Abstract:
:Six new compounds, including three terpenoids (1-3) and three lignans (4-6), were isolated from the 95% EtOH extract of the twigs of Tripterygium hypoglaucum. Their structures were determined on the basis of extensive spectroscopic analysis. 9'-O-benzoyl-lariciresinol (4) showed weak cytotoxicity against HepG2/Adr cells, with an IC50 value of 30.1 μM in vitro.
journal_name
Nat Prod Resjournal_title
Natural product researchauthors
Zheng H,Wang L,Yang T,Liu D,Li HM,Chen XQ,Li RTdoi
10.1080/14786419.2018.1564297subject
Has Abstractpub_date
2020-07-01 00:00:00pages
1853-1861issue
13eissn
1478-6419issn
1478-6427journal_volume
34pub_type
杂志文章abstract::N-methylasimilobine (1), a new-found strong acetylcholinesterase (AChE) inhibitor, along with two weakly active aporphine alkaloids, nuciferine (2) and nornuciferine (3) were separated from Nelumbo nucifera. N-methylasimilobine (1) inhibited 50% of AChE activity at the concentrations of 1.5 ± 0.2 µg mL(-1) when the st...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2010.487188
更新日期:2012-01-01 00:00:00
abstract::A new oligostilbenoid, diptoindonesin C, has been isolated from the tree bark of Shorea pinanga Scheff., along with the two known oligostilbenoids gnetin H and hopeaphenol, and a known coumarin scopoletin. The new oligostilbenoid was moderately active against brine shrimps Artemia salina. ...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786410600761235
更新日期:2009-01-01 00:00:00
abstract::Synsepalum dulcifificum is an evergreen shrub native of tropical West Africa. It is very effective against a variety of diseases. However, the phytochemical investigation on this plant is limited till now. In our current study, seventeen compounds were isolated and identified from the ethyl acetate extract of the leav...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2020.1830394
更新日期:2020-10-09 00:00:00
abstract::The search for bioactive natural products from the rhizomes of Paris polyphylla (Trilliaceae) has resulted in the isolation of four known constituents, 1,5-dihydroxy-7-methoxy-3-methylanthraquinone (1), diosgenin-3-O-[alpha-L-rhamnopyranosyl-(1 --> 3)-beta-D-glucopyranoside] (2), diosgenin-3-O-[alpha-L-rhamnopyranosyl...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786410701192777
更新日期:2007-04-01 00:00:00
abstract::A new pentacyclic triterpenoid fatty acid ester, lupan-20-ol-3(β)-yl hexadecanoate (1), together with lupan-20-ol-3(β)-yl acetate (2), olean-18-en-3(β)-yl hexadecanoate (3), dotriacontanoic acid (4), stigmasterol (5), rubiadin (6), nonadecanoic acid (7), palmitic acid (8) and camptothecin (9) were isolated from the he...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2016.1160232
更新日期:2016-10-01 00:00:00
abstract::Three new aconitine-type C19-diterpenoid alkaloids, taipeinines A-C (1-3), were isolated from the roots of Aconitum taipaicum. The chemical structures of these three compounds were established as (1α,6α,8α,14α,16α)-20-ethyl-8,14-dihydroxy-1,6,16-trimethoxy-4-(methoxymethyl)-aconitane (1), (1α,6α,8α,14α,16β)-20-ethyl-8...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2013.861832
更新日期:2014-01-01 00:00:00
abstract::Phytochemical investigation of methanolic extract of Adenium obesum led to the isolation of 42 (1-42) compounds belongs to cardiac glycosides, triterpenoids and steroids. The chemical structures of isolated compounds were elucidated by spectral techniques UV, IR, NMR and FAB MS. The cardiac glycosides were tested agai...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2016.1226826
更新日期:2017-05-01 00:00:00
abstract::Evaluation of in vitro standard antioxidant assays, such as 1,1-diphenyl-2-picrylhydrazyl (DPPH), 2,2'-azino-bis-3 ethylbenzothiozoline-6-sulphonic acid diammonium salt (ABTS+) radical scavenging, lipid peroxidation inhibitory (or thiobarbituric acid formation inhibitory activity) and ferrous ion (Fe+2) chelating acti...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2017.1375923
更新日期:2018-11-01 00:00:00
abstract::Two new compounds, myrubol (1) and 3-oxo-11α-hydroxyfriedelane (2), were isolated from the roots of Myrica rubra along with eight known compounds (3-10). Their structures were determined through (1)H-NMR and (13)C-NMR spectral data, including 2-D experiments (HMBC, HMQC, (1)H-(1)H COSY and NOESY) and high-resolution m...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2010.516749
更新日期:2011-01-01 00:00:00
