Abstract:
:The aims of the present study were to determine the antibacterial activity of bark extract of Cryptomeria japonica D. Don and to isolate potential antibacterial constituents. The results showed that the ethanolic extract of C. japonica bark possessed a good antibacterial activity. Nine compounds including seven diterpenoids (ferruginol (I), isopimaric acid (II), iguestol (III), isopimarol (IV), phyllocladan-16alpha-ol (V), sandaracopimarinol (VI) and sugiol (VII)) and two steroids (beta-sitosterol (VIII) and beta-sitostenone (IX)) were isolated from active subfractions; beta-sitostenone was isolated for the first time from this plant. Among these compounds, ferruginol possessed the strongest antibacterial activity and had MIC values ranging from 6.3 to 12.5 microg mL(-1) against all bacteria tested. Isopimaric acid was also an antibacterial natural product. Cryptomeria japonica bark extract and its diterpenoids, ferruginol and isopimaric acid, have the ability to inhibit the bacterial growth and can be used as the source for natural bactericides.
journal_name
Nat Prod Resjournal_title
Natural product researchauthors
Li WH,Chang ST,Chang SC,Chang HTdoi
10.1080/14786410802267510subject
Has Abstractpub_date
2008-01-01 00:00:00pages
1085-93issue
12eissn
1478-6419issn
1478-6427pii
902333574journal_volume
22pub_type
杂志文章abstract::A new flavanone glycoside, (2S)-dihydrooroxylin A 7-O-[β-D-apiosyl(1 → 2)]-β-D-glucoside (1), and four known compounds (2-5) were isolated from Tournefortia sibirica L. The chemical structures of these compounds were determined by 1 D and 2 D NMR and HR-ESI-MS spectra, and r...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2018.1512995
更新日期:2019-10-01 00:00:00
abstract::The aim of study was to compare the content of phenolic acids and flavonoids in two cultivars of Lavandula angustifolia: 'Blue River' and 'Ellagance Purple', including flowers and leafy stalks. Total phenolics and total flavonoids contents were determined by UV-Vis spectroscopy. The contents of total phenolics in leaf...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2017.1320792
更新日期:2017-11-01 00:00:00
abstract::This paper aims to investigate, for the first time, physicochemical characteristics and antioxidant capacity of Psidium myrtoides ripe and unripe fruit. In addition, essential oil was extracted from fresh leaves (PM-EO) collected in dry and rainy seasons to investigate the influence of seasonality and, after that, to ...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2020.1844689
更新日期:2020-11-09 00:00:00
abstract::Two new and one known compounds were isolated from the methanol extract of Sesamum indicum leaves. By means of spectroscopic methods, their structures were elucidated and identified to be 3-epibartogenic acid (1), kaempferol 3-O-[2-O-(trans-p-coumaroyl)-3-O-α-L-rhamnopyranosyl]-β-D-glucopyranoside (2) and epigallocate...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2015.1057730
更新日期:2016-01-01 00:00:00
abstract::The present study was designed to evaluate the herbicidal activity of Datura metel against the noxious weed parthenium (Parthenium hysterophorus L.). In a laboratory bioassay, the effect of aqueous, methanol and n-hexane shoot and root extracts of 5, 10, 15 and 20% w/v (on a fresh weight basis) concentration of D. met...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786410903075440
更新日期:2010-09-01 00:00:00
abstract::The essential oil of Cyclospermum leptophyllum (Pers.) Sprague ex Britton and P. Wilson syn. Apium leptophyllum (Pers.) F. Muell. Ex Benth., family Apiaceae (Umbellifereae), was analysed by GC and GC-MS. The essential oil showed the presence of thymohydroquinone dimethyl ether (50.7%), thymol methyl ether (11.2%), γ-t...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2010.487190
更新日期:2011-03-01 00:00:00
abstract::Essential oils from aerial parts of Senecio nutans, Senecio viridis, Tagetes terniflora and Aloysia gratissima were analysed by GC-MS and their antifungal activities were assayed on toxigenic Fusarium and Aspergillus species. Sabinene (27.6 ± 0.1%), α-phellandrene (15.7 ± 0.3%), o-cymene (9.6 ± 0.2%) and β-pinene (6.1...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2018.1511555
更新日期:2020-05-01 00:00:00
abstract::Two new compounds, identified as 3-(2-hydroxybenzyl)-6,8-dimethoxy-4H-chromen-4-one (1), named oleracone J and 3-(2-hydroxybenzyl)-6,8-dimethoxychroman-4-one (2), named oleracone K, were isolated from Portulaca oleracea L., and the structures of them were determined by spectroscopy, including one-dimensional and two-d...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2020.1815742
