Cytotoxic cardiac glycosides from the fruit (pods) of Adenium obesum (Forssk.) Roem. & Schult.

abstract：:Cochliomycin G (1), a new 14-membered resorcylic acid lactone, together with six known analogues (2-7), was isolated from the culture broth of a marine-derived fungus Cochliobolus lunatus. The planar structure of 1 was established by extensive NMR spectroscopy, and the absolute configuration was elucidated by the comb...

journal_title：Natural product research

authors： Xu WF,Xue XJ,Qi YX,Wu NN,Wang CY,Shao CL

更新日期：2021-02-01 00:00:00

abstract：:In this study, phytochemical composition, antioxidant, enzyme inhibition and cytotoxic activities of methanol and dichloromethane (DCM) extracts of Bougainvillea glabra (B. glabra) flowers were investigated. Methanol extract was found to have higher total bioactive contents and UHPLC-MS analysis of methanol extract re...

journal_title：Natural product research

authors： Saleem H,Htar TT,Naidu R,Zengin G,Ahmad I,Ahemad N

更新日期：2020-09-01 00:00:00

abstract：:From the fruit of Pandanus tectorius Parkinson ex Du Roi, one new (1) and six known aldehyde compounds (2-7) were isolated by various chromatography methods. Based on their spectroscopic data, these compounds were identified as (Z)-4-hydroxy-3-(4-hydroxy-3-methylbut-2-en-1-yl) benzaldehyde (1), p-hydroxybenzaldehyde (...

journal_title：Natural product research

authors： Mai DT,Le TD,Nguyen TP,Phan NM,Nguyen HA,Nguyen TT,Tran le Q

更新日期：2015-01-01 00:00:00

abstract：:Epicatechin (EC) is the most effective compound in Euonymus alatus (Thunb.)Sieb, and possesses a series of benefits, including anti-inflammatory, antioxidant, antiobesity and anticancer effects. In this study, we investigated the protective effects of EC in Acetaminophen(N-acetyl-p-aminophenol, APAP)-induced acute liv...

journal_title：Natural product research

authors： Wu H,Xie Y,Xu Y,Hu Z,Wan X,Huang H,Huang D

更新日期：2020-03-01 00:00:00

abstract：:This study aimed at evaluating the impact of environmental factors on the accumulation of various components in Hedera helix L. folium collected from different European countries. The obtained results of studied samples showed that the antioxidant capacities were in the range of 0.027 to 0.688 mg/g. Contents of active...

journal_title：Natural product research

authors： Bezruk I,Materiienko A,Gubar S,Proskurina K,Budanova L,Ivanauskas L,Georgiyants V

更新日期：2020-11-04 00:00:00

abstract：:Mahuang Fuzi Xixin (MFX), a classic recipe in traditional Chinese medicine, belongs to an exterior-relieving formula. For quality control of the MFX products, qualitative analysis using ultra-high performance liquid chromatography with diode-array detector-tandem mass spectrometry (UPLC-PDA-MS/MS) was undertaken. Six ...

journal_title：Natural product research

authors： Zhang L,Wang C,Miao D,Yuan D,Bi K,Yang J,Zhan L

更新日期：2015-01-01 00:00:00

abstract：:Investigations were performed on the determination of the main components in Berchemia lineata (L.) DC. (BL) and its metabolism with human liver microsomes (HLM). A total of 35 compounds were detected in BL extracts and 25 of them including 6 naphthopyrones, 10 flavonoids, 2 phenolic acids, 2 phenols, 4 fatty acids an...

journal_title：Natural product research

authors： Jiang X,Chen S,Guo Z,Gu D,Liang X

更新日期：2021-02-01 00:00:00

abstract：:This study is part of a wider investigation aimed to sustain the economical value of the by-products generated by the Citrus industry. In particular, the protected geographic indication (PGI) red orange of sicily (known as blood orange) has been analysed by HPLC and by the enzymatic AOAC method. All the by-products co...

journal_title：Natural product research

authors： Russo M,Bonaccorsi IL,Arigò A,Cacciola F,De Gara L,Dugo P,Mondello L

更新日期：2019-11-29 00:00:00

abstract：:Five phenanthrene and two dihydrophenanthrene derivatives were isolated from the diethyl ether extract of fresh rhizomes of Dioscorea communis (L.), among them a phenanthrentriol 1 reported for the first time from Dioscoreaceae family and two dihydrophenanthrene derivatives 6 and 7 reported also for the first time fro...

journal_title：Natural product research

authors： Boudjada A,Touil A,Bensouici C,Bendif H,Rhouati S

更新日期：2019-11-01 00:00:00

abstract：:Two saponins: scrokoelziside A (1), scrokoelziside B (2), one iridoid glycoside, eurostoside (3), and two flavonoids: nepitrin (4) and homoplantaginin (5), were isolated from the leaves of Scrophularia ningpoensis for the first time. Moreover, eight known compounds: cane sugar (6), harpagide (7), aucubin (8), 6-O-meth...

