ELISA and LC-MS/MS methods for determining cyanobacterial toxins in blue-green algae food supplements.

abstract：:The chemical composition of the volatile concentrate prepared by supercritical CO(2) extraction of the needles of Pinus nigra Arnold ssp. laricio Poiret from Corsica was investigated using GC (RI), GC-MS and (13)C NMR spectroscopy. The major component was by far manoyl oxide (63%), a compound of potential interest for...

journal_title：Natural product research

authors： Duquesnoy E,Marongiu B,Castola V,Piras A,Porcedda S,Casanova J

更新日期：2007-07-20 00:00:00

abstract：:Triterpene saponins are throught to be potential anti-tumour agents in many cell types. This study aims to evaluate the cytotoxic activity and mechanism of a triterpene saponin, macranthoside B (MB), isolated from Lonicera macranthoides Hand.-Mazz. (Caprifoliaceae). A cell viability assay showed that MB inhibited cell...

journal_title：Natural product research

authors： Guan F,Shan Y,Zhao X,Zhang D,Wang M,Peng F,Xia B,Feng X

更新日期：2011-02-01 00:00:00

abstract：:Mangrove plants are endowed with various biologically active compounds which have potent antibacterial and antioxidant properties. In present study, a bioactivity-guided fractionation for antibacterial and antioxidant active metabolites from the twigs of Avicennia officinalis collected from Kuala Selangor Nature Park,...

journal_title：Natural product research

authors： Assaw S,Mohd Amir MIH,Khaw TT,Bakar K,Mohd Radzi SA,Mazlan NW

更新日期：2020-08-01 00:00:00

abstract：:A new oleanolic-type triterpene glycoside, (3β,21β)-21-[(β-d-glucopyranosyl-(1→2)-β-d-glucopyranosyl)oxy]-3-hydroxyolean-12-en-28-oic acid (1), together with five analogues, oleanazuroside 1 (2), oleanazuroside 2 (3), 24-hydroxytormentic acid ester glucoside (4), 24-epi-pinfaensin (5), and oleanolic acid 3-O-α-l-arabi...

journal_title：Natural product research

authors： Chen KK,Xie ZJ,Dai W,Wang Q

更新日期：2017-04-01 00:00:00

abstract：:In this study, Moringa oleifera flower extract and a trypsin inhibitor (MoFTI) isolated from it were evaluated for anti-protozoal activity against Trypanosoma cruzi and cytotoxicity to mammalian cells. The presence of flavonoids was remarkable in the HPLC fingerprints of the extract at 254 and 360 nm. Amino acid seque...

journal_title：Natural product research

authors： Pontual EV,Pires-Neto DF,Fraige K,Higino TMM,Carvalho BEA,Alves NMP,Lima TA,Zingali RB,Coelho LCBB,Bolzani VS,Figueiredo RCBQ,Napoleão TH,Paiva PMG

更新日期：2018-12-01 00:00:00

abstract：:The present study has been focused on the extraction of natural pigments from tomato industry waste. At first, different solvents and solvents mixture were compared to determine which one is the best for extracting carotenoids compounds from tomato by-products. A mixture of hexane and acetone gave the highest caroteno...

journal_title：Natural product research

authors： Baaka N,El Ksibi I,Mhenni MF

更新日期：2017-01-01 00:00:00

abstract：:Bothrops jararacussu venom's (Bj2015) batch was biomonitored quarterly for one year to assess phospholipase A2 (PLA2) activity, immunogenicity, neurotoxicity, and myotoxicity. In silico models were applied to evaluate losses using decay model and recoveries by predictive trend analysis. Mice were immunized with Bj2015...

journal_title：Natural product research

authors： Oliveira ICF,Mora AD,Neto JB,de Oliveira ÁL,Harder C,Hanai-Yoshida VM,Cogo JC,Floriano RS,Bonventi Junior W,Oliveira SJ,Oshima-Franco Y

更新日期：2019-08-01 00:00:00

abstract：:Microwave assisted Diels-Alder cycloaddition of 5-Br-N-benzylpyridinone (2) with methyl acrylate is described to gain an easy access to 7-bromo-2-benzyl-3-oxo-2-aza-5 or 6-carbomethoxy bicyclo[2.2.2]oct-7-enes (3)-(6). The preparation of the ibogaine analogue 20-desethyl-(20-endo)-hydroxymethyl-11-demethoxyibogaine (1...

journal_title：Natural product research

authors： Passarella D,Barilli A,Efange SM,Elisabetsky E,Leal MB,Lesma G,Linck VM,Mash DC,Martinelli M,Peretto I,Silvani A,Danieli B

更新日期：2006-07-10 00:00:00

abstract：:Plumieride (PLU), an iridoid isolated from Allamanda cathartica flowers, has been studied by our research group due to its anti-inflammatory potential, antidepressant-like and anxiolytic-like effects. This research investigated the involvement of GABAergic and monoaminergic systems in the anxiolytic-like effect elicit...

journal_title：Natural product research

authors： Dalmagro AP,Camargo A,Zimath PL,Bonomini TJ,Zeni ALB,Malheiros A,de Souza MM

