Simultaneous quantification of six phenylethanoid glycosides in some Turkish Scutellaria species by a new HPLC-DAD method.

abstract：:One new limonoid, named siamensinolide (1), together with two known limonoids (2 and 3) and eight carbazole alkaloids (4-11) were isolated from the twigs of Chalcas siamensis Tanaka. Their structures were elucidated by spectroscopic methods, mainly 1D and 2D NMR spectroscopy. O-methylclausenolide (2) displayed strong ...

journal_title：Natural product research

authors： Boonyaketgoson S,Rukachaisirikul V,Phongpaichit S,Trisuwan K

更新日期：2020-05-25 00:00:00

abstract：:The chemical investigation of the extract of the dried leaves of Rauvolfia caffra (Sond) (synonym Rauvolfia macrophylla) (Apocynaceae) led to isolation of a new glycoside derivative, rauvolfianine (1) as well as six known compounds: oleanolic acid (2), sitosterol-3-O-β-D-glucopyranoside (3), betulinic acid (4), vellos...

journal_title：Natural product research

authors： Ebeh Messanga R,Dominique Serge NB,Abouem A Zintchem A,Norbert MNI,Esther Del Florence MN,Patrick Hervé BD,Maximilienne Ascension N,Alex De Théodore A,Dieudonné Emmanuel P,Christian G B,Koert U

更新日期：2018-08-01 00:00:00

abstract：:A novel alkaloid named oleraciamide C (1), with six known compounds, hydroxydihydrobovolide (2), uracil (3), catechol (4), 4-aminophenol (5), vanillic acid (6) as well as 3-hydroxypyridine (7), were isolated from Portulaca oleracea L. Additionally, hydroxydihydrobovolide (2), 4-aminophenol (5), 3-hydroxypyridine (7) w...

journal_title：Natural product research

authors： Xu L,Ying Z,Wei W,Hao D,Wang H,Zhang W,Li C,Jiang M,Ying X,Liu J

更新日期：2017-04-01 00:00:00

abstract：:Two new iridoids namely valerialloside A and valerianoside A (1 and 2) along with five known compounds (3-7) were isolated from the roots of Valeriana jatamansi Jones. The structure of new compounds were determined using 1D and 2D NMR including 1H-1H COSY, HSQC, HMBC and NOESY spectroscopic techniques. ...

journal_title：Natural product research

authors： Maurya AK,Kumar A,Agnihotri VK

更新日期：2020-12-09 00:00:00

abstract：:Studies on the stem of Garcinia mangostana have led to the isolation of one new xanthone mangosharin (1) (2,6-dihydroxy-8-methoxy-5-(3-methylbut-2-enyl)-xanthone) and six other prenylated xanthones, alpha-mangostin (2), beta-mangostin (3), garcinone D (4), 1,6-dihydroxy-3,7-dimethoxy-2-(3-methylbut-2-enyl)-xanthone (5...

journal_title：Natural product research

authors： Ee GC,Daud S,Taufiq-Yap YH,Ismail NH,Rahmani M

更新日期：2006-10-01 00:00:00

abstract：:Novel derivatives of 4-oxo-3-methylcytisine with phenyl moiety bonded to starting molecule through various spacers were obtained from the 9-amino, -halo, -formyl and 11-halo precursors by reductive alkylation of amines, generation of amide, as well as thio- and carboxamide functions, cross-coupling reactions, aldehyde...

journal_title：Natural product research

authors： Tsypysheva I,Petrova P,Koval'skaya A,Lobov A,Sapozhnikova T,Makara N,Gabdrakhmanova S,Zarudii F

更新日期：2021-01-01 00:00:00

abstract：:The leaves of Alchornea floribunda and Alchornea cordifolia are used traditionally as topical anti-inflammatory agents. In this study, two highly lipophilic fractions AFLF and ACLF isolated from A. floribunda and A. cordifolia leaves respectively were investigated for topical anti-inflammatory effects using xylene-ind...

