Chemistry of α-mangostin. Studies on the semisynthesis of minor xanthones from Garcinia mangostana.

Abstract:

:α-Mangostin is the major prenylated xanthone from Garcinia mangostana and it has been used also in recent times as starting material for the semisynthetic preparation of various biologically active derivatives. Its structure is characterised by the presence of few functional groups amenable to chemical manipulations, but present in the molecule in multiple instances (three phenolic hydroxyl groups, two prenyl chains and two unsubstituted aromatic carbons). This study represents a first approach to the systematic investigation of the reactivity of α-mangostin and describes the semisynthesis of some minor xanthones isolated from G. mangostana.

journal_name

Nat Prod Res

journal_title

Natural product research

authors

Morelli CF,Biagiotti M,Pappalardo VM,Rabuffetti M,Speranza G

doi

10.1080/14786419.2014.986729

subject

Has Abstract

pub_date

2015-01-01 00:00:00

pages

750-5

issue

8

eissn

1478-6419

issn

1478-6427

journal_volume

29

pub_type

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