Free radical-scavenging activities of Homalium species--An endangered medicinal plant of Eastern Ghats of India.

Abstract:

:Three species of the genus Homalium - e.g. Homalium nepalense, Homalium tomentosum and Homalium zeylanicum (Flacourtiaceae) - are recorded in India which are confined to the Eastern Ghat hill ranges. While H. zeylanicum is the IUCN red-listed medium-sized tree, the other two are endangered species of medicinal significance. The antioxidant potential of leaf and bark of the plants was evaluated through successive extraction methods by using hexane, chloroform, ethyl acetate and methanol. The extracts were subjected to in vitro assays as DPPH, hydroxyl, nitric oxide and superoxide along with its biochemical estimation. Amongst all, the ethyl acetate extracts of bark is found to be most potent compared with that of the leaves. H. nepalense has the highest amount of total phenolic and flavonoid contents followed by H. tomentosum and H. zeylanicum, respectively, and significant antioxidant behaviour.

journal_name

Nat Prod Res

journal_title

Natural product research

authors

Mahapatra AK,Pani SS,Sahoo AK

doi

10.1080/14786419.2014.987142

subject

Has Abstract

pub_date

2015-01-01 00:00:00

pages

2112-6

issue

22

eissn

1478-6419

issn

1478-6427

journal_volume

29

pub_type

杂志文章
  • Terpenoids and phenolics from Plectranthus strigosus, bioactivity screening.

    abstract::Further studies on Plectranthus sp. (Lamiaceae) led to the isolation of terpenes and phenol esters from Plectranthus strigosus Benth. ent-16-Kauren-19-ol (1), ent-16-kauren-19-oic acid (2), xylopic acid (3), xylopinic acid (4), hinokiol (5), 4 beta,6 beta-dihydroxy-1 alpha,5 beta(H)-guai-9-ene (6) 4 beta,6 beta-dihydr...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786410701654560

    authors: Gaspar-Marques C,Simões MF,Valdeira ML,Rodríguez B

    更新日期:2008-01-20 00:00:00

  • Identification of the phenolic compounds contributing to antibacterial activity in ethanol extracts of Brazilian red propolis.

    abstract::The purpose of this study is to identify the quantity and antibacterial activity of the individual phenolic compounds in Brazilian red propolis. Quantitative analysis of the 12 phenolic compounds in Brazilian red propolis was carried out using reversed-phase high-performance liquid chromatography. The main phenolic co...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2014.898146

    authors: Inui S,Hatano A,Yoshino M,Hosoya T,Shimamura Y,Masuda S,Ahn MR,Tazawa S,Araki Y,Kumazawa S

    更新日期:2014-01-01 00:00:00

  • New alkaloids from Aconitum taipaicum and their cytotoxic activities.

    abstract::Three new aconitine-type C19-diterpenoid alkaloids, taipeinines A-C (1-3), were isolated from the roots of Aconitum taipaicum. The chemical structures of these three compounds were established as (1α,6α,8α,14α,16α)-20-ethyl-8,14-dihydroxy-1,6,16-trimethoxy-4-(methoxymethyl)-aconitane (1), (1α,6α,8α,14α,16β)-20-ethyl-8...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2013.861832

    authors: Guo ZJ,Xu Y,Zhang H,Li MY,Xi K

    更新日期:2014-01-01 00:00:00

  • Histochemical investigation of Cochlospermum regium (Schrank) Pilg. leaves and chemical composition of its essential oil.

    abstract::Essential oil from Cochlospermum regium (Schrank) Pilg. leaves (CR-EO) has been extracted by hydrodistillation; we analysed the CR-EO by gas chromatography coupled with mass spectrometry. We also conducted histochemical analysis on cross-sections of the central vein of young and adult leaves. A total of 32 compounds w...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2013.879133

    authors: Inácio MC,Paz TA,Bertoni BW,Vieira MA,Marques MO,Pereira AM

    更新日期:2014-01-01 00:00:00

  • Xanthones from roots of Calophyllum thwaitesii and their bioactivity.

    abstract::Extracts from three Calophyllum species endemic to Sri Lanka were tested for antifungal and antioxidant activities. Of them, only the root methanol extract of Calophyllum thwaitesii showed activity, and the active extract on activity guided fractionation yielded four antifungal active and three inactive xanthones. Ant...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786410600899118

    authors: Dharmaratne HR,Napagoda MT,Tennakoon SB

    更新日期:2009-01-01 00:00:00

  • A new sesquiterpenoid from rhizomes of Homalomena occulta.