abstract::Neuroprotection under conditions of oxygen stress of two C21 steroidal glycosides, cynsaccatol Q (1) and saccatol K (2), isolated from Cynanchum auriculatum Royle ex Wight, and their potential mechanisms were studied using the model of H2O2-induced damage on PC12 cells in this paper. Experiments showed that compounds ...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2019.1636241
更新日期:2019-07-02 00:00:00
abstract::A new and efficient synthesis of a naturally occurring amide alkaloid, N-isobutyl-4,5-epoxy-2(E)-decenamide isolated from the roots of Piper nigrum has been described involving a total of nine steps. Octanal and 2-bromoacetic acid have been used as the starting materials. ...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2012.678349
更新日期:2013-01-01 00:00:00
abstract::The objective of this work was to produce and characterise nanoemulsions containing tucumã extract and to evaluate the performance of the nanostructure and the free compound regarding antitumor activity, cytotoxicity, and oxidative metabolism in NB4/APL cells. The nanoemulsions showed adequate physicochemical characte...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2020.1862830
更新日期:2020-12-24 00:00:00
abstract::A new diterpenoid glycoside, 14,15-dinor-labdan-13-one-8-O-alpha-L-arabinopyranoside (1), was isolated from Conyza blinii. The structure of this new arabinoside was elucidated on the basis of extensive NMR and HRMS spectroscopy. In addition, the presence of 3R-hydroxyoctadecanoic acid in C. blinii was reported for the...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786410701592232
更新日期:2008-04-15 00:00:00
abstract::A new 24-membered macrolide, 5'-epi-SPA-6952A (1), was isolated from the cultured broth of Streptomyces diastatochromogenes. The structure was elucidated by means of spectroscopic methods and comparing with literature data of the known 24-membered macrolide SPA-6952A. Compound 1 was found to show significant insectici...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2017.1405401
更新日期:2019-03-01 00:00:00
abstract::This work was carried out to study the effect of topical application of Andrographis paniculata on the rate of wound enclosure and its histological features. A wound was created in four groups of rat in posterior neck region. Blank placebo was applied topically to the wounds of Group 1. Groups 2 and 3 were dressed wit...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2010.496114
更新日期:2012-01-01 00:00:00
abstract::The methanolic extract of the aerial parts of Datura innoxia afforded a new withanolide, daturacin, the structure of which was elucidated as (20R, 22S)-21,24-epoxy-1,6-dioxo-14alpha-methoxy-5beta-witha-2,25(27)-dienolide (1) by an analysis of the spectroscopic data, including extensive NMR experiments. ...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786410512331330620
更新日期:2005-09-01 00:00:00
abstract::Fructose feeding induces a rise in blood pressure in normal rats that is associated with insulin resistance, hyperinsulinemia, hyperglycaemia, hypercholesterolaemia and hypertriglyceridaemia. We have examined the effect of chronic administration of A-HRS (100 and 300 mg kg⁻¹; p.o.) isolated from Hibiscus rosa sinensis...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2010.534473
更新日期:2012-01-01 00:00:00
abstract::A total of 205 bluefin and yellowfin tuna samples were examined for mercury detection in order to verify possible differences and have a detailed risk assessment of the two tuna species. The results showed significant higher mercury concentration in muscle tissue of bluefin tuna respect yellowfin tuna (p < 0.001) with...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2017.1309538
更新日期:2018-02-01 00:00:00
abstract::A new highly oxygenated germacranolide, carcerlane A (1), together with four known highly oxygenated germacranolides (2-5), was isolated from an ethanol extract of the whole plant of Carpesium nepalense var. lanatum (C.B.Clarke) Kitam. The structures were determined by HRESIMS and extensive analysis of their spectrosc...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2020.1833199
更新日期:2020-10-22 00:00:00
abstract::A new dolabellane diterpenoid (1R*,3E,7E,9S*,11S*,12Z)-9-hydroxydolabella-3,7,12-triene (1), along with seven known compounds (2-8), has been isolated from the Hainan soft coral Spongodes sp. Their structures were elucidated on the basis of spectroscopic analysis and compared with those previously reported in literatu...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786410601130034
