A new anti-proliferative acylated flavonol glycoside from Fuzhuan brick-tea.

abstract：:This work is an attempt to explore the anti-spermatogenic activity of Pistia stratiotes and to investigate it as a male contraceptive. The prepared extracts were screened for the presence of alkaloids, glycosides, steroids, flavonoids, saponin and phenolic compounds. To assess the anti-spermatogenic activity, mice wer...

journal_title：Natural product research

authors： Singh K,Dubey BK,Tripathi AC,Singh AP,Saraf SK

更新日期：2014-01-01 00:00:00

abstract：:Benign prostatic hypertrophy (BPH) is a common condition in elderly men that impairs quality of life and leads to a number of medical complications. The use of phytotherapeutic compounds in patients with relatively moderate BPH symptoms has been growing steadily. In the present study, acute toxicity of lyophilised aqu...

journal_title：Natural product research

authors： Vitali F,Pennisi G,Attaguile G,Savoca F,Tita B

更新日期：2011-02-01 00:00:00

abstract：:An alternative method for the synthesis of the 8-methyl-1-tetralone from the commercially available 5-methoxy-1-tetralone has been developed. The transformation involves eight steps and affords an overall yield 25%. ...

journal_title：Natural product research

authors： Poon PS,Bedoya L,Churio GJ,Banerjee AK

更新日期：2014-01-01 00:00:00

abstract：:An unexpected synthesis of symmetrical hydroxybiphenylmethanes involving the reaction of 2-hydroxyphenyl benzyl ketones with ethoxymethyl chloride has been observed. Some new interesting observations of Labat test on colorimetric detection of bichalconyloxy, bichalconyl and biflavonylmethanes having oxygenated ortho p...

journal_title：Natural product research

authors： Kukreja G,Campiani G,Khurana JM,Joshi BP,Grover SK

更新日期：2006-10-01 00:00:00

abstract：:A new polycyclic polyprenylated acylphloroglucinol (1), nujiangefolin D, together with five known analogues (2-6), were isolated from the fruits of Garcinia nujiangensis. Compound 1 was screened by the LC-MS and LC-PDA. The structure of 1 was elucidated on the basis of extensive spectroscopic techniques including 1 D ...

journal_title：Natural product research

authors： Tang Z,Lu L,Zhou X,Shen J,Song W,Tang Y,Xia Z

更新日期：2020-09-01 00:00:00

abstract：:In this study, phytochemical composition, antioxidant, enzyme inhibition and cytotoxic activities of methanol and dichloromethane (DCM) extracts of Bougainvillea glabra (B. glabra) flowers were investigated. Methanol extract was found to have higher total bioactive contents and UHPLC-MS analysis of methanol extract re...

journal_title：Natural product research

authors： Saleem H,Htar TT,Naidu R,Zengin G,Ahmad I,Ahemad N

更新日期：2020-09-01 00:00:00

abstract：:Phytochemical study on the 95% ethyl alcohol extract of stems of Chenopodium ambrosioides resulted in the isolation of two new polyol monoterpenes, 4-hydroxy-4(α or β)-isopropyl-2-methyl-2-cyclohexen-1-one (1) and 1-methyl-4β- isopropyl-1-cyclohexene-4α,5α,6α-triol (2), together with five known compounds, (1S,2S,3R,4S...

journal_title：Natural product research

authors： Hou SQ,Li YH,Huang XZ,Li R,Lu H,Tian K,Ruan RS,Li YK

更新日期：2017-11-01 00:00:00

abstract：:Phytochemical reinvestigation on the whole plants of Derris laxiflora Benth. afforded two new diprenylated flavanones, derriflavanones B and C (1-2), together with thirty-two known compounds, including sixteen flavonoids (3-18), eleven aromatic compounds (19-29), and five chlorophylls (30-34). All known compounds were...

journal_title：Natural product research

authors： Huang HC,Chien SC,Kuo CC,Wu MD,Cheng MJ,Chen JJ,Chiu HL,Kuo YH

更新日期：2020-08-01 00:00:00

abstract：:The ethanol extract of roots of Solidago canadensis yielded eight labdane-type diterpenes. Five of those were new natural compounds (9,13,15,16-bisepoxy-labdane-7-ene-6,15-dione (3a), 13-epi-9,13,15,16-bisepoxy-labdane-7-ene-6,15-dione (3b), 15,16-epoxy-labdane-7,13-diene-6,16-dione (5), 15-ethoxy-9,13,15,16-bisepoxy-...

journal_title：Natural product research

authors： Wangensteen H,Phan TT,Rise F,Halvorsen TG,Malterud KE

更新日期：2012-01-01 00:00:00

abstract：:In the present investigation, the anti-inflammatory activity of a polyphenolic enriched extract of Schima wallichii bark was evaluated in vitro using human peripheral blood mononuclear cells (PBMCs) and in vivo by carrageenan-induced paw oedema assay (acute study) and cotton pallet granuloma assay (chronic study). The...

