Abstract:
:A new triterpene, javablumine A (1) along with six known ones were isolated from the aerial parts of Sambucus javanica Blume. They were identified as 3β,23-dihydroxy-11α,12α-epoxy-urs-20(30)-en-28,13β-olide (1), ursolic acid (2), pomolic acid (3), oleanic acid (4), 2α-hydroxy-oleanolic acid (5), α-amyrin (6), and lupeol palmitate (7), respectively. Compounds 1 and 3 exhibited inhibitory effect against nitric oxide (NO) production in lipopolysaccharide (LPS)-activated RAW264.7 macrophage cell lines with IC50 values of 17.4 and 26.2 μM, respectively.
journal_name
Nat Prod Resjournal_title
Natural product researchauthors
Chen F,Liu DL,Wang W,Lv XM,Li W,Shao LD,Wang WJdoi
10.1080/14786419.2019.1596092subject
Has Abstractpub_date
2020-10-01 00:00:00pages
2816-2821issue
19eissn
1478-6419issn
1478-6427journal_volume
34pub_type
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