In vitro inhibitory effects of palmatine from Enantia chlorantha on Trypanosoma cruzi and Leishmania infantum.

abstract：:Artemisia herba-alba is widely used in traditional medicines for the treatment of several diseases. From the aerial parts organic extract of A. herba-alba, two new compounds, 1,3,8-trihydroxyeudesm-4-en-7α,11βH-12,6α-olide (1) and 5-β-​D-​glucopyranosyloxy​-​7-methoxy-​6H-​benzopyran-​2-​one (2), respectively, togethe...

journal_title：Natural product research

authors： Mohamed TA,Abd El Aty AA,Shahat AA,Abdel-Azim NS,Shams KA,Elshamy AA,Ahmed MM,Youns SHH,El-Wassimy TM,El-Toumy SA,Hegazy MF

更新日期：2019-07-31 00:00:00

abstract：:In the course of our efforts to search new secondary metabolites from marine-derived fungi, one new hexylitaconic acid derivative, 3-(5-methoxycarbonylpentyl)-4-methylfuran-2,5-dione (1), and two dimeric analogues asperwelwinates A and B (2 and 3), together with ten known compounds, asperitaconic acid C (4), kotanin (...

journal_title：Natural product research

authors： Han J,Yang N,Wei S,Jia J,Lin R,Li J,Bi H,Song F,Xu X

更新日期：2020-07-15 00:00:00

abstract：:The chemical composition of the essential oils isolated from the aerial parts of Anthemis arvensis L. subsp. arvensis, Anthemis cretica subsp. messanensis (Brullo) Giardina & Raimondo and from flowers and leaves of Anthemis cretica subsp. columnae (Ten.) Frezén were determinated by GC-FID and GC-MS analyses. Torreyol ...

journal_title：Natural product research

authors： Riccobono L,Maggio A,Bruno M,Spadaro V,Raimondo FM

更新日期：2017-12-01 00:00:00

abstract：:This study was designed to characterise the effects of evodiamine on intestinal contractility and reveal the correlated mechanisms. Evodiamine (2.5-80.0 μM) increased normal jejunal contractility and jejunal hypocontractility established under a variety of experimental conditions. Evodiamine-exerted stimulatory effect...

journal_title：Natural product research

authors： Xiong YJ,Chen DP,Peng JY,Wang JY,Lv BC,Liu FF,Lin Y

更新日期：2015-01-01 00:00:00

abstract：:The subfamily Asclepiadoideae (Apocynaceae) and the closely-related Periplocoideae are sources of many indigenous Indian medicinal plants. We surveyed antioxidant properties and total phenolic and flavonoid contents of 15 samples, representing 12 Indian medicinal plant species from these subfamilies. Total antioxidant...

journal_title：Natural product research

authors： Surveswaran S,Cai YZ,Xing J,Corke H,Sun M

更新日期：2010-02-01 00:00:00

abstract：:The first chemotaxonomic study based on volatile components of Porella viridissima (Mitt.) Grolle is reported. The GC-MS analysis of ether extract was performed; ten santalane and five pinguisane-type sesquiterpenes were identified together with perrottetianal A as major diterpene. Most of detected santalane-type sesq...

journal_title：Natural product research

authors： Métoyer B,Lebouvier N,Hnawia E,Thouvenot L,Wang F,Harinantenaina Rakotondraibe L,Raharivelomanana P,Asakawa Y,Nour M

更新日期：2019-08-23 00:00:00

abstract：:The oral squamous cell carcinoma (OSCC) is the eighth more common cancer in men. The development of new and more efficient drugs is needed. Plants of the genus Piper are popularly used in the treatment of many diseases. This study evaluated the antitumor effect of extract, fraction and isolated compounds from leaves o...

journal_title：Natural product research

authors： Fonseca ACCD,de Queiroz LN,Sales Felisberto J,Jessé Ramos Y,Mesquita Marques A,Wermelinger GF,Pontes B,de Lima Moreira D,Robbs BK

