Bioactive compounds from marine resources against novel corona virus (2019-nCoV): in silico study for corona viral drug.

abstract：:In this study, 12 compounds, which include a new flavanone 5-methoxy mundulin, were isolated from the leaves, stem bark and twigs of Mundulea sericea (Willd.) A. Chev. (Fabaceae; Papilionoideae). The structures of the compounds were identified based on spectral data analyses. The constituents of M. sericea also showed...

journal_title：Natural product research

authors： Mazimba O,Masesane IB,Majinda RR

更新日期：2012-01-01 00:00:00

abstract：:The mechanism of inhibition of jack bean and Bacillus pasteurii ureases was investigated by triacontanyl palmitate (1) which is a long-chain fatty ester and has been isolated from Symplocos racemosa Roxb. Lineweaver-Burk, Dixon plots, and their secondary replots showed that 1 is a non-competitive inhibitor of these en...

journal_title：Natural product research

authors： Lodhi MA,Abbasi MA,Choudhary MI,Ahmad VU

更新日期：2007-07-10 00:00:00

abstract：:Polyphenol concentrations were quantified by rapid resolution liquid chromatography/mass spectrometry in white table grape. The experimental vineyard was subjected to different kinds of water supply and supply rates. Samples from the same vineyards were also analysed after 6 weeks of storage in a refrigerator and afte...

journal_title：Natural product research

authors： Capriotti AL,Caruso G,Cavaliere C,Foglia P,Laganà A,Samperi R

更新日期：2012-01-01 00:00:00

abstract：:The ethanolic extract of the fruits of Momordica dioica was studied for its protective and curative effect against gentamicin-induced acute renal injury in albino rats of both sexes. Gentamicin intoxicated group showed significant increase in blood urea (69.48 +/- 4.34) and serum creatinine (3.017 +/- 0.208) from norm...

journal_title：Natural product research

authors： Jain A,Singhai AK

更新日期：2010-09-01 00:00:00

abstract：:Nine compounds were isolated from Nocardia sp. YIM 64630, and their structures were elucidated as 5'-O-acetyl-2'-deoxyuridine (1), 22E,24R-5α,6α-epoxyergosta-8(14),22-diene-3β,7α-diol (2), 22E,24R-5α,6α-epoxyergosta-8,22-diene-3β,7α-diol (3), 22E,24R-ergosta-7,22-diene-3β,5α,6β-triol (4), 5α,8α-epidioxyergosta-6,22-di...

journal_title：Natural product research

authors： Li W,Yang X,Yang Y,Qin S,Li Q,Zhao L,Ding Z

更新日期：2015-01-01 00:00:00

abstract：:In the case of Achillea wilhelmsii, 30 compounds were identified representing 94.48% of the total oil with a yield of 0.82% w/w. The major constituents of the oil were described as α-thujene (6.11%), α-pinene (5.11%), sabinene (5.23%), p-cymene (7%), 1,8-cineole (6%), linalool (10%), camphor (8.43%), thymol (18.98%) a...

journal_title：Natural product research

authors： Kazemi M,Rostami H

更新日期：2015-02-01 00:00:00

abstract：:A new ent-kaurane diterpenoid, lophanthodin G (1) and one known abietanoid, 6alpha-hydroxyferruginol (2), were isolated from the leaves of Isodon lophanthoides var. geradianus. The structure of the new compound 1 was established using spectroscopic methods including extensive 1D and 2D NMR analysis. ...

journal_title：Natural product research

authors： Liu YH,Huang SX,Zhao QS,Ding JK,Goh NK,Sun HD,Chia TF,Tan SN,Chia LS

更新日期：2008-01-01 00:00:00

abstract：:Herein we report the regioselective synthesis of podophyllotoxin-Glycosyl triazole hybrids catalysed by Ag(I)-N-heterocyclic carbene (Ag(I)-NHC) in a short reaction time (∼30 min) at ambient conditions. In principle, it is the first report of Click alkyne-azide cycloaddition catalysed by Ag(I)-NHC catalyst and moreove...

journal_title：Natural product research

authors： Nerella S,Kankala S,Gavaji B

更新日期：2021-01-01 00:00:00

abstract：:Two new cycloartane-type glycosides, caspicuside I and caspicuside II, were isolated along with two known saponins, cycloastragenol and astragaloside IV, from the roots of Astragalus caspicus. As the aglycon group, caspicuside I possesses 3beta,6alpha,16beta,(24S),25-pentahydroxycycloartane (cyclocanthagenol), while c...

journal_title：Natural product research

authors： Fathiazad F,Khosropanah MK,Movafeghi A

更新日期：2010-07-01 00:00:00

abstract：:Natural products represent a rich source of bioactive compounds that have been historically used to obtain substances with great medicinal potential. The skin of anuran amphibians is a rich source of compounds with a wide range of biological activity. Alzheimer's disease (AD) is a complex disease associated with all k...

