Free radical-scavenging activities of Homalium species--An endangered medicinal plant of Eastern Ghats of India.

Abstract:

:Three species of the genus Homalium - e.g. Homalium nepalense, Homalium tomentosum and Homalium zeylanicum (Flacourtiaceae) - are recorded in India which are confined to the Eastern Ghat hill ranges. While H. zeylanicum is the IUCN red-listed medium-sized tree, the other two are endangered species of medicinal significance. The antioxidant potential of leaf and bark of the plants was evaluated through successive extraction methods by using hexane, chloroform, ethyl acetate and methanol. The extracts were subjected to in vitro assays as DPPH, hydroxyl, nitric oxide and superoxide along with its biochemical estimation. Amongst all, the ethyl acetate extracts of bark is found to be most potent compared with that of the leaves. H. nepalense has the highest amount of total phenolic and flavonoid contents followed by H. tomentosum and H. zeylanicum, respectively, and significant antioxidant behaviour.

journal_name

Nat Prod Res

journal_title

Natural product research

authors

Mahapatra AK,Pani SS,Sahoo AK

doi

10.1080/14786419.2014.987142

subject

Has Abstract

pub_date

2015-01-01 00:00:00

pages

2112-6

issue

22

eissn

1478-6419

issn

1478-6427

journal_volume

29

pub_type

杂志文章
  • A new cycloartane triterpene bisdesmoside from the rhizomes of Actaea vaginata.

    abstract::A new cycloartane triterpene bisdesmoside, soulieoside T (1), and one known compound, oleanolic acid (2), were isolated from the ethanolic extract of the rhizomes of Actaea vaginata. Their structures were elucidated by spectroscopic methods and by comparison with data reported in the literature. Compound 1 was evaluat...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2019.1700509

    authors: Zhang M,Yang Q,Zhang X,Wu H

    更新日期:2019-12-10 00:00:00

  • Atheroprotective potentials of curcuminoids against ginger extract in hypercholesterolaemic rabbits.

    abstract::The anti-atherogenic potentials of total ginger (Zingiber officinale) extract (TGE) or curcuminoids extracted from turmeric (Curcuma longa), members of family Zingiberaceae, were compared in hypercholesterolaemia. Rabbits were fed either normal or atherogenic diet. The rabbits on atherogenic diet received treatments w...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2014.957699

    authors: Elseweidy MM,Younis NN,Elswefy SE,Abdallah FR,El-Dahmy SI,Elnagar G,Kassem HM

    更新日期:2015-01-01 00:00:00

  • Phytotoxic metabolites from Stilbocrea macrostoma, a fungal pathogen of Quercus brantii in Iran.

    abstract::Two phytotoxic furan derivatives were isolated, together with the well-known fungal and plant phytotoxin tyrosol, from the culture filtrates of Stilbocrea macrostoma. This fungal pathogen isolated from Quercus brantii trees induced wood necrosis and decline symptoms on the host plant in Iran. The two furan derivatives...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2020.1797731

    authors: Di Lecce R,Bashiri S,Masi M,Alioto D,Tuzi A,Abdollahzadeh J,Evidente A

    更新日期:2020-10-05 00:00:00

  • Biological studies of azadirachtin and its derivatives against polyphagous pest, Spodoptera litura.

    abstract::Azadirachtin-A (Aza-A, figure 1) was subjected to a variety of synthetic transformations and the antifeedant activity and toxicity of the azadirachtin derivatives were assessed against second instar larvae Spodoptera litura on castor leaves in comparison with the crude material containing 9.14% Aza-A, as well as relat...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786410512331330558

    authors: Deota PT,Upadhyay PR

    更新日期:2005-07-01 00:00:00

  • A new cytotoxic polycyclic polyprenylated acylphloroglucinol from Garcinia nujiangensis screened by the LC-PDA and LC-MS.