    abstract::A new sesquiterpeniod, 6alpha, 7alpha, 10alpha-trihydroxyisoducane (1), together with two known sesquiterpenoids, oplodiol (2) and oplopanone (3), were isolated from the chloroform extract of the rhizomes of Homalomena occulta. Their structures were elucidated by 1D and 2D NMR spectral interpretation. ...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786410802187817

    authors: Hu YM,Yang ZL,Wang H,Ye WC

    更新日期:2009-01-01 00:00:00

  • Production of camptothecin by hairy roots and regenerated transformed shoots of Ophiorrhiza rugosa var. decumbens.

    abstract::Camptothecin (CPT), the derivatives of which are used clinically for the treatment of metastatic colon cancer, is isolated from intact plants that can be subjected to environmental fluctuations. In vitro cultures may be an alternate and continuous source for year-round production of CPT. Since CPT production by undiff...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2011.559469

    authors: Kamble S,Gopalakrishnan R,Eapen S

    更新日期:2011-10-01 00:00:00

  • Effects of ethanol extract from Saururus chinensis (Bour.) Baill on lipid and antioxidant metabolisms in rats fed a high-fat diet.

    abstract::This study was performed to investigate the effect of ethanol extract from Saururus chinensis (Lour.) Baill on liver function, plasma lipid composition and antioxidant system with high-fat diet for 4 weeks. Rats were divided into the following five groups; untreated control group (normal), treated with 0.5% SE (normal...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786410701590657

    authors: Yu MH,Im HG,Lee JW,Bo MH,Kim HJ,Kim SK,Chung SK,Lee IS

    更新日期:2008-02-15 00:00:00

  • Antibacterial activity of prenylated benzopyrans from Peperomia obtusifolia (Piperaceae).

    abstract::Peperomia obtusifolia is a herbaceous perennial plant native to the Americas reported as a traditional medicine to treat snake bites and as a skin cleanser. The bioassay-guided fractionation of crude extracts from aerial parts of P. obtusifolia against a panel of clinically important fungi and bacteria, showed that he...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2019.1628751

    authors: Ruiz Mostacero N,Castelli MV,Cutró AC,Hollmann A,Batista JM Jr,Furlan M,Valles J,Fulgueira CL,López SN

    更新日期:2019-06-14 00:00:00

  • Furylhydroquinones and miscellaneous compounds from the roots of Lithospermum erythrorhizon and their anti-inflammatory effect in HaCaT cells.

    abstract::One new furylhydroquinone derivative (1) and seven known compounds (2-8) were isolated from the roots of Lithospermum erythrorhizon Sieb. et Zucc (Boraginaceae). The structure of 1 was elucidated by extensive spectroscopic methods using NMR and MS. The absolute configuration of shikonofuran J (1) was unambiguously det...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2018.1431632

    authors: Ahn J,Chae HS,Chin YW,Kim J

    更新日期:2019-06-01 00:00:00

  • Bioactive triterpenoids from the leaves of Eriobotrya japonica as the natural PDE4 inhibitors.

    abstract::The ethanolic extract of the leaves of Eriobotrya japonica exhibited inhibitory activity against phosphodiesterase-4D (PDE4D), which is a therapeutic target of inflammatory disease. Subsequent bioassay-guided fractionation led to the isolation of a new triterpene (1), together with seven known triterpenoids, methyl co...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2017.1300796

    authors: Tan BX,Yang L,Huang YY,Chen YY,Peng GT,Yu S,Wu YN,Luo HB,He XX

    更新日期:2017-12-01 00:00:00

  • Isolation and antiproliferative activity of chemical constituents from Asystasia buettneri Lindau.

    abstract::N-hexane and methanol extracts of Asystasia buettneri Lindau aerial parts exhibited antiproliferative activity on leukaemia blood carcinoma, K-562. Hexadecane (1), 1,3-propan-2-ol (9Z,12'Z,15″Z)-bis(doeicos-9,12,15-trienoate) (2), hydrocarbon, 2,3,3,10,23-pentamethyl tetraeicos-10,13,16-trien-1-ol (3), hexadecanoic ac...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2017.1360883

    authors: Hamid AA,Aiyelaagbe OO,Negi AS,Luqman S,Kaneez F

    更新日期:2018-09-01 00:00:00

  • A new analogue of fatty alcohol from Tamarix hampeana L.

    abstract::New analogues of a long-chain secondary alcohol (1) and laserine (2) were isolated from the flowers of Tamarix hampeana L. The isolated compounds were identified using 1D and 2D NMR, LCMS/APCI, and chemical methods. Laserine was isolated for the first time from T. hampeana L. ...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786410802386302

    authors: Aykac A,Akgül Y

    更新日期:2010-01-01 00:00:00

  • Chemical constituents and antitumor activity from Paris polyphylla Smith var. yunnanensis.