更新日期：2020-10-14 00:00:00

abstract：:The ability of the endophytic fungus Umbelopsis dimorpha SWUKD3.1410 to transform the triterpene nigranoic acid (3, 4-secocycloarta-4(28), 24-(Z)-diene-3, 26-dioic acid; 1) was investigated. Co-culture of nigranoic acid with U. dimorpha SWUKD3.1410 yielded six major products, including a new triterpene (2) and 5 known...

journal_title：Natural product research

authors： Wang L,Qin D,Zhang K,Huang Q,Liu S,Han MJ,Dong JY

更新日期：2017-06-01 00:00:00

abstract：:The Perovskia artemisioides Boiss. essential oil obtained by hydrodistillation method of flowers growing wild in the north of Iran. The study led to the identification of 29 compositions by a combination of HP-5 GC-FID and GC-MS analytical techniques. The constituents were identified in P. artemisioides essential oil ...

journal_title：Natural product research

authors： Hafez Ghoran S,Azadi B,Hussain H

更新日期：2016-09-01 00:00:00

abstract：:Two new monoterpene glucosides: xanmonoter A (1) and xanmonoter B (2) were isolated from Xanthium strumarium. Their structures were elucidated on the basis of 1D and 2D NMR, MS and CD analysis. Compounds 1 and 2 were tested for their anti-inflammatory activity with IC50 values of 17.4, 22.1 μM, respectively. ...

journal_title：Natural product research

authors： Jiang H,Xing X,Yan M,Guo X,Yang L,Yang L

更新日期：2019-12-01 00:00:00

abstract：:Six chemical constituents were isolated from Enicosanthum cupulare (King) Airy-Shaw. The structures of the isolated compounds were determined using 1D, 2D-NMR and were found to be identical to those previously reported for these compounds. Three aporphine alkaloids, O-methylmoschatoline, liriodenine and oxostephanine ...

journal_title：Natural product research

authors： Fujita S,Ninomiya M,Efdi M,Ohguchi K,Nozawa Y,Koketsu M

更新日期：2010-10-01 00:00:00

abstract：:Bioactivity guided fractionation of Echiochilon fruticosum Desf. (Boraginaceae) butanolic extract biautography assay against fungi led to the isolation of a new bioactive alkaloid, named saoussanabiloïde (1). Its structure was established on the basis of spectroscopic measurements, IR, MS and 2D NMR using COSY, HMQC a...

journal_title：Natural product research

authors： Hammami S,Mighri N,Ben Jannet H,Boughalleb N,Zardi-Bergaoui A,Nefzi A,Abreu P,Mighri Z

更新日期：2009-01-01 00:00:00

abstract：:A new polyoxygenated briarane-type diterpenoid, briarenol A (1), has been isolated from a gorgonian coral belonging to the genus Briareum. The structure, including the relative stereochemistry of briarane 1, was elucidated by the interpretation of spectral data. The configuration of 1 was further supported by molecula...

journal_title：Natural product research

authors： Sung PJ,Hu WP,Fang LS,Fan TY,Wang JJ

更新日期：2005-10-01 00:00:00

abstract：:Bioassay guided chemical investigation of the gorgonian Pacifigorgia senta led to the discovery of a new 19-oxygenated steroid, cholesta-5,24-diene-3β,7β,19-triol (1), as well as three known steroids (2-4). The structure of 1 was determined by extensive spectroscopic analysis, including NMR and MS spectra. All of the ...

journal_title：Natural product research

authors： Chen M,Han L,Zhang XL,Wang CY

更新日期：2016-06-01 00:00:00

abstract：:New analogues of a long-chain secondary alcohol (1) and laserine (2) were isolated from the flowers of Tamarix hampeana L. The isolated compounds were identified using 1D and 2D NMR, LCMS/APCI, and chemical methods. Laserine was isolated for the first time from T. hampeana L. ...

