Bioactive mushroom polysaccharides as antitumor: an overview.


:Immuno-therapies are gaining more importance to treat certain forms of cancer. The goal of therapies is to enhance person's own IgG, IgA, IgM, IgD, IgE and macrophages to combat with neoplastic cells hence the effectiveness of the immune system. Since, early civilization mushrooms are considered as potent food as well as medicine. Mushrooms are well known for their bioactive compounds such as chizophyllan, lentinan, grifolan, PSP (polysaccharide-peptide complex) and PSK (polysaccharide-protein complex) which are considered as medicines against melignancy. They prevent oncogenesis by the direct effect on tumor metastasis and exhibits antitumor effects by the induction of immune response in host. Mushroom polysaccharides have promising future for treatment of cancers due to their mode of action and efficacy. Also there are some hurdles during this treatment, but it will start a new era of safer and effective medicine based on mushroom polysaccharides.


Nat Prod Res


Natural product research


Pandya U,Dhuldhaj U,Sahay NS




Has Abstract


2019-09-01 00:00:00












  • Chemical variability in the essential oil of Cinnamomum tamala L. leaves from India.

    abstract::The chemical composition of the essential oils obtained from the fresh leaves of Cinnamomum tamala Nees et Eberm. was determined by GC and GC-MS. The yield of the oil on a dry weight basis ranged from 1.2% to 3.9% (w/w). Phenyl propanoids constitute the major portion (88.9-95.0%) of the oils. Fifty-four compounds were...

    journal_title:Natural product research

    pub_type: 杂志文章


    authors: Rana VS,Langoljam RD,Verdeguer M,Blázquez MA

    更新日期:2012-01-01 00:00:00

  • Antioxidant activity and two new flavonoids from Washingtonia filifera.

    abstract::Two new flavonoids, 8-hydroxyisoscoparin (1) and luteolin 7-O-glucoside 4''-sulfate (2), along with eight known flavonoids, including luteolin 7-O-glucoside 2''-sulfate, were isolated and identified from Washingtonia filifera. All compounds were characterized by (1)H-NMR, (13)C-NMR, CI-MS, FABMS and UV. The antioxidan...

    journal_title:Natural product research

    pub_type: 杂志文章


    authors: El-Sayed NH,Ammar NM,Al-Okbi SY,El-Kassem LT,Mabry TJ

    更新日期:2006-01-01 00:00:00

  • Polyphenolics from Gymnocarpos decandrus Forssk roots and their biological activities.

    abstract::Phytochemical investigation of Gymnocarpos decandrus roots lead to the isolation, characterization and evaluation of four compounds: the bis-coumarin daphnoretin, two biflavonoids: wikstrol A and wikstol B in addition to β-sitosterol glucoside. Their structures were established via spectroscopic data. The crude root e...

    journal_title:Natural product research

    pub_type: 杂志文章


    authors: Fathy H

    更新日期:2019-05-13 00:00:00

  • Chemical composition and antimicrobial evaluation of the essential oils of Bocageopsis pleiosperma Maas.

    abstract::Essential oils from the leaves, twigs and barks of Bocageopsis pleiosperma Maas were obtained by using hydrodistillation and analysed by using gas chromatography coupled to mass spectrometry. Several compounds (51) were detected and identified, being β-bisabolene the main component in all aerial parts of the plant, wi...

    journal_title:Natural product research

    pub_type: 杂志文章


    authors: Soares ER,da Silva FM,de Almeida RA,de Lima BR,Koolen HH,Lourenço CC,Salvador MJ,Flach A,da Costa LA,de Souza AQ,Pinheiro ML,de Souza AD

    更新日期:2015-01-01 00:00:00

  • The essential oils of the aerial parts of two Hypericum taxa (Hypericum triquetrifolium and Hypericum aviculariifolium subsp. depilatum var. depilatum (Clusiaceae)) from Turkey.

    abstract::In this study, essential oil compositions of two Hypericum L. taxa (Hypericum triquetrifolium Turra. and Hypericum aviculariifolium Jaub. et Spach subsp. depilatum var. depilatum (Freyn et Bornm.) Robson) naturally grown in Turkey were determined using gas chromatography and gas chromatography-mass spectrometry system...

