LC-ESI-MS/MS profiling of alkaloids and antiproliferative activity of Pachypoduim lamerei drake leaves.

abstract：:(+)-7-O-Methylisomiroestrol (MeI), a novel chromene, was discovered as a phytoestrogen in the Pueraria candollei var. mirifica (Airy Shaw & Suvat.) Niyomdham (PM) root having been used as an active agent against oestrogen depletion disorders. The identification of PM phytochemicals is crucial for the development of st...

journal_title：Natural product research

authors： Yusakul G,Juengsanguanpornsuk W,Sritularak B,Phaisan S,Juengwatanatrakul T,Putalun W

更新日期：2020-02-20 00:00:00

abstract：:The ethanol extract of the Ficus carica L. leaves was tested to show strong nematicidal activity against pine wood nematode (PWN), Bursaphelenchus xylophilus, causing 90.93% corrected mortality within 72 h at 1.0 mg/mL. From the ethyl acetate soluble fraction of the F. carica L. leaves extract, the main nematicidal co...

journal_title：Natural product research

authors： Guo Q,Du G,He H,Xu H,Guo D,Li R

更新日期：2016-09-01 00:00:00

abstract：:Chemical diversity of the essential oils of twenty wild populations of Tanacetum polycephalum Sch. Bip., was investigated. The aerial parts of T. polycephalum were collected at full flowering stage from West Azerbaijan Province of Iran, air-dried; hydrodistilled to produce essential oils. The essential oils were analy...

journal_title：Natural product research

authors： Mojarrad M,Hosseini Sarghein S,Sonboli A

更新日期：2019-05-01 00:00:00

abstract：:Six compounds were isolated from the stems and leaves of Arachis hypogaea, including a new norsesquiterpene, arahyside A (1), and five known compounds, 4-(2-methoxyethyl)benzene-1,2-diol (2), (1(R,S),2(R,S))-1-phenylpropane-1,2-diol (3), tachioside (4), 1,3-benzenediol (5), demethylmedicarpin (6). Extensive spectrosco...

journal_title：Natural product research

authors： Jin WF,Luo ZH,Sun YP,Liu JS,Yu Y,Wang G,Wang GK

更新日期：2020-11-01 00:00:00

abstract：:A series of (E)-1-(4-alkyloxyphenyl)-3-(hydroxyphenyl)-prop-2-en-1-one have been successfully synthesised via Claisen-Schmidt condensation. The synthesised chalcone derivatives consisted of hydroxyl groups at either ortho, meta or para position and differed in the length of the alkyl groups, C (n) H(2) (n) (+1,) whe...

journal_title：Natural product research

authors： Ngaini Z,Fadzillah SM,Hussain H

更新日期：2012-01-01 00:00:00

abstract：:Phytochemical investigation of chloroform extract from the leaves of the marine plant Posidonia oceanica (L.) Delile (Posidoniaceae), yielded posidozinol, a new methylated sesquiterpene along with β-sitosterol and four known fatty acids: palmitic, palmitoleic, oleic and linoleic acids. The structure elucidation has be...

journal_title：Natural product research

authors： Hammami S,Salem AB,Ashour ML,Cheriaa J,Graziano G,Mighri Z

更新日期：2013-01-01 00:00:00

abstract：:One new xanthone, chryxanthone C (1), together with four known analogues (2-5), were isolated from the cultures of Paecilamyces sp. TE-540, an endophytic fungus obtained from the leaves of Nicotiana tabacum L. The structure of 1 was elucidated by comprehensive spectral analysis including HRESIMS and 1D/2D NMR, which w...

journal_title：Natural product research

authors： Li XQ,Dong QJ,Xu K,Yuan XL,Liu XM,Zhang P

更新日期：2020-10-04 00:00:00

abstract：:Juniperus chinensis cv. Kaizuca has extensive pharmacological activities. The cone oils exhibited protein tyrosine phosphatase 1B inhibitory activity in vitro. The IC50 value was 4.49 ± 0.04 μg/mL. A total of 17 compounds were characterised from the cone oils by GC-MS. In order to explain the activity against protein ...

journal_title：Natural product research

authors： Fang C,Gu D,Yang J,Li M,Liu H,Yang Y

更新日期：2018-11-01 00:00:00

abstract：:Magnolia grandiflora (Magnoliaceae) is an evergreen tree with fragrant and showy flowers native to southeastern USA but widely cultivated all over the world and used in cosmetics industry in treatment of skin diseases. Here, we report on the chemical analysis of the essential oil obtained from flowers of plants cultiv...

journal_title：Natural product research

authors： Morshedloo MR,Quassinti L,Bramucci M,Lupidi G,Maggi F

更新日期：2017-12-01 00:00:00

abstract：:The present work describes the metabolites produced by a strain identified as Streptomyces youssoufiensis, whose secondary metabolites profile has not been studied so far. The crude ethyl acetate extract was analyzed by high performance liquid chromatography-electrospray ionization mass spectrometry, leading to the de...

