Abstract:
:Two new compounds, one sesquiterpene lactone (1) and one phenylethanoid tautomer (2), together with eleven known compounds (3-13) were isolated from the leaves of Ixeridium dentatum. Their structures were determined by extensive spectroscopic methods, including 1D-, 2D-NMR, and mass spectrometry. All compounds were evaluated for their amylase secretion activity in human salivary gland cells after treatment in 40 mM of high glucose. All compounds showed increased amylase secretion activity. Moreover, previously undescribed compounds (1-2), luteolin 7-O-β-D-glucopyranoside (10), quercimeritrin (11), and quercetin 3-O-β-D-xylopyranoside (13) exhibited significant amylase activity, which is comparable to the positive control.
journal_name
Nat Prod Resjournal_title
Natural product researchauthors
Park S,Nhiem NX,Park JH,Bhattarai KR,Chae HJ,Kim HR,Kim SHdoi
10.1080/14786419.2019.1599885subject
Has Abstractpub_date
2019-04-10 00:00:00pages
1-6eissn
1478-6419issn
1478-6427pub_type
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