A new natural nucleotide and other antibacterial metabolites from an endophytic Nocardia sp.

abstract：:Both enantiomers of the polyketide-derived lactone citreofuran (4) have been prepared. The enantiopure building blocks were obtained on a chemoenzymatic route ((S)-6) and by a chiral pool synthesis ((R)-6). The crucial step in the synthesis, a macrolactonization, was accomplished under Mitsunobu conditions. ...

journal_title：Natural product research

authors： Bracher F,Schulte B

更新日期：2003-08-01 00:00:00

abstract：:A new protopine alkaloid, protomexicine and a new isoflavonoid, mexitin, together with 8-methoxydihydrosanguinarine, 13-oxoprotopine, rutin and quercetrin have been isolated from the aerial part of the methanolic extract of Argemone mexicana. The structures of these compounds have been established by various spectral ...

journal_title：Natural product research

authors： Singh S,Pandey VB,Singh TD

更新日期：2012-01-01 00:00:00

abstract：:Two new ditetrahydrofuran lignans, named sieverlignans A and B (1 and 2), together with six known ones (3-8), were isolated from the aerial parts of Artemisia sieversiana. Their structures were established on the basis of spectroscopic analysis including HRMS, NMR spectra and circular dichroism experiments. All the co...

journal_title：Natural product research

authors： Zhou XD,Xu XW,Shi LY,Chen SH,Zeng KW,Tu PF

更新日期：2020-01-13 00:00:00

abstract：:Salvia x jamensis J. Compton is a hybrid between Salvia greggii A. Gray and Salvia microphylla Kunt. In this study, we describe three hair types identified by Scanning Electron Microscopy. In the essential oil of the aerial parts of S. jamensis 56 different compounds were identified. The two main constituents were β-c...

journal_title：Natural product research

authors： Fraternale D,Albertini MC,Rudov A,Flamini G,Ricci D,Bisio A,Battistelli M,Accorsi A

更新日期：2013-01-01 00:00:00

abstract：:Essential oils from aerial parts of Senecio nutans, Senecio viridis, Tagetes terniflora and Aloysia gratissima were analysed by GC-MS and their antifungal activities were assayed on toxigenic Fusarium and Aspergillus species. Sabinene (27.6 ± 0.1%), α-phellandrene (15.7 ± 0.3%), o-cymene (9.6 ± 0.2%) and β-pinene (6.1...

journal_title：Natural product research

authors： Galvez CE,Jimenez CM,Gomez ALA,Lizarraga EF,Sampietro DA

更新日期：2020-05-01 00:00:00

abstract：:The aerial portions of Cynara scolymus commonly have been eaten as vegetables or functional foods by the people lived in Mediterranean region. In preliminary antioxidant screening, the rhizome portions (CSR) of this species showed better potential than leaves ones. However, neither phytochemical nor pharmacology studi...

journal_title：Natural product research

authors： Lee CL,Liao KC,Chen CC,Lin YA,Wu TY,Jhan YL,Chen CJ,Yang JC,Wu YC

更新日期：2019-07-30 00:00:00

abstract：:32 medicinal plants that are unique to the Russian Pharmacopeia have 693 isolated natural products associated with them (an average of 21.66 compounds per plant). This is in contrast to the US Pharmacopeia plants that have delivered 2366 known natural products (an average of 42.25 compounds per plant). ...

journal_title：Natural product research

authors： Chupakhin E,Babich O,Prosekov A,Asyakina L,Gureev M,Krasavin M

更新日期：2020-02-21 00:00:00

abstract：:An alternative method for the synthesis of the 8-methyl-1-tetralone from the commercially available 5-methoxy-1-tetralone has been developed. The transformation involves eight steps and affords an overall yield 25%. ...

journal_title：Natural product research

authors： Poon PS,Bedoya L,Churio GJ,Banerjee AK

更新日期：2014-01-01 00:00:00

abstract：:The ethanol extract of Stellera chamaejasme roots exhibited significant bioactivity against Peries rapae. In the course of a search for the active compounds, S-(+)-1,5-diphenyl-3-hydroxy-1-pentanone (1) was isolated and this compound has never been found before in S. chamaejasme as far as we known. The structure was e...

journal_title：Natural product research

authors： Liu Q,Jia H,Xiao B,Chen L,Zhou B,Hou TP

更新日期：2008-03-10 00:00:00

abstract：:The latex of Ficus carica Linn. (Moraceae) has been shown to possess antiviral properties against some human viruses. To determine the ability of F. carica latex (F-latex) to interfere with the infection of caprine herpesvirus-1 (CpHV-1) in vitro, F-latex was resuspended in culture media containing 1% ethanol and was ...

journal_title：Natural product research

authors： Camero M,Marinaro M,Lovero A,Elia G,Losurdo M,Buonavoglia C,Tempesta M

更新日期：2014-01-01 00:00:00

abstract：:The ethanolic extract of the fruits of Momordica dioica was studied for its protective and curative effect against gentamicin-induced acute renal injury in albino rats of both sexes. Gentamicin intoxicated group showed significant increase in blood urea (69.48 +/- 4.34) and serum creatinine (3.017 +/- 0.208) from norm...

