Abstract:
:A new highly oxygenated pseudoguaianolide, rudbeckolide (1), was isolated from Rudbeckia hirta L. flowers. The structure of this terpenoid lactone was established on the basis of extensive 1D and 2D NMR spectroscopic analyses. The compound exhibited strong 5-lipoxygenase inhibitory activity (84.9% inhibition at 10 μg/mL) in vitro and the result provided partial evidence for the usage of the plant as traditional medicine.
journal_name
Nat Prod Resjournal_title
Natural product researchauthors
Michael BR,Gedara SR,Amer MM,Stevenson L,Ahmed AFdoi
10.1080/14786419.2013.825916subject
Has Abstractpub_date
2013-01-01 00:00:00pages
2281-5issue
24eissn
1478-6419issn
1478-6427journal_volume
27pub_type
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