Abstract:
:A series of 4-hydroxy-3,4-dialkyl-2,6-diaryl-piperidine (7-12) have been synthesised by reduction of 3-alkyl-2,6-diarylpiperidin-4-one using the Grignard reagent. Structural assignments and conformational analysis of the compounds were established based on the spectral studies. All the piperdin-4-ol derivatives (7-12) were assayed for antibacterial, antifungal and anthelmintic activities and they exhibited significant results.
journal_name
Nat Prod Resjournal_title
Natural product researchauthors
Maruthavanan T,Venkatesan Pdoi
10.1080/14786419.2012.671317subject
Has Abstractpub_date
2013-01-01 00:00:00pages
238-45issue
3eissn
1478-6419issn
1478-6427journal_volume
27pub_type
杂志文章abstract::The leaves of Alchornea floribunda and Alchornea cordifolia are used traditionally as topical anti-inflammatory agents. In this study, two highly lipophilic fractions AFLF and ACLF isolated from A. floribunda and A. cordifolia leaves respectively were investigated for topical anti-inflammatory effects using xylene-ind...
journal_title:Natural product research
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journal_title:Natural product research
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