journal_title：Natural product research

authors： Dewanjee S,Mandal V,Sahu R,Dua TK,Manna A,Mandal SC

更新日期：2011-04-01 00:00:00

abstract：:Machaerium, in the family Fabaceae, predominantly is a genus of a Neotropical distribution of trees, shrubs, and lianas occurring from southern Mexico to Brazil and northern Argentina and as far as South America. Several Machaerium species are widely used in traditional medicine and are considered to have multiple med...

journal_title：Natural product research

authors： Amen YM,Marzouk AM,Zaghloul MG,Afifi MS

更新日期：2015-01-01 00:00:00

abstract：:To date, despite extensive investigations, full understanding of the endocannabinoid system remains elusive; in particular, anandamide cellular uptake is a current controversial topic. An iodo-arylazido probe was synthesized from commercially available azelaic acid monomethyl ester, in order to shed light on the anand...

journal_title：Natural product research

authors： Balas L,Hellal M,Rossi JC,Durand T

更新日期：2005-06-01 00:00:00

abstract：:Chemical investigation of the aerial parts of Uvaria rufa (Dunal) Blume collected from Vietnam yielded one new lignan glycoside, ufaside (1), along with six known compounds, oxoanolobine (2), ergosta-4,6,8(14),22-tetraen-3-one (3), catechin (4), epicatechin (5), daucosterol (6) and glutin-5-en-3-one (7). Their chemica...

journal_title：Natural product research

authors： Nguyen TH,Ho VD,Do TT,Bui HT,Phan VK,Sak K,Raal A

更新日期：2015-02-01 00:00:00

abstract：:Phytochemical investigation of methanolic extract of Adenium obesum led to the isolation of 42 (1-42) compounds belongs to cardiac glycosides, triterpenoids and steroids. The chemical structures of isolated compounds were elucidated by spectral techniques UV, IR, NMR and FAB MS. The cardiac glycosides were tested agai...

journal_title：Natural product research

authors： Ahmed SK,Versiani MA,Ikram A,Sattar SA,Faizi S

更新日期：2017-05-01 00:00:00

abstract：:A new denudatine-type C20-diterpenoid alkaloid, pubesine (1), along with seven known diterpenoid alkaloids, altaconitine (2), 14-benzoylaconine (3), spicatine A (4), 14-benzoylaconine-8-palmitate (5), 14-O-acetylsenbusine A (6), senbusine A (7) and 14-acetylneoline (8) were isolated from the whole plant of Aconitum so...

journal_title：Natural product research

authors： Chen L,Shan L,Xu W,Zhang J,Huang S,Zhou X

更新日期：2017-03-01 00:00:00

abstract：:A phytochemical reinvestigation of the whole plant of Euphorbia segetalis yielded five tetracyclic triterpenes: 3beta-hydroxy-cycloart-25-en-24-one (1), cycloart-25-ene-3beta,24-diol (2), cycloart-23-ene-3beta,25-diol (3), lanosta-7,9(11),24-trien-3beta-ol (4) and lanosta-7,9(11),24(31)-trien-3beta-ol (5). beta-acetox...

journal_title：Natural product research

authors： Madureira AM,Ascenso JR,Valdeira L,Duarte A,Frade JP,Freitas G,Ferreira MJ

更新日期：2003-10-01 00:00:00

abstract：:The present study was aimed to isolate active constituents from Blumea axillaris (Lam.) DC (Asteraceae) against phytopathogenic fungi. Bioactivity guided fractionation of the successive n-hexane, chloroform and methanol extract led to the isolation of the monoterpene ester (4 R,5S)-4-hydroxy-7-tigloyloxycarvotanaceton...

journal_title：Natural product research

authors： Sivanandhan S,Pathalam G,Antony S,Michael GP,Balakrishna K,Boovaragamurthy A,Shirota O,Alwahibi MS,El-Shikh MS,Ignacimuthu S

更新日期：2020-10-16 00:00:00

abstract：:One new havanensin-type limonoid (1) named trisinlin A with two known compounds (4E,8E)-2-[2'-hydroxyhexadecanoyl amino]-4,8-octadecadiene-1,3-diol (2), 9-octadecenoic acid-2',3'-dihydroxypropyl ester (3) were isolated from the roots of Trichilia sinensis. The structure of the new compound was unambiguously determined...

journal_title：Natural product research

authors： Liu SB,Chen HQ,Feng G,Guo ZK,Cai CH,Wang J,Mei WL,Dai HF

更新日期：2018-12-01 00:00:00

abstract：:The chemical investigation of whole plants Euphorbia stracheyi Boiss from China led to the isolation of one new ent-kaurane diterpene, ent-Kaurane-16β,17,19-triol-3-one (1), along with three known ent-kaurane diterpenoids (2-4) as ent-Kaurane-3α,16β,17-triol (2)，ent-16S,17-dihydroxy-kaurane-3-one (3) and ent-3S,16S,17...

journal_title：Natural product research

authors： Liu T,Liang Q,Xiong NN,Dai LF,Wang JM,Ji XH,Xu WH

更新日期：2017-01-01 00:00:00

abstract：:The optimisation of nutritional requirements for dopamine (DA) synthesis by calcium alginate-entrapped mutant variant of Aspergillus oryzae EMS-6 using submerged fermentation technique was investigated. A total of 13 strains were isolated from soil. Isolate I-2 was selected as a better producer of DA and improved by e...