journal_title：Natural product research

authors： Aykac A,Akgül Y

更新日期：2010-01-01 00:00:00

abstract：:Two new steroidal alkaloids, salonine-A [(20S)-20-(N,N-dimethylamino)-3beta-(tigloylamino)-5alpha-pregn-14-en-2beta,4beta-diol] (1), and salonine-B [(20S)-20-(N,N-dimethylamino)-3beta-methoxy-pregn-5,16-diene] (2), were isolated from the MeOH extract of Sarcococca saligna, along with a known base, alkaloid-C (3). Thei...

journal_title：Natural product research

authors： Atta-ur-Rahman,Feroz F,Zaheer-ul-Haq,Nawaz SA,Khan MR,Choudhary MI

更新日期：2003-08-01 00:00:00

abstract：:Eight steroids, including five withanolides (1-5) and three other ergostane-type steroids (6-8), were isolated from the aerial parts of the halophyte Datura stramonium L., which were collected from the Yellow River Delta in China. Their structures were elucidated on the basis of extensive spectroscopic methods, especi...

journal_title：Natural product research

authors： Fang ST,Liu X,Kong NN,Liu SJ,Xia CH

更新日期：2013-01-01 00:00:00

abstract：:A new flavonol glycoside named Sabiapside A (1), along with four known compounds, quercetin-3-O-gentiobioside (2), camellianoside (3), isobariclisin-3-O- rutinoside (4), tsubakioside A (5), was isolated from Sabia parviflora. Their structures were elucidated by extensive spectroscopic analysis including MS, UV, IR and...

journal_title：Natural product research

authors： Sun Q,Pan G,Xu W,Lu X,Bai C,Liu M,Chen Y

更新日期：2019-10-29 00:00:00

abstract：:Plants mentioned in this study have numerous records in traditional Peruvian medicine being used in treatment of cancer and other diseases likely to be associated with oxidative stress. Amongst the eight plant species tested, only Dysphania ambrosioides exhibited combinatory antioxidant and anti-proliferative effect o...

journal_title：Natural product research

authors： Tauchen J,Huml L,Bortl L,Doskocil I,Jarosova V,Marsik P,Frankova A,Clavo Peralta ZM,Chuspe Zans ME,Havlik J,Lapcik O,Kokoska L

更新日期：2019-09-01 00:00:00

abstract：:The crystal structure and unambiguous absolute configuration of meleagrin (1) isolated from fungus Emericella dentata Nq45 is reported herein to first time on the bases of single crystal X-ray diffraction. Together with 1, haenamindole (2), isorugulosuvine (3), secalonic acid D (4), ergosterol (5) and cerebroside A (6...

journal_title：Natural product research

authors： Hamed A,Abdel-Razek AS,Araby M,Abu-Elghait M,El-Hosari DG,Frese M,Soliman HSM,Stammler HG,Sewald N,Shaaban M

更新日期：2020-03-19 00:00:00

abstract：:Inhibitory activity of the biocontrol bacterial strain Lysobacter capsici AZ78 is related to the production of cyclo(l-Pro-l-Tyr), a 2,5-diketopiperazine with in vitro and in vivo toxic activity against Phytophthora infestans and Plasmopara viticola. Further investigation of culture filtrate organic extracts showed it...

journal_title：Natural product research

authors： Cimmino A,Bejarano A,Masi M,Puopolo G,Evidente A

更新日期：2020-04-30 00:00:00

abstract：:Studies on the stem of Garcinia mangostana have led to the isolation of one new xanthone mangosharin (1) (2,6-dihydroxy-8-methoxy-5-(3-methylbut-2-enyl)-xanthone) and six other prenylated xanthones, alpha-mangostin (2), beta-mangostin (3), garcinone D (4), 1,6-dihydroxy-3,7-dimethoxy-2-(3-methylbut-2-enyl)-xanthone (5...

journal_title：Natural product research

authors： Ee GC,Daud S,Taufiq-Yap YH,Ismail NH,Rahmani M

更新日期：2006-10-01 00:00:00

abstract：:Phenolics were extracted from powdered pomegranate peel using water, methanol, acetone and ethyl acetate (EtOAc), respectively. The antiliperoxidant activity of the extracts on lard was studied by peroxide value method. All the extracts showed enhanced inhibitory effect on lard peroxidation with the increase of phenol...

