Incorporation of Baccharis dracunculifolia DC (Asteraceae) leaf extract into phosphatidylcholine-cholesterol liposomes improves its anti-inflammatory effect in vivo.

abstract：:One new sesqui-neolignan compound, namely, sesqui-illisimonan A (1), one new neolignan, illisimonan A (2), and one new phenylpropanoid compound, illisimoid A (3) were isolated from the fruits of Illicium simonsii Maxim. The structures and absolute configurations of these compounds were determined by extensive spectros...

journal_title：Natural product research

authors： Zhuang PY,Chen MH,Wang YN,Wang XX,Feng YJ,Zhang DY

更新日期：2018-10-01 00:00:00

abstract：:Phytochemical investigation of the methylenechloride/methanol extract of the aerial parts of Stachys aegyptiaca afforded a new neoclerodane-type diterpene with a new side chain 1, in addition to two known diterpenes 2 and 3 and a known flavonoid glycoside 4. The structures of the compounds were determined by comprehen...

journal_title：Natural product research

authors： Mohamed Ael-H,Mohamed NS

更新日期：2014-01-01 00:00:00

abstract：:Oregano (Origanum vulgare L.) is a common aromatic plant used in Mediterranean and Asian Regions for treating respiratory diseases, painful menstruation, rheumatoid arthritis, etc. Recently its role as an anticancer plant has been suggested, although oregano has been never evaluated into adrenocortical tumour cell mod...

journal_title：Natural product research

authors： Rubin B,Manso J,Monticelli H,Bertazza L,Redaelli M,Sensi F,Zorzan M,Scaroni C,Mian C,Iacobone M,Armanini D,Bertolini C,Barollo S,Boscaro M,Pezzani R

更新日期：2019-06-01 00:00:00

abstract：:Chemical investigation of the stems of Epigunum griffithianum led to the isolation and identification of a new triterpenoid saponin (1) and two known compounds (epigynosides A (2) and B (3)). These structures were elucidated by means of spectroscopic analysis (1D and 2D NMR, MS, UV, IR) as well as comparison with the ...

journal_title：Natural product research

authors： Wang Q,Li WY,Wang YD

更新日期：2020-05-01 00:00:00

abstract：:Two phytotoxic furan derivatives were isolated, together with the well-known fungal and plant phytotoxin tyrosol, from the culture filtrates of Stilbocrea macrostoma. This fungal pathogen isolated from Quercus brantii trees induced wood necrosis and decline symptoms on the host plant in Iran. The two furan derivatives...

journal_title：Natural product research

authors： Di Lecce R,Bashiri S,Masi M,Alioto D,Tuzi A,Abdollahzadeh J,Evidente A

更新日期：2020-10-05 00:00:00

abstract：:Azadirachtin-A (Aza-A, figure 1) was subjected to a variety of synthetic transformations and the antifeedant activity and toxicity of the azadirachtin derivatives were assessed against second instar larvae Spodoptera litura on castor leaves in comparison with the crude material containing 9.14% Aza-A, as well as relat...

journal_title：Natural product research

authors： Deota PT,Upadhyay PR

更新日期：2005-07-01 00:00:00

abstract：:First total synthesis of carpatamide-A 7a, cytotoxic arylamine derivative isolated from marine derived Streptomyces sp., was achieved in twelve steps with overall yield of 24% with seven longest linear steps. In the penultimate step, dienoic acid 13 and an amino-phenylpropionic acid methyl ester core 21 were coupled t...

journal_title：Natural product research

authors： Burman RP,Gupta S,Bhatti J,Verma K,Rajak D,Gill MS

更新日期：2019-04-01 00:00:00

abstract：:Investigation of the aerial parts of Vernonia leopoldii (Sch. Bip.) Vatke afforded a new lanostane-type triterpene along with known hirsutinolide-type sesquiterpene lactones and flavonoid glycosides, all are identified for the first time in this species. The new compound was identified as lanost-3β, 23S-dihydroxy-22(3...

journal_title：Natural product research

authors： Marzouk AM,Abd Elhalim OB

更新日期：2016-01-01 00:00:00

abstract：:Medicinal plants have been the main remedy to treat various ailments for a long time and nowadays, many drugs have been developed from traditional medicine. This paper reviews some medicinal plants and their main constituents which possess anti-inflammatory activities useful for curing joint inflammation, inflammatory...

journal_title：Natural product research

authors： Maione F,Russo R,Khan H,Mascolo N

更新日期：2016-06-01 00:00:00

abstract：:A new denudatine-type C20-diterpenoid alkaloid, pubesine (1), along with seven known diterpenoid alkaloids, altaconitine (2), 14-benzoylaconine (3), spicatine A (4), 14-benzoylaconine-8-palmitate (5), 14-O-acetylsenbusine A (6), senbusine A (7) and 14-acetylneoline (8) were isolated from the whole plant of Aconitum so...