journal_title：Natural product research

authors： Ali S,Nawaz W

更新日期：2017-02-01 00:00:00

abstract：:One known bis-indole alkaloid-voacamine was isolated from Voacanga africana Stapf and Surface Plasmon Resonance imaging (SPRi) exprement showed that this alkaloid could be combine with Protein Tyrosine Phosphatase1B (PTP1B). Then the PTP1B activity inhibition experiment display that the compound showed an outstanding ...

journal_title：Natural product research

authors： Wang YQ,Li HX,Liu XC,Zhao JS,Liu RQ,Huai WY,Ding WJ,Zhang TE,Deng Y

更新日期：2019-12-01 00:00:00

abstract：:The aerial parts of L. cultratus were submitted to a phytopharmacological investigation in order to isolate and identify the major secondary metabolites and evaluate its crude extract, fractions and isolated compounds for antiproliferative activity. Seven compounds were isolated and identified as the chalcones 2',4'-d...

journal_title：Natural product research

authors： da Silva Landim EMBM,Ruiz ALTG,de Carvalho JE,Pomini AM,Pastorini LH,Oliveira Santin SM

更新日期：2019-08-12 00:00:00

abstract：:Inula graveolens (L.) Desf. is an annual aromatic herb which has various uses on alternative medicine in many region of the world. In this study, antioxidant activities of ethanol and water extracts of the plant leaves were determined by in vitro DPPH method and phenolic composition of the plant sample was determined ...

journal_title：Natural product research

authors： Silinsin M,Bursal E

更新日期：2018-06-01 00:00:00

abstract：:The microbial transformation of androst-4-ene-3,17-dione (4-AD; I) by three fungal species, involved Fusarium solani BH1031, Aspergillus awamori MH18 and Mucor circinelloides W12, has been studied. The latter two fungi were studied for the first time on biotransformation of 4-AD. The main product obtained by Fusarium ...

journal_title：Natural product research

authors： An X,Gao P,Zhao S,Zhu L,You X,Li C,Zhang Q,Shan L

更新日期：2021-02-01 00:00:00

abstract：:Two new polyketides, purpurofuranone (1) and purpuropyranone (2), were isolated along with the known polyketides, cillifuranone (3) and taiwapyrone (4), from a mutant BD-3n-1 derived from the diethyl sulfate (DES) mutagenesis of a marine-derived Penicillium purpurogenum G59. The structures of 1 and 2 were elucidated b...

journal_title：Natural product research

authors： Wu CJ,Qiao H,Cui CB,Yang Y,Xu R,Sun CX,Li DH,Li CW

更新日期：2019-10-01 00:00:00

abstract：:One new sesqui-neolignan compound, namely, sesqui-illisimonan A (1), one new neolignan, illisimonan A (2), and one new phenylpropanoid compound, illisimoid A (3) were isolated from the fruits of Illicium simonsii Maxim. The structures and absolute configurations of these compounds were determined by extensive spectros...

journal_title：Natural product research

authors： Zhuang PY,Chen MH,Wang YN,Wang XX,Feng YJ,Zhang DY

更新日期：2018-10-01 00:00:00

abstract：:Terminalia bellerica has been used as a traditional medicine in a variety of ailments including anaemia, asthma, cancer, inflammation, rheumatism and hypertension. In this study, the free radical scavenging and antioxidant activities of methanol extract (ME) and its different solvent fractions (namely hexane (HE), eth...

journal_title：Natural product research

authors： Nampoothiri SV,Binil Raj SS,Prathapan A,Abhilash PA,Arumughan C,Sundaresan A

更新日期：2011-02-01 00:00:00

abstract：:Two new C-15 enolic acyl phragmalin-type limonoid orthoesters, chukvelutilide G (1) and chukrasine F (2), were isolated from the stem barks of Chukrasia tabularis var. velutina. Their structures were elucidated by their extensive high resolution-electrospray ionization mass spectrometry (HR-ESI-MS), one- and two-dimen...

journal_title：Natural product research

authors： Luo J,Li Y,Wang JS,Kong LY

更新日期：2013-04-01 00:00:00

abstract：:A new highly oxygenated pseudoguaianolide, rudbeckolide (1), was isolated from Rudbeckia hirta L. flowers. The structure of this terpenoid lactone was established on the basis of extensive 1D and 2D NMR spectroscopic analyses. The compound exhibited strong 5-lipoxygenase inhibitory activity (84.9% inhibition at 10 μg/...

journal_title：Natural product research

authors： Michael BR,Gedara SR,Amer MM,Stevenson L,Ahmed AF

更新日期：2013-01-01 00:00:00

abstract：:The subject of this present work is a group of nine historical pictures shot in Palermo by the Sicilian photographer E. Interguglielmi in 1912. They are nine matte-collodion prints mounted on the original cardboard supports and all of them show foxing stains affecting the paper surface. In order to characterise the ch...

journal_title：Natural product research

authors： Modica A,Bruno M,Di Bella M,Alberghina MF,Brai M,Fontana D,Tranchina L

更新日期：2019-04-01 00:00:00