Abstract:
:A novel alkaloid named oleraciamide C (1), with six known compounds, hydroxydihydrobovolide (2), uracil (3), catechol (4), 4-aminophenol (5), vanillic acid (6) as well as 3-hydroxypyridine (7), were isolated from Portulaca oleracea L. Additionally, hydroxydihydrobovolide (2), 4-aminophenol (5), 3-hydroxypyridine (7) were obtained from the plant for the first time. Structure of the new compound was determined using spectroscopic methods including HR-ESI-TOF-MS, 1D and 2D NMR. Others were elucidated through 1H NMR, 13C NMR spectra and comparison with literature data. Notably, Compound 1 possessed an unusual bis-substituted eight-membered ring linked with the β-glucopyranose moiety. The cytotoxicity of compound 1 was evaluated against human adipose-derived stem cells (hADSCs) by CCK-8 method.
journal_name
Nat Prod Resjournal_title
Natural product researchauthors
Xu L,Ying Z,Wei W,Hao D,Wang H,Zhang W,Li C,Jiang M,Ying X,Liu Jdoi
10.1080/14786419.2016.1253081subject
Has Abstractpub_date
2017-04-01 00:00:00pages
902-908issue
8eissn
1478-6419issn
1478-6427journal_volume
31pub_type
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