journal_title：Natural product research

authors： Okoye FB,Osadebe PO,Nworu CS,Okoye NN,Omeje EO,Esimone CO

更新日期：2011-12-01 00:00:00

abstract：:The cholesteryl ester transfer protein (CETP), inhibition of which assists in maintaining a high level of high-density lipoprotein cholesterol in the blood, is a target for anti-atherosclerosis treatments. Orange monascus pigment was produced by a Monascus species in a 5 L jar fermenter and various derivative compound...

journal_title：Natural product research

authors： Jang H,Choe D,Shin CS

更新日期：2014-01-01 00:00:00

abstract：:A new protopine alkaloid, protomexicine and a new isoflavonoid, mexitin, together with 8-methoxydihydrosanguinarine, 13-oxoprotopine, rutin and quercetrin have been isolated from the aerial part of the methanolic extract of Argemone mexicana. The structures of these compounds have been established by various spectral ...

journal_title：Natural product research

authors： Singh S,Pandey VB,Singh TD

更新日期：2012-01-01 00:00:00

abstract：:Acetylcholinesterase (AChE) inhibitors have been used for the symptomatic treatment of Alzheimer's disease. Eleven whole plants from Panama belonging to the Lycopodiaceae family have been screened for their anticholinesterase inhibitory and antioxidant activities by a thin-layer chromatography (TLC) bioautography meth...

journal_title：Natural product research

authors： Calderón AI,Simithy-Williams J,Sanchez R,Espinosa A,Valdespino I,Gupta MP

更新日期：2013-03-01 00:00:00

abstract：:In order to identify genes related to Taxol biosynthesis, the mRNA differential display method was employed to compare mRNA populations from suspension cultured Taxus chinensis cells before and after beginning to produce Taxol. From a total display of about 4000 PCR products, 104 were derived from cells during the Tax...

journal_title：Natural product research

authors： Hu G,Fan T,Mei X

更新日期：2004-08-01 00:00:00

abstract：:A new triterpene saponin (1) was isolated from a methanol extract of Swartzia apetala Raddi var. glabra, together with the flavonoids mauritianin (2), kaempferol (3) and the triterpene saponin β-D-glucopyranosyl 3β-hydroxy-olean-12-en-28-oate (4). These compounds were characterised on the basis of their spectral data,...

journal_title：Natural product research

authors： de Araújo MF,Curcino Vieira IJ,Sant'Anna CM,da Silva DR,Vitorino Maia AI,Braz-Filho R,Vieira-da-Motta O,Mathias L

更新日期：2013-10-01 00:00:00

abstract：:Herein we report the regioselective synthesis of podophyllotoxin-Glycosyl triazole hybrids catalysed by Ag(I)-N-heterocyclic carbene (Ag(I)-NHC) in a short reaction time (∼30 min) at ambient conditions. In principle, it is the first report of Click alkyne-azide cycloaddition catalysed by Ag(I)-NHC catalyst and moreove...

journal_title：Natural product research

authors： Nerella S,Kankala S,Gavaji B

更新日期：2021-01-01 00:00:00

abstract：:In the present study, evaluation of the antiproliferative activity of Pachypodium lamerei Drake leaves (family Apocyaceae) against human breast cancer cell lines MDA-MB-231 was done for the total methanolic extract, crude alkaloidal mixture and ursolic acid using the MTT colorimetric assay. The methanolic extract show...

journal_title：Natural product research

authors： Mina SA,Mohamed SA,Melek FR,Abd El-Khalik SM

更新日期：2020-05-01 00:00:00

abstract：:The investigation on the stems and leaves of Clausena lenis led to the isolation of a previously undescribed carbazole alkaloid, clausenalenine A (1), along with seven known analogues (2-8). The structure of 1 was elucidated based on comprehensive spectroscopic analyses and the known compounds were identified by compa...