journal_title：Natural product research

authors： Li J,Huang X,Du X,Sun W,Zhang Y

更新日期：2009-01-01 00:00:00

abstract：:A new C20-diterpenoid alkaloid carmichaedine (1) and six known alkaloids (2-7) were isolated from the lateral roots of Aconitum carmichaeli. Their structures were established on the basis of extensive spectroscopic analyses. Compound 1 exhibited potent antibacterial activity against Bacillus subtilis with minimum inhi...

journal_title：Natural product research

authors： Yu J,Yin TP,Wang JP,Mei RF,Cai L,Ding ZT

更新日期：2017-01-01 00:00:00

abstract：:The objective of this study was to determine whether endophytic fungi, isolated from Kadsura angustifolia produce nigranoic acid and its highly oxygenated derivatives. From the 426 endophytic fungi screened, Trichoderma harzianum SWUKD3.1610 was detected to have a component with the same TLC R ...

journal_title：Natural product research

authors： Han M,Qin D,Ye T,Yan X,Wang J,Duan X,Dong J

更新日期：2019-07-01 00:00:00

abstract：:Edible flowers consumption has increased in recent years due to their rich content of healthy phytochemicals. The aim of this study was to analyse the chemical profile of Cucurbita pepo L. flowers, and to explore their antioxidant and hypoglycaemic properties. Moreover, in order to assess in vivo effects, biochemical ...

journal_title：Natural product research

authors： Morittu VM,Musco N,Mastellone V,Bonesi M,Britti D,Infascelli F,Loizzo MR,Tundis R,Sicari V,Tudisco R,Lombardi P

更新日期：2019-09-30 00:00:00

abstract：:This work reports the results and the comparison concerning the chemical and biomolecular analyses and the antifungal activity of three wild Pistacia species (Anacardiaceae) from Sardinia. Volatile oils from leaves and twigs of Pistacia x saportae, Pistacia lentiscus and Pistacia terebinthus were characterised using G...

journal_title：Natural product research

authors： Marengo A,Piras A,Falconieri D,Porcedda S,Caboni P,Cortis P,Foddis C,Loi C,Gonçalves MJ,Salgueiro L,Maxia A

更新日期：2018-12-01 00:00:00

abstract：:The crystal structure and unambiguous absolute configuration of meleagrin (1) isolated from fungus Emericella dentata Nq45 is reported herein to first time on the bases of single crystal X-ray diffraction. Together with 1, haenamindole (2), isorugulosuvine (3), secalonic acid D (4), ergosterol (5) and cerebroside A (6...

journal_title：Natural product research

authors： Hamed A,Abdel-Razek AS,Araby M,Abu-Elghait M,El-Hosari DG,Frese M,Soliman HSM,Stammler HG,Sewald N,Shaaban M

更新日期：2020-03-19 00:00:00

abstract：:A new furan derivative named 3-(5-oxo-2,5-dihydrofuran-3-yl) propanoic acid (1) was isolated for the first time. Its structure was elucidated by UV, IR, NMR, HR-ESI-MS and the single-crystal X-ray diffraction spectroscopic data. Meanwhile, the antifungal and antibacterial activities of compound 1 was tested, it exhibi...

journal_title：Natural product research

authors： Yang XF,Wang NN,Kang YF,Ma YM

更新日期：2019-10-01 00:00:00

abstract：:Two new cycloartane-type glycosides, caspicuside I and caspicuside II, were isolated along with two known saponins, cycloastragenol and astragaloside IV, from the roots of Astragalus caspicus. As the aglycon group, caspicuside I possesses 3beta,6alpha,16beta,(24S),25-pentahydroxycycloartane (cyclocanthagenol), while c...

journal_title：Natural product research

authors： Fathiazad F,Khosropanah MK,Movafeghi A

更新日期：2010-07-01 00:00:00

abstract：:The Perovskia artemisioides Boiss. essential oil obtained by hydrodistillation method of flowers growing wild in the north of Iran. The study led to the identification of 29 compositions by a combination of HP-5 GC-FID and GC-MS analytical techniques. The constituents were identified in P. artemisioides essential oil ...

journal_title：Natural product research

authors： Hafez Ghoran S,Azadi B,Hussain H

更新日期：2016-09-01 00:00:00

abstract：:An aroma chemical emitted from Gerris paludum insularis was analyzed by means of GC and GC-MS. The main constituent was identified as iso amyl alcohol (3-methyl-1-butanol). The chemical showed a characteristic aroma of Gerris paludum insularis. ...

journal_title：Natural product research

authors： Ono T,Miyazawa M

更新日期：2004-06-01 00:00:00

abstract：:Two new compounds including a new 3-arylcoumarin liquiritcoumarin (1), and a new flavonoid glycoside crotoliquiritin (2), together with twelve known compounds (3-14) were isolated from the radix and rhizome of Glycyrrhiza uralensis. Their structures were elucidated on the basis of extensive spectroscopic data analyses...