    abstract::Eleven compounds were isolated from the rhizomes of Paris polyphylla Smith var. yunnanensis. Their structures were elucidated on the basis of rigorous 1D and 2D NMR experiments as well as comparison with the literature data. To the best of our knowledge, compound 1 was only predicted by UPLC/Q-TOF MSE and the NMR spec...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2016.1219861

    authors: Jing S,Wang Y,Li X,Man S,Gao W

    更新日期:2017-03-01 00:00:00

  • Extraction and partial characterisation of antioxidant pigment produced by Chryseobacterium sp. kr6.

    abstract::Pigments synthesised by Chryseobacterium sp. kr6 growing on feather waste were extracted and characterised. The pigment extract was characterised by KOH test, UV-vis, CIELAB colour system, HPLC-DAD-MS, FTIR and its antioxidant capacity was evaluated. A positive bathochromic shift was observed when kr6 colonies or pigm...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2017.1423304

    authors: Jiménez MEP,Pinilla CMB,Rodrigues E,Brandelli A

    更新日期:2019-06-01 00:00:00

  • A sesquiterpenoid from Ligularia pleurocaulis modulated macrophages polarisation through TLR4 pathway.

    abstract::An eremophilane-type sesquiterpenoid (EPS), 3-oxo-eremophila-1,7(11)-dien-12,8β-olide, has been isolated from anti-inflammatory folk herbs, Ligularia pleurocaulis. The aim of present study is to explore protective effects of EPS on lipopolysaccharide (LPS)-induced inflammatory responses in acute lung injury (ALI). EPS...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2020.1736068

    authors: Hu Y,Yang H,Ding X,Tao L,Liu M,Zhang C

    更新日期:2020-03-31 00:00:00

  • Mediterranean shrubs as potential antioxidant sources.

    abstract::Several Mediterranean shrubs, both autochthonous and naturalized, have been traditionally used as food, flavouring and/or spicing agents, and as phytopharmaceuticals. The interest around 'natural' and 'biological' products is steadily increasing in developed countries. Therefore, it seems reasonable to screen some shr...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786410801997125

    authors: Sanjust E,Mocci G,Zucca P,Rescigno A

    更新日期:2008-05-20 00:00:00

  • Application of phenolic compounds as natural dye extracted from date-pits: dyeing studies of modified acrylic fibres.

    abstract::This research work involves the dyeing of acrylic fabric with natural dye extracted from date pits powders using Soxhlet extraction process. The effect of dye bath pH, salt concentration, dyeing time and temperature were studied. The optimal dyeing conditions where pH 4, 0 g/L salt, 60 min, and 80 °C. The COD and the ...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2018.1475378

    authors: Dhahri H,Guesmi A,Ben Hamadi N

    更新日期:2019-05-01 00:00:00

  • Polyphenolics from Gymnocarpos decandrus Forssk roots and their biological activities.

    abstract::Phytochemical investigation of Gymnocarpos decandrus roots lead to the isolation, characterization and evaluation of four compounds: the bis-coumarin daphnoretin, two biflavonoids: wikstrol A and wikstol B in addition to β-sitosterol glucoside. Their structures were established via spectroscopic data. The crude root e...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2019.1607336

    authors: Fathy H

    更新日期:2019-05-13 00:00:00

  • A new compound, jolynamine, from marine brown alga Jolyna laminarioides.

    abstract::A new compound, jolynamine (1), was isolated from the marine brown alga Jolyna laminarioides collected from the coast of Karachi, Pakistan. In addition, four known compounds, namely saringosterol (2), loliolide (3), methyl-4-hydroxybenzoate (4) and propyl-4-hydroxybenzoate (5), were isolated for the first time from th...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2010.509722

    authors: Khan AM,Noreen S,Imran ZP,Choudhary MI

    更新日期:2011-05-01 00:00:00

  • Antitumour activity of Prosopis cineraria (L.) Druce against Ehrlich ascites carcinoma-induced mice.

    abstract::The antitumour activity of the hydroalcoholic extract of the leaf (PCL) and stem bark (PCB) of Prosopis cineraria (L.) in Swiss albino mice was evaluated against an Ehrlich ascites carcinoma (EAC) tumour model. The activity was assessed using survival time, peritoneal cells, haematological studies, lipid peroxidation,...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2010.536159

    authors: Robertson S,Narayanan N,Raj Kapoor B

    更新日期:2011-04-01 00:00:00

  • Antibacterial activity of xanthones from Garcinia mangostana (L.) and their structure-activity relationship studies.

    abstract::Antibacterial activities of prenylated xanthones from Garcinia mangostana and their synthetic analogues were investigated, and their structure-activity relationships have been studied. γ-Mangostin has shown antibacterial activity against methicillin-resistant Staphylococcus aureus (MRSA), methicillin sensitive Staphyl...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2012.678348

    authors: Dharmaratne HR,Sakagami Y,Piyasena KG,Thevanesam V

    更新日期:2013-01-01 00:00:00

  • The genus Machaerium (Fabaceae): taxonomy, phytochemistry, traditional uses and biological activities.

