Abstract:
:The methanolic extract of the Tanacetum gracile afforded the isolation of new sesquiterpene lactone, named gracilone (1) along with four known compounds as 14α-taraxeran-3-one (2), 14α-taraxeran-3-ol (3), apigenin (4) and β-sitosterol (5). The structure of compound 1 was elucidated on the basis of 1D, 2D NMR and MS spectroscopic analysis. Antimicrobial, antioxidant and anticancer activities of all compounds were evaluated, from which gracilone (1) showed a moderate antibacterial activity, while apigenin (4) showed comparatively more antibacterial activity against both gram-positive and gram-negative tested strains.
journal_name
Nat Prod Resjournal_title
Natural product researchauthors
Bhat G,Masood A,Ganai BA,Hamza B,Ganie S,Shafi T,Idris A,Shawl AS,Tantry MAdoi
10.1080/14786419.2016.1164701subject
Has Abstractpub_date
2016-10-01 00:00:00pages
2291-8issue
20eissn
1478-6419issn
1478-6427journal_volume
30pub_type
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