Thujasutchins N and O, two new compounds from the stems and roots of Thuja sutchuenensis.

Abstract:

:Two novel secondary metabolites, including one thujopsene-type sesquiterpene designated thujasutchin N (1) and one norlignan named thujasutchin O (2) were obtained from the ethanolic extract of the stems and roots of Thuja sutchuenensis. Among them, thujasutchin O (2) represents the first example of lignan sharing a unique carbon-reduced skeleton with novel acetal functionality. Their structures were unambiguously determined by means of extensively spectroscopic analysis including UV, IR, HRESIMS, NMR, and single crystal X-ray diffraction. Both of the isolates were evaluated for their in vitro cytotoxic and antibacterial activities.

journal_name

Nat Prod Res

journal_title

Natural product research

authors

Wang M,Huo L,Liu H,Zhao L,Xu Z,Tan H,Qiu SX

doi

10.1080/14786419.2020.1836627

subject

Has Abstract

pub_date

2020-10-23 00:00:00

pages

1-7

eissn

1478-6419

issn

1478-6427

pub_type

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