma...

journal_title：Natural product research

authors： Zhigzhitzhapova SV,Dylenova EP,Gulyaev SM,Randalova TE,Taraskin VV,Tykheev ZA,Radnaeva LD

更新日期：2020-09-01 00:00:00

abstract：:Five flavonol glycosides characterised as kaempferide 3-O-(2'',3''-diacetylglucoside), kaempferide 3-O-(2''-O-galloylrhamnoside), kaempferide 3-O-(2''-O-galloylrutinoside)-7-O-alpha-rhamnoside, kaempferol 3-O-[beta-glucosyl-(1 --> 2)]-[alpha-rhamnosyl-(1 --> 6)]-beta-glucoside-7-O-alpha-rhamnoside and kaempferol 3-O-[...

journal_title：Natural product research

authors： Manguro LO,Lemmen P

更新日期：2007-01-01 00:00:00

abstract：:A phytochemical investigation of the MeOH extract of twigs and leaves of Tephrosia preussi was carried out to give a new kaempferol triglycoside, named tephrokaempferoside (1), together with five known compounds: tephrosin (2), betulinic acid (3), lupeol (4), β-sitosterol (5) and 3-O-β-d-glucopyranoside of β-sitostero...

journal_title：Natural product research

authors： Mba Nguekeu YM,Awouafack MD,Tane P,Nguedia Lando MR,Kodama T,Morita H

更新日期：2017-11-01 00:00:00

abstract：:Two new flavanone glycosides have been isolated from the water soluble part of Veratrum nigrum L., belonging to the family Lilica. The structures of 3',4'-dimethoxyl-quercitrin and 4'-methoxyl-glucotricin have been established with the aid of extensive NMR spectroscopic studies. ...

journal_title：Natural product research

authors： Li HL,Tang J,Liu RH,Zhang C,Zhang WD

更新日期：2009-01-01 00:00:00

abstract：:This study is designed to examine the chemical composition and antioxidant activity of the essential oil of Vitex megapotamica. Gas chromatography-mass spectrometry analysis resulted in the detection of 27 components, representing 92.36% of the total oil composition. The main components in the oil were butylated hydro...

journal_title：Natural product research

authors： de Brum TF,Boligon AA,Frohlich JK,Schwanz TG,Zadra M,Piana M,Froeder AL,Athayde ML

更新日期：2013-04-01 00:00:00

abstract：:A new eremophilane sesquiterpene, capnodiumone (1), along with five known eremophilane sesquiterpenes (2-6) and eight other compounds (7-14), have been isolated from a mangrove-associated fungus Capnodium sp. SZ-F22. The chemical structures were elucidated on the basis of extensive spectroscopic analysis. The broth ex...

journal_title：Natural product research

authors： He H,Ma Z,Wang Q,Liu Y,Xu H

更新日期：2016-07-01 00:00:00

abstract：:The aerial parts of Baccharis dracunculifolia (BdE) is used in the Brazilian folk medicine to treat inflammatory conditions. Here we examined the ability of free and liposomal BdE to modulate reactive oxygen species generation in human neutrophils in vitro and zymosan-induced acute joint inflammation in Wistar rats. W...

journal_title：Natural product research

authors： de Figueiredo-Rinhel ASG,de Andrade MF,Landi-Librandi AP,Azzolini AECS,Kabeya LM,Bastos JK,Lucisano-Valim YM

更新日期：2019-09-01 00:00:00

abstract：:A new isoflavone glycoside, named 3'-hydroxytectorigenin-7-O-β-D-xylosyl-(1→6)-β-D-glucopyranoside (1) was isolated from the flowers of Pueraria montana var. lobata (Willd.) Sanjappa & Pradeep. The structure of compound 1 was characterised by HR-ESI-MS and NMR spectroscopic methods. In radical scavenging activity test...

journal_title：Natural product research

authors： Ma Y,Shang Y,Zhong Z,Zhang Y,Yang Y,Feng J,Wei Z

更新日期：2019-08-21 00:00:00

abstract：:A new monoterpenoid indole alkaloid, 10-methoxyakuammidine (1), together with four known alkaloids (2-5), were isolated from the stems and leaves of Ochrosia elliptica. The structure of 1 was elucidated by extensive spectroscopic methods and the known compounds were identified by comparisons with data reported in the ...

