Abstract:
:A 70% ethanol extract from the leaves of Rosa davurica showed significant antioxidant activity in both superoxide anion and 1,1-diphenyl-2-picrylhydrazyl (DPPH) free radical-scavenging assays. Phytochemical study of this extract resulted in the isolation of eight compounds, including a new flavonoid glycoside. The chemical structure was determined by various spectroscopic analyses. The isolated compounds and their structurally related compounds, belonging to two classes: quercetin 3-O-glycosides and gallic acid derivates, were evaluated for their superoxide anion- and DPPH free radical-scavenging activities. These compounds showed significant superoxide anion-scavenging activity with the EC50 values ranging from 1.68 to 18.09 μM, and DPPH free radical-scavenging activity with the EC50 values ranging from 7.18 to 67.62 μM. The structure-activity relationship was also reported.
journal_name
Nat Prod Resjournal_title
Natural product researchauthors
Ma F,Onoda T,Li W,Sasaki T,Ma L,Zhang Q,Koike Kdoi
10.1080/14786419.2013.811408subject
Has Abstractpub_date
2013-01-01 00:00:00pages
2178-82issue
23eissn
1478-6419issn
1478-6427journal_volume
27pub_type
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