Bioactive mushroom polysaccharides as antitumor: an overview.

abstract：:Protein kinase C (PKC) plays a key role in neurotransmission in the central nervous system, and targeting PKC domain is considered as a strategy to modulate the anaesthetic effects. In this study, we described a synthetic pipeline to perform high-throughput virtual screening against a large library of 3D structural na...

journal_title：Natural product research

authors： Zhao J,Zhou C

更新日期：2015-01-01 00:00:00

abstract：:The phytochemical constituents in the aqueous methanolic leaf extract of Triclisia gilletii responsible for its nephroprotective potentials against ethane-1,2-diol induced nephrolithiasis as previously investigated in our laboratory were elucidated. The extract was prepared using 80% aqueous methanol in 72 h, Phytoche...

journal_title：Natural product research

authors： Olayeriju OS,Papetti A,Colombo R,Mannucci B,Olaleye MT,Akindahunsi AA

更新日期：2020-11-12 00:00:00

abstract：:In order to identify genes related to Taxol biosynthesis, the mRNA differential display method was employed to compare mRNA populations from suspension cultured Taxus chinensis cells before and after beginning to produce Taxol. From a total display of about 4000 PCR products, 104 were derived from cells during the Tax...

journal_title：Natural product research

authors： Hu G,Fan T,Mei X

更新日期：2004-08-01 00:00:00

abstract：:A novel aromatic compound, grandiuvarone B (5-acetoxy-3-benzoyloxymethyl-5H-oxepin-4-one), along with a known compound grandiuvarone A (5-acetoxy-6-benzoyloxymethyl-5H-oxepin-4-one) were isolated from methanol extracts of Desmos chinensis leaves. Their structures were determined by various spectroscopic techniques inc...

journal_title：Natural product research

authors： Zhi QQ,Yan QH,Wang Q,Sun PF,Zhou HY,He ZM

更新日期：2020-04-01 00:00:00

abstract：:The ethanolic extract of the bulbs of Fritillaria imperialis was subjected to fractionation by solvent-solvent extraction. The nonpolar fraction showed inhibitory activity against prolyl endopeptidase (PEP) (EC.3.4.21.26), a large intracellular enzyme that preferentially hydrolyze proline-containing oligopeptidase at ...

journal_title：Natural product research

authors： Atta-ur-Rahman,Akhtar MN,Choudhary MI,Tsuda Y,Yasin A,Sener B,Parvez M

更新日期：2005-01-01 00:00:00

abstract：:One new indole alkaloid (1) and one new indole alkaloidal glycoside (2), together with nine known alkaloids (3-11), were isolated from the leaves of Evodia rutaecarpa. Their structures were determined on the basis of spectroscopic and chemical methods. Compound 4 exhibited potent activity against Pseudomonas aeruginos...

journal_title：Natural product research

authors： Xia X,Luo JG,Liu RH,Yang MH,Kong LY

更新日期：2016-10-01 00:00:00

abstract：:In the present study, hydroxy-2-methyl-4H-pyran-4-one was isolated from the methanol root extract of Senecio laetus and was identified by FT-IR, 1H, 13C NMR and GC-MS. The larvicidal potential of the compound 3-hydroxy-2-methyl-4H-pyran-4-one was evaluated against the 4th instar larvae of Anopheles stephensi, Aedes ae...

journal_title：Natural product research

authors： Ali SI,Venugopalan V

更新日期：2019-06-27 00:00:00

abstract：:A new protostane-type triterpenoid bearing an oxetane ring in the side-chain, named alisol W (1), has been obtained from the dried rhizome of Alisma plantago-aquatica subsp. orientale. The structure and absolute configuration of compound 1 was determined from extensive spectroscopic analysis. In addition, the vasorela...

journal_title：Natural product research

authors： Li HM,Liu D,Dai WF,Chen XQ,Li RT

更新日期：2019-11-01 00:00:00

abstract：:A new isopimarane-type diterpenoid, crolaevinoid A, along with four known analogues was isolated from the twigs and leaves of Croton laevigatus. The structures of the isolated compounds were established on the basis of NMR and MS spectroscopic analyses. The isolated compounds were examined the antibacterial activities...

journal_title：Natural product research

authors： Li MY,Han ZZ,Liu LF,Wu XZ,Huang WJ,Wang K,Yang F,Yuan CS

更新日期：2020-10-01 00:00:00

abstract：:Our laboratories have been investigating biological effects of a sesquiterpenoid polygodial and its natural and synthetic analogues. Herein, we report the evaluation of these compounds against the three forms of Trypanosoma cruzi, amastigotes, trypomastigotes and epimastigotes. Although polygodial was found to be poor...

journal_title：Natural product research

authors： Turner DN,Just J,Dasari R,Smith JA,Bissember AC,Kornienko A,Rogelj S

更新日期：2019-04-28 00:00:00

abstract：:An actinomycete strain 200-09, isolated from a soil sample collected from the coast of Hawaii, USA, was identified as Streptomyces antibioticus on the basis of its morphological, physiological and biochemical characteristics as well as 16S rDNA analysis. A new antimycin-type antibiotic, kitamycin C (1), together with ...