journal_title：Natural product research

authors： Jain A,Singhai AK

更新日期：2010-09-01 00:00:00

abstract：:Alkaloids and phenolic compounds are among the most biologically active natural products from the Jacobaea/Senecio genera (Asteraceae). To isolate original natural products directly from Jacobaea gigantea crude polar extracts, centrifugal partition chromatography (CPC) was used. Previously, we reported the phytochemic...

journal_title：Natural product research

authors： Mezache N,Derbré S,Laouer H,Richomme P,Séraphin D,Akkal S

更新日期：2019-08-01 00:00:00

abstract：:A new polycyclic polyprenylated acylphloroglucinol (1), nujiangefolin D, together with five known analogues (2-6), were isolated from the fruits of Garcinia nujiangensis. Compound 1 was screened by the LC-MS and LC-PDA. The structure of 1 was elucidated on the basis of extensive spectroscopic techniques including 1 D ...

journal_title：Natural product research

authors： Tang Z,Lu L,Zhou X,Shen J,Song W,Tang Y,Xia Z

更新日期：2020-09-01 00:00:00

abstract：:Antioxidant, anticholinesterase and antidiabetic activities of three curcuminoids isolated from the Curcuma longa were simultaneously tested and compared in this study. The highest antioxidant power was detected for curcumin with the applied methods. The drug potentials of curcuminoids for Alzheimer's disease were con...

journal_title：Natural product research

authors： Kalaycıoğlu Z,Gazioğlu I,Erim FB

更新日期：2017-12-01 00:00:00

abstract：:The hexane and ethanol extracts from Himatanthus bracteatus (Apocynaceae) stems were evaluated for antiviral activity against Zika virus, yellow fever virus and dengue virus 2 and for cytotoxicity in Vero cells by MTT assay. The ethanol extract showed good antiviral activity against the three viruses with selective in...

journal_title：Natural product research

authors： da Silva ML,Stehmann JR,Serafim MSM,Vale VV,Gontijo DC,Brandão GC,Kroon EG,de Oliveira AB

更新日期：2019-11-20 00:00:00

abstract：:Phytochemical investigation of methanolic extract of Adenium obesum led to the isolation of 42 (1-42) compounds belongs to cardiac glycosides, triterpenoids and steroids. The chemical structures of isolated compounds were elucidated by spectral techniques UV, IR, NMR and FAB MS. The cardiac glycosides were tested agai...

journal_title：Natural product research

authors： Ahmed SK,Versiani MA,Ikram A,Sattar SA,Faizi S

更新日期：2017-05-01 00:00:00

abstract：:The aim of study was to compare the content of phenolic acids and flavonoids in two cultivars of Lavandula angustifolia: 'Blue River' and 'Ellagance Purple', including flowers and leafy stalks. Total phenolics and total flavonoids contents were determined by UV-Vis spectroscopy. The contents of total phenolics in leaf...

journal_title：Natural product research

authors： Adaszyńska-Skwirzyńska M,Dzięcioł M

更新日期：2017-11-01 00:00:00

abstract：:The content of total polyphenols, chlorogenic, caffeic (CaA) and ferulic acids, and rutin, was investigated in plant organs of three introgression lines (IL7-3, IL10-1 and IL12-4) of Solanum pennellii in Solanum lycopersicum cv M82 and compared with that of cropped parental. Such study aims to evidence factors associa...

journal_title：Natural product research

authors： Minutolo M,Amalfitano C,Evidente A,Frusciante L,Errico A

更新日期：2013-01-01 00:00:00

abstract：:The antibacterial activity of essential oil and methanolic extract of Teucrium polium was determined against Pseudomonas aeruginosa, Pantoea agglomerans, Brenneria nigrifluens, Rhizobium radiobacter, Rhizobium vitis, Streptomyces scabies, Ralstonia solanacearum, Xanthomonas campestris and Pectobacterium cartovorum by ...

journal_title：Natural product research

authors： Purnavab S,Ketabchi S,Rowshan V

更新日期：2015-01-01 00:00:00

abstract：:The methanolic extract of the Tanacetum gracile afforded the isolation of new sesquiterpene lactone, named gracilone (1) along with four known compounds as 14α-taraxeran-3-one (2), 14α-taraxeran-3-ol (3), apigenin (4) and β-sitosterol (5). The structure of compound 1 was elucidated on the basis of 1D, 2D NMR and MS sp...

journal_title：Natural product research

authors： Bhat G,Masood A,Ganai BA,Hamza B,Ganie S,Shafi T,Idris A,Shawl AS,Tantry MA

更新日期：2016-10-01 00:00:00

abstract：:Leishmaniasis is caused by parasites of the genus Leishmania. Recent reports about leishmaniasis show a few number of drugs available, indicating the necessity of new drugs. In this study, the ethanol extract and fractions of Pityrogramma calomelanos (L.) link. (Pteridaceae) were assayed to verify the cytotoxicity and...