journal_title：Natural product research

authors： Spinelli R,Aimaretti FM,López JA,Siano AS

更新日期：2019-03-31 00:00:00

abstract：:Eleven compounds were isolated from the rhizomes of Paris polyphylla Smith var. yunnanensis. Their structures were elucidated on the basis of rigorous 1D and 2D NMR experiments as well as comparison with the literature data. To the best of our knowledge, compound 1 was only predicted by UPLC/Q-TOF MSE and the NMR spec...

journal_title：Natural product research

authors： Jing S,Wang Y,Li X,Man S,Gao W

更新日期：2017-03-01 00:00:00

abstract：:Terminalia bellerica has been used as a traditional medicine in a variety of ailments including anaemia, asthma, cancer, inflammation, rheumatism and hypertension. In this study, the free radical scavenging and antioxidant activities of methanol extract (ME) and its different solvent fractions (namely hexane (HE), eth...

journal_title：Natural product research

authors： Nampoothiri SV,Binil Raj SS,Prathapan A,Abhilash PA,Arumughan C,Sundaresan A

更新日期：2011-02-01 00:00:00

abstract：:In this article, an ultra-performance liquid chromatography/quadrupole time-of-flight mass spectrometry method was developed to detect the chemical structures of proanthocyanidins (PAs) from seed coats of Schisandra chinensis. The cleavage pathways of the compounds were revealed. The structures of S. chinensis PAs, in...

journal_title：Natural product research

authors： Yan T,Hu GS,Wang AH,Hong Y,Jia JM

更新日期：2014-01-01 00:00:00

abstract：:Artemisia annua L. is an annual Eurasian desert-steppe plant. The composition of essential oils found in Artemisia annua from Russian (Buryatian) flora was analyzed in this work using gas chromatography mass-spectrometry method. Artemisia ketone, β-selinene, caryophyllene, caryophyllene oxide, germacrene D were the ma...

journal_title：Natural product research

authors： Zhigzhitzhapova SV,Dylenova EP,Gulyaev SM,Randalova TE,Taraskin VV,Tykheev ZA,Radnaeva LD

更新日期：2020-09-01 00:00:00

abstract：:Eight phenolic compounds, including two mixtures of two compounds, were isolated from the ethyl acetate extract of leaves and stems of Homalium brachybotrys. They were identified on the basis of spectroscopic data as quercetin-3-O-beta-glucopyranoside, luteolin-7-O-beta-glucopyranoside, 5,6-dihydro-6-beta-glucopyranos...

journal_title：Natural product research

authors： Mosaddik A,Forster PI,Waterman PG

更新日期：2007-11-01 00:00:00

abstract：:Two new compounds, one sesquiterpene lactone (1) and one phenylethanoid tautomer (2), together with eleven known compounds (3-13) were isolated from the leaves of Ixeridium dentatum. Their structures were determined by extensive spectroscopic methods, including 1D-, 2D-NMR, and mass spectrometry. All compounds were ev...

journal_title：Natural product research

authors： Park S,Nhiem NX,Park JH,Bhattarai KR,Chae HJ,Kim HR,Kim SH

更新日期：2019-04-10 00:00:00

abstract：:Two new anthraquinone malonylglucosides polygonins A and B were isolated from Polygonum cuspidatum along with seven known compounds. The structures of 1 and 2 were elucidated based on their spectroscopic data. ...

journal_title：Natural product research

authors： Zhang H,Zhang QW,Wang L,Zhang XQ,Ye WC,Wang YT

更新日期：2012-01-01 00:00:00

abstract：:Alzheimer's disease (AD) is a multifactorial health problem widespread over the world. Regarding the historical importance of the alkaloids in the central nervous system pharmacology they remain as promising drug candidates against AD. Seven alkaloids from Amaryllidaceae and Fabaceae were evaluated in vivo, in vitro a...

journal_title：Natural product research

authors： de Almeida WAM,de Andrade JP,Chacon DS,Lucas CR,Mariana E,de Santis Ferreira L,Guaratini T,Barbosa EG,Zuanazzi JA,Hallwass F,de Souza Borges W,de Paula Oliveira R,Giordani RB

更新日期：2020-02-18 00:00:00

abstract：:Chemical investigation of the lichen Parmotrema dilatatum led to the isolation of a new chlorinated compound, named dilatatone (1), along with a known compound, sernanderin (2). Their chemical structures were determined by analysis of their 1 D and 2 D NMR spectra, HRESIMS, and ECD data. Both compounds showed weak α-g...

journal_title：Natural product research

authors： Phan HV,Devi AP,Le HD,Nguyen TT,Nguyen HH,Le TT,Nguyen TH,Sichaem J,Duong TH

更新日期：2020-01-27 00:00:00

abstract：:A new furanodihydrobenzoxanthone, artomandin (1), together with three other flavonoid derivatives, artoindonesianin C, artonol B, and artochamin A, as well as β-sitosterol were isolated from the stem bark of Artocarpus kemando. The structures of these compounds were determined on the basis of spectral evidence. All of...