更新日期：2020-03-11 00:00:00

abstract：:A new C20-diterpenoid alkaloid carmichaedine (1) and six known alkaloids (2-7) were isolated from the lateral roots of Aconitum carmichaeli. Their structures were established on the basis of extensive spectroscopic analyses. Compound 1 exhibited potent antibacterial activity against Bacillus subtilis with minimum inhi...

journal_title：Natural product research

authors： Yu J,Yin TP,Wang JP,Mei RF,Cai L,Ding ZT

更新日期：2017-01-01 00:00:00

abstract：:To date, despite extensive investigations, full understanding of the endocannabinoid system remains elusive; in particular, anandamide cellular uptake is a current controversial topic. An iodo-arylazido probe was synthesized from commercially available azelaic acid monomethyl ester, in order to shed light on the anand...

journal_title：Natural product research

authors： Balas L,Hellal M,Rossi JC,Durand T

更新日期：2005-06-01 00:00:00

abstract：:The current study introduces a new idea of utilising several bio/chemoinformatics tools in comparing two bio-similar natural molecules viz. curcumin and bisdemethoxycurcumin (BDMC) in order to select a potential nose-to-brain remedy for Alzheimer disease. The comparison comprised several bio/chemo informatics tools. I...

journal_title：Natural product research

authors： Hathout RM,El-Ahmady SH,Metwally AA

更新日期：2018-12-01 00:00:00

abstract：:Headspace solid-phase microextraction (HS-SPME) coupled with gas chromatography (GC-FID) was explored to determine the fingerprinting characteristic of Zingiber zerumbet L. volatiles to differentiate between different ginger species. The effect of different fibers [polydimethylsiloxane (PDMS, 7 μm), polyacrylate (PA, ...

journal_title：Natural product research

authors： Bhavya ML,Ravi R,Madhava Naidu M

更新日期：2019-07-22 00:00:00

abstract：:New analogues of a long-chain secondary alcohol (1) and laserine (2) were isolated from the flowers of Tamarix hampeana L. The isolated compounds were identified using 1D and 2D NMR, LCMS/APCI, and chemical methods. Laserine was isolated for the first time from T. hampeana L. ...

journal_title：Natural product research

authors： Aykac A,Akgül Y

更新日期：2010-01-01 00:00:00

abstract：:A new denudatine-type C20-diterpenoid alkaloid, pubesine (1), along with seven known diterpenoid alkaloids, altaconitine (2), 14-benzoylaconine (3), spicatine A (4), 14-benzoylaconine-8-palmitate (5), 14-O-acetylsenbusine A (6), senbusine A (7) and 14-acetylneoline (8) were isolated from the whole plant of Aconitum so...

journal_title：Natural product research

authors： Chen L,Shan L,Xu W,Zhang J,Huang S,Zhou X

更新日期：2017-03-01 00:00:00

abstract：:This work reports on the composition and bionutritional value of organic virgin olive oil from the Nocellara del Belice variety, one cultivated in the olive areas of the Sicily region, Italy. Destoned oils obtained by processing olives with a destoning-based procedure were compared with conventional oils. This innovat...

journal_title：Natural product research

authors： Ranalli F,Ranalli A,Contento S,Casanovas M,Antonucci M,Simone GD

更新日期：2013-01-01 00:00:00

abstract：:The actinomycete strain FIM06-0036 was isolated from marine sponge sample collected from the East China Sea and identified as Verrucosispora sp. based upon the results of 16S rRNA sequence analysis. One new alkaloid, 2-ethylhexyl 1H-imidazole-4-carboxylate (1), together with a known alkaloid butyl 1H-imidazole-4-carbo...

journal_title：Natural product research

authors： Chen MH,Lian YY,Fang DS,Chen L,Jia J,Zhang WL,Lin R,Xie Y,Bi HK,Jiang H

更新日期：2019-11-15 00:00:00

abstract：:Phytochemical investigation of methanolic extract of Adenium obesum led to the isolation of 42 (1-42) compounds belongs to cardiac glycosides, triterpenoids and steroids. The chemical structures of isolated compounds were elucidated by spectral techniques UV, IR, NMR and FAB MS. The cardiac glycosides were tested agai...

journal_title：Natural product research

authors： Ahmed SK,Versiani MA,Ikram A,Sattar SA,Faizi S

更新日期：2017-05-01 00:00:00

abstract：:To obtain more accessible oxidative stress inhibitors, a series of novel spin-labelled derivatives of 3-hydroxybutanolide (2a-d, 3a-d) with the natural active compound (kinsenoside) as the lead compound were designed, synthesised from the nitroxide free radical piperidine (pyrroline) and the main structural unit of ki...

journal_title：Natural product research

authors： Liu Q,Liu ZL,Tian J,Shi W,Liu YQ

更新日期：2014-01-01 00:00:00

abstract：:Chemical investigation of the Red Sea sponge Dragmacidon coccinea led to the isolation of a new nucleoside, dragmacidoside (1), along with eight known compounds: adenosine (2), inosine (3), deoxycytidine (4), methyl-α-d-glucopyranoside (5), clionasterol (6), stigmasterol (7), campesterol (8) and brassicasterol (9). Th...

