Abstract:
:The hexane and ethanol extracts from Himatanthus bracteatus (Apocynaceae) stems were evaluated for antiviral activity against Zika virus, yellow fever virus and dengue virus 2 and for cytotoxicity in Vero cells by MTT assay. The ethanol extract showed good antiviral activity against the three viruses with selective indexes (SI) > 10 and its fractionation led to the isolation of the known plumieride that was active only against Zika virus (SI of 15.97).
journal_name
Nat Prod Resjournal_title
Natural product researchauthors
da Silva ML,Stehmann JR,Serafim MSM,Vale VV,Gontijo DC,Brandão GC,Kroon EG,de Oliveira ABdoi
10.1080/14786419.2019.1690487subject
Has Abstractpub_date
2019-11-20 00:00:00pages
1-5eissn
1478-6419issn
1478-6427pub_type
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