A new highly oxygenated germacranolide from Carpesium nepalense var. lanatum (C.B.Clarke) Kitam.

abstract：:(+)-7-O-Methylisomiroestrol (MeI), a novel chromene, was discovered as a phytoestrogen in the Pueraria candollei var. mirifica (Airy Shaw & Suvat.) Niyomdham (PM) root having been used as an active agent against oestrogen depletion disorders. The identification of PM phytochemicals is crucial for the development of st...

journal_title：Natural product research

authors： Yusakul G,Juengsanguanpornsuk W,Sritularak B,Phaisan S,Juengwatanatrakul T,Putalun W

更新日期：2020-02-20 00:00:00

abstract：:A novel macrolide with dioxa and double ring pentadecanone, named as phoxalone, isolated from the culture broth of a myxobacterium Sorangium cellulosum WXNXJ-C, was well investigated. The chemical structure of Phoxalone was elucidated by spectroscopic analysis including UV, IR, (1)H NMR, MALDI-TOF-MS, and LC/MS spectr...

journal_title：Natural product research

authors： Guo WJ,Tao WY,Bi F

更新日期：2007-12-01 00:00:00

abstract：:A series of novel hydrocarbylidene nitrohydrazinecarboximidamides were designed and synthesized using an insecticidal natural product Galegine as a lead compound. The bioassay results show that the target compounds exhibited moderate to good insecticidal activities against Hyalopterus pruni Geoffroy at a concentration...

journal_title：Natural product research

authors： Wu Q,Zhao F,Zhu X,Zhou Z,Yang D,Xu Z,Li J,Qin Z

更新日期：2019-08-20 00:00:00

abstract：:To obtain more accessible oxidative stress inhibitors, a series of novel spin-labelled derivatives of 3-hydroxybutanolide (2a-d, 3a-d) with the natural active compound (kinsenoside) as the lead compound were designed, synthesised from the nitroxide free radical piperidine (pyrroline) and the main structural unit of ki...

journal_title：Natural product research

authors： Liu Q,Liu ZL,Tian J,Shi W,Liu YQ

更新日期：2014-01-01 00:00:00

abstract：:A new isoflavone, 4'-prenyloxyvigvexin A (1) and a new pterocarpan, (6aR,11aR)-3,8-dimethoxybitucarpin B (2) were isolated from the leaves of Lonchocarpus bussei and the stem bark of Lonchocarpus eriocalyx, respectively. The extract of L. bussei also gave four known isoflavones, maximaisoflavone H, 7,2'-dimethoxy-3',4...

journal_title：Natural product research

authors： Adem FA,Kuete V,Mbaveng AT,Heydenreich M,Koch A,Ndakala A,Irungu B,Yenesew A,Efferth T

更新日期：2019-09-01 00:00:00

abstract：:Two new sesquiterpenoid glycosides as dihydrophaseic acid 4'-O-[6″-O-(4″'-hydroxy-3″', 5″'-dimethoxy) benzoyl)]-β-D-glucopyranoside (1) and dihydrophaseic acid 4'-O-[6″-O-(3″'-methoxy- 4″'-hydroxy) benzoyl)]-β-D-glucopyranoside (2), were isolated from the stems of Zanthoxylum armatum in the study. The compound 1 and 2...

journal_title：Natural product research

authors： Liu YL,Gao LL,Song TT,Guo T,Chang J

更新日期：2020-11-01 00:00:00

abstract：:The aim of study was to compare the content of phenolic acids and flavonoids in two cultivars of Lavandula angustifolia: 'Blue River' and 'Ellagance Purple', including flowers and leafy stalks. Total phenolics and total flavonoids contents were determined by UV-Vis spectroscopy. The contents of total phenolics in leaf...