journal_title：Natural product research

authors： Chen AH,Liu QL,Ma YL,Jiang ZH,Tang JY,Liu YP,Chen GY,Fu YH,Xu W

更新日期：2017-07-01 00:00:00

abstract：:Cinobufagin was one of the important cardenolidal steroids and a major component of Chan'Su, a famous traditional Chinese medicine. The urinary metabolites of cinobufagin after single oral doses of 25 mg kg⁻¹ in rats were investigated. Eleven metabolites were isolated and purified by liquid-liquid extraction, open-col...

journal_title：Natural product research

authors： He X,Hu H,Wu Y,Zeng X

更新日期：2012-01-01 00:00:00

abstract：:Artemisia alba Turra (Asteraceae) is an Euro-Mediterranean plant used in Veneto (North-East of Italy) as traditional medicine for the treatment of various diseases. A. alba is a taxonomically problematic species, characterised by common polymorphism leading to a quite high variability in secondary metabolites content....

journal_title：Natural product research

authors： Peron G,Baldan V,Sut S,Faggian M,Roccabruna L,Zanini D,Manzini P,Maggi F,Dall'Acqua S

更新日期：2017-08-01 00:00:00

abstract：:A series of (E)-1-(4-alkyloxyphenyl)-3-(hydroxyphenyl)-prop-2-en-1-one have been successfully synthesised via Claisen-Schmidt condensation. The synthesised chalcone derivatives consisted of hydroxyl groups at either ortho, meta or para position and differed in the length of the alkyl groups, C (n) H(2) (n) (+1,) whe...

journal_title：Natural product research

authors： Ngaini Z,Fadzillah SM,Hussain H

更新日期：2012-01-01 00:00:00

abstract：:The aim of this work was to provide a characterisation of volatile constituents from different commercial batches of henna (Lawsonia inermis) leaves of different geographic origin. Headspace solid-phase microextraction (HS-SPME) coupled with gas chromatography-mass spectrometry (GC-MS) was used for the purpose. A tota...

journal_title：Natural product research

authors： Mengoni T,Peregrina DV,Censi R,Cortese M,Ricciutelli M,Maggi F,Di Martino P

更新日期：2016-01-01 00:00:00

abstract：:A new HPLC-DAD method was developed and validated for simultaneous determination of six main phenylethanoid glycosides (calceolarioside D, neocalceolarioside D, verbascoside, isoverbascoside, leucoseptoside A and martynoside) in the aerial parts of four Scutellaria L. taxa from flora of Turkey. All standard compounds ...

journal_title：Natural product research

authors： Bardakci H,Türköz Acar E,Kırmızıbekmez H

更新日期：2019-07-01 00:00:00

abstract：:Penicillium polonicum MCCC3A00951 is a fungus with influenza neuraminidase (NA) inhibition activity derived from a sediment of the mangrove forest of Zhangjiangkou in Fujian province, China. Chemical investigation on an ethyl acetate extract of its fermentation led to the isolation of a new compound, 7-hydroxy-3,10-de...

journal_title：Natural product research

authors： Liu SZ,He FM,Bin YL,Li CF,Xie BY,Tang XX,Qiu YK

更新日期：2020-09-14 00:00:00

abstract：:Trichosanthes dioica Roxb. (Cucurbitaceae), named 'pointed gourd' in English, is a dioecious climber grown in India. This study was aimed at evaluating the laxative activity of the aqueous extract of T. dioica root (TDA) in Swiss albino mice. The laxative activity of TDA (100 and 200 mg kg(-1) body weight per os) was ...

journal_title：Natural product research

authors： Bhattacharya S,Haldar PK

更新日期：2012-01-01 00:00:00

abstract：:A new cyclopeptide alkaloid, sativanine-M (1), together with known alkaloid nummularine-P have been isolated from the stem bark of Zizyphus sativa and identified by spectral analysis. ...

