A immunosuppressive triterpenoid saponin from the stems of Epigynum griffithianum.

abstract：:Immature dendritic cells (iDCs) play very important roles in the pathological process of rheumatoid arthritis (RA). Therefore, it is urgent to search for natural products with antiproliferative activity on iDCs for anti-RA drug discovery. Erycibe schmidtii, a traditional Chinese medicine, has been used to treat RA in ...

journal_title：Natural product research

authors： Ren W,Wang Y,He Q,Zhou Y,Li C,Wang W,Leng X,Zeng T,Zou Q,Li L

更新日期：2020-09-01 00:00:00

abstract：:This work aimed to evaluate the content of selected phenolic natural products in the wine samples made of three new Serbian Cabernet Franc clones (Nos. 02, 010 and 012, respectively) and mother vine (used as the relevant standard) during the period 2008-2012. Compared with all other wine samples, the Cabernet Franc wi...

journal_title：Natural product research

authors： Pejin B,Stanimirovic B,Vujovic D,Popovic Djordjevic J,Velickovic M,Tesevic V

更新日期：2016-08-01 00:00:00

abstract：:The search for bioactive natural products from the rhizomes of Paris polyphylla (Trilliaceae) has resulted in the isolation of four known constituents, 1,5-dihydroxy-7-methoxy-3-methylanthraquinone (1), diosgenin-3-O-[alpha-L-rhamnopyranosyl-(1 --> 3)-beta-D-glucopyranoside] (2), diosgenin-3-O-[alpha-L-rhamnopyranosyl...

journal_title：Natural product research

authors： Devkota KP,Khan MT,Ranjit R,Lannang AM,Samreen,Choudhary MI

更新日期：2007-04-01 00:00:00

abstract：:Commiphora wightii (Arn.) Bhandari, known as guggul, produces a medicinally important gum resin which is used extensively by Ayurvedic physicians to treat various ailments. However, most of the studies on C. wightii have been limited to its gum resin. Comprehensive metabolic profiling of leaves, stem and gum resin sam...

journal_title：Natural product research

authors： Bhatia A,Tripathi T,Singh S,Bisht H,Behl HM,Roy R,Sidhu OP

更新日期：2019-01-01 00:00:00

abstract：:In this study the antioxidant and cytotoxicity activity of the Adonidia merrillii fruits were investigated using different solvent polarities (methanol, ethyl acetate and water). The results showed that the total phenolic and flavonoid contents of the methanolic extract was higher compare with other extract with respe...

journal_title：Natural product research

authors： Vafaei A,Bin Mohamad J,Karimi E

更新日期：2019-09-01 00:00:00

abstract：:As part of our search for compounds with cytotoxicity from endophytes of traditional Chinese medicines, two novel nor-sesquiterpenoids (1-2) with a new skeleton containing a tetrahydrofuran moiety were isolated form a rice medium of Fusarium tricinctum, an endophytic fungus isolated from the root of Ligusticum chuanxi...

journal_title：Natural product research

authors： Cao YM,Guo DL,Jin MY,Tan L,Yang TL,Deng F,Gu YC,Li XH,Cao ZX,Deng Y

更新日期：2020-01-24 00:00:00

abstract：:Spinacia oleracea L. (Spinach) is a leafy vegetable which is considered to have a high nutritional value. Flavonoids in spinach were reported to act as antimutagenic property. Rapid detection of these flavonoids in Spinach was achieved by using HPLC-ESI-QTOF-MS/MS. Thirty six compounds were tentatively identified base...

journal_title：Natural product research

authors： Singh A,Singh P,Kumar B,Kumar S,Dev K,Maurya R

更新日期：2019-08-01 00:00:00

abstract：:Azadirachtin-A (Aza-A, figure 1) was subjected to a variety of synthetic transformations and the antifeedant activity and toxicity of the azadirachtin derivatives were assessed against second instar larvae Spodoptera litura on castor leaves in comparison with the crude material containing 9.14% Aza-A, as well as relat...