更新日期:2020-09-03 00:00:00
abstract::Three new compounds; epi-mukulin, (Z)-Δ(1,2) dehydroguggulsterone and Δ(6,7)dehydro-20-hydroxygugglsterone were isolated from the n-hexane-soluble fraction (HSF) of the methanol extract of guggul, the oleogum resin of Commiphora wightii together with six known compounds: diasesartemin, (+)-epi-magnolin, (+)-diayangamb...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2012.662651
更新日期:2013-01-01 00:00:00
abstract::Investigation on the leaves of Melicope bonwickii (F.Muell.) T.Hartley (Rutaceae) afforded a new 7-(2'-hydroxy-3'-chloroprenyloxy)-4-methoxyfuroquinoline (1) together with the known 7-(2',3'-epoxyprenyloxy)-4-methoxyfuroquinoline (2), evellerine (3) kokusaginine (4) and an amide aurantiamide acetate (5). Compounds 1 a...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786410500462983
更新日期:2006-04-01 00:00:00
abstract::Six known metabolites, two new isocoumarins 4 and 8, and one new highly substituted benzoic acid derivative 9 were isolated from the ethyl acetate culture extract of a fungal endophyte, Scytalidium sp. In addition, another new benzoic acid 10 with an unusual 1,2-dicarbonyl side chain was indirectly identified from its...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786410310001620637
更新日期:2004-06-01 00:00:00
abstract::4-Methoxybenzene-1-ONN-azoxyformamide (1), 4-methoxybenzene-1-azoformamide (2), 4-hydroxyben-zene-1-azoformamide (3) and 4-hydroxybenzene-1-ONN-azoxyformamide (4) were isolated from the fruiting bodies of Calvatia craniiformis and Lycoperdon hiemale, respectively. Compounds 1 and 4 showed radicle growth inhibitory act...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786410600649596
更新日期:2006-05-10 00:00:00
abstract::The natural product lupeol 1 was isolated from aerial parts of Vernonia scorpioides with satisfactory yield, which made it viable to be used as starting material in semisynthetic approach. Ten lupeol derivatives 2-11 were prepared by classical procedures. Including, five new esters derivatives 7-11, which were obtaine...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2017.1353982
更新日期:2018-02-01 00:00:00
abstract::Stichopus hermanni and Stichopus vastus are sea cucumber species from the Stichopodidae family within the coastal waters of Malaysia. The integument of these invertebrates is hypothesised to contain abundant glycosaminoglycans (GAGs). GAGs are divided into non-sulphated and sulphated GAGs. Sulphated GAGs have various ...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2010.545354
更新日期:2012-01-01 00:00:00
abstract::From the leaves of Mallotus apelta two new benzopyran compounds (1,2) were obtained and their structures were determined using spectroscopic methods. ...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/1057563031000072569
更新日期:2003-10-01 00:00:00
abstract::A new C20-diterpenoid alkaloid carmichaedine (1) and six known alkaloids (2-7) were isolated from the lateral roots of Aconitum carmichaeli. Their structures were established on the basis of extensive spectroscopic analyses. Compound 1 exhibited potent antibacterial activity against Bacillus subtilis with minimum inhi...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2016.1219863
更新日期:2017-01-01 00:00:00
abstract::Plants, in their life cycle, are usually exposed to various kinds of non-biological stresses including heavy metals. One of these heavy metals is nickel which affects many physiological processes of plants. Studies have shown that the changes in planting conditions can affect the qualitative and quantitative features ...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2014.913240
更新日期:2014-01-01 00:00:00
abstract::A new ent-kaurane diterpenoid, lophanthodin G (1) and one known abietanoid, 6alpha-hydroxyferruginol (2), were isolated from the leaves of Isodon lophanthoides var. geradianus. The structure of the new compound 1 was established using spectroscopic methods including extensive 1D and 2D NMR analysis. ...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786410701640619
更新日期:2008-01-01 00:00:00
abstract::Two new compounds including a new 3-arylcoumarin liquiritcoumarin (1), and a new flavonoid glycoside crotoliquiritin (2), together with twelve known compounds (3-14) were isolated from the radix and rhizome of Glycyrrhiza uralensis. Their structures were elucidated on the basis of extensive spectroscopic data analyses...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2020.1715398