journal_title：Natural product research

authors： Yan G,Li YJ,Zhao YY,Guo JM,Zhang WH,Zhang MM,Fu YH,Liu YP

更新日期：2019-09-16 00:00:00

abstract：:A new chalcone named as balanochalcone (1) together with eight known compounds, methyl caffeate (2), β-hydroxydihydrochalcone (3), methyl gallate (4), dimethyl-6,9,10-trihydroxybenzo[kl]xanthene-1,2-dicarboxylate (5), p-coumaric acid (6), quercetin (7), scopoletin (8) and pinoresinol (9) have been isolated from the et...

journal_title：Natural product research

authors： Quang DN,So TC,Thanh NTP,Hoa LTP,Dien PH,Luong TM,Tung NQ,Long LD,Dai TD,Tien NQ

更新日期：2018-04-01 00:00:00

abstract：:Two new flavans, named (2S)-2',4'-dihydroxy-7-methoxy-8-methylflavan (1) and (2S)-2'-hydroxy-4',7-dimethoxy-8-methylflavan (2) were isolated from the roots of Dianella ensifolia. Their structures were elucidated by extensive spectroscopic measurements and comparison with data reported in literatures. Compounds 1 and 2...

journal_title：Natural product research

authors： Tang BQ,Huang SS,Liang YE,Sun JB,Ma Y,Zeng B,Lee SM,Lu JL

更新日期：2017-07-01 00:00:00

abstract：:Two new compounds, identified as 3-(2-hydroxybenzyl)-6,8-dimethoxy-4H-chromen-4-one (1), named oleracone J and 3-(2-hydroxybenzyl)-6,8-dimethoxychroman-4-one (2), named oleracone K, were isolated from Portulaca oleracea L., and the structures of them were determined by spectroscopy, including one-dimensional and two-d...

journal_title：Natural product research

authors： Duan Y,Ying Z,Zhang M,Ying X,Yang G

更新日期：2020-09-03 00:00:00

abstract：:A new furostanol saponin, (25R)-26-O-(α-d-glucopyranosyl)-(1→2)-α-l-rhamnopyranosyl-furost-5-ene-3β, 22α, 26-triol-3-O-α-d-glucopyranoside (1), together with four known compounds 2-5 were isolated from the ethanolic extract of the stems of Dendrobium chrysanthum Lindl. The structures of these new compounds were identi...

journal_title：Natural product research

authors： Yang C,Lin W,Zhao L,Cai J

更新日期：2019-09-01 00:00:00

abstract：:Two new monoterpene glucosides: xanmonoter A (1) and xanmonoter B (2) were isolated from Xanthium strumarium. Their structures were elucidated on the basis of 1D and 2D NMR, MS and CD analysis. Compounds 1 and 2 were tested for their anti-inflammatory activity with IC50 values of 17.4, 22.1 μM, respectively. ...

journal_title：Natural product research

authors： Jiang H,Xing X,Yan M,Guo X,Yang L,Yang L

更新日期：2019-12-01 00:00:00

abstract：:Among phenolic compounds, Agave americana L. extract contained puerarin (38.4%) and p-coumaric acid (12.29%) (pCa). From the Lineweaver-Burk plots, pCa and puerarin demonstrated a competitive and a non competitive inhibitions towards human α-amylase activity, respectively. PCa exhibited a higher human inhibitory activ...

journal_title：Natural product research

authors： Sahnoun M,Bejar S,Daoud L,Ayadi L,Brini F,Saibi W

更新日期：2019-03-01 00:00:00

abstract：:Using a bioactivity-guided fractionation procedure, five cembranolides, 11-epi-sinulariolide acetate (1), 11-dehydrosinulariolide (2), sinulariolide (3), dihydrosinularin (4), and 3,4:8,11-bisepoxy-7-acetoxycembra-15(17)-en-1,12-olide (5), along with two nucleosides, 2'-deoxyadenosine and thymidine, were isolated from...

journal_title：Natural product research

authors： Hsieh PW,Chang FR,McPhail AT,Lee KH,Wu YC

更新日期：2003-12-01 00:00:00

abstract：:Flavonoids have always attracted much attention due to their reversal activity on multidrug resistance (MDR). Eight flavonoids isolated from traditional Chinese medicine Sophora alopecuroides L. were applied to test their effect on MDR associated protein 1 (MRP1) through the established predicting assay. Three flavono...