journal_title：Natural product research

authors： Deota PT,Upadhyay PR

更新日期：2005-07-01 00:00:00

abstract：:Three species of the genus Homalium - e.g. Homalium nepalense, Homalium tomentosum and Homalium zeylanicum (Flacourtiaceae) - are recorded in India which are confined to the Eastern Ghat hill ranges. While H. zeylanicum is the IUCN red-listed medium-sized tree, the other two are endangered species of medicinal signifi...

journal_title：Natural product research

authors： Mahapatra AK,Pani SS,Sahoo AK

更新日期：2015-01-01 00:00:00

abstract：:A new cytisine-type alkaloid, along with five known alkaloids was obtained from the seeds of Sophora alopecuroides. Their structures were determined to be (-)-N-(2'-hydroxy-3',5'-di-tert-butyl-toluene)-cytisine (1), (-)-lupanine (2), (+)-matrine (3), (+)-sophoramine (4), (+)-lehmannine (5) and (-)-sophocarpine (6). Th...

journal_title：Natural product research

authors： Rong ZJ,Gao XX,Hu GS,Yan T,Jia JM,Wang AH

更新日期：2020-09-23 00:00:00

abstract：:A new triterpenic glucoside, lup-1,5,20(29)-trien-3-O-beta-D-glucopyranoside (4), along with three known phytoconstituents: n-octacosane, friedelin and beta-amyrin, has been isolated from the leaves of Clerodendrum inerme (L.) Gaertn. (Verbenaceae). Structure elucidation was carried out on the basis of chemical and ph...

journal_title：Natural product research

authors： Parveen M,Khanam Z,Ali M,Rahman SZ

更新日期：2010-01-01 00:00:00

abstract：:One new anthraquinone, 1,8-dihydroxy-2-ethyl-3-methylanthraquinone (1), together with two known compounds octadecanoic acid (2) and cholest-4-en-3-one (3) was isolated from marine actinomycete Streptomyces sp. FX-58. The structure of 1 was elucidated on the basis of spectroscopic methods, especially, the 2D-NMR spectr...

journal_title：Natural product research

authors： Huang YF,Tian L,Fu HW,Hua HM,Pei YH

更新日期：2006-11-01 00:00:00

abstract：:Polyphenol concentrations were quantified by rapid resolution liquid chromatography/mass spectrometry in white table grape. The experimental vineyard was subjected to different kinds of water supply and supply rates. Samples from the same vineyards were also analysed after 6 weeks of storage in a refrigerator and afte...

journal_title：Natural product research

authors： Capriotti AL,Caruso G,Cavaliere C,Foglia P,Laganà A,Samperi R

更新日期：2012-01-01 00:00:00

abstract：:The chemical analyses of ethyl acetate-methanol (EtOAc-MeOH) extract of muricid gastropod mollusk, Chicoreus ramosus from the southeastern coast of Indian peninsular led to the identification of unprecedented cembrane-type diterpenoid, which was characterized as (3E, 6E, 10E)-8a-butoxy-17(15→14), 20(12→11)-bis-abeo-ce...

journal_title：Natural product research

authors： Chakraborty K,Salas S,Joy M

更新日期：2020-06-01 00:00:00

abstract：:Pigments synthesised by Chryseobacterium sp. kr6 growing on feather waste were extracted and characterised. The pigment extract was characterised by KOH test, UV-vis, CIELAB colour system, HPLC-DAD-MS, FTIR and its antioxidant capacity was evaluated. A positive bathochromic shift was observed when kr6 colonies or pigm...

journal_title：Natural product research

authors： Jiménez MEP,Pinilla CMB,Rodrigues E,Brandelli A

更新日期：2019-06-01 00:00:00

abstract：:In this study, the effects of Benzoinum and Styrax on Escherichia coli (E. coli) growth were investigated by microcalorimetry. Using a TAM Air Isothermal Calorimeter, ampoule method, the power-time curves of E. coli growth at 37°C affected by Benzoinum and Styrax were measured. By analysing some quantitative thermokin...