journal_title：Natural product research

authors： Wang F,Fu SN,Bao YX,Yang Y,Shen HF,Lin BR,Zhou GX

更新日期：2017-08-01 00:00:00

abstract：:Bioassay guided chemical investigation of the gorgonian Pacifigorgia senta led to the discovery of a new 19-oxygenated steroid, cholesta-5,24-diene-3β,7β,19-triol (1), as well as three known steroids (2-4). The structure of 1 was determined by extensive spectroscopic analysis, including NMR and MS spectra. All of the ...

journal_title：Natural product research

authors： Chen M,Han L,Zhang XL,Wang CY

更新日期：2016-06-01 00:00:00

abstract：:This work was carried out to study the effect of topical application of Andrographis paniculata on the rate of wound enclosure and its histological features. A wound was created in four groups of rat in posterior neck region. Blank placebo was applied topically to the wounds of Group 1. Groups 2 and 3 were dressed wit...

journal_title：Natural product research

authors： Al-Bayaty FH,Abdulla MA,Abu Hassan MI,Ali HM

更新日期：2012-01-01 00:00:00

abstract：:Present research reports the molecular docking analysis of 2019-nCoV inhibition by antiviral compounds from marine natural resources. For this study, the structure of ligand (antiviral compound) and 2019-nCoV main protease (Mpro) was received from the databases of PubChem and Protein Data Bank (PDB), respectively. Mol...

journal_title：Natural product research

authors： Vijayaraj R,Altaff K,Rosita AS,Ramadevi S,Revathy J

更新日期：2020-07-09 00:00:00

abstract：:Ginsenoside Re (G-Re) is a major ingredient of the ginseng bud. A novel and rapid method to isolate and purify G-Re from ginseng buds was established. The procedure involves solvent extraction of ginseng bud powder, then pre-purification with an active carbon column and purification by preparative HPLC (prep-HPLC). Ac...

journal_title：Natural product research

authors： Kuang P,Wang G,Yuan Q,Liang H

更新日期：2012-01-01 00:00:00

abstract：:The phytochemical study of the aerial parts of Viburnum chinshanense Graebn., a species growing in Western and Central China, led to the isolation of six iridoid glucosides: the novel 10,2'-diacetylpatrinoside, 1, and the known 2'-acetyldihydropenstemide, 2'-trans- p-coumaroyl-dihydropenstemide, 2'-acetylpatrinoside, ...

journal_title：Natural product research

authors： Tomassini L,Gao J,Foddai S,Serafini M,Ventrone A,Nicoletti M

更新日期：2006-07-10 00:00:00

abstract：:A phytochemical reinvestigation of the whole plant of Euphorbia segetalis yielded five tetracyclic triterpenes: 3beta-hydroxy-cycloart-25-en-24-one (1), cycloart-25-ene-3beta,24-diol (2), cycloart-23-ene-3beta,25-diol (3), lanosta-7,9(11),24-trien-3beta-ol (4) and lanosta-7,9(11),24(31)-trien-3beta-ol (5). beta-acetox...

journal_title：Natural product research

authors： Madureira AM,Ascenso JR,Valdeira L,Duarte A,Frade JP,Freitas G,Ferreira MJ

更新日期：2003-10-01 00:00:00

abstract：:Epicatechin (EC) is the most effective compound in Euonymus alatus (Thunb.)Sieb, and possesses a series of benefits, including anti-inflammatory, antioxidant, antiobesity and anticancer effects. In this study, we investigated the protective effects of EC in Acetaminophen(N-acetyl-p-aminophenol, APAP)-induced acute liv...

journal_title：Natural product research

authors： Wu H,Xie Y,Xu Y,Hu Z,Wan X,Huang H,Huang D

更新日期：2020-03-01 00:00:00

abstract：:The iridoidic composition of Stachys glutinosa L. was examined in comparison with the results obtained in the phytochemical studies on S. corsica Pers. The presence of the known harpagide and acetyl-harpagide were showed together with that of a new di-glycosidic iridoid. The structure of this new compound, the 5-allos...

journal_title：Natural product research

authors： Serrilli AM,Ramunno A,Piccioni F,Serafini M,Ballero M,Bianco A

更新日期：2006-05-20 00:00:00

abstract：:Tectona grandis Linn (Teak), is locally known as Sagwan, belongs to Lamiaceae family. It is one of the most valuable timber in the world, due to its beautiful surface and its resistance to termite and fungal damage. The main active ingredient compounds that are responsible for these action are tectoquinone, lapachol a...

journal_title：Natural product research

authors： Vyas P,Yadav DK,Khandelwal P

更新日期：2019-08-01 00:00:00

abstract：:To obtain more accessible oxidative stress inhibitors, a series of novel spin-labelled derivatives of 3-hydroxybutanolide (2a-d, 3a-d) with the natural active compound (kinsenoside) as the lead compound were designed, synthesised from the nitroxide free radical piperidine (pyrroline) and the main structural unit of ki...