    journal_title:Natural product research

    pub_type: 杂志文章


    authors: Yuce E,Bagci E

    更新日期:2012-11-01 00:00:00

  • Interest of ferulic acid ethyl ester in photoprotective creams: measure of efficacy by in vitro method.

    abstract::Topical sunscreens have been used for many years on exposed areas to protect the skin from the damaging effects of ultraviolets. If the sunscreens were essential, it is suggested that they have adverse effects. We chose to study ferulic acid ethyl ester (FAEE) as agent which could potentially be used in sunscreen prod...

    journal_title:Natural product research

    pub_type: 杂志文章


    authors: Choquenet B,Couteau C,Paparis E,Coiffard LJ

    更新日期:2008-01-01 00:00:00

  • A new oleanolic-type triterpene glycoside from Anchusa italica.

    abstract::A new oleanolic-type triterpene glycoside, (3β,21β)-21-[(β-d-glucopyranosyl-(1→2)-β-d-glucopyranosyl)oxy]-3-hydroxyolean-12-en-28-oic acid (1), together with five analogues, oleanazuroside 1 (2), oleanazuroside 2 (3), 24-hydroxytormentic acid ester glucoside (4), 24-epi-pinfaensin (5), and oleanolic acid 3-O-α-l-arabi...

    journal_title:Natural product research

    pub_type: 杂志文章


    authors: Chen KK,Xie ZJ,Dai W,Wang Q

    更新日期:2017-04-01 00:00:00

  • Hypoglycaemic activity of saponin fraction extracted from Momordica charantia in PEG/salt aqueous two-phase systems.

    abstract::Momordica charantia (family, Cucurbitaceae), commonly known as karela or bitter melon (Japanese name 'Tsurureishi'), is used as a folk medicine in China, the Indian subcontinent and South America. In Chinese traditional medicine, the plant is usually used as a hypoglycaemic and anti-diabetic agent. The hypoglycaemic a...

    journal_title:Natural product research

    pub_type: 杂志文章


    authors: Han C,Hui Q,Wang Y

    更新日期:2008-01-01 00:00:00

  • (±) Benzomalvins E isolated from Penicillium sp. SYPF 8411 in the rhizosphere soil of Codonopsis clematidea.

    abstract::(+) Benzomalvins E (1) and (-) Benzomalvins E (2), a pair of epimeric derivatives, together with three known benzomalvins (3-5), were isolated from solid cultures of a interrhizospheric fungus Penicillium sp. SYPF 8411. The planar structure of (+) Benzomalvins E (1) has been previously reported. While, the absolute co...

    journal_title:Natural product research

    pub_type: 杂志文章


    authors: Feng QM,Feng Y,Zhang TY,Wang HF,Zhang MY,Wu YY,Chen G,Zhang YX,Pei YH

    更新日期:2020-07-01 00:00:00

  • Enhancement of phenolic content, antioxidant and cytotoxic activities of Moringa oleifera leaf and seed by suspension culture.

    abstract::Moringa oleifera Lam. family Moringaceae is well known for a wide range of biological activities and a complex phytochemical composition. The current study investigates tissue culture protocols for Moringa oleifera leaves and seeds. For static culture initiation, Murashige and skooge (MS) as a basal medium with hormon...

    journal_title:Natural product research

    pub_type: 杂志文章


    authors: Mustafa R,El-Naggar EMB,Svajdlenka E,Omran G,ELFiky F,El-Hawiet A

    更新日期:2020-03-25 00:00:00

  • Modulation of Paecilomyces lilacinus antimicrobial metabolite production by co-culturing with Salmonella typhimurium.

    abstract::Fungi are important organisms related to the production of antibiotics, many of which are commercially available and used in the clinic to treat infections. Infectious diseases represent a leading cause of death worldwide, being a severe threat to public health, especially with the rise of multi-resistant microorganis...

    journal_title:Natural product research

    pub_type: 杂志文章


    authors: Teles AP,Ataliba GS,Takahashi JA

    更新日期:2013-01-01 00:00:00

  • Polyol monoterpenes isolated from Chenopodium ambrosioides.

