Abstract:
:A new benzophenone glycoside, mitraphenone A (1), together with three known compounds (2-4) were isolated from the leaves of the traditionally used medicinal plant Mitracarpus villosus (Rubiaceae) collected in Nigeria. A combination of one- and two-dimensional NMR spectroscopic and mass spectrometric measurements were carried out to identify the structure of 1. All isolated compounds (1-4) were screened for their antibacterial activity against several Gram-positive and Gram-negative bacteria. Compound 1 exhibited moderate activity against Enterococcus faecium (strains ATCC 35667 and ATCC 700221) and Staphylococcus aureus ATCC 25923 with MIC values ranging from 25 to 50 μM.
journal_name
Nat Prod Resjournal_title
Natural product researchauthors
Ngwoke KG,Orame N,Liu S,Okoye FBC,Daletos G,Proksch Pdoi
10.1080/14786419.2017.1306701subject
Has Abstractpub_date
2017-10-01 00:00:00pages
2354-2360issue
20eissn
1478-6419issn
1478-6427journal_volume
31pub_type
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