Bioactive oligostilbenoids from Shorea maxwelliana King and their chemotaxonomic significance.

Abstract:

:Phytochemical investigation on the stem bark of Shorea maxwelliana yielded five oligostilbenoids identified as α-viniferin (1), maximol A (2), vaticanol A (3), suffruticosol A (4) and vaticanol G (5). Chemotaxonomy of isolated compounds was discussed briefly. Major compounds were tested for neurotoxic and cytotoxic activities. Neurotoxicity for all tested compounds did not pose any toxic effect against cultured cell (cell viability range ±100-94%). Compounds 2-5 possessed active cyctotoxic activity against HL60 cell line with IC50 values range of 2.7-78 µg mL(-1).

journal_name

Nat Prod Res

journal_title

Natural product research

authors

Zawawi NK,Ahmat N,Mazatulikhma MZ,Shafiq RM,Wahid NH,Sufian AS

doi

10.1080/14786419.2012.730047

subject

Has Abstract

pub_date

2013-01-01 00:00:00

pages

1589-93

issue

17

eissn

1478-6419

issn

1478-6427

journal_volume

27

pub_type

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