journal_title：Natural product research

authors： Adaszyńska-Skwirzyńska M,Dzięcioł M

更新日期：2017-11-01 00:00:00

abstract：:Phytochemical investigation on the stem bark of Shorea maxwelliana yielded five oligostilbenoids identified as α-viniferin (1), maximol A (2), vaticanol A (3), suffruticosol A (4) and vaticanol G (5). Chemotaxonomy of isolated compounds was discussed briefly. Major compounds were tested for neurotoxic and cytotoxic ac...

journal_title：Natural product research

authors： Zawawi NK,Ahmat N,Mazatulikhma MZ,Shafiq RM,Wahid NH,Sufian AS

更新日期：2013-01-01 00:00:00

abstract：:The chemical constituents identified in the essential oils hydrodistilled from the leaves of Amomum gagnepainii T.L.Wu, K.Larsen and Turland and Amomum repoense Pierre ex Gagnep (Zingiberaceae) of Vietnam origin are reported. The chemical analyses were performed by means of gas chromatography-flame ionisation detector...

journal_title：Natural product research

authors： Huong LT,Hung NV,Chung MV,Dai DN,Ogunwande IA

更新日期：2018-02-01 00:00:00

abstract：:The ethanol extract of roots of Solidago canadensis yielded eight labdane-type diterpenes. Five of those were new natural compounds (9,13,15,16-bisepoxy-labdane-7-ene-6,15-dione (3a), 13-epi-9,13,15,16-bisepoxy-labdane-7-ene-6,15-dione (3b), 15,16-epoxy-labdane-7,13-diene-6,16-dione (5), 15-ethoxy-9,13,15,16-bisepoxy-...

journal_title：Natural product research

authors： Wangensteen H,Phan TT,Rise F,Halvorsen TG,Malterud KE

更新日期：2012-01-01 00:00:00

abstract：:A new oligostilbenoid, diptoindonesin C, has been isolated from the tree bark of Shorea pinanga Scheff., along with the two known oligostilbenoids gnetin H and hopeaphenol, and a known coumarin scopoletin. The new oligostilbenoid was moderately active against brine shrimps Artemia salina. ...

journal_title：Natural product research

authors： Syah YM,Hakim EH,Ghisalberti EL,Jayuska A,Mujahidin D,Achmad SA

更新日期：2009-01-01 00:00:00

abstract：:The chemical investigation of whole plants Piper terminaliflorum Tseng led to the isolation of one new furofuran lignan, 7-methoxyasarinin (1), along with three known amide alkaloids (2-4) as N-3,5-dimethoxy-4-hydroxycinnamoylpyrrole (2), dihydropipercide (3) and 1-[(2E,4E,9E)-10-(3,4-Methylenedioxyphenyl)-2,4,9-undec...

journal_title：Natural product research

authors： Liu T,Liang Q,Zhang XM,Huang SY,Xu WH

更新日期：2018-02-01 00:00:00

abstract：:Eight steroids, including five withanolides (1-5) and three other ergostane-type steroids (6-8), were isolated from the aerial parts of the halophyte Datura stramonium L., which were collected from the Yellow River Delta in China. Their structures were elucidated on the basis of extensive spectroscopic methods, especi...

journal_title：Natural product research

authors： Fang ST,Liu X,Kong NN,Liu SJ,Xia CH

更新日期：2013-01-01 00:00:00

abstract：:Chemical investigation of the mycelial extract of a mixed culture of two marine alga-derived fungal strains of the genus Aspergillus has yielded one new cyclotripeptide, psychrophilin E (1), the recently reported oxepin-containing alkaloids, protuboxepin A (2) and oxepinamide E (3), together with three other polyketid...

journal_title：Natural product research

authors： Ebada SS,Fischer T,Hamacher A,Du FY,Roth YO,Kassack MU,Wang BG,Roth EH

更新日期：2014-01-01 00:00:00

abstract：:From the fruiting body of ectomycorrhizal fungi Cortinarius xiphidipus, sterols were identified from the crude extract and the cytotoxic effect of ergosta-4, 6, 8(14), 22-tetraen-3-one (ergone) was evaluated. Ten sterols including ergosta-3,5,7,9(11),22-pentaene, (22E)-ergosta-5,7,9(11),22-tetraen-3b-ol, (3β,22E)-ergo...