journal_title：Natural product research

authors： Ni K,Yang L,Wan C,Xia Y,Kong L

更新日期：2014-01-01 00:00:00

abstract：:Triterpene saponins are throught to be potential anti-tumour agents in many cell types. This study aims to evaluate the cytotoxic activity and mechanism of a triterpene saponin, macranthoside B (MB), isolated from Lonicera macranthoides Hand.-Mazz. (Caprifoliaceae). A cell viability assay showed that MB inhibited cell...

journal_title：Natural product research

authors： Guan F,Shan Y,Zhao X,Zhang D,Wang M,Peng F,Xia B,Feng X

更新日期：2011-02-01 00:00:00

abstract：:The ethanolic extract of the fruits of Momordica dioica was studied for its protective and curative effect against gentamicin-induced acute renal injury in albino rats of both sexes. Gentamicin intoxicated group showed significant increase in blood urea (69.48 +/- 4.34) and serum creatinine (3.017 +/- 0.208) from norm...

journal_title：Natural product research

authors： Jain A,Singhai AK

更新日期：2010-09-01 00:00:00

abstract：:This work reports the phytochemical profile and insecticidal properties of Perovskia artemisioides Boiss essential oil (PAEO) collected in Baluchestan, Iran. Totally, twenty-six substances were identified with 1,8-cineole (25.81%), geranyl acetate (13.00%) and linalool (10.21%) as dominant chemical metabolites by GC-M...

journal_title：Natural product research

authors： Sadeghi Z,Alizadeh Z,Khorrami F,Norouzi S,Moridi Farimani M

更新日期：2020-08-26 00:00:00

abstract：:As part of continuing our research on diverse C-7 derivatives of camptothecin (CPT), 16 CPT derivatives bearing piperazinyl-thiourea chemical scaffold and different substituent groups have been designed, synthesized and evaluated in vitro for cytotoxicity against five tumor cell lines (A-549, MDA-MB-231, MCF-7, KB and...

journal_title：Natural product research

authors： Song ZL,Yang GZ,Li JC,Liu YQ,Yang CJ,Goto M,Zhang ZJ,Morris-Natschke SL,Liu H,Lee KH

更新日期：2020-07-01 00:00:00

abstract：:Four xanthones were isolated from Gentianopsis paludosa Ma and were identified by modern spectroscopic methods. Cytotoxicity of the four xanthones was tested on HepG2 cells and HL-60 cells by sulphorhodamine B (SRB) assay. Clonogenic survival assay, trypan blue exclusion method, AO/EB staining and DNA fragmentation as...

journal_title：Natural product research

authors： Ding L,Liu B,Zhang SD,Hou Q,Qi LL,Zhou QY

更新日期：2011-04-01 00:00:00

abstract：:A new germacrenolide (1) and fourteen known terpenoids (2-15) were isolated from the barks of Magnolia maudiae (Dunn) Figlar (Magnoliaceae). The structure of (7αH,11βH)-2α,8α-dihydroxy-4α,5β-epoxy-germacr-1(10)-en-6α,12-olide (1) was elucidated by physical and spectroscopic data analysis, including 1D, 2D NMR and HR-E...

journal_title：Natural product research

authors： Xianjin S,Sha S,Qi M,Zhang Z,Yang Y,Wu H,Li L,Wang W,Huang A

更新日期：2018-07-01 00:00:00

abstract：:One new briarane-type diterpenoid, dichotellide V (1), along with four known analogues, gemmacolide N (2), dichotellide J (3), junceelin A (4) and junceellolide A (5), was isolated from the South China Sea gorgonian Dichotella gemmacea. All of the isolated compounds (1-5) were established by comprehensive analysis of ...

journal_title：Natural product research

authors： Sun JF,Yang B,Zhou XF,Yang XW,Wang L,Liu Y

更新日期：2015-01-01 00:00:00