journal_title：Natural product research

authors： Wang J,Cheng D,Zeng N,Xia H,Fu Y,Yan D,Zhao Y,Xiao X

更新日期：2011-02-01 00:00:00

abstract：:This study is designed to examine the chemical composition and antioxidant activity of the essential oil of Vitex megapotamica. Gas chromatography-mass spectrometry analysis resulted in the detection of 27 components, representing 92.36% of the total oil composition. The main components in the oil were butylated hydro...

journal_title：Natural product research

authors： de Brum TF,Boligon AA,Frohlich JK,Schwanz TG,Zadra M,Piana M,Froeder AL,Athayde ML

更新日期：2013-04-01 00:00:00

abstract：:An eremophilane-type sesquiterpenoid (EPS), 3-oxo-eremophila-1,7(11)-dien-12,8β-olide, has been isolated from anti-inflammatory folk herbs, Ligularia pleurocaulis. The aim of present study is to explore protective effects of EPS on lipopolysaccharide (LPS)-induced inflammatory responses in acute lung injury (ALI). EPS...

journal_title：Natural product research

authors： Hu Y,Yang H,Ding X,Tao L,Liu M,Zhang C

更新日期：2020-03-31 00:00:00

abstract：:Colletia paradoxa (Spreng.) Esc. (Rhamnaceae, Colletieae) is a medicinal plant, threatened with extinction in Brazil, presenting great morphological variability. Our objective is to investigate the phytochemical components, antioxidant capacity and antimycobacterial activity of different morphotypes of C. paradoxa in ...

journal_title：Natural product research

authors： Bastos Záchia NR,Piana M,Dos Santos Siqueira F,da Silva Jesus R,Athayde ML,Essi L,de Campos MMA

更新日期：2019-04-16 00:00:00

abstract：:A new germacrenolide (1) and fourteen known terpenoids (2-15) were isolated from the barks of Magnolia maudiae (Dunn) Figlar (Magnoliaceae). The structure of (7αH,11βH)-2α,8α-dihydroxy-4α,5β-epoxy-germacr-1(10)-en-6α,12-olide (1) was elucidated by physical and spectroscopic data analysis, including 1D, 2D NMR and HR-E...

journal_title：Natural product research

authors： Xianjin S,Sha S,Qi M,Zhang Z,Yang Y,Wu H,Li L,Wang W,Huang A

更新日期：2018-07-01 00:00:00

abstract：:Artemisia herba-alba is widely used in traditional medicines for the treatment of several diseases. From the aerial parts organic extract of A. herba-alba, two new compounds, 1,3,8-trihydroxyeudesm-4-en-7α,11βH-12,6α-olide (1) and 5-β-​D-​glucopyranosyloxy​-​7-methoxy-​6H-​benzopyran-​2-​one (2), respectively, togethe...

journal_title：Natural product research

authors： Mohamed TA,Abd El Aty AA,Shahat AA,Abdel-Azim NS,Shams KA,Elshamy AA,Ahmed MM,Youns SHH,El-Wassimy TM,El-Toumy SA,Hegazy MF

更新日期：2019-07-31 00:00:00

abstract：:Essential oils hydrodistilled from the leaves and stem barks of Goniothalamus macrocalyx Ban., Goniothalamus albiflorus Ban. and Goniothalamus tamirensis Pierre ex Fin. & Gagnep. growing in Vietnam were analysed by gas chromatography (GC) and GC-coupled with mass spectrometry. α-Pinene (1.7-50.0%), β-pinene (tr-6.8%),...

journal_title：Natural product research

authors： Thang TD,Huong LT,Dai DN,Ogunwande IA

更新日期：2013-01-01 00:00:00

abstract：:The essential oils obtained by hydrodistillation from the leaves of Tabernaemontana catharinensis had their composition analysed by GC-MS. A total of 18 substances were identified, consisting of a complex mixture of sesquiterpenes (83.52%), monoterpenes (5.46%) and triterpenes (4.56%). The main components in the oil w...

