Abstract:
:A novel isoindole alkaloid named oleraisoindole (1), together with six known compounds, 7'-ethoxy-trans-feruloyltyramine (2), N-trans-feruloyltyramine (3), N-trans-feruloyl-3-methoxytyramine (4), N-trans-p-coumaroyltyramine (5) aurantiamide (6) and ferulic acid methyl ester (7) were isolated from Portulaca oleracea L. Compounds 2 and 7 were isolated for the first time from this plant. Compound 1 was identified using spectroscopic methods including HR-ESI-TOF-MS, 1D-NMR, 2D-NMR. It was tested in a nitric oxide (NO) inhibition assay and was shown to inhibit NO production in RAW 264.7 cells induced by LPS.
journal_name
Nat Prod Resjournal_title
Natural product researchauthors
Jiang M,Zhang W,Yang X,Xiu F,Xu H,Ying X,Stien Ddoi
10.1080/14786419.2017.1419226subject
Has Abstractpub_date
2018-10-01 00:00:00pages
2431-2436issue
20eissn
1478-6419issn
1478-6427journal_volume
32pub_type
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