journal_title：Natural product research

authors： Torres S,Cajas D,Palfner G,Astuya A,Aballay A,Pérez C,Hernández V,Becerra J

更新日期：2017-02-01 00:00:00

abstract：:A novel isoindole alkaloid named oleraisoindole (1), together with six known compounds, 7'-ethoxy-trans-feruloyltyramine (2), N-trans-feruloyltyramine (3), N-trans-feruloyl-3-methoxytyramine (4), N-trans-p-coumaroyltyramine (5) aurantiamide (6) and ferulic acid methyl ester (7) were isolated from Portulaca oleracea L....

journal_title：Natural product research

authors： Jiang M,Zhang W,Yang X,Xiu F,Xu H,Ying X,Stien D

更新日期：2018-10-01 00:00:00

abstract：:This article investigates the effect of microwaves on the amount of volatile compounds Achillea tenuifolia Lam with two methods, headspace single-drop microextraction and microwave-assisted headspace single-drop microextraction (MA-SDME), for the analysis of essential oil. Solvent selection, solvent volume, microwave ...

journal_title：Natural product research

authors： Piryaei M,Nazemiyeh H

更新日期：2016-01-01 00:00:00

abstract：:Diphysidione (1), a new p-hydroxyphenyl anhydride, and vitexin (2) were isolated from the leaves of Diphysa carthagenensis. The structure of the new metabolite was characterised as 4-(4-hydroxy-phenyl)-3H-pyran-2,6-dione using 1D and 2D NMR spectroscopy. ...

journal_title：Natural product research

authors： Torres-Tapia LW,Sosa-Espinosa T,Peraza-Sánchez SR

更新日期：2013-01-01 00:00:00

abstract：:Phytochemical investigation of Eucommia ulmoides Oliver staminate flowers provided twenty-seven compounds, including 11 triterpenes (1-11), 4 fatty acids (12-15), 1 coumarin (16), 1 chromone (17), 7 flavonoids (18-24) and 3 cyclopeptide alkaloids (25-27). Compounds 4-6, 8-9, 11-15, 17 and 25-27 were reported for the f...

journal_title：Natural product research

authors： Li R,Nie L,Wang Q,Ouyang D,Zhang L,Yuan Y,Hong Y,Wang J,Hu X

更新日期：2020-12-12 00:00:00

abstract：:Chemical investigation of the stems of Epigunum griffithianum led to the isolation and identification of a new triterpenoid saponin (1) and two known compounds (epigynosides A (2) and B (3)). These structures were elucidated by means of spectroscopic analysis (1D and 2D NMR, MS, UV, IR) as well as comparison with the ...

journal_title：Natural product research

authors： Wang Q,Li WY,Wang YD

更新日期：2020-05-01 00:00:00

abstract：:Four C-13, C-14 side chain modified 9(R)-hydroxy-1-deoxy-taxane analogues 15, 16, 19 and 22 were semi-synthesized from 1-deoxybaccatin VI. The in vitro antitumor activity of these compounds was evaluated against A549 and A2780 cell lines. The preliminary SAR analysis showed that introduction of oxygen-containing group...

journal_title：Natural product research

authors： Tang P,Lin HX,Yuan TH,Cui YM

更新日期：2019-12-01 00:00:00

abstract：:New ent-trachylobane-3β-hydroperoxide (5) together with four known compounds, ricinine (1), trimethoxy ellagic acid (2), dimethoxy ellagic acid (3) and aleurotolic acid (4) were isolated from the methylene chloride fraction of the root bark of Chrozophora oblongifolia. The structures of these secondary metabolites wer...

journal_title：Natural product research

authors： Kamel MR,Nafady AM,Hassanein AMM,Hassan AR,Shimizu K,Ibrahim RR,Haggag EG