journal_title：Natural product research

authors： Boligon AA,Schwanz TG,Piana M,Bandeira RV,Frohlich JK,de Brum TF,Zadra M,Athayde ML

更新日期：2013-01-01 00:00:00

abstract：:Phytochemical investigation of the methylenechloride/methanol extract of the aerial parts of Stachys aegyptiaca afforded a new neoclerodane-type diterpene with a new side chain 1, in addition to two known diterpenes 2 and 3 and a known flavonoid glycoside 4. The structures of the compounds were determined by comprehen...

journal_title：Natural product research

authors： Mohamed Ael-H,Mohamed NS

更新日期：2014-01-01 00:00:00

abstract：:Six sesquiterpenoids and four lignans (1-10) were isolated from the n-BuOH extract of the rhizomes of Atractylodes lancea. Among them, the new sesquiterpenoid glycoside named (4 R, 5S, 7R)-hinesolone-11-O-β-ᴅ-glucopyranoside (1), along with three known compounds (2-4) were first obtained from this genus. All the isola...

journal_title：Natural product research

authors： Long L,Wang L,Qi S,Yang Y,Gao H

更新日期：2020-04-01 00:00:00

abstract：:Alphitobius diaperinus is an important pathogen with worldwide distribution that causes severe economic loss of efficiency in broilers. This study evaluates the potential of organic extracts of two strains entomopathogenic fungus Beauveria bassiana (CG71 and UNI40) as a biocontrol agent on A. diaperinus and promotes t...

journal_title：Natural product research

authors： Daniel JFS,Scalco AV,de Souza RM,Ocampos FMM,Barison A,Alves LFA,Neves PMOJ

更新日期：2019-10-01 00:00:00

abstract：:A new furan derivative named 3-(5-oxo-2,5-dihydrofuran-3-yl) propanoic acid (1) was isolated for the first time. Its structure was elucidated by UV, IR, NMR, HR-ESI-MS and the single-crystal X-ray diffraction spectroscopic data. Meanwhile, the antifungal and antibacterial activities of compound 1 was tested, it exhibi...

journal_title：Natural product research

authors： Yang XF,Wang NN,Kang YF,Ma YM

更新日期：2019-10-01 00:00:00

abstract：:Fourteen N,N'-diaryl unsymmetrically substituted thioureas were synthesised and their cytotoxic (in vitro), phytotoxic (in vitro), acetylcholinesterase and butrylcholinesterase activities were determined. Thiourea 16 exhibited high, and 1 and 3 showed significant phytotoxic activity. Thioureas 1, 3, 4, 6 and 10 showed...

journal_title：Natural product research

authors： Begum S,Choudhary MI,Khan KM

更新日期：2009-01-01 00:00:00

abstract：:Six new compounds, including three terpenoids (1-3) and three lignans (4-6), were isolated from the 95% EtOH extract of the twigs of Tripterygium hypoglaucum. Their structures were determined on the basis of extensive spectroscopic analysis. 9'-O-benzoyl-lariciresinol (4) showed weak cytotoxicity against HepG2/Adr cel...

journal_title：Natural product research

authors： Zheng H,Wang L,Yang T,Liu D,Li HM,Chen XQ,Li RT

更新日期：2020-07-01 00:00:00

abstract：:Two new alkaloids 6-hydroxyethyldihydrochelerythrine (1) and 6-hydroxymethyl-7,8-demethylenedihydrochelerythrine (2) together with two analogues named maclekarpine E (3) and 6-hydroxymethyldihydrosanguinarine (4) were detected primarily from the leaves of Macleaya cordata by their characteristic mass spectrometry (MS)...

journal_title：Natural product research

authors： Qing ZX,Yang P,Yu K,Yang XY,Liu JH,Xiang F,Cao HL,Cheng P,Zeng JG

更新日期：2017-07-01 00:00:00