    abstract::A new polycyclic polyprenylated acylphloroglucinol (1), nujiangefolin D, together with five known analogues (2-6), were isolated from the fruits of Garcinia nujiangensis. Compound 1 was screened by the LC-MS and LC-PDA. The structure of 1 was elucidated on the basis of extensive spectroscopic techniques including 1 D ...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2018.1539983

    authors: Tang Z,Lu L,Zhou X,Shen J,Song W,Tang Y,Xia Z

    更新日期:2020-09-01 00:00:00

  • 2,4,5-Tribromo-1H-imidazole in the egg masses of three muricid molluscs.

    abstract::From analysis by gas chromatography/mass spectrometry (GC/MS), the presence of either 2,4,5-tribromo-1H-imidazole (1) or 3,4,5-tribromo-1H-pyrazole (2) was tentatively identified in lipophilic extracts from the egg masses of three muricid molluscs. Synthesis of these compounds, followed by comparison of the GC retenti...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/1478641031000620682

    authors: Benkendorff K,Pillai R,Bremner JB

    更新日期:2004-10-01 00:00:00

  • Analysis of peripheral T cells and the CC chemokine receptor (CCR5) delta32 polymorphism in prostate cancer patients treated with carboxymethyl-glucan (CM-G).

    abstract::β-Glucan, derived from Saccharomyces cerevisiae, is a biological response modifier which affects the innate and adaptive immune responses. The CCR5 chemokine receptor is crucial for immune cell responses. In this study, the effects of the carboxymethylated form of β-glucan (CM-G) on the lymphocyte population of CCR5 g...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2010.535159

    authors: Magnani M,Castro-Gomez RH,Aoki MN,Gregório EP,Libos F Jr,Morimoto HK,Reiche EM,Watanabe MA

    更新日期:2012-01-01 00:00:00

  • Antiproliferative and cytotoxic activity of extracts from Cistus incanus L. and Cistus monspeliensis L. on human prostate cell lines.

    abstract::Benign prostatic hypertrophy (BPH) is a common condition in elderly men that impairs quality of life and leads to a number of medical complications. The use of phytotherapeutic compounds in patients with relatively moderate BPH symptoms has been growing steadily. In the present study, acute toxicity of lyophilised aqu...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786410802583148

    authors: Vitali F,Pennisi G,Attaguile G,Savoca F,Tita B

    更新日期:2011-02-01 00:00:00

  • Isolation of chemical constituents from Enicosanthum cupulare (King) Airy-Shaw.

    abstract::Six chemical constituents were isolated from Enicosanthum cupulare (King) Airy-Shaw. The structures of the isolated compounds were determined using 1D, 2D-NMR and were found to be identical to those previously reported for these compounds. Three aporphine alkaloids, O-methylmoschatoline, liriodenine and oxostephanine ...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786411003774338

    authors: Fujita S,Ninomiya M,Efdi M,Ohguchi K,Nozawa Y,Koketsu M

    更新日期:2010-10-01 00:00:00

  • Two new benzoic acid derivatives from endophytic fungus Aspergillus versicolor.

    abstract::Two new benzoic acid derivatives, named methyl(S)-3-hydroxy-4-(2- hydroxy -6-methylheptan-2-yl)benzoate (1) and 2-hydroxy-3-(6- hydroxy-6-methylhept-1-en-2-yl)benzoic acid (2), were isolated from the ethanol extract of an endophytic fungus Aspergillus versicolor derived from the medicinal plant Euphorbia royleana. The...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2020.1777121

    authors: Ye Y,Chen Y,Hou Y,Yu H,Zhu L,Sun Y,Zhou M,Chen Y,Dong M

    更新日期:2020-06-11 00:00:00

  • Antibacterial activity of xanthones from Garcinia mangostana (L.) and their structure-activity relationship studies.

    abstract::Antibacterial activities of prenylated xanthones from Garcinia mangostana and their synthetic analogues were investigated, and their structure-activity relationships have been studied. γ-Mangostin has shown antibacterial activity against methicillin-resistant Staphylococcus aureus (MRSA), methicillin sensitive Staphyl...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2012.678348

    authors: Dharmaratne HR,Sakagami Y,Piyasena KG,Thevanesam V

    更新日期:2013-01-01 00:00:00

  • A new cinnamoylglycoflavonoid, antimycobacterial and antioxidant constituents from Heritiera littoralis leaf extracts.