journal_title：Natural product research

authors： Leulmi N,Sighel D,Defant A,Khenaka K,Boulahrouf A,Mancini I

更新日期：2019-01-01 00:00:00

abstract：:Antioxidant, anticholinesterase and antidiabetic activities of three curcuminoids isolated from the Curcuma longa were simultaneously tested and compared in this study. The highest antioxidant power was detected for curcumin with the applied methods. The drug potentials of curcuminoids for Alzheimer's disease were con...

journal_title：Natural product research

authors： Kalaycıoğlu Z,Gazioğlu I,Erim FB

更新日期：2017-12-01 00:00:00

abstract：:A new and efficient synthesis of a naturally occurring amide alkaloid, N-isobutyl-4,5-epoxy-2(E)-decenamide isolated from the roots of Piper nigrum has been described involving a total of nine steps. Octanal and 2-bromoacetic acid have been used as the starting materials. ...

journal_title：Natural product research

authors： Gupta N,Kaur M,Shallu,Gupta N,Kad GL,Singh J

更新日期：2013-01-01 00:00:00

abstract：:The isolation from olive pulp of a diacylglycerol showing an oleic as well as an elenoic acid residue, the latter probably derived from a natural enzymatic oleuropein hydrolysis, is reported. The given structure is supported by 1H- and 13C-NMR data. ...

journal_title：Natural product research

authors： Marra C,Giordano ME

更新日期：2005-01-01 00:00:00

abstract：:A new eremophilane sesquiterpene, capnodiumone (1), along with five known eremophilane sesquiterpenes (2-6) and eight other compounds (7-14), have been isolated from a mangrove-associated fungus Capnodium sp. SZ-F22. The chemical structures were elucidated on the basis of extensive spectroscopic analysis. The broth ex...

journal_title：Natural product research

authors： He H,Ma Z,Wang Q,Liu Y,Xu H

更新日期：2016-07-01 00:00:00

abstract：:A new polycyclic polyprenylated acylphloroglucinol (1), nujiangefolin D, together with five known analogues (2-6), were isolated from the fruits of Garcinia nujiangensis. Compound 1 was screened by the LC-MS and LC-PDA. The structure of 1 was elucidated on the basis of extensive spectroscopic techniques including 1 D ...

journal_title：Natural product research

authors： Tang Z,Lu L,Zhou X,Shen J,Song W,Tang Y,Xia Z

更新日期：2020-09-01 00:00:00

abstract：:Our laboratories have been investigating biological effects of a sesquiterpenoid polygodial and its natural and synthetic analogues. Herein, we report the evaluation of these compounds against the three forms of Trypanosoma cruzi, amastigotes, trypomastigotes and epimastigotes. Although polygodial was found to be poor...

journal_title：Natural product research

authors： Turner DN,Just J,Dasari R,Smith JA,Bissember AC,Kornienko A,Rogelj S

更新日期：2019-04-28 00:00:00

abstract：:The study examined the radioprotective activity of an aqueous extract from Pleurotus ostreatus mycelium administered to Balb/c mice. Male mice were whole-body irradiated on day 0 ((60)Co, at 0.43 Gy/min) and divided into two groups. The extract was administered intraperitoneally to one group (100 mg/kg) on days - 10 t...

journal_title：Natural product research

authors： Llauradó G,Morris HJ,Tamayo V,Lebeque Y,Beltrán Y,Marcos J,Moukha S,Creppy EE,Bermúdez RC

更新日期：2015-01-01 00:00:00

abstract：:The antiradical activity of the freshwater bryozoan Hyalinella punctata water extracts (two samples, seasonal collection) was evaluated by using electron paramagnetic resonance spectroscopy against hydroxyl (√OH), superoxide anion (√O2(- )), methoxy (√CH2OH), carbon-dioxide anion (√CO2(- )), nitric-oxide (√NO) and 2,2...

journal_title：Natural product research

authors： Pejin B,Savic AG,Hegedis A,Karaman I,Horvatovic M,Mojovic M

更新日期：2014-01-01 00:00:00

abstract：:Two new xanthone derivatives, penixanthones A (1) and B (2), together with three known compounds, aspenicillide (3), 1,5-dihydroxy-3-methoxy-7-methyl-anthracene-9,10-dione (4) and 1,2-indandiol (5), were isolated from the ethyl acetate extract of a culture of the fungus Penicillium sp. SYFz-1, which was separated from...

journal_title：Natural product research

authors： Tao H,Wei X,Lin X,Zhou X,Dong J,Yang B

更新日期：2017-10-01 00:00:00

abstract：:This study was designed to characterise the effects of evodiamine on intestinal contractility and reveal the correlated mechanisms. Evodiamine (2.5-80.0 μM) increased normal jejunal contractility and jejunal hypocontractility established under a variety of experimental conditions. Evodiamine-exerted stimulatory effect...