journal_title：Natural product research

authors： Chen L,Shan L,Xu W,Zhang J,Huang S,Zhou X

更新日期：2017-03-01 00:00:00

abstract：:The chemical composition of the solvent extracted fixed oil of black cumin (Nigella sativa L.) seeds was determined by capillary GC and GC/MS. Thirty-two fatty acids (99.9%) have been identified in the fixed oil. The major fatty acids were linoleic acid (50.2%), oleic acid (19.9%), margaric acid (10.3%), cis-11,14-eic...

journal_title：Natural product research

authors： Amin S,Mir SR,Kohli K,Ali B,Ali M

更新日期：2010-07-01 00:00:00

abstract：:A new γ-pyrone derivative, acrepyrone A (1), and three known sorbicillinoids, trichodimerol (2), dihydrotrichodimerol (3) and tetrahydrotrichodimerol (4) were isolated from an endophytic fungus, Acremonium citrinum SS-g13, harboured in the roots of the Chinese medicinal plant Fructus mori. Their structures were determ...

journal_title：Natural product research

authors： Peng XP,Li G,Ji LX,Li YX,Lou HX

更新日期：2020-04-01 00:00:00

abstract：:Triterpene saponins are throught to be potential anti-tumour agents in many cell types. This study aims to evaluate the cytotoxic activity and mechanism of a triterpene saponin, macranthoside B (MB), isolated from Lonicera macranthoides Hand.-Mazz. (Caprifoliaceae). A cell viability assay showed that MB inhibited cell...

journal_title：Natural product research

authors： Guan F,Shan Y,Zhao X,Zhang D,Wang M,Peng F,Xia B,Feng X

更新日期：2011-02-01 00:00:00

abstract：:Four fractions were prepared from the crude extract of Caesalpinia minax Hance and the inhibitory activity of nitric oxide (NO) production release of RAW 264.7 cells stimulated by lipopolysaccharide (LPS) was evaluated. The ethyl acetate (EtOAc) fraction showed obvious inhibitory effect. Bioassay-guided fractionation ...

journal_title：Natural product research

authors： Liu Q,Bai B,Yang DP,Peng SY,Zhu LP,Luo MH,Zhao ZM

更新日期：2018-04-01 00:00:00

abstract：:A new polyoxygenated briarane-type diterpenoid, briarenol A (1), has been isolated from a gorgonian coral belonging to the genus Briareum. The structure, including the relative stereochemistry of briarane 1, was elucidated by the interpretation of spectral data. The configuration of 1 was further supported by molecula...

journal_title：Natural product research

authors： Sung PJ,Hu WP,Fang LS,Fan TY,Wang JJ

更新日期：2005-10-01 00:00:00

abstract：:A new benzophenone glycoside, mitraphenone A (1), together with three known compounds (2-4) were isolated from the leaves of the traditionally used medicinal plant Mitracarpus villosus (Rubiaceae) collected in Nigeria. A combination of one- and two-dimensional NMR spectroscopic and mass spectrometric measurements were...

journal_title：Natural product research

authors： Ngwoke KG,Orame N,Liu S,Okoye FBC,Daletos G,Proksch P

更新日期：2017-10-01 00:00:00

abstract：:Camptothecin (CPT), the derivatives of which are used clinically for the treatment of metastatic colon cancer, is isolated from intact plants that can be subjected to environmental fluctuations. In vitro cultures may be an alternate and continuous source for year-round production of CPT. Since CPT production by undiff...

journal_title：Natural product research

authors： Kamble S,Gopalakrishnan R,Eapen S

更新日期：2011-10-01 00:00:00

abstract：:Santolina insularis is a Sardinian endemism that is widely used in traditional medicine. The essential oil was obtained with a yield of 2.7% and is mainly characterized by β-phellandrene (22.6%), myrcene (11.4%) and artemisia ketone (7.6%). The oil significantly reduced NO production without affecting macrophages viab...

journal_title：Natural product research

authors： Alves-Silva JM,Piras A,Porcedda S,Falconieri D,Maxia A,Gonçalves MJ,Cruz MT,Salgueiro L

更新日期：2020-06-04 00:00:00

abstract：:A megastigmane sulphoglycoside together with three phenolic compounds were isolated from the water-soluble fraction of the pericarps of Garcinia mangostana. The structure of the new compound was determined as 4-O-sulpho-β-d-glucopyranosyl abscisate (1) by spectroscopic data. Proanthocyanidin A2 (2) showed potent α-glu...

journal_title：Natural product research

authors： Tran TH,Le Huyen T,Tran TM,Nguyen TA,Pham TB,Nguyen Tien D

更新日期：2016-07-01 00:00:00

abstract：:The aim of the present study was to evaluate the phenolic contents in capsule and root methanolic extracts of Euphorbia retusa followed by identification of phenolic on capsule extracts through high-performance liquid chromatography (HPLC- DAD) for the first time. Likewise, the antioxidant activity of both extracts wa...