更新日期:2020-01-30 00:00:00
abstract::The content of total polyphenols, chlorogenic, caffeic (CaA) and ferulic acids, and rutin, was investigated in plant organs of three introgression lines (IL7-3, IL10-1 and IL12-4) of Solanum pennellii in Solanum lycopersicum cv M82 and compared with that of cropped parental. Such study aims to evidence factors associa...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2012.704371
更新日期:2013-01-01 00:00:00
abstract::The proposed work, aims to provide a "green" and cutting-edge technique for the mordanting and dyeing of polyester fabric with natural henna dye using the advanced technology of micro waves. For providing a complete "green" and ecofriendly dyeing process, lemon was used as a natural bio mordant with micro waves and re...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2019.1619721
更新日期:2021-01-01 00:00:00
abstract::Thirty semicarbazone and thiosemicarbazone derivatives (2a-w and 4a-g) from chalcones containing furan and thiophene ring were designed and synthesized. They were characterized by IR, 1H NMR, 13C NMR and HRMS. The crystal structure of compound 2r was characterized by single crystal X-ray diffraction. It crystallizes i...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2020.1739679
更新日期:2020-03-16 00:00:00
abstract::One known bis-indole alkaloid-voacamine was isolated from Voacanga africana Stapf and Surface Plasmon Resonance imaging (SPRi) exprement showed that this alkaloid could be combine with Protein Tyrosine Phosphatase1B (PTP1B). Then the PTP1B activity inhibition experiment display that the compound showed an outstanding ...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2018.1480623
更新日期:2019-12-01 00:00:00
abstract::Cultivation of the marine-derived Aspergillus versicolor MCCC 3A00080 with the addition of a histone deacetylase inhibitor, suberoylanilide hydroxamic acid (SAHA), significantly enhanced the diversity of secondary metabolites. From the culture treated, a new biphenyl derivative, named versiperol A (1), along with two ...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2018.1465423
更新日期:2019-04-01 00:00:00
abstract::Nine lupeol derivatives were synthesised and assayed in vitro for their antitumour activities against three human tumour cells lines, A549, LAC and HepG2. Of lupeol derivaties, six were new compounds, and five compounds against A549 cells, four compounds against HepG2 cells and three compounds against LAC cells were e...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2017.1329729
更新日期:2018-01-01 00:00:00
abstract::Among phenolic compounds, Agave americana L. extract contained puerarin (38.4%) and p-coumaric acid (12.29%) (pCa). From the Lineweaver-Burk plots, pCa and puerarin demonstrated a competitive and a non competitive inhibitions towards human α-amylase activity, respectively. PCa exhibited a higher human inhibitory activ...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2017.1408094
更新日期:2019-03-01 00:00:00
abstract::Two new anthraquinone malonylglucosides polygonins A and B were isolated from Polygonum cuspidatum along with seven known compounds. The structures of 1 and 2 were elucidated based on their spectroscopic data. ...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2011.578072
更新日期:2012-01-01 00:00:00
abstract::Herein we report the regioselective synthesis of podophyllotoxin-Glycosyl triazole hybrids catalysed by Ag(I)-N-heterocyclic carbene (Ag(I)-NHC) in a short reaction time (∼30 min) at ambient conditions. In principle, it is the first report of Click alkyne-azide cycloaddition catalysed by Ag(I)-NHC catalyst and moreove...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2019.1610958
更新日期:2021-01-01 00:00:00
abstract::Two new ent-atisanes ent-1β,3β,16β,17-tetrahydroxyatisane (1), ent-1β,3α,16β,17-tetrahydroxyatisane (2) together with 11 known diterpenes were isolated from the anti-tumour activity fraction of Euphorbia fischeriana Steud. The compounds were identified by detailed spectroscopic analysis, including extensive 2D-NMR exp...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2015.1045904
更新日期:2016-01-01 00:00:00
abstract::A total of 25 compounds including terpenoids, flavonoids, biflavonoids and ginkgolic acids were identified and quantified with a reliable, simple, and simultaneous method from Ginkgo leaves, seed coats and embryoids with different tree ages (approximately identified as 25, 500, 1000 and 2000 years). Leaves had the hig...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2020.1788020
更新日期:2020-07-01 00:00:00