journal_title：Natural product research

authors： Abou-Hussein DR,Badr JM,Youssef DT

更新日期：2014-01-01 00:00:00

abstract：:The antimicrobial activities of plant extracts have formed the basis of many alternative medicines. In this context, the genus Schinus L. (Anacardiaceae), exhibits many traditional uses in medicine. However, a few studies on the antimicrobial properties of Schinus areira essential oils were conducted. The essential oi...

journal_title：Natural product research

authors： Cutro AC,Castelli MV,López SN,Rosales MA,Hollmann A,Rodriguez SA

更新日期：2019-10-12 00:00:00

abstract：:The aim of this work was to provide a characterisation of volatile constituents from different commercial batches of henna (Lawsonia inermis) leaves of different geographic origin. Headspace solid-phase microextraction (HS-SPME) coupled with gas chromatography-mass spectrometry (GC-MS) was used for the purpose. A tota...

journal_title：Natural product research

authors： Mengoni T,Peregrina DV,Censi R,Cortese M,Ricciutelli M,Maggi F,Di Martino P

更新日期：2016-01-01 00:00:00

abstract：:Antioxidant, anticholinesterase and antidiabetic activities of three curcuminoids isolated from the Curcuma longa were simultaneously tested and compared in this study. The highest antioxidant power was detected for curcumin with the applied methods. The drug potentials of curcuminoids for Alzheimer's disease were con...

journal_title：Natural product research

authors： Kalaycıoğlu Z,Gazioğlu I,Erim FB

更新日期：2017-12-01 00:00:00

abstract：:A new protein detector of 2,4,6-trinitrophenol (TNP, picric acid) is concisely reported herein for the first time. In brief, the gene of a specific scFv fragment, namely 3.5, was fused separately with the gene of β-lactamase and, subsequently, expressed in the periplasmic space of Escherichia coli, affording in such a...

journal_title：Natural product research

authors： Simonovic M,Mix T,Glumac M,Pejin B

更新日期：2020-12-18 00:00:00

abstract：:These are the days when one would go online first seeking home remedies before seeing a doctor. Apple cider vinegar (ACV) is one such popular yet scientifically under-validated remedy. Our results prove the unequivocal antimicrobial activity of ACV to be true at full strength concentrations. However, the activity cann...

journal_title：Natural product research

authors： Gopal J,Anthonydhason V,Muthu M,Gansukh E,Jung S,Chul S,Iyyakkannu S

更新日期：2019-03-01 00:00:00

abstract：:The anticancer activity of ethanol extract isolated from Goji berry (EEGB) on T47D human breast cancer cell line has been reported. Cell viability and cell proliferation were examined with the use of BrdU, MTT and NR methods. Induction of apoptosis was assessed by propidium iodide and Hoechst 33342 staining. Expressio...

journal_title：Natural product research

authors： Wawruszak A,Czerwonka A,Okła K,Rzeski W

更新日期：2016-09-01 00:00:00

abstract：:A new highly oxygenated germacranolide, carcerlane A (1), together with four known highly oxygenated germacranolides (2-5), was isolated from an ethanol extract of the whole plant of Carpesium nepalense var. lanatum (C.B.Clarke) Kitam. The structures were determined by HRESIMS and extensive analysis of their spectrosc...

journal_title：Natural product research

authors： Yu YF,Li YQ,Wang RY,Liu X,Cui WB,Chen XH,Zhao CM,Qi FM,Zhang ZX,Fei DQ

更新日期：2020-10-22 00:00:00

abstract：:From the seed and leaf extracts of Eryngium species, two new compounds were isolated, along with an aliphatic ketone and several known terpenoids reported from a member of Umbelliferae for the first time. Their structures were elucidated by chemical methods and spectroscopic analysis. ...

journal_title：Natural product research

authors： Muckensturm B,Boulanger A,Farahi M,Reduron JP

更新日期：2010-03-01 00:00:00

abstract：:Monoterpene glycosides have been isolated from the ethyl acetate soluble fraction of Indigofera hetrantha and their structures assigned to be 3,7-dimethyl-2(E),6-octadien-5-one-1-O-beta-D-6-O-acetylglucopyranoside (1) and 3,7-dimethyl-2(E), 6-octadien-5-one-1-O-[-beta-D-6''-O-acetylglucopyra-nosyl (1'' --> 6')-beta-D-...

journal_title：Natural product research

authors： Mehmood S,Aziz-Ur-Rahman,Ahmad Z,Afza N,Malik A,Ahmad H,Choudhary MI

更新日期：2008-01-01 00:00:00

abstract：:The ethanolic extract of the bulbs of Fritillaria imperialis was subjected to fractionation by solvent-solvent extraction. The nonpolar fraction showed inhibitory activity against prolyl endopeptidase (PEP) (EC.3.4.21.26), a large intracellular enzyme that preferentially hydrolyze proline-containing oligopeptidase at ...

journal_title：Natural product research

authors： Atta-ur-Rahman,Akhtar MN,Choudhary MI,Tsuda Y,Yasin A,Sener B,Parvez M

更新日期：2005-01-01 00:00:00