journal_title：Natural product research

authors： Lahmadi S,Belhamra M,Karoune S,Imad K,Bensouici C,Kechebar MSA,Halis Y,Ksouri R

更新日期：2020-12-01 00:00:00

abstract：:Bioassay guided chemical investigation of the gorgonian Pacifigorgia senta led to the discovery of a new 19-oxygenated steroid, cholesta-5,24-diene-3β,7β,19-triol (1), as well as three known steroids (2-4). The structure of 1 was determined by extensive spectroscopic analysis, including NMR and MS spectra. All of the ...

journal_title：Natural product research

authors： Chen M,Han L,Zhang XL,Wang CY

更新日期：2016-06-01 00:00:00

abstract：:The phytochemical investigation of the stem bark of Tinospora cordifolia Miers (Menispermaceae) has afforded four new compounds, named tinosporafuranol, tinosporafurandiol, tinosporaclerodanol, and tinosporaclerodanoid, along with beta-sitosterol, and their stereostructures have been elucidated correspondingly as 4-se...

journal_title：Natural product research

authors： Ahmad F,Ali M,Alam P

更新日期：2010-06-01 00:00:00

abstract：:The anti-enteroviral activity of three stilbenoids isolated from the leaves of Macaranga barteri was investigated using the cytopathic effect reduction assay. The stilbenes were inactive against echovirus E13 but showed activity against echoviruses E7 and E19. In particular, vedelianin (2), schweinfurthin G (3) and ma...

journal_title：Natural product research

authors： Segun PA,Ogbole OO,Akinleye TE,Faleye TOC,Adeniji AJ

更新日期：2019-07-25 00:00:00

abstract：:Propolis is a honeybee product that has been used since ancient times because of its therapeutic effects. It can be used in the development of alternative therapies for the treatment of many diseases, and because propolis shows antibacterial action, this work was carried out in order to investigate a possible synergis...

journal_title：Natural product research

authors： Orsi RO,Fernandes A Jr,Bankova V,Sforcin JM

更新日期：2012-01-01 00:00:00

abstract：:The present work describes the metabolites produced by a strain identified as Streptomyces youssoufiensis, whose secondary metabolites profile has not been studied so far. The crude ethyl acetate extract was analyzed by high performance liquid chromatography-electrospray ionization mass spectrometry, leading to the de...

journal_title：Natural product research

authors： Leulmi N,Sighel D,Defant A,Khenaka K,Boulahrouf A,Mancini I

更新日期：2019-01-01 00:00:00

abstract：:Epicatechin (EC) is the most effective compound in Euonymus alatus (Thunb.)Sieb, and possesses a series of benefits, including anti-inflammatory, antioxidant, antiobesity and anticancer effects. In this study, we investigated the protective effects of EC in Acetaminophen(N-acetyl-p-aminophenol, APAP)-induced acute liv...

journal_title：Natural product research

authors： Wu H,Xie Y,Xu Y,Hu Z,Wan X,Huang H,Huang D

更新日期：2020-03-01 00:00:00

abstract：:Since the last decades, socio-economic changes have a key role on eating habits affecting the nutritional status and health of people, in particular children and adolescents. The aim of this study was to compare the diet of student population both normal weight and overweight and obese in order to understand their eat...

journal_title：Natural product research

authors： Metro D,Tardugno R,Papa M,Bisignano C,Manasseri L,Calabrese G,Gervasi T,Dugo G,Cicero N

更新日期：2018-08-01 00:00:00

abstract：:The chemical investigation of the leaves and stem bark of Acacia polyacantha (Fabaceae) led to the isolation of a new oleanane-type triterpenoid saponin named polyacanthoside A 1 together with fifteen known compounds. Their structures were established from spectral , mainly HRESIMS, 1D NMR and 2D NMR and by comparison...

journal_title：Natural product research

authors： Fotso W G,Na-Iya J,Mbaveng T A,Ango Yves P,Demirtas I,Kuete V,Samuel Y,Ngameni B,Efferth T,Ngadjui T B

更新日期：2019-12-01 00:00:00

abstract：:Phebaclavin I, a novel 3-prenylated coumarin, was isolated from the aerial parts of Phebalium aff. tuberculosum (Rutaceae) together with five known related compounds, Phebaclavin A, B, D, G, H. The structure of phebaclavin I was established by spectroscopic methods. Several other known coumarins were obtained, includi...

journal_title：Natural product research

authors： Roux D,Muyard F,Girard C,Colombain M,Tillequin F,Waterman PG,Bévalot F

更新日期：2006-03-01 00:00:00

abstract：:Chemical investigation of the fungus Xylariaceae sp. DPZ-SY43 has led to the isolation of a new compound, xylaolide A (1) together with three known compounds (2-4). The structures were established by analysing the spectroscopic data. Compound 1 was evaluated for its cytotoxicity. ...

journal_title：Natural product research

authors： Yang B,Dong J,Lin X,Tao H,Zhou X,Liu Y

更新日期：2014-01-01 00:00:00