journal_title：Natural product research

authors： Wang M,Yang W,Liu X,Liu Q,Zheng H,Wang X,Shen T,Wang S,Ren D

更新日期：2020-01-30 00:00:00

abstract：:Due to the increasing emergence of resistance of bacterial pathogens to current antibiotics, we have examined the marine fungi present in sea sediments obtained 200 m offshore to discover new antibacterial compounds active against multidrug-resistant bacteria. One strain, identified as Emericellopsis minima, was isola...

journal_title：Natural product research

authors： Inostroza A,Lara L,Paz C,Perez A,Galleguillos F,Hernandez V,Becerra J,González-Rocha G,Silva M

更新日期：2018-06-01 00:00:00

abstract：:This study evaluates the presence, location and production source of tetrodotoxin (TTX) in two species of pufferfish, Diodon histrix and Arothron hispidus, common to Hawaiian waters. Organs from each fish were analysed for TTX and used to isolate bacteria for evaluation of possible TTX production. Comparative analyses...

journal_title：Natural product research

authors： Campbell S,Harada RM,DeFelice SV,Bienfang PK,Li QX

更新日期：2009-01-01 00:00:00

abstract：:Oil content in sweet and bitter fennels was obtained 12.22% and 14.41%, respectively. The C(18:1 c6), C(18:2), C(18:1 c9) and C(16:0) acids corresponding to approximately 97% of total oil was recorded as principal fatty acids. The ratios of essential oil from sweet and bitter fennels were found similar (average 3.00%)...

journal_title：Natural product research

authors： Coşge B,Kiralan M,Gürbüz B

更新日期：2008-01-01 00:00:00

abstract：:Five new α-pyrones, xylariaopyrones E-I (1-5), along with three known analogues (6-8) were isolated from the cultivation broth of the endophytic fungus Xylariales sp. (HM-1). The structures of the new compounds including their absolute configurations were elucidated by comprehensive spectroscopic methods and quantum E...

journal_title：Natural product research

authors： Yang WW,Lu LW,Zhang XQ,Bao SS,Cao F,Guo ZY,Deng ZS,Proksch P

更新日期：2020-09-30 00:00:00

abstract：:An activity-guided isolation and purification process was used to identify the l,l-diphenyl-2-picrylhydrazyl (DPPH) free radical-scavenging components of the food plant (Terminalia arjuna) of Antheraea mylitta. Dry leaves of T. arjuna were extracted with different solvents and tested for their antioxidant activity aga...

journal_title：Natural product research

authors： Singh PP,Chauhan SM

更新日期：2014-01-01 00:00:00

abstract：:Known diketopiperazine WIN 64821 and its asymmetric stereoisomers (1-3) had been isolated from the culture broth of a marine gut fungus Aspergillus sp. DX4H. The planar and stereochemistry for new compounds were determined by a suite of techniques including mass, NMR and CD spectra together with Marfey's method. Their...

journal_title：Natural product research

authors： Xu J,Hu Q,Ding W,Wang P,Di Y

更新日期：2018-04-01 00:00:00

abstract：:Two new flavanone glycosides have been isolated from the water soluble part of Veratrum nigrum L., belonging to the family Lilica. The structures of 3',4'-dimethoxyl-quercitrin and 4'-methoxyl-glucotricin have been established with the aid of extensive NMR spectroscopic studies. ...

journal_title：Natural product research

authors： Li HL,Tang J,Liu RH,Zhang C,Zhang WD

更新日期：2009-01-01 00:00:00

abstract：:The methanolic extract of the aerial parts of Datura innoxia afforded a new withanolide, daturacin, the structure of which was elucidated as (20R, 22S)-21,24-epoxy-1,6-dioxo-14alpha-methoxy-5beta-witha-2,25(27)-dienolide (1) by an analysis of the spectroscopic data, including extensive NMR experiments. ...

journal_title：Natural product research

authors： Siddiqui BS,Arfeen S,Begum S,Sattar FA

更新日期：2005-09-01 00:00:00

abstract：:Three Ballota species, Ballota undulata, Ballota saxatilis and Ballota nigra ssp. foetida, were investigated for their cytotoxicity against two human cancer cells, hepatoma HepG2 cell line and breast cancer MCF-7 cell line, and for their antioxidant activity. The chemical composition of essential oils was studied by G...

journal_title：Natural product research

authors： Rigano D,Marrelli M,Formisano C,Menichini F,Senatore F,Bruno M,Conforti F

更新日期：2017-02-01 00:00:00

abstract：:A new thiodiketopiperzaine, tedanizaine A (1), together with six known ones, were isolated from the marine sponge Tedania sp. Their structures were determined by spectroscopic analyses. The absolute configuration of 1 was established by ECD calculation. Compound 1 was the second example of thiodiketopiperazine bearing...

journal_title：Natural product research

authors： Zhang H,Lai W,Guan ZB,Liao XJ,Zhao BX,Xu SH

更新日期：2020-04-01 00:00:00