    abstract::Machaerium, in the family Fabaceae, predominantly is a genus of a Neotropical distribution of trees, shrubs, and lianas occurring from southern Mexico to Brazil and northern Argentina and as far as South America. Several Machaerium species are widely used in traditional medicine and are considered to have multiple med...

    journal_title:Natural product research

    pub_type: 杂志文章,评审

    doi:10.1080/14786419.2014.1003062

    authors: Amen YM,Marzouk AM,Zaghloul MG,Afifi MS

    更新日期:2015-01-01 00:00:00

  • A new phenone from the roots of Paeonia suffruticosa Andrews.

    abstract::Thirteen phenones were obtained from the 70% ethanol extract of Paeonia suffruticosa Andrews. Their structures were determined on the basis of chemical methods and spectral data. Among them, compound 1 was identified as a new compound, and compounds 5 and 13 were obtained from genus Paeonia for the first time. The inh...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2016.1230114

    authors: Ding L,Zuo Q,Li D,Feng X,Gao X,Zhao F,Qiu F

    更新日期:2017-02-01 00:00:00

  • Bioassay-guided isolation of antibacterial constituents from Diospyros lotus roots.

    abstract::The aim of this study was to explore the extract/fractions and compounds of Diospyros lotus against various Gram-positive and Gram-negative bacteria strain. The results showed marked susceptibility of extract and its fractions against test pathogens. Among them, chloroform fraction was most dominant and effective agai...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2015.1013957

    authors: Rauf A,Uddin G,Khan H,Arfan M,Siddiqui BS

    更新日期:2016-01-01 00:00:00

  • A new highly oxygenated germacranolide from Carpesium nepalense var. lanatum (C.B.Clarke) Kitam.

    abstract::A new highly oxygenated germacranolide, carcerlane A (1), together with four known highly oxygenated germacranolides (2-5), was isolated from an ethanol extract of the whole plant of Carpesium nepalense var. lanatum (C.B.Clarke) Kitam. The structures were determined by HRESIMS and extensive analysis of their spectrosc...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2020.1833199

    authors: Yu YF,Li YQ,Wang RY,Liu X,Cui WB,Chen XH,Zhao CM,Qi FM,Zhang ZX,Fei DQ

    更新日期:2020-10-22 00:00:00

  • Solid-phase microextraction of volatile organic compounds released from leaves and flowers of Artemisia fragrans, followed by GC and GC/MS analysis.

    abstract::The chemical composition of the volatile organic compounds (VOCs) released from the leaves and flowers of Artemisia fragrans Willd. (Asteraceae) was investigated using headspace solid-phase microextraction (HS-SPME) coupled to gas chromatography (GC) and/or GS/mass spectrometry (GC/MS). The efficiency and reliability ...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786410903108951

    authors: Movafeghi A,Djozan Dj,Torbati S

    更新日期:2010-08-01 00:00:00

  • Structure confirmation of altertenuol.

    abstract::Comparison of an authentic sample of altertenuol with altenuisol obtained by total synthesis and analysis of nuclear magnetic resonance spectra unambiguously revealed that altertenuol and altenuisol are identical compounds. ...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2013.819509

    authors: Thomas R,Nemecek G,Podlech J

    更新日期:2013-01-01 00:00:00

  • New antidepressant drug candidate: Hypericum montbretti extract.

    abstract::This study was designed to investigate possible antidepressant-like effects of the extract prepared from the flowers of Hypericum montbretti Spach. (Guttiferae, Clusiaceae). Phytochemical constituents of the methanolic extract were analysed by HPLC method. The main flavonoid component was detected as rutin, and anothe...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2011.557800

    authors: Can OD,Ismail IB,Oztürk Y,Oztürk N,Potoğlu-Erkara I,Sagratini G,Ricciutelli M,Vittori S,Maggi F

    更新日期:2011-09-01 00:00:00

  • A new lumazine peptide penilumamide E from the fungus Aspergillus terreus.

    abstract::A new rare lumazine peptide, penilumamide E (1), together with 13 known compounds (2-14) were isolated from the fungus Aspergillus terreus. Their structures were identified by spectroscopic techniques. The relative configuration of 1 was confirmed by single-crystal X-ray diffraction analysis. Compound 10 exhibited ant...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2015.1101107

    authors: Chaiyosang B,Kanokmedhakul K,Boonmak J,Youngme S,Kukongviriyapan V,Soytong K,Kanokmedhakul S

    更新日期:2016-01-01 00:00:00