    abstract::Phytochemical study on the 95% ethyl alcohol extract of stems of Chenopodium ambrosioides resulted in the isolation of two new polyol monoterpenes, 4-hydroxy-4(α or β)-isopropyl-2-methyl-2-cyclohexen-1-one (1) and 1-methyl-4β- isopropyl-1-cyclohexene-4α,5α,6α-triol (2), together with five known compounds, (1S,2S,3R,4S...

    journal_title:Natural product research

    pub_type: 杂志文章


    authors: Hou SQ,Li YH,Huang XZ,Li R,Lu H,Tian K,Ruan RS,Li YK

    更新日期:2017-11-01 00:00:00

  • Cytotoxic xanthones from the plant endophytic fungus Paecilamyces sp. TE-540.

    abstract::One new xanthone, chryxanthone C (1), together with four known analogues (2-5), were isolated from the cultures of Paecilamyces sp. TE-540, an endophytic fungus obtained from the leaves of Nicotiana tabacum L. The structure of 1 was elucidated by comprehensive spectral analysis including HRESIMS and 1D/2D NMR, which w...

    journal_title:Natural product research

    pub_type: 杂志文章


    authors: Li XQ,Dong QJ,Xu K,Yuan XL,Liu XM,Zhang P

    更新日期:2020-10-04 00:00:00

  • New monoterpene glycosides from the root cortex of Paeonia suffruticosa and their potential anti-inflammatory activity.

    abstract::The methanol extract of the root cortex of Paeonia suffruticosa afforded two new monoterpene glycosides, paeoniside A (1) and paeoniside B (2), and three known monoterpene glycosides, paeoniflorin (3), benzoylpaeoniflorin (4) and 4-O-methyl-paeoniflorin (5). Their structures were elucidated on the basis of spectroscop...

    journal_title:Natural product research

    pub_type: 杂志文章


    authors: Zhu X,Fang ZH

    更新日期:2014-01-01 00:00:00

  • Phytochemical analysis in Alternanthera brasiliana by LC-MS/MS and GC-MS.

    abstract::Alternanthera brasiliana is popularly known as 'penicillin' and used as an anti-inflammatory and for wound healing. The objective of this work was the phytochemical study of the species by analytical techniques such as LC-MS/MS and GC-MS. Twenty-seven compounds were identified, five by LC-MS and 22 by GC-MS analysis. ...

    journal_title:Natural product research

    pub_type: 杂志文章


    authors: Alencar Filho JMT,Teixeira HAP,Sampaio PA,Pereira ECV,Amariz IAE,Rolim Neto PJ,Rolim LA,Araújo ECDC

    更新日期:2020-02-01 00:00:00

  • Anti-inflammatory monoterpene esters from the stems of Illigera aromatica.

    abstract::Two new monoterpene esters illigerates F and G (1 and 2) together with 5 know compounds illigerate A (3), illigerate C (4), actinodaphnine (5), N-methylactinodaphnine(6) and N-methyllaurotetanine(7) were isolated from Illigera aromatica S. Z. Huang et S. L. Mo. Their structures were identified by extensive NMR data an...

    journal_title:Natural product research

    pub_type: 杂志文章


    authors: Pu XY,Tian K,Sun JX,Wang W,Liu HC,Yang J,Jiang MY,Huang XZ

    更新日期:2019-05-28 00:00:00

  • Design and synthesis of novel hydrocarbylidene nitrohydrazinecarboximidamides against aphids based on natural product galegine.

    abstract::A series of novel hydrocarbylidene nitrohydrazinecarboximidamides were designed and synthesized using an insecticidal natural product Galegine as a lead compound. The bioassay results show that the target compounds exhibited moderate to good insecticidal activities against Hyalopterus pruni Geoffroy at a concentration...

    journal_title:Natural product research

    pub_type: 杂志文章


    authors: Wu Q,Zhao F,Zhu X,Zhou Z,Yang D,Xu Z,Li J,Qin Z

    更新日期:2019-08-20 00:00:00

  • A new diacylglycerol from fresh olive pulp.