更新日期:2007-08-01 00:00:00
abstract::Phytochemical investigation of the extracts of the leaves of Siparuna thecaphora (Poepp. et Endl.) A. DC. (Siparunaceae) allowed the isolation of one monoterpene glycoside, named trans-thujane-1α,7-diol 1-O-β-D-glucopyranoside (1) along with rutin, quercetin 3-O-β-D-glucopyranoside and 3,4-dihydroxybenzaldehyde. Their...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2013.843179
更新日期:2014-01-01 00:00:00
abstract::Cedronella canariensis is a lemon-scented species of the family Lamiaceae endemic to the Canary Islands where it is used in the traditional medicine to prepare infusions or inhalations for anti-catarrhal, tonic, diuretic, hypoglycaemiant, hypotensive, anti-inflammatory and decongestant of the respiratory tract. In thi...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2014.994213
更新日期:2015-01-01 00:00:00
abstract::Essential oils from the leaves, twigs and barks of Bocageopsis pleiosperma Maas were obtained by using hydrodistillation and analysed by using gas chromatography coupled to mass spectrometry. Several compounds (51) were detected and identified, being β-bisabolene the main component in all aerial parts of the plant, wi...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2014.996148
更新日期:2015-01-01 00:00:00
abstract::Chemical investigation of the stems of Epigunum griffithianum led to the isolation and identification of a new triterpenoid saponin (1) and two known compounds (epigynosides A (2) and B (3)). These structures were elucidated by means of spectroscopic analysis (1D and 2D NMR, MS, UV, IR) as well as comparison with the ...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2018.1512989
更新日期:2020-05-01 00:00:00
abstract::This study reports for the first time in the chemical composition of acetone, ether, ethyl acetate and dichloromethane extracts of Hypogymnia tubulosa determined by HPLC-UV, GC-FID and GC-MS as well as effect of H. tubulosa acetone extract on micronucleus distribution on human lymphocytes and on cholinesterase activit...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2017.1375926
更新日期:2018-11-01 00:00:00
abstract::As part of our continuing efforts to explore bioactive compounds from natural resources, a new iridoid glycoside, adoxosidic acid-6'-oleuroperic ester (1), together with one known phenylethanoid glycoside (2) and two known flavonoid glycosides (3-4) were isolated from the fruit of Forsythia suspensa. The structure of ...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2018.1560288
更新日期:2020-05-01 00:00:00
abstract::This paper aims to investigate, for the first time, physicochemical characteristics and antioxidant capacity of Psidium myrtoides ripe and unripe fruit. In addition, essential oil was extracted from fresh leaves (PM-EO) collected in dry and rainy seasons to investigate the influence of seasonality and, after that, to ...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2020.1844689
更新日期:2020-11-09 00:00:00
abstract::Two new C13-norsesquiterpenes claulanterpene A (1) and B (2), together with two known sesquiterpenes (3-4), were isolated from methanol extract of the stem and leaf of Clausena lansium collected from Qingyuan county, Guangdong Province, China. Their structures were elucidated on the base of extensive spectroscopic ana...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2020.1741577
更新日期:2020-03-25 00:00:00
abstract::One new triterpenoid olean-18-ene-1β, 2α, 3β-triol (1) along with four known compounds were isolated from the chloroform extract of the aerial part of Salvia atropatana Bunge. The known compounds were two flavonoids, 5-hydroxy-7,4'-dimethoxyflavone (2) and 5-hydroxy-6,7,4'-trimethoxyflavone (3), an abietane-type diter...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2011.628668
更新日期:2012-01-01 00:00:00
abstract::As part of our search for compounds with cytotoxicity from endophytes of traditional Chinese medicines, two novel nor-sesquiterpenoids (1-2) with a new skeleton containing a tetrahydrofuran moiety were isolated form a rice medium of Fusarium tricinctum, an endophytic fungus isolated from the root of Ligusticum chuanxi...
journal_title:Natural product research
pub_type: 杂志文章
doi:10.1080/14786419.2020.1712385
更新日期:2020-01-24 00:00:00