journal_title：Natural product research

authors： Pandey MB,Singh AK,Singh VP,Pandey VB

更新日期：2008-02-15 00:00:00

abstract：:From the fermentation broths of the actinomycete Micromonospora rhodorangea, four anthraquinone derivatives (1-4) were isolated, of which 2-ethyl-1,8-dihydroxy-3-methyl-anthraquinone (1) and 3,8-dihydroxy-1-propylanthraquinone (3) were determined as new compounds. Their structures were established by using extensive s...

journal_title：Natural product research

authors： Xue CM,Tian L,Lin WH,Deng ZW

更新日期：2009-01-01 00:00:00

abstract：:Phytochemical investigation of the methanol extract of Euchresta formosana resulted in the isolation of thirty-four compounds. Compounds 1, 3-12, 15, 27, 29 and 32-24 were isolated from this species for the first time. These compounds were identified by spectral analyses and tested for antiplatelet aggregation and ant...

journal_title：Natural product research

authors： Lo WL,Wu CC,Chang FR,Wang WY,Khalil AT,Lee KH,Wu YC

更新日期：2003-04-01 00:00:00

abstract：:Essential oils from aerial parts of Senecio nutans, Senecio viridis, Tagetes terniflora and Aloysia gratissima were analysed by GC-MS and their antifungal activities were assayed on toxigenic Fusarium and Aspergillus species. Sabinene (27.6 ± 0.1%), α-phellandrene (15.7 ± 0.3%), o-cymene (9.6 ± 0.2%) and β-pinene (6.1...

journal_title：Natural product research

authors： Galvez CE,Jimenez CM,Gomez ALA,Lizarraga EF,Sampietro DA

更新日期：2020-05-01 00:00:00

abstract：:A new phthalide derivative, xylarphthalide A (1), along with two known compounds (-)-5-carboxylmellein (2) and (-)-5-methylmellein (3), were isolated from the endophytic fungus Xylaria sp. GDG-102 cultured from the Chinese medicinal plant Sophora tonkinensis. Their structures were identified by MS and NMR experiments,...

journal_title：Natural product research

authors： Zheng N,Yao F,Liang X,Liu Q,Xu W,Liang Y,Liu X,Li J,Yang R

更新日期：2018-04-01 00:00:00

abstract：:The subject of this present work is a group of nine historical pictures shot in Palermo by the Sicilian photographer E. Interguglielmi in 1912. They are nine matte-collodion prints mounted on the original cardboard supports and all of them show foxing stains affecting the paper surface. In order to characterise the ch...

journal_title：Natural product research

authors： Modica A,Bruno M,Di Bella M,Alberghina MF,Brai M,Fontana D,Tranchina L

更新日期：2019-04-01 00:00:00

abstract：:Plants endue a key role against illnesses caused by oxidative stress. These attributes are frequently associated with polyphenolic compounds. However, presence and concentration of secondary metabolites are affected by abiotic factors. The in vitro culture techniques can solve these drawbacks. Peppers can be a suitabl...

journal_title：Natural product research

authors： Fidemann T,de Araujo Pereira GA,Bossard Nascimento L,Moraes MC,Bertão MR,da Silva RMG,Fernández Núñez EG

更新日期：2018-05-01 00:00:00

abstract：:A new denudatine-type C20-diterpenoid alkaloid, pubesine (1), along with seven known diterpenoid alkaloids, altaconitine (2), 14-benzoylaconine (3), spicatine A (4), 14-benzoylaconine-8-palmitate (5), 14-O-acetylsenbusine A (6), senbusine A (7) and 14-acetylneoline (8) were isolated from the whole plant of Aconitum so...

journal_title：Natural product research

authors： Chen L,Shan L,Xu W,Zhang J,Huang S,Zhou X

更新日期：2017-03-01 00:00:00

abstract：:Three new sesquiterpenes: 4-acrylic-6-methyl-α-tetralone (1), ainsliaea acid A (2) and ainsliaea acid B (3), together with 8 known compounds (4-11) were isolated from the whole herb of Ainsliaea glabra and their structures were established by means of 1D and 2D NMR spectroscopy and HR-ESIMS. Compounds 1-6 were tested ...

journal_title：Natural product research

authors： Chen YP,Tong C,Lu WQ,Shen YH,Wu ZJ,Chen WS

更新日期：2019-01-01 00:00:00