One bis-indole alkaloid-voacamine from Voacanga africana Stapf: biological activity evaluation of PTP1B in vitro utilizing enzymology method based on SPRi expriment.

Abstract:

:One known bis-indole alkaloid-voacamine was isolated from Voacanga africana Stapf and Surface Plasmon Resonance imaging (SPRi) exprement showed that this alkaloid could be combine with Protein Tyrosine Phosphatase1B (PTP1B). Then the PTP1B activity inhibition experiment display that the compound showed an outstanding promoting activity to PTP1B.

journal_name

Nat Prod Res

journal_title

Natural product research

authors

Wang YQ,Li HX,Liu XC,Zhao JS,Liu RQ,Huai WY,Ding WJ,Zhang TE,Deng Y

doi

10.1080/14786419.2018.1480623

subject

Has Abstract

pub_date

2019-12-01 00:00:00

pages

3459-3463

issue

23

eissn

1478-6419

issn

1478-6427

journal_volume

33

pub_type

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