    abstract::The isolation from olive pulp of a diacylglycerol showing an oleic as well as an elenoic acid residue, the latter probably derived from a natural enzymatic oleuropein hydrolysis, is reported. The given structure is supported by 1H- and 13C-NMR data. ...

    journal_title:Natural product research

    pub_type: 杂志文章


    authors: Marra C,Giordano ME

    更新日期:2005-01-01 00:00:00

  • Plants of the Russian Federation pharmacopeia: an unexhausted natural products research opportunity?

    abstract::32 medicinal plants that are unique to the Russian Pharmacopeia have 693 isolated natural products associated with them (an average of 21.66 compounds per plant). This is in contrast to the US Pharmacopeia plants that have delivered 2366 known natural products (an average of 42.25 compounds per plant). ...

    journal_title:Natural product research

    pub_type: 信件


    authors: Chupakhin E,Babich O,Prosekov A,Asyakina L,Gureev M,Krasavin M

    更新日期:2020-02-21 00:00:00

  • Synthesis of C17-[5-methyl-1,3]-oxazoles by N-propargylation of triterpenic acids and evaluation of their cytotoxic activity.

    abstract::A series of unexpected triterpenic C17-[5-methyl-1,3]-oxazoles along with targeted N-propargylamides was synthesized by an interaction of acid chlorides with propargylamine hydrochloride. We proposed that the formation of methyl oxazole passes through an alternative pathway by the participation of the terminal alkyne ...

    journal_title:Natural product research

    pub_type: 杂志文章


    authors: Khusnutdinova EF,Petrova AV,Lobov AN,Kukovinets OS,Baev DS,Kazakova OB

    更新日期:2020-03-28 00:00:00

  • Chemical composition of essential oils from the vegetative and reproductive structures of Copaifera langsdorffii Desf.

    abstract::GC/FID and GC-MS analysis revealed germacrene D, bicyclogermacrene, α-cadinol and cubenol as major compounds from aril. Germacrene D, bicyclogermacrene, trans-caryophyllene and δ-elemene are major compounds in fruits. Germacrene D, spathulenol, trans-caryophyllene and caryophyllene oxide are major compounds in leaves....

    journal_title:Natural product research

    pub_type: 杂志文章


    authors: Portella Rde O,Facanali R,Marques MO,de Almeida LF

    更新日期:2015-01-01 00:00:00

  • Hypogymnia tubulosa extracts: chemical profile and biological activities.

    abstract::This study reports for the first time in the chemical composition of acetone, ether, ethyl acetate and dichloromethane extracts of Hypogymnia tubulosa determined by HPLC-UV, GC-FID and GC-MS as well as effect of H. tubulosa acetone extract on micronucleus distribution on human lymphocytes and on cholinesterase activit...

    journal_title:Natural product research

    pub_type: 杂志文章


    authors: Stojanović G,Zlatanović I,Zrnzević I,Stanković M,Stankov Jovanović V,Zlatković B

    更新日期:2018-11-01 00:00:00

  • Identification and antimicrobial properties of a new alkaloid produced by marine-derived Verrucosispora sp. FIM06-0036.

    abstract::The actinomycete strain FIM06-0036 was isolated from marine sponge sample collected from the East China Sea and identified as Verrucosispora sp. based upon the results of 16S rRNA sequence analysis. One new alkaloid, 2-ethylhexyl 1H-imidazole-4-carboxylate (1), together with a known alkaloid butyl 1H-imidazole-4-carbo...

    journal_title:Natural product research

    pub_type: 杂志文章


    authors: Chen MH,Lian YY,Fang DS,Chen L,Jia J,Zhang WL,Lin R,Xie Y,Bi HK,Jiang H

    更新日期:2019-11-15 00:00:00

  • Unexpected formation of hydroxybiphenylmethane derivatives and some new observations on Labat test.

    abstract::An unexpected synthesis of symmetrical hydroxybiphenylmethanes involving the reaction of 2-hydroxyphenyl benzyl ketones with ethoxymethyl chloride has been observed. Some new interesting observations of Labat test on colorimetric detection of bichalconyloxy, bichalconyl and biflavonylmethanes having oxygenated ortho p...

