The roots of Salvia rhytidea: a rich source of biologically active diterpenoids.

Abstract:

:Sahandinone (1), 12-deoxysalvipisone (2), miltirone (3), 7α-acetoxyroyleanone (4), and labda-7,14-dien-13-ol (5) were isolated from the roots of Salvia rhytidea Benth. (Lamiaceae). Their structures were elucidated by a combination of spectroscopic analyses including EIMS and NMR. The 13C NMR spectroscopic data were revised for the quaternary carbons of both 1 and 3 with the help of HMBC spectra in respect to the spectral data previously reported in the literature. Compounds 1 and 3, two very potent anticancer agents, were isolated in high yields from the roots of the plant. The biological activities of the plants' constituents were reported in the literature as antimicrobial, cytotoxic and antimalarial are discussed in this article.

journal_name

Nat Prod Res

journal_title

Natural product research

authors

Jassbi AR,Eghtesadi F,Hazeri N,Ma'sumi H,Valizadeh J,Chandran JN,Schneider B,Baldwin IT

doi

10.1080/14786419.2016.1188096

subject

Has Abstract

pub_date

2017-02-01 00:00:00

pages

477-481

issue

4

eissn

1478-6419

issn

1478-6427

journal_volume

31

pub_type

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