更新日期：2019-11-06 00:00:00

abstract：:This study evaluates the presence, location and production source of tetrodotoxin (TTX) in two species of pufferfish, Diodon histrix and Arothron hispidus, common to Hawaiian waters. Organs from each fish were analysed for TTX and used to isolate bacteria for evaluation of possible TTX production. Comparative analyses...

journal_title：Natural product research

authors： Campbell S,Harada RM,DeFelice SV,Bienfang PK,Li QX

更新日期：2009-01-01 00:00:00

abstract：:The use of natural products as a diet supplement is increasing worldwide but sometimes is not followed by adequate sanitary controls and analyses. Twenty samples of pills and capsules of lyophilised cyanobacteria (blue-green algae), commercialised in Italy as dietary supplements, were found positive at the Vibrio fisc...

journal_title：Natural product research

authors： Bruno M,Fiori M,Mattei D,Melchiorre S,Messineo V,Volpi F,Bogialli S,Nazzari M

更新日期：2006-07-20 00:00:00

abstract：:Inula graveolens (L.) Desf. is an annual aromatic herb which has various uses on alternative medicine in many region of the world. In this study, antioxidant activities of ethanol and water extracts of the plant leaves were determined by in vitro DPPH method and phenolic composition of the plant sample was determined ...

journal_title：Natural product research

authors： Silinsin M,Bursal E

更新日期：2018-06-01 00:00:00

abstract：:Platelet aggregation is fundamental to a wide range of physiological and pathological processes, including the induction of thrombosis and arteriosclerosis. Anti-platelet activity of a crude methanol extract and solvent fractions of Ashitaba roots (Angelica keiskei Koidz.) was evaluated using a turbidimetric method us...

journal_title：Natural product research

authors： Son DJ,Park YO,Yu C,Lee SE,Park YH

更新日期：2014-01-01 00:00:00

abstract：:The lipid peroxidation inhibitory activities of four hydroxyxanthones, isolated from the whole plant Swertia decussata, were evaluated for the first time. The most promising antioxidant among the xanthones, 1,7,8-trihydroxy-3-methoxyxanthone (swertianine, 4) was also tested for its scavenging potential against DPPH an...

journal_title：Natural product research

authors： Patro BS,Chintalwar GJ,Chattopadhyay S

更新日期：2005-06-01 00:00:00

abstract：:This study describes the in vitro inhibition of protein denaturation of extract/fractions of Withania somnifera and isolated withanolides including 20β hydroxy-1-oxo(22R)-witha-2,5,24 trienolide (1), (20R,22R-14α,20α)-dihydroxy-1-oxowitha-2,5,16,24 tetraenolide (2). The results showed that the extract/fractions of the...

journal_title：Natural product research

authors： Khan MA,Khan H,Rauf A,Ben Hadda T

更新日期：2015-01-01 00:00:00

abstract：:Biotransformation of corosolic acid (1) by Cochliobolus lunatus and Streptomyces asparaginoviolaceus afforded four metabolites, which were identified by using (1)H NMR, (13)C NMR, DEPT, HSQC, HMBC and NOESY spectral data. Biotransformation of corosolic acid by C. lunatus R.R. Nelson & Haasis CGMCC 3.4381 produced thre...

journal_title：Natural product research

authors： Feng X,Li DP,Zhang ZS,Chu ZY,Luan J

更新日期：2014-01-01 00:00:00

abstract：:Bioassay guided chemical investigation of the gorgonian Pacifigorgia senta led to the discovery of a new 19-oxygenated steroid, cholesta-5,24-diene-3β,7β,19-triol (1), as well as three known steroids (2-4). The structure of 1 was determined by extensive spectroscopic analysis, including NMR and MS spectra. All of the ...

journal_title：Natural product research

authors： Chen M,Han L,Zhang XL,Wang CY

更新日期：2016-06-01 00:00:00