journal_title：Natural product research

authors： Souza TM,Morais-Braga MF,Saraiva AÁ,Rolón M,Vega C,de Arias AR,Costa JG,Menezes IR,Coutinho HD

更新日期：2013-01-01 00:00:00

abstract：:The crystal structure and unambiguous absolute configuration of meleagrin (1) isolated from fungus Emericella dentata Nq45 is reported herein to first time on the bases of single crystal X-ray diffraction. Together with 1, haenamindole (2), isorugulosuvine (3), secalonic acid D (4), ergosterol (5) and cerebroside A (6...

journal_title：Natural product research

authors： Hamed A,Abdel-Razek AS,Araby M,Abu-Elghait M,El-Hosari DG,Frese M,Soliman HSM,Stammler HG,Sewald N,Shaaban M

更新日期：2020-03-19 00:00:00

abstract：:Momordica charantia (family, Cucurbitaceae), commonly known as karela or bitter melon (Japanese name 'Tsurureishi'), is used as a folk medicine in China, the Indian subcontinent and South America. In Chinese traditional medicine, the plant is usually used as a hypoglycaemic and anti-diabetic agent. The hypoglycaemic a...

journal_title：Natural product research

authors： Han C,Hui Q,Wang Y

更新日期：2008-01-01 00:00:00

abstract：:Meliquercifolins A (1), and B (2), two new coumarins are bearing an acetophenone derivative were isolated from the leaves of Melicope quercifolia along with three known compounds, melicodenines E (3), F (4) and I (5). Structures of two new compounds were identified based on spectroscopic analyses (UV, HR-ESI-MS, 1 D a...

journal_title：Natural product research

authors： Saputri RD,Tjahjandarie TS,Tanjung M

更新日期：2019-07-22 00:00:00

abstract：:The chemical composition of three rockrose Cistus species, Cistus monspeliensis, Cistus libanotis and Cistus villosus, collected in Tunisia, was studied by HPTLC, focusing on the terpenes and phenols constituents. Diterpenes of Cistus are important as the main constituents of the leaf sticky aromatic resin, known as l...

journal_title：Natural product research

authors： Nicoletti M,Toniolo C,Venditti A,Bruno M,Ben Jemia M

更新日期：2015-02-01 00:00:00

abstract：:A short total synthesis of natural isocarbostyril ruprechstyril (3-n-pentyl-6-methoxy-8-hydroxy-1(2H)-isoquinolinone) isolated from Ruprechtia tangarana is reported. 6,8-Dimethoxy-3-pentylisocoumarin obtained by condensation of 3,5-dimethoxyhomophthalic anhydride with hexanoyl chloride was smoothly converted to O-meth...

journal_title：Natural product research

authors： Saeed A

更新日期：2013-01-01 00:00:00

abstract：:Our laboratories have been investigating biological effects of a sesquiterpenoid polygodial and its natural and synthetic analogues. Herein, we report the evaluation of these compounds against the three forms of Trypanosoma cruzi, amastigotes, trypomastigotes and epimastigotes. Although polygodial was found to be poor...

journal_title：Natural product research

authors： Turner DN,Just J,Dasari R,Smith JA,Bissember AC,Kornienko A,Rogelj S

更新日期：2019-04-28 00:00:00

abstract：:(+) Benzomalvins E (1) and (-) Benzomalvins E (2), a pair of epimeric derivatives, together with three known benzomalvins (3-5), were isolated from solid cultures of a interrhizospheric fungus Penicillium sp. SYPF 8411. The planar structure of (+) Benzomalvins E (1) has been previously reported. While, the absolute co...

journal_title：Natural product research

authors： Feng QM,Feng Y,Zhang TY,Wang HF,Zhang MY,Wu YY,Chen G,Zhang YX,Pei YH

更新日期：2020-07-01 00:00:00

abstract：:Since the last decades, socio-economic changes have a key role on eating habits affecting the nutritional status and health of people, in particular children and adolescents. The aim of this study was to compare the diet of student population both normal weight and overweight and obese in order to understand their eat...

journal_title：Natural product research

authors： Metro D,Tardugno R,Papa M,Bisignano C,Manasseri L,Calabrese G,Gervasi T,Dugo G,Cicero N

更新日期：2018-08-01 00:00:00

abstract：:The purpose of this study is to identify the quantity and antibacterial activity of the individual phenolic compounds in Brazilian red propolis. Quantitative analysis of the 12 phenolic compounds in Brazilian red propolis was carried out using reversed-phase high-performance liquid chromatography. The main phenolic co...

journal_title：Natural product research

authors： Inui S,Hatano A,Yoshino M,Hosoya T,Shimamura Y,Masuda S,Ahn MR,Tazawa S,Araki Y,Kumazawa S

更新日期：2014-01-01 00:00:00