journal_title：Natural product research

authors： Liu Q,Liu ZL,Tian J,Shi W,Liu YQ

更新日期：2014-01-01 00:00:00

abstract：:A new γ-pyrone derivative, acrepyrone A (1), and three known sorbicillinoids, trichodimerol (2), dihydrotrichodimerol (3) and tetrahydrotrichodimerol (4) were isolated from an endophytic fungus, Acremonium citrinum SS-g13, harboured in the roots of the Chinese medicinal plant Fructus mori. Their structures were determ...

journal_title：Natural product research

authors： Peng XP,Li G,Ji LX,Li YX,Lou HX

更新日期：2020-04-01 00:00:00

abstract：:Eight known abietane diterpenes (1-8) were isolated for the first time from Abies numidica cones (Pinaceae). The structures of all compounds were established by means of 1D and 2D NMR, and UV spectral analyses. The hydromethanolic extract of A. numidica cones was tested for its antimicrobial activity against 17 gram-p...

journal_title：Natural product research

authors： Belhadj Mostefa M,Abedini A,Voutquenne-Nazabadioko L,Gangloff SC,Kabouche A,Kabouche Z

更新日期：2017-03-01 00:00:00

abstract：:The investigation on the stems and leaves of Clausena lenis led to the isolation of a previously undescribed carbazole alkaloid, clausenalenine A (1), along with seven known analogues (2-8). The structure of 1 was elucidated based on comprehensive spectroscopic analyses and the known compounds were identified by compa...

journal_title：Natural product research

authors： Yan G,Li YJ,Zhao YY,Guo JM,Zhang WH,Zhang MM,Fu YH,Liu YP

更新日期：2019-09-16 00:00:00

abstract：:The purpose of this study is the determination of chemical composition and antioxidant activity of essential oils (EOs) from Saussurea costus (Falc.) Lipsch. Roots have been collected on December of the first plant year (IY) and in April, August and December of the third plant year (I, 6B, D7). A GC analysis was carri...

journal_title：Natural product research

authors： Benedetto C,D'Auria M,Mecca M,Prasad P,Singh P,Singh S,Sinisgalli C,Milella L

更新日期：2019-08-01 00:00:00

abstract：:The aim of the present study was to study the effect of seeds of Asteracantha longifolia on the sexual behaviour of male albino rats. The ethanolic extract of seeds of A. longifolia was administered to groups of rats in 100, 150 and 200 mg kg⁻¹ doses for a period of 28 days, and the action compared with control rats. ...

journal_title：Natural product research

authors： Chauhan NS,Sharma V,Dixit VK

更新日期：2011-09-01 00:00:00

abstract：:Phytochemical study on the 95% ethyl alcohol extract of stems of Chenopodium ambrosioides resulted in the isolation of two new polyol monoterpenes, 4-hydroxy-4(α or β)-isopropyl-2-methyl-2-cyclohexen-1-one (1) and 1-methyl-4β- isopropyl-1-cyclohexene-4α,5α,6α-triol (2), together with five known compounds, (1S,2S,3R,4S...

journal_title：Natural product research

authors： Hou SQ,Li YH,Huang XZ,Li R,Lu H,Tian K,Ruan RS,Li YK

更新日期：2017-11-01 00:00:00

abstract：:A new hexadienamide derivative named sarmentosamide (1) was identified from the culture of Streptomyces sp. SBI108 isolated from Thai soil under an herb. The structure was elucidated on the basis of spectroscopic data, and the absolute configuration was determined by chemical degradation. ...

journal_title：Natural product research

authors： Kitani S,Tomio A,Srichaisupakit A,Daduang R,Intra B,Panbangred W,Oku N,Igarashi Y,Nihira T

更新日期：2013-01-01 00:00:00

abstract：:A new triterpene saponin (1) was isolated from a methanol extract of Swartzia apetala Raddi var. glabra, together with the flavonoids mauritianin (2), kaempferol (3) and the triterpene saponin β-D-glucopyranosyl 3β-hydroxy-olean-12-en-28-oate (4). These compounds were characterised on the basis of their spectral data,...

journal_title：Natural product research

authors： de Araújo MF,Curcino Vieira IJ,Sant'Anna CM,da Silva DR,Vitorino Maia AI,Braz-Filho R,Vieira-da-Motta O,Mathias L

更新日期：2013-10-01 00:00:00

abstract：:Two new triterpene saponins, namely notoginsenoside Ng5 (1) and notoginsenoside Ng6 (2) were isolated from the leaves of Panax notoginseng, along with five known ones. Their structures were determined by chemical methods, NMR and X-ray experiments. The absolute configuration of compound 3 with four sugar units was con...

journal_title：Natural product research

authors： Huang JW,Du YQ,Li CJ,Yang JZ,Ma J,Zang YD,Chen NH,Zhang DM

更新日期：2019-10-22 00:00:00