journal_title：Natural product research

authors： Xiong YJ,Chen DP,Peng JY,Wang JY,Lv BC,Liu FF,Lin Y

更新日期：2015-01-01 00:00:00

abstract：:The cytotoxicity of six ent-kaurene diterpenoids isolated from the leaves of Isodon japonica (Burm.f.) Hara var. galaucocalyx (maxin) Hara was evaluated against three human tumour HepG2, GLC-82 and HL-60 cell lines through SRB assay, and their DNA damage potential (against HepG2 cell line) was assessed by comet assay....

journal_title：Natural product research

authors： Ding L,Zhou Q,Wang L,Wang W,Zhang S,Liu B

更新日期：2011-09-01 00:00:00

abstract：:Among phenolic compounds, Agave americana L. extract contained puerarin (38.4%) and p-coumaric acid (12.29%) (pCa). From the Lineweaver-Burk plots, pCa and puerarin demonstrated a competitive and a non competitive inhibitions towards human α-amylase activity, respectively. PCa exhibited a higher human inhibitory activ...

journal_title：Natural product research

authors： Sahnoun M,Bejar S,Daoud L,Ayadi L,Brini F,Saibi W

更新日期：2019-03-01 00:00:00

abstract：:Plant extracts and products have been used for centuries in traditional medicine; for most of them, in addition to the scant scientific credibility, the chemical composition and spectrum of activity are yet to be explored. To put forward this effort and to identify novel antimicrobial agents, the inhibitory activities...

journal_title：Natural product research

authors： Kumar P,Bhatt RP,Singh L,Sati OP,Khan A,Ahmad A

更新日期：2011-07-01 00:00:00

abstract：:The chemical composition and antioxidant activities of the essential oil from Nandina domestica fruits were studied for the first time. Twenty-two compounds, representing 82.79% of the oil, were identified from the oil. The major compounds were 3-hexen-1-ol (12.9%), linalool (12.3%), 2-methoxy-4-vinylphenol (9.9%), ol...

journal_title：Natural product research

authors： Bi SF,Zhu GQ,Wu J,Li ZK,Lv YZ,Fang L

更新日期：2016-01-01 00:00:00

abstract：:The chemical constituents identified in the essential oils hydrodistilled from the leaves of Amomum gagnepainii T.L.Wu, K.Larsen and Turland and Amomum repoense Pierre ex Gagnep (Zingiberaceae) of Vietnam origin are reported. The chemical analyses were performed by means of gas chromatography-flame ionisation detector...

journal_title：Natural product research

authors： Huong LT,Hung NV,Chung MV,Dai DN,Ogunwande IA

更新日期：2018-02-01 00:00:00

abstract：:The comet assay-guided fractionation of the twigs of Manglietia hookeri resulted in the isolation of three sesquiterpene-neolignans, including a new one 5-allyl-2-(4-allyl-phenoxy)-3-[7-(1-hydroxy-1-methyl-ethyl)-1, 4a-dimethyl-decahydro-naphthalen-1-yloxy]-phenol (1), and eudesobovatol A (2) and eudesobovatol B (3), ...

journal_title：Natural product research

authors： Hu X,Sui X,Wang Y,Wang W,Wu H,Zhang F,Tan Y,Zhang F

更新日期：2016-07-01 00:00:00

abstract：:The lipid peroxidation inhibitory activities of four hydroxyxanthones, isolated from the whole plant Swertia decussata, were evaluated for the first time. The most promising antioxidant among the xanthones, 1,7,8-trihydroxy-3-methoxyxanthone (swertianine, 4) was also tested for its scavenging potential against DPPH an...

journal_title：Natural product research

authors： Patro BS,Chintalwar GJ,Chattopadhyay S

更新日期：2005-06-01 00:00:00

abstract：:An HPLC/DAD/ESI-MSn method was established to characterise flavonoids in the seeds of Sophora alopecuroides L. All the flavonoids exhibited abundant [M-H]- ions, which triggered data-dependent multistage mass spectrometry fragmentations. Characteristic UV spectra were used to confirm flavonoid subtypes. In total, 22 f...

journal_title：Natural product research

authors： Yang WZ,Ye G,Meng AH,Sabir G,Qiao X,Guo DA,Ye M

更新日期：2013-03-01 00:00:00

abstract：:Jatropha mutabilis (Pohl) Baill is an endemic species of the Caatinga biome, little studied in terms of chemical composition. The objective of this work was to develop an analytical methodology to quantify vitexin in the ethanolic extract of J. mutabilis and to evaluate the expectorant and antitussive activities in mi...

journal_title：Natural product research

authors： Costa EC,Menezes PMN,Silva FS,Ribeiro LAA,Rolim LA,Araújo ECDC,Nunes XP

更新日期：2020-10-30 00:00:00

abstract：:Nerium oleander (NO), a member of the Apocynaceae family, is an ornamental plant. In this study, we evaluated the antiviral activity of hot and cold extract of NO against six different viruses such as herpes simplex virus type 1 (HSV-1), polio virus type 1 (Sb-1), vesicular stomatitis virus (VSV), reovirus type-1 (Reo...

journal_title：Natural product research

authors： Sanna G,Madeddu S,Serra A,Collu D,Efferth T,Hakkim FL,Rashan L

更新日期：2019-03-25 00:00:00