New asymmetrical bispyrrolidinoindoline diketopiperazines from the marine fungus Aspergillus sp. DX4H.

Abstract:

:Known diketopiperazine WIN 64821 and its asymmetric stereoisomers (1-3) had been isolated from the culture broth of a marine gut fungus Aspergillus sp. DX4H. The planar and stereochemistry for new compounds were determined by a suite of techniques including mass, NMR and CD spectra together with Marfey's method. Their inhibitory activity against PC3 cell line had been tested.

journal_name

Nat Prod Res

journal_title

Natural product research

authors

Xu J,Hu Q,Ding W,Wang P,Di Y

doi

10.1080/14786419.2017.1363752

subject

Has Abstract

pub_date

2018-04-01 00:00:00

pages

815-820

issue

7

eissn

1478-6419

issn

1478-6427

journal_volume

32

pub_type

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