    journal_title:Natural product research

    pub_type: 杂志文章


    authors: Kukreja G,Campiani G,Khurana JM,Joshi BP,Grover SK

    更新日期:2006-10-01 00:00:00

  • Hexane fraction from Brazilian Morus nigra leaves improved oral carbohydrate tolerance and inhibits α-amylase and α-glucosidase activities in diabetic mice.

    abstract::Morus nigra, popularly known as mulberry, has been traditionally used as anti-diabetic herbal medication. This study focused on hexane fraction from Brazilian M. nigra leaves (Hex-Mn) effects on digestion and absorption of carbohydrate in diabetic mice. The high-performance liquid chromatography (HPLC) analysis was pe...

    journal_title:Natural product research

    pub_type: 杂志文章


    authors: Silva DHAD,Barbosa HM,Beltrão RLA,Silva CFO,Moura CA,Castro RN,Almeida JRGDS,Gomes DA,Lira EC

    更新日期:2020-02-24 00:00:00

  • Monoterpene glycosides from Indigofera hetrantha.

    abstract::Monoterpene glycosides have been isolated from the ethyl acetate soluble fraction of Indigofera hetrantha and their structures assigned to be 3,7-dimethyl-2(E),6-octadien-5-one-1-O-beta-D-6-O-acetylglucopyranoside (1) and 3,7-dimethyl-2(E), 6-octadien-5-one-1-O-[-beta-D-6''-O-acetylglucopyra-nosyl (1'' --> 6')-beta-D-...

    journal_title:Natural product research

    pub_type: 杂志文章


    authors: Mehmood S,Aziz-Ur-Rahman,Ahmad Z,Afza N,Malik A,Ahmad H,Choudhary MI

    更新日期:2008-01-01 00:00:00

  • Anthraquinones from Morinda officinalis roots enhance adipocyte differentiation in 3T3-L1 cells.

    abstract::To search for anti-diabetic and insulin-sensitising natural products, the effect on adipocyte differentiation was investigated by assessing fat accumulation in 3T3-L1 preadipocytes using Oil Red O staining. Fractionation and separation of n-hexane and CHCl₃ fractions of Morinda officinalis (Rubiaceae) using several ch...

    journal_title:Natural product research

    pub_type: 杂志文章


    authors: Liu Q,Kim SB,Ahn JH,Hwang BY,Kim SY,Lee MK

    更新日期:2012-01-01 00:00:00

  • Microcalorimetric study of the effect of Benzoinum and Styrax on the growth of Escherichia coli.

    abstract::In this study, the effects of Benzoinum and Styrax on Escherichia coli (E. coli) growth were investigated by microcalorimetry. Using a TAM Air Isothermal Calorimeter, ampoule method, the power-time curves of E. coli growth at 37°C affected by Benzoinum and Styrax were measured. By analysing some quantitative thermokin...

    journal_title:Natural product research

    pub_type: 杂志文章


    authors: Wang J,Cheng D,Zeng N,Xia H,Fu Y,Yan D,Zhao Y,Xiao X

    更新日期:2011-02-01 00:00:00

  • Effect of Asteracantha longifolia seeds on the sexual behaviour of male rats.

    abstract::The aim of the present study was to study the effect of seeds of Asteracantha longifolia on the sexual behaviour of male albino rats. The ethanolic extract of seeds of A. longifolia was administered to groups of rats in 100, 150 and 200 mg kg⁻¹ doses for a period of 28 days, and the action compared with control rats. ...

    journal_title:Natural product research

    pub_type: 杂志文章


    authors: Chauhan NS,Sharma V,Dixit VK

    更新日期:2011-09-01 00:00:00

  • Search for antibacterial agents from Malaysian rainforest and tropical plants.

    abstract::The world's rainforests hold untold potential for drug discovery. Rainforest plants are thought to contain evolved defensive active metabolites of greater diversity compared to plants from temperate regions. In recent years, the interest and overall output from pharmaceutical companies on novel antibacterial agents ha...

    journal_title:Natural product research

    pub_type: 杂志文章


    authors: Othman M,Genapathy S,Liew PS,Ch'ng QT,Loh HS,Khoo TJ,Wiart C,Ting KN

    更新日期:2011-11-01 00:00:00