Abstract:
:Phytochemical investigation on the stem bark of Shorea maxwelliana yielded five oligostilbenoids identified as α-viniferin (1), maximol A (2), vaticanol A (3), suffruticosol A (4) and vaticanol G (5). Chemotaxonomy of isolated compounds was discussed briefly. Major compounds were tested for neurotoxic and cytotoxic activities. Neurotoxicity for all tested compounds did not pose any toxic effect against cultured cell (cell viability range ±100-94%). Compounds 2-5 possessed active cyctotoxic activity against HL60 cell line with IC50 values range of 2.7-78 µg mL(-1).
journal_name
Nat Prod Resjournal_title
Natural product researchauthors
Zawawi NK,Ahmat N,Mazatulikhma MZ,Shafiq RM,Wahid NH,Sufian ASdoi
10.1080/14786419.2012.730047subject
Has Abstractpub_date
2013-01-01 00:00:00pages
1589-93issue
17eissn
1478-6419issn
1478-6427journal_volume
27pub_type
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