    abstract::A new cinnamolyglycoflavonoid 3-cinnamoyltribuloside (1), its precursor tribuloside and two known flavonoid glycosides afzelin and astilbin were isolated from Heritiera littoralis Dryand (Sterculiaceae) ethanolic leaf extract. The dichloromethane leaf extract afforded two known pentacyclic triterpenoids, 3β-taraxerol ...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2013.863202

    authors: Christopher R,Nyandoro SS,Chacha M,de Koning CB

    更新日期:2014-01-01 00:00:00

  • Chemotaxonomy and cytotoxicity of the liverwort Porella Viridissima.

    abstract::The first chemotaxonomic study based on volatile components of Porella viridissima (Mitt.) Grolle is reported. The GC-MS analysis of ether extract was performed; ten santalane and five pinguisane-type sesquiterpenes were identified together with perrottetianal A as major diterpene. Most of detected santalane-type sesq...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2019.1655022

    authors: Métoyer B,Lebouvier N,Hnawia E,Thouvenot L,Wang F,Harinantenaina Rakotondraibe L,Raharivelomanana P,Asakawa Y,Nour M

    更新日期:2019-08-23 00:00:00

  • Briarenol A, a new diterpenoid from a gorgonian '\Briareum sp. (Briareidae).

    abstract::A new polyoxygenated briarane-type diterpenoid, briarenol A (1), has been isolated from a gorgonian coral belonging to the genus Briareum. The structure, including the relative stereochemistry of briarane 1, was elucidated by the interpretation of spectral data. The configuration of 1 was further supported by molecula...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786410512331330611

    authors: Sung PJ,Hu WP,Fang LS,Fan TY,Wang JJ

    更新日期:2005-10-01 00:00:00

  • Protective effect of Epicatechin on APAP-induced acute liver injury of mice through anti-inflammation and apoptosis inhibition.

    abstract::Epicatechin (EC) is the most effective compound in Euonymus alatus (Thunb.)Sieb, and possesses a series of benefits, including anti-inflammatory, antioxidant, antiobesity and anticancer effects. In this study, we investigated the protective effects of EC in Acetaminophen(N-acetyl-p-aminophenol, APAP)-induced acute liv...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2018.1503261

    authors: Wu H,Xie Y,Xu Y,Hu Z,Wan X,Huang H,Huang D

    更新日期:2020-03-01 00:00:00

  • Fatty acid composition of seeds of some species of Nepeta L.

    abstract::The fatty acid compositions of Nepeta viscida, N. cilicica, N. crinita, N. nuda ssp. glandulifera and N. aristata were analyzed by GC/MS. The main free fatty acids were found as linolenic acid (49.8-58.5%), linoleic acid (10.9-23.5%), oleic acid (11.5-19.2%), palmitic acid (5.2-6.8%) and stearic acid (2.0-3.7%) and, t...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786410601129473

    authors: Kiliç T,Dirmenci T,Gören AC

    更新日期:2007-05-01 00:00:00

  • New monoterpene glycosides from the root cortex of Paeonia suffruticosa and their potential anti-inflammatory activity.

    abstract::The methanol extract of the root cortex of Paeonia suffruticosa afforded two new monoterpene glycosides, paeoniside A (1) and paeoniside B (2), and three known monoterpene glycosides, paeoniflorin (3), benzoylpaeoniflorin (4) and 4-O-methyl-paeoniflorin (5). Their structures were elucidated on the basis of spectroscop...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2013.858340

    authors: Zhu X,Fang ZH

    更新日期:2014-01-01 00:00:00

  • Adherence to the Mediterranean diet in a Sicilian student population.