journal_title：Natural product research

authors： Ee GC,Teo SH,Rahmani M,Lim CK,Lim YM,Go R

更新日期：2011-06-01 00:00:00

abstract：:A new and efficient synthesis of a naturally occurring amide alkaloid, N-isobutyl-4,5-epoxy-2(E)-decenamide isolated from the roots of Piper nigrum has been described involving a total of nine steps. Octanal and 2-bromoacetic acid have been used as the starting materials. ...

journal_title：Natural product research

authors： Gupta N,Kaur M,Shallu,Gupta N,Kad GL,Singh J

更新日期：2013-01-01 00:00:00

abstract：:The ethanolic extract of the leaves of Eriobotrya japonica exhibited inhibitory activity against phosphodiesterase-4D (PDE4D), which is a therapeutic target of inflammatory disease. Subsequent bioassay-guided fractionation led to the isolation of a new triterpene (1), together with seven known triterpenoids, methyl co...

journal_title：Natural product research

authors： Tan BX,Yang L,Huang YY,Chen YY,Peng GT,Yu S,Wu YN,Luo HB,He XX

更新日期：2017-12-01 00:00:00

abstract：:Two new ent-atisanes ent-1β,3β,16β,17-tetrahydroxyatisane (1), ent-1β,3α,16β,17-tetrahydroxyatisane (2) together with 11 known diterpenes were isolated from the anti-tumour activity fraction of Euphorbia fischeriana Steud. The compounds were identified by detailed spectroscopic analysis, including extensive 2D-NMR exp...

journal_title：Natural product research

authors： Wang M,Wang Q,Wei Q,Li J,Guo C,Yang B,Kuang H

更新日期：2016-01-01 00:00:00

abstract：:Medicinal plants have been the main remedy to treat various ailments for a long time and nowadays, many drugs have been developed from traditional medicine. This paper reviews some medicinal plants and their main constituents which possess anti-inflammatory activities useful for curing joint inflammation, inflammatory...

journal_title：Natural product research

authors： Maione F,Russo R,Khan H,Mascolo N

更新日期：2016-06-01 00:00:00

abstract：:Pigments synthesised by Chryseobacterium sp. kr6 growing on feather waste were extracted and characterised. The pigment extract was characterised by KOH test, UV-vis, CIELAB colour system, HPLC-DAD-MS, FTIR and its antioxidant capacity was evaluated. A positive bathochromic shift was observed when kr6 colonies or pigm...

journal_title：Natural product research

authors： Jiménez MEP,Pinilla CMB,Rodrigues E,Brandelli A

更新日期：2019-06-01 00:00:00

abstract：:The iridoidic composition of Stachys glutinosa L. was examined in comparison with the results obtained in the phytochemical studies on S. corsica Pers. The presence of the known harpagide and acetyl-harpagide were showed together with that of a new di-glycosidic iridoid. The structure of this new compound, the 5-allos...

journal_title：Natural product research

authors： Serrilli AM,Ramunno A,Piccioni F,Serafini M,Ballero M,Bianco A

更新日期：2006-05-20 00:00:00

abstract：:Artemisia alba Turra (Asteraceae) is an Euro-Mediterranean plant used in Veneto (North-East of Italy) as traditional medicine for the treatment of various diseases. A. alba is a taxonomically problematic species, characterised by common polymorphism leading to a quite high variability in secondary metabolites content....

journal_title：Natural product research

authors： Peron G,Baldan V,Sut S,Faggian M,Roccabruna L,Zanini D,Manzini P,Maggi F,Dall'Acqua S

更新日期：2017-08-01 00:00:00

abstract：:Immuno-therapies are gaining more importance to treat certain forms of cancer. The goal of therapies is to enhance person's own IgG, IgA, IgM, IgD, IgE and macrophages to combat with neoplastic cells hence the effectiveness of the immune system. Since, early civilization mushrooms are considered as potent food as well...

journal_title：Natural product research

authors： Pandya U,Dhuldhaj U,Sahay NS

更新日期：2019-09-01 00:00:00

abstract：:Phytochemical study on the 95% ethyl alcohol extract of stems of Chenopodium ambrosioides resulted in the isolation of two new polyol monoterpenes, 4-hydroxy-4(α or β)-isopropyl-2-methyl-2-cyclohexen-1-one (1) and 1-methyl-4β- isopropyl-1-cyclohexene-4α,5α,6α-triol (2), together with five known compounds, (1S,2S,3R,4S...

journal_title：Natural product research

authors： Hou SQ,Li YH,Huang XZ,Li R,Lu H,Tian K,Ruan RS,Li YK

更新日期：2017-11-01 00:00:00

abstract：:Synsepalum dulcifificum is an evergreen shrub native of tropical West Africa. It is very effective against a variety of diseases. However, the phytochemical investigation on this plant is limited till now. In our current study, seventeen compounds were isolated and identified from the ethyl acetate extract of the leav...

journal_title：Natural product research

authors： Wang J,Shao S,Huang R,Wu S

更新日期：2020-10-09 00:00:00