journal_title：Natural product research

authors： Zhang Q,Jia D,Yao K

更新日期：2007-03-01 00:00:00

abstract：:Six compounds, benzyl 3-O-β-D-glucopyranosyl-7-hydroxybenzoate (1), spathulenol (2), 1,7,8-trihydroxy-2-naphtaldehyde (3), quercetin (4), astragalin (5) and 2-methoxy-4-(2-propenyl)phenyl β-D-glucoside (6), were isolated from the leaves of Melia azedarach L. The structure elucidation of compound 1 was discussed in det...

journal_title：Natural product research

authors： Zeng J,Ma RJ,Wang L,Zhang SN,Song HZ,Yang Y,Tan QG

更新日期：2019-10-01 00:00:00

abstract：:Neuroprotection under conditions of oxygen stress of two C21 steroidal glycosides, cynsaccatol Q (1) and saccatol K (2), isolated from Cynanchum auriculatum Royle ex Wight, and their potential mechanisms were studied using the model of H2O2-induced damage on PC12 cells in this paper. Experiments showed that compounds ...

journal_title：Natural product research

authors： Zhang M,Wang D,Li B

更新日期：2019-07-02 00:00:00

abstract：:The subject of this present work is a group of nine historical pictures shot in Palermo by the Sicilian photographer E. Interguglielmi in 1912. They are nine matte-collodion prints mounted on the original cardboard supports and all of them show foxing stains affecting the paper surface. In order to characterise the ch...

journal_title：Natural product research

authors： Modica A,Bruno M,Di Bella M,Alberghina MF,Brai M,Fontana D,Tranchina L

更新日期：2019-04-01 00:00:00

abstract：:This review covers the literature published since the report of the first compound to December 2006, for marine natural 2,11-cyclized cembranoids isolated from Caribbean sources, with 30 citations, most of them from 2000 to 2006, referring to compounds isolated from the Caribbean gorgonian octocorals Briareum asbestin...

journal_title：Natural product research

authors： Cóbar OM

更新日期：2009-01-01 00:00:00

abstract：:In our continuous search for cytotoxic compounds from the genus Zanthoxylum, chromatographic separation of the MeOH/CH2Cl2 (1:1) extract of Z. chalybeum yielded one new alkamide; 4-(isoprenyloxy)-3-methoxy-3,4-deoxymethylenedioxyfagaramide (1) and a known one; fagaramide (2). Similarly, from the MeOH/CH2Cl2 (1:1) extr...

journal_title：Natural product research

authors： Omosa LK,Mbogo GM,Korir E,Omole R,Seo EJ,Yenesew A,Heydenreich M,Midiwo JO,Efferth T

更新日期：2019-03-21 00:00:00

abstract：:Two new 19-hydroxy bufadienolides, named bufohydrolide A (1) and bufohydrolide B (2), and four known analogs (3-6) were isolated from the aqueous extracts of the skins of Bufo melanosticus. Their structures were established by spectral data analyses, such as UV, IR, 1 D/2D NMR and mass spectra. Compounds 1-6 were eval...

journal_title：Natural product research

authors： Meng L,Li S,Kong Q,Wang M,Zhang X,Zhu X,Yu W,Jiang N,Chun Z,Li N,Liu Y

更新日期：2020-03-23 00:00:00

abstract：:A new monoterpenoid indole alkaloid, 10-methoxyakuammidine (1), together with four known alkaloids (2-5), were isolated from the stems and leaves of Ochrosia elliptica. The structure of 1 was elucidated by extensive spectroscopic methods and the known compounds were identified by comparisons with data reported in the ...

journal_title：Natural product research

authors： Chen AH,Liu QL,Ma YL,Jiang ZH,Tang JY,Liu YP,Chen GY,Fu YH,Xu W

更新日期：2017-07-01 00:00:00