    abstract::Since the last decades, socio-economic changes have a key role on eating habits affecting the nutritional status and health of people, in particular children and adolescents. The aim of this study was to compare the diet of student population both normal weight and overweight and obese in order to understand their eat...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2017.1402317

    authors: Metro D,Tardugno R,Papa M,Bisignano C,Manasseri L,Calabrese G,Gervasi T,Dugo G,Cicero N

    更新日期:2018-08-01 00:00:00

  • Optimisation of Bjerkandera adusta culture conditions for the production of α-α-trehalose.

    abstract::Several factors affect the vegetative growth of fungi, such as temperature, pH, and culture medium. In addition to mycelial growth, these factors affect metabolite production. There are limited studies that have identified the metabolites produced by the fungus Bjerkandera adusta, which have potential biotechnological...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2020.1758092

    authors: Rech KS,de Oliveira CF,Moura PF,de Oliveira CDSP,Hirota BCK,de Oliveira M,Rüdiger AL,de Sá EL,Miguel OG,Auer CG,Miguel MD

    更新日期:2020-05-06 00:00:00

  • Synthesis of 4-hydroxy-3,4-dialkyl-2,6-diaryl-piperidine derivatives as potent antimicrobial agent.

    abstract::A series of 4-hydroxy-3,4-dialkyl-2,6-diaryl-piperidine (7-12) have been synthesised by reduction of 3-alkyl-2,6-diarylpiperidin-4-one using the Grignard reagent. Structural assignments and conformational analysis of the compounds were established based on the spectral studies. All the piperdin-4-ol derivatives (7-12)...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2012.671317

    authors: Maruthavanan T,Venkatesan P

    更新日期:2013-01-01 00:00:00

  • A new flavone from Malaysia Borneo Marsdenia tinctoria.

    abstract::Marsdenia tinctoria is an indigo producing plant commonly found in Borneo, Malaysia. In this present study, one new flavone kapitone (1) and three known compounds, that is 3,2'-dihydroxyflavone (2), 1-methylcyclobutene (3) and dimethyl isatoate (4) were isolated from the Malaysia Borneo M. tinctoria R. Br. (Apocynacea...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2015.1118629

    authors: Mohd Nasuha NA,Choo YM

    更新日期:2016-07-01 00:00:00

  • Agronomic, metabolomic and lipidomic characterisation of Sicilian Origanum vulgare (L.) ecotypes.

    abstract::Although Origanum vulgare (L.) has been deeply analysed at phytochemical level, poor knowledge is available regarding non-volatile compounds such as lipids. The aim of this work was to characterise five wild Sicilian Origanum ecotypes from an agronomic, metabolomic and lipidomic perspective. Serradifalco presented hig...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2015.1104672

    authors: Tuttolomondo T,Martinelli F,Mariotti L,Leto C,Maggio A,La Bella S

    更新日期:2016-01-01 00:00:00

  • Antiproliferative and antiviral activity of methanolic extracts from Sardinian Maltese Mushroom (Cynomorium coccineum L.).

    abstract::Cynomorium coccineum is a non-photosynthetic plant that grows in Mediterranean countries and that is amply used in the traditional medicine. The aim of this study was to extend previous studies on the chemical and biological properties of C. coccineum, evaluating the potential antiviral and antiproliferative activity ...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2019.1678613

    authors: Vascellari S,Zucca P,Perra D,Serra A,Piras A,Rescigno A

    更新日期:2019-10-17 00:00:00

  • Antiplasmodial activity of a novel diarylheptanoid from Siphonochilus aethiopicus.

    abstract::The Nigerian and South African varieties of Siphonochilus aethiopicus were examined for their phytochemical constituents. The ethyl acetate extract of the rhizomes of the South African variety yielded a novel diarylheptanoid, 2,3-diacetoxy-7-(3'',4''-dihydroxy-5''-methoxyphenyl)-1-(4'-hydroxy-3'-methoxyphenyl)-5-hepte...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2020.1799358

    authors: Igoli NP,Al-Tannak NF,Ezenyi IC,Gray AI,Igoli JO

    更新日期:2020-07-27 00:00:00

  • Design, synthesis and agricultural evaluation of derivatives of N-Acyl-N-(m-fluoro-benzyl)-6-amino-coumarin.

    abstract::ABTRACT This study aims to design and synthesize a series of N-Acyl-N-(m-fluoro- benzyl)-6- amino-coumarins through the principle of active substructure stitching, which are based on the core structure of N-(m-fluoro-benzyl)-6-amino-coumarin. The structures of target compounds e1-e25 have been characterized by 1H NMR,...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2020.1806268

    authors: Jin Y,Ding YH,Dong JJ,Wei Y,Hao SH,Feng BC

    更新日期:2020-08-13 00:00:00

  • Evaluation of the anti-Leishmania activity of ethanol extract and fractions of the leaves from Pityrogramma calomelanos (L.) link.

    abstract::Leishmaniasis is caused by parasites of the genus Leishmania. Recent reports about leishmaniasis show a few number of drugs available, indicating the necessity of new drugs. In this study, the ethanol extract and fractions of Pityrogramma calomelanos (L.) link. (Pteridaceae) were assayed to verify the cytotoxicity and...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2012.686911

    authors: Souza TM,Morais-Braga MF,Saraiva AÁ,Rolón M,Vega C,de Arias AR,Costa JG,Menezes IR,Coutinho HD

    更新日期:2013-01-01 00:00:00

  • A new denudatine type C20-diterpenoid alkaloid from Aconitum sinchiangense W. T. Wang.

    abstract::A new denudatine-type C20-diterpenoid alkaloid, designated as sinchianine (1), together with eight known diterpenoid alkaloids, 12-acetyl-12-epi-napelline (2), 12-epi-napelline (3), neoline (4), talatisamine (5), 14-O-acetylsenbusine A (6) and benzoylaconine (7), songorine (8) and aconitine (9), were isolated from the...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2017.1410814

    authors: Samanbay A,Zhao B,Aisa HA

    更新日期:2018-10-01 00:00:00

  • Characterisation of the metabolites of an antibacterial endophyte Botryodiplodia theobromae Pat. of Dracaena draco L. by LC-MS/MS.

    abstract::Botryodiplodia theobromae Pat. belongs to the endophytic fungi that live within the tissues of medicinal plants and produce bioactive natural products. The endophyte was isolated from the leaves of Dracaena draco L. The LC-MS-based metabolite fingerprinting of the ethyl acetate extract of B. theobromae with antibacter...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2015.1012715

    authors: Zaher AM,Moharram AM,Davis R,Panizzi P,Makboul MA,Calderón AI

    更新日期:2015-01-01 00:00:00

  • A new lignan glycoside from the aerial parts and cytotoxic investigation of Uvaria rufa.

    abstract::Chemical investigation of the aerial parts of Uvaria rufa (Dunal) Blume collected from Vietnam yielded one new lignan glycoside, ufaside (1), along with six known compounds, oxoanolobine (2), ergosta-4,6,8(14),22-tetraen-3-one (3), catechin (4), epicatechin (5), daucosterol (6) and glutin-5-en-3-one (7). Their chemica...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2014.971790

    authors: Nguyen TH,Ho VD,Do TT,Bui HT,Phan VK,Sak K,Raal A

    更新日期:2015-02-01 00:00:00

  • Effect of meteorological parameters and regions on accumulation pattern of phenolic compounds in different mulberry cultivars grown in China.

    abstract::The compositions of phenolic compounds in 10 cultivars of two mulberry species (Morus atropurpurea Roxb. and Morus alba Linn.) grown in four regions of China were analysed using HPLC-TOF-MS. Results showed that a total of 27 phenolic compounds were identified in these mulberry cultivars. The Taiwan cultivar from the J...

    journal_title:Natural product research

    pub_type: 杂志文章

    doi:10.1080/14786419.2016.1274895

    authors: Yang J,Zhang X,Jin Q,Gu L,Liu X,Li J,Ni Y

    更新日期:2017-05-01 00:00:00