Bioactive mushroom polysaccharides as antitumor: an overview.

Abstract:

:Immuno-therapies are gaining more importance to treat certain forms of cancer. The goal of therapies is to enhance person's own IgG, IgA, IgM, IgD, IgE and macrophages to combat with neoplastic cells hence the effectiveness of the immune system. Since, early civilization mushrooms are considered as potent food as well as medicine. Mushrooms are well known for their bioactive compounds such as chizophyllan, lentinan, grifolan, PSP (polysaccharide-peptide complex) and PSK (polysaccharide-protein complex) which are considered as medicines against melignancy. They prevent oncogenesis by the direct effect on tumor metastasis and exhibits antitumor effects by the induction of immune response in host. Mushroom polysaccharides have promising future for treatment of cancers due to their mode of action and efficacy. Also there are some hurdles during this treatment, but it will start a new era of safer and effective medicine based on mushroom polysaccharides.

journal_name

Nat Prod Res

journal_title

Natural product research

authors

Pandya U,Dhuldhaj U,Sahay NS

doi

10.1080/14786419.2018.1466129

subject

Has Abstract

pub_date

2019-09-01 00:00:00

pages

2668-2680

issue

18

eissn

1478-6419

issn